Assessment of different factors on the influence of glass wool concentration for detection of main swine viruses in water samples.

Viruses existed in wastewaters might pose a biosecurity risk to human and animal health. However, it is generally difficult to detect viruses in wastewater directly as they usually occur in low numbers in water. Therefore, processing large volumes of water to concentrate viruses in a much smaller final volume for detection is necessary. Glass wool has been recognized as an effective material to concentrate multiple in water, and in this study, we assessed the use of glass wools on concentrating pseudorabies virus (PRV), African swine fever virus (ASFV), and porcine epidemic diarrhea virus (PEDV) in water samples. The influence of pH values, water matrix, water volume, filtration rate, temperature on the effect of the method concentrating these viruses for detection was evaluated in laboratory. Our results revealed that glass wool was suitable for the concentration of above-mentioned viruses from different water samples, and demonstrated a good application effect for water with pH between 6.0-9.0. Furthermore, glass wool also showed a good recovery effect on concentrating viral nucleic acids and viral particles, as well as living viruses. In addition, combining use of glass wool with skim milk, polyethylene glycol (PEG)-NaCl, or ultracentrifuge had good effects on concentrating ASFV, PRV, and PEDV. Detection of wastewater samples (n = 70) collected from 70 pig farms in 13 regions across Hubei Province in Central China after glass-wool-concentration determined one sample positive for ASFV, eighteen samples positive for PRV, but no sample positive for PEDV. However, these positive samples were detected to be negative before glass wool enrichment was implemented. Our results suggest that glass wool-based water concentration method developed in this study represents an effective tool for detecting viruses in wastewater.

Dynamic Assessment and Sustainability Strategies of Ecological Security in the Irtysh River Basin of Xinjiang, China.

The drylands of China are extensive, and they are home to more than one-third of the country's population. However, the watershed territories of the drylands, where the majority of human activities are concentrated have long experienced strained human-land relationships, culminating in ecological security concerns. Correspondingly, it is essential to carry out a comprehensive assessment of the ecological security of dryland watersheds and to identify the key factors influencing ecological security in order to formulate strategies that ensure the sustainability of drylands. Premised on the Driving-Pressure-State-Impact-Response (DPSIR) model, this study developed an ecological security index and applied it to the Irtysh River Basin of Xinjiang, China, from 2000 to 2020. The obstacle degree model was applied to reveal the obstacles in two dimensions: criterion level and indicator level. The findings suggested that the ecological security comprehensive index in the Irtysh River Basin has increased significantly from 2000 to 2020, irrespective of the fact that it decreased during the study period and then increased. The ecological security level changed from 'critically safe' in 2000 to 'general safety' in 2020, with the state subsystem and pressure subsystem becoming ecological security weaknesses. The primary factors influencing the ecological security of the study area were water consumption, the area of high-efficiency water-saving irrigation, the proportion of wetland area, vegetation coverage, and livestock population. The ecological security of different counties in the basin varies greatly, whereas the factors that influence ecological security showed both similarities and differences among the counties. In light of on the findings, we proposed that future strategies for ecological security enhancement should concentrate on enacting the policy of localizing spatial differentiation, optimizing industrial structure, strengthening scientific and technological support in the field of water conservation, bolstering the treatment capacity of environmental facilities, and implementing the Mountains-Rivers-Forests-Farmlands-Lakes-Grasslands System to support the sustainable development of dryland watersheds.

Low-cost composite film triboelectric nanogenerators for a self-powered touch sensor.

In the last two decades, nanogenerators have been studied inorder to solve the power supply problems of electronic devices. Triboelectric nanogenerators (TENGs) have gained widespread attention due to their excellent properties and wide range of applications. However, previous studies frequently ignored numerous application-related issues and even wasted some of the benefits of the TENG itself in favor of enhanced performance. Here, we propose a TENG based on BaTiO3 (BTO)-polydimethylsiloxane (PDMS) composite films with low cost and simple preparation, where its maximum output performance is obtained when the mass proportion of BTO to PDMS is 40%. In addition, we demonstrate how the single-electrode TENG may be used as a self-powered touch sensor that can communicate with a microcontroller unit (MCU) to turn LED lights on and off. This practical example will provide a valuable reference for the application of low-cost self-powered sensors in wearable devices, Internet of Things, human-machine interactions and other fields. Furthermore, we discovered a number of issues that were rarely or never addressed in previous studies and provide some solutions, such as a signal processing method for a TENG-based self-powered sensor. It serves as a foundation for future investigations on the performance assessment and application of TENGs.

Do Rural-Urban Identities Affect Individuals' Health? Evidence From China.

We study the relationship between household registration status (Hukou) and the state of individuals' health to find out whether inequality in health between urban and rural population exists in China. We have used the probit model to regress the state of health on household registration using the individual-level data of the 2018 CFPS survey. We find that inequality in health between urban and rural population does exist in China. Individuals with rural Hukou have a higher probability by 1.4% to be admitted to hospital than individuals with urban Hukou. While, individuals with rural Hukou tend to over-estimate the state of their health as the probability for them to assess themselves healthy is higher by 1.7% than individuals with urban Hukou. The findings suggest that policy makers should recognize the issue of rural-urban health inequalities and take measures, such as controlling pollution in rural areas and providing high quality routine health checks for rural population to deal with the problem.

[Concentration Analysis and Health Risk Assessment of Air Pollutants in Newly Decorated Public Places in Xi'an].

In order to understand the levels of indoor air pollution and health risks in public places, our research group conducted air quality monitoring and human health risk assessments for five types of public places (offices, classrooms, laboratories, banks, and hospitals) in Xi'an City from December 2017 to July 2020. The test items included formaldehyde, benzene, toluene, xylene, n-butyl acetate, ethylbenzene, styrene, n-undecane, and total volatile organic compounds (TVOC). The results showed that formaldehyde had the highest exceedance rate (59.4%), followed by toluene, TVOC, benzene, and xylene. Among the five types of public places, hospitals had the highest rate of pollutants exceeding the standard (46.7%), and the main pollutants exceeding the standard were formaldehyde, benzene, and toluene. The results showed that the concentrations of formaldehyde and TVOC were positively correlated with temperature and humidity. The health risk assessment results showed that there were carcinogenic risks of formaldehyde and benzene in different places; people working in banks had a higher risk of formaldehyde carcinogenesis, and those working in hospitals had a higher risk of benzene carcinogenesis. This study provides a reference for the level of indoor air pollution in public places in Xi'an City, and is of great significance to the health risk research of related populations.

Spatio-temporal characteristics of the relationship between carbon emissions and economic growth in China's transportation industry.

The economic and social development of a country rely heavily on transportation. In China, it has become the third largest energy consumption sector and generates substantial amounts of carbon emissions. In the present study, direct and indirect carbon emissions from the transportation industry throughout China's 30 provinces during 1997-2017 were calculated. Further, to reveal the spatio-temporal characteristics of the relationship between carbon emissions and economic growth, the standard deviational ellipse and Tapio decoupling method were employed. The main results are as follows. (1) The total carbon emissions from the transportation industry increased from 132.79 million tons (Mt) in 1997 to 849.64 Mt in 2017, with an average annual growth rate of 9.72%; direct carbon emissions accounted for approximately 86% of the total. (2) Carbon emissions as well as the added value of the transportation industry had the same spatial distribution characteristics, presenting a northeast-southwest pattern during 1997-2017. Although their spatial distribution patterns were mainly in the north-south direction, the development in the east-west direction became increasingly obvious. (3) The decoupling index in the transportation industry was greater than 0.8 for most years, with an expansive negative decoupling state or an expansive coupling state. The differences in carbon emissions and economic growth between various provinces showed a spatio-temporal disparity of the decoupling states in the transportation industry. The obtained results are of considerable interest for China's policymakers to set more reasonable carbon emission reduction goals and implement targeted policies according to the carbon emission situation at a local scale.

METS-IR, a novel simple insulin resistance indexes, is associated with hypertension in normal-weight Chinese adults.

Insulin resistance (IR) plays a crucial role in the development of hypertension, so early recognition of IR is of substantial clinical importance for the management of hypertension. But traditional IR indexes are invasive, complex, and impractical. We aimed to evaluate the associations between three simple IR indexes and hypertension in different body mass index (BMI) categories. A total of 142 005 adults who did not take antihypertensive medication were included in this analysis. The ratio of triglycerides to high-density lipoprotein cholesterol (TG/HDLc), the product of fasting triglycerides and glucose (TyG), and metabolic score for IR (METS-IR) were calculated according to the corresponding formulas. The associations between them and hypertension were analyzed by logistic regression. Among the three indicators, only METS-IR had positive correlations with blood pressure levels (all P < 0.001). After full adjustment, METS-IR was significantly associated with hypertension in the normal BMI group but not in the elevated BMI group. The OR for hypertension in the normal BMI group in the highest quartile of METS-IR was 2.884 (95% CI: 2.468-3.369) in the total sample, 1.915 (95% CI: 1.614-2.271) in females and 2.083 (95% CI: 1.717-2.527) in males. Our findings indicate that METS-IR, a simple and cost-effective IR index, was strongly associated with hypertension in normal-weight Chinese subjects. It could help monitor and manage hypertension in normal-weight individuals.

Exploring regional differences in the impact of high energy-intensive industries on CO2 emissions: Evidence from a panel analysis in China.

China is currently the largest CO2 emitter in the world. Within China, more than 60% of CO2 emissions originate from high energy-intensive (HEI) industries. Therefore, controlling and reducing CO2 emissions from HEI industries is crucial if China is to achieve its 2030 emission reduction targets. This study aims to investigate regional differences in the impact of HEI industries on CO2 emissions in China. This paper presents an analysis of the impact of HEI industries on CO2 emissions at the national and regional levels using a modified STIRPAT model and provincial panel data from 2000 to 2015 in China. The results show that HEI industries are significant contributors to China's CO2 emissions owing to the growth in industries, coal-based energy structure, low level of technology, and outstanding conduction effects. The impact intensity of HEI industries on CO2 emissions decreases from the western to the central and eastern regions in China because of a huge regional difference in industrial structure, energy structure, R&D investment, and industrial transfer. Our findings have important implications for policymakers in China by indicating that regional policies concerning HEI industries should be differentiated to successfully reduce CO2 emissions and meet national targets.

Association of Three Simple Insulin Resistance Indexes with Prehypertension in Normoglycemic Subjects.

Background: Insulin resistance (IR) is the common pathophysiology of prehypertension and prediabetes. Recognition of IR in one of the two disease states is critical for carrying out preventive strategies of another disease state. This study aimed to explore which simple IR indexes were significantly associated with prehypertension in subjects with normoglycemia. Methods: A total of 108,370 adults without elevated fasting plasma glucose and hypertension were included in this study. The three simple IR indexes [triglycerides to high-density lipoprotein cholesterol ratio, the product of fasting triglycerides and glucose, and metabolic score for IR (METS-IR)] were calculated. Partial correlation was used to analyze the correlation between the three indicators and blood pressure (BP) levels, and logistic regression analysis was used to explore their association with prehypertension. Results: Among the three indicators, only METS-IR had positive correlations with systolic and diastolic blood pressure levels. Furthermore, METS-IR was also significantly associated with prehypertension, irrespective of the categorization of waist circumference (WC). The odds ratios of the highest quartile were 2.223 (95% confidence interval [CI]: 2.044-2.417) in all subjects, 2.022 (95% CI: 1.501-2.725) in elevated WC subgroup, and 1.815 (95% CI: 1.620-2.034) in normal WC subgroup. Conclusions: METS-IR was associated with prehypertension in normoglycemic Chinese subjects, which bypasses the impact of WC and might be valuable for the management of prehypertension and the prevention of prediabetes in different ethnic groups.

Development and evaluation of a training model for paracentetic suprapubic cystostomy and catheterization.

OBJECTIVES: Minimally invasive paracentetic suprapubic cystostomy is a technique that should be learned by all surgical trainees and residents. This study aimed to develop a self-made training model for paracentetic suprapubic cystostomy and placement of the suprapubic catheter and then to evaluate its effectiveness in training fourth-year medical students. METHODS: Medical students were divided into an experimental group receiving comprehensive training involving literature, video, and model use and a control group receiving all the same training protocols as the experimental group except without hands-on practice using the model. Each student's performance was video-recorded, followed by subjective and objective evaluations by urology experts and statistical analysis. RESULTS: All students completed the surgical procedures successfully. The experimental group's performance scores were significantly higher than those of the control group (median final performance scores of 91.0 vs. 86.8, respectively). Excellent scores were achieved by more students in the experimental group than in the control group (55% vs. 20%), and fewer poor scores were observed in the experimental group than in the control group (5% vs. 30%). CONCLUSIONS: Based on its cost-effectiveness, reusability, and training effectiveness, this paracentetic suprapubic cystostomy training model is able to achieve goals in teaching practice quickly and easily. Use of the model should be encouraged for training senior medical students and resident physicians who may be expected to perform emergent suprapubic catheter insertion at some time.

The impacts of urbanization on fine particulate matter (PM2.5) concentrations: Empirical evidence from 135 countries worldwide.

Few attempts have been made to systematically investigate the impacts of urbanization on PM2.5 concentrations in countries at different stages of economic development. In this study, a broad concept of urbanization that considers the transformations in the urban economy and the transport sector induced by urbanization is proposed to investigate the influence of urbanization on national PM2.5 concentrations for underdeveloped, developing and developed countries during 1998-2014. The results indicate that urbanization has a significant relationship with PM2.5 concentrations, but the magnitude of its influence varies among groups of countries with different development levels. First, the positive response of PM2.5 concentrations to increased urbanization and transport-related emissions in underdeveloped countries are noticeably stronger than that in developing and developed countries. Second, for developing countries, urbanization, transport-related emissions and industrialization all have a significant positive effect on national PM2.5 concentrations increase, although their impacts are unexpectedly smaller than those in the other groups of countries. Finally, increasing urbanization and the decrease in CO2 emissions from manufacturing industry appear to reduce national average PM2.5 concentrations in developed countries, while the decrease in transport-related CO2 emission is likely to cause the rise in national average PM2.5 concentrations.

Development and evaluation of a training model for paracentetic suprapubic cystostomy and catheterization

OBJECTIVES: Minimally invasive paracentetic suprapubic cystostomy is a technique that should be learned by all surgical trainees and residents. This study aimed to develop a self-made training model for paracentetic suprapubic cystostomy and placement of the suprapubic catheter and then to evaluate its effectiveness in training fourth-year medical students. METHODS: Medical students were divided into an experimental group receiving comprehensive training involving literature, video, and model use and a control group receiving all the same training protocols as the experimental group except without hands-on practice using the model. Each student's performance was video-recorded, followed by subjective and objective evaluations by urology experts and statistical analysis. RESULTS: All students completed the surgical procedures successfully. The experimental group's performance scores were significantly higher than those of the control group (median final performance scores of 91.0 vs. 86.8, respectively). Excellent scores were achieved by more students in the experimental group than in the control group (55% vs. 20%), and fewer poor scores were observed in the experimental group than in the control group (5% vs. 30%). CONCLUSIONS: Based on its cost-effectiveness, reusability, and training effectiveness, this paracentetic suprapubic cystostomy training model is able to achieve goals in teaching practice quickly and easily. Use of the model should be encouraged for training senior medical students and resident physicians who may be expected to perform emergent suprapubic catheter insertion at some time.

An initial exploration for comprehensive assessment of IgG4-related lung disease: analyses on the cases enrolled from a systematic review.

BACKGROUND: The existence of two diagnostic systems, the Boston and Japan criteria, for immunoglobulin G4-related disease (IgG4-RD) confuse the medical practice. We aimed to develop a comprehensive assessment based on the weight of each diagnostic item in the existing criteria to improve the diagnostic efficiency of Boston criteria. METHODS: We assessed the patients enrolled by a systematic review of the literatures using the Boston criteria, Japan criteria and a tentative comprehensive assessment respectively, and evaluated the efficiency of each system and their consistency. RESULTS: Our analysis showed that the distinction in pathological diagnostic items was similar for the Boston criteria (IgG4+/IgG+ ratio, P<0.01; the number of pathological features and IgG4+ count, P<0.001) and comprehensive assessment (IgG4+/IgG+ ratio and the number of pathological features, P<0.001; IgG4+ count, P<0.05). For the Japan criteria, a good distinction in the number of pathological features was demonstrated (P<0.05) but the difference in the IgG4+/IgG+ ratio and IgG4+ count was not significant. There was relatively poor consistency between the Boston and Japan criteria (Kappa =0.482, P<0.001), while there was good agreement (Kappa =0.811, P<0.001), but a significant difference (P=0.011, McNemar matching test), between the Boston criteria and comprehensive assessment. CONCLUSIONS: The current two diagnostic systems have poor consistency. Comprehensive assessment has good agreement with the Boston criteria, but can identify those cases in Boston Category 3 who could still be diagnosed as IgG4-related lung disease. Considering the weight of diagnostic items, the scoring system is a tentative exploration that should be improved with further experience in diagnosing IgG4-related lung disease.