Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 5 de 5
Filtrar
2.
J Cardiothorac Vasc Anesth ; 31(6): 1966-1973, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28711314

RESUMO

OBJECTIVE: Postoperative delirium (POD) is a common complication after cardiac surgery and is associated with increased patient morbidity and mortality. The objective of this study was to identify risk factors for long duration and overall burden of POD after cardiac surgery. DESIGN: One-year, single-center, retrospective, observational cohort study. SETTING: University hospital. PARTICIPANTS: Adult patients undergoing cardiac surgery with cardiopulmonary bypass in 2013. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Patients were screened for POD using the Intensive Care Delirium Screening Checklist. The primary outcome measure was the incidence of POD. Secondary outcome measures were the duration of POD and the area under the curve determined using the Intensive Care Delirium Screening Checklist score over time. Independent predictors of POD were estimated in multivariable logistic regression models. Hospital length of stay, medications, and outcome data also were analyzed. Among the 656 patients included in the cohort, 618 were analyzed. The overall incidence of POD was 39%. Older patient age (odds ratio [95% confidence interval]) 1.06 [1.04-1.09] for an increase of 1 year, p < 0.001); low preoperative serum albumin (1.08 [1.03-1.13] for a decrease of 1 g/L, p < 0.001); a history of atrial fibrillation (2.30 [1.30-4.09], p = 0.004); perioperative stroke (6.27 [1.54-43.64], p = 0.008); ascending aortic replacement surgery (2.99 [1.50-6.05], p = 0.002); longer duration of procedure (1.37 [1.16-1.63] for an increase of 1 hour, p < 0.001); and increased postoperative C-reactive protein concentration (2.16 [1.49-3.16] for a 2-fold increase, p < 0.001) were associated with higher odds of POD. Among patients affected by POD, older age, perioperative stroke, longer procedure time, and increased postoperative C-reactive protein were consistently predictive of longer duration of POD and greater area under the curve. CONCLUSIONS: Known risk factors for the development of POD after cardiac surgery also are predictive of prolonged duration and high overall burden of POD.


Assuntos
Procedimentos Cirúrgicos Cardíacos/efeitos adversos , Efeitos Psicossociais da Doença , Delírio/diagnóstico , Delírio/etiologia , Complicações Pós-Operatórias/diagnóstico , Complicações Pós-Operatórias/etiologia , Adulto , Fatores Etários , Idoso , Proteína C-Reativa/metabolismo , Procedimentos Cirúrgicos Cardíacos/tendências , Estudos de Coortes , Delírio/sangue , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Duração da Cirurgia , Complicações Pós-Operatórias/sangue , Valor Preditivo dos Testes , Estudos Prospectivos , Estudos Retrospectivos , Fatores de Risco , Fatores de Tempo
3.
Eur J Cardiothorac Surg ; 25(5): 691-4, 2004 May.
Artigo em Inglês | MEDLINE | ID: mdl-15082268

RESUMO

OBJECTIVES: Risk-stratification in cardiac surgical procedures is of major interest. Recent studies have shown, that the EuroSCORE is a very good and reliable risk-stratification score in CABG and in valve surgery. The aim of the study was to evaluate the EuroSCORE in patients undergoing surgery on the thoracic aorta. METHODS: Three hundred and sixty-seven consecutive patients underwent surgery of the thoracic aorta and were scored, according to the additive and logistic EuroSCORE algorithm. We compared correlation of predicted and observed mortality and evaluated a modification of the EuroSCORE in order to improve the scoring system. Score validity was assessed by calculating the area under the receiver operating characteristic curve (ROC). RESULTS: Overall hospital mortality was 10.1%. Additive EuroSCORE predicted mortality was 2.3% for 3-6% risk, 12.9% for 7-8% risk, 18.4% for 9-12% risk and 27.3% for a risk >12%. The modified score predicted mortality was 1% for 3-6% risk, 8.2% for 7-8% risk, 12.1% for 9-14% risk, 18.6% for 15-24% risk and 28.6% for a risk >24%. Area under the ROC-curve was 0.68 for the EuroScore and 0.91 in the modified score, 0.72 and 0.86 in the logistic model. CONCLUSIONS: The modified score, taking into account aortic dissection (6 points) and preoperative malperfusion (12 points) significantly improves the predictive value of the EuroSCORE in patients undergoing thoracic aortic surgery.


Assuntos
Aneurisma da Aorta Torácica/cirurgia , Dissecção Aórtica/cirurgia , Indicadores Básicos de Saúde , Doença Aguda , Idoso , Algoritmos , Aorta Torácica/cirurgia , Área Sob a Curva , Implante de Prótese Vascular , Feminino , Mortalidade Hospitalar , Humanos , Masculino , Pessoa de Meia-Idade , Prognóstico , Medição de Risco/métodos , Resultado do Tratamento
4.
Ann Thorac Surg ; 75(4): 1318-21, 2003 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-12683589

RESUMO

In surgical procedures, and specifically in cardiovascular operations, the polypropylene monofilament is a widely used suture material. We report an unexplained case of early rupture of a 4-0 polypropylene suture used for the distal anastomosis after replacement of the ascending aorta with a Dacron (Vaskutek, Sulzer Medica, Austin, TX) prosthesis. By trying to identify if intraoperative mechanical damage could have led to the rupture, we obtained impressive results of how different manipulations of suture material using surgical instruments can damage those delicate filaments. Pictures were obtained by light microscopy and electron microscopy.


Assuntos
Aorta/cirurgia , Polipropilenos , Suturas , Aneurisma Aórtico/cirurgia , Feminino , Humanos , Pessoa de Meia-Idade , Reoperação , Estresse Mecânico
5.
Eur J Cardiothorac Surg ; 21(1): 10-4, 2002 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-11788248

RESUMO

OBJECTIVE: Assessment of quality of life (QL) in patients undergoing major surgical procedures is of increasing interest. We focused on surgery of the thoracic aorta requiring deep hypothermic circulatory arrest (DHCA). Aim of this study was to assess QL after thoracic aortic surgery with DHCA, using the Short Form 36 Health Survey (SF-36) questionnaire. METHODS: Between 01/94 and 12/99 212 (59.1%) out of a total of 359 interventions on the thoracic aorta were performed under DHCA, with an early mortality of 13.7% (28 patients). During an average follow-up of 3.2+/-1.3 years, 27 patients died (15.2%) and five patients (2.8%) were lost. A total of 145 patients (81.9%) had a complete follow-up. RESULTS: 125 of the 145 SF-36 questionnaire handed out were answered correctly (86.2%). In relation to a standard population (z=0), the most important deficits were found in physical function (z=-0.53) and role limitations because of physical health (z=-0.42). Good results were found regarding the aspect of pain (z=0.28), social functioning (z=0.02) and vitality (z=-0.02). Overall QL in patients having been operated for aortic aneurysm was better than for patients with acute type A-dissection. CONCLUSION: Despite restrictions in physical functioning and role limitation because of physical health, QL in patients after interventions on the thoracic aorta with DHCA is fairly good and, for patients being operated for aortic aneurysm, comparable to an age-matched standard population. Patients having being operated electively for aortic aneurysm enjoyed a better QL than patients having been operated emergently for acute type A dissection.


Assuntos
Aorta Torácica/cirurgia , Indicadores Básicos de Saúde , Parada Cardíaca Induzida , Qualidade de Vida , Procedimentos Cirúrgicos Vasculares , Idoso , Feminino , Humanos , Hipotermia Induzida , Masculino , Pessoa de Meia-Idade , Período Pós-Operatório
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA