Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 15 de 15
Filtrar
Mais filtros

Bases de dados
País/Região como assunto
Tipo de documento
País de afiliação
Intervalo de ano de publicação
1.
BMJ Open ; 12(11): e062115, 2022 11 16.
Artigo em Inglês | MEDLINE | ID: mdl-36385039

RESUMO

OBJECTIVES: To study the overall disease prevalence, and associations between demographic, socioeconomic, psychosocial, and health-related factors, and self-reporting one or more long-term health conditions (LTCs) in a working-age inner-city population. DESIGN: Cross-sectional household-based survey with a follow-up timepoint. SETTING: South-East London Community Health survey data. PARTICIPANTS: 893 adults aged 16-64 years living in Lambeth and Southwark, London. OUTCOME MEASURES: Prevalence estimates of individual and multiple LTCs. Multinomial logistic regression was used to analyse the association of demographic, socioeconomic, psychosocial and health-related indicators with having one and multiple LTCs at two timepoints. RESULTS: More than one third of participants reported at least one LTC, with the most prevalent being musculoskeletal conditions and asthma. The prevalence of one LTC at both timepoints was 20.6% and 21.4%, and of multimorbidity was 14.0% and 16.4%. At both timepoints, the 35-44 age group showed the largest increase in prevalence of one LTC compared with the preceding age group (16-34). After adjusting for age and gender, small social networks and a larger number of stressful life events were associated with increased risk of having both one and multiple LTCs. The risk of multimorbidity was greater than for initial LTCs for small social networks (3.8 (95% CI: 1.8 to 7.8) compared with 2.0 (95% CI: 1.0 to 3.9)), and three to five stressful life events (3.0 (95% CI: 1.7 to 5.3) compared with 1.5 (95% CI 1.0 to 2.2)). CONCLUSIONS: In this study, the prevalence of multimorbidity increased more than the prevalence of one LTC between the two timepoints, indicating a progression of the overall disease prevalence over time. The 35-44 age group showed the greatest increase in the number of initial LTCs which support health-promotion interventions targeting younger age groups. Focusing on increasing social support networks and treating the psychological impact of stressful life events may also be of benefit.


Assuntos
Multimorbidade , Características de Residência , Adulto , Humanos , Estudos Transversais , Fatores Socioeconômicos , Reino Unido/epidemiologia
2.
J Ment Health ; 31(6): 801-808, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30902023

RESUMO

BACKGROUND: Little is known about the economic impact of military mental health screening. AIMS: To investigate (a) whether post-deployment screening of military personnel affects use and cost of services and (b) the impact of psychiatric morbidity on costs. METHODS: Participants were recruited from UK Royal Marine and Army platoons and randomised to an intervention group (which received tailored advice predicated upon mental health status) or a control group (which received general advice following assessment of mental health status). The intervention costs were calculated while service use and associated costs were assessed at 12-month follow-up. RESULTS: Data were available for 6323 participants. Mean screening cost was £34. Service costs were slightly higher in the control group compared to the intervention group (£1197 vs. £1147) which was not statistically significant (bootstrapped 95%CI, -£363 to £434. In both groups, screening and control, costs were significantly higher for those who screened positive for mental health problems. CONCLUSIONS: Costs were not affected by screening. In countries that have already implemented post-deployment screening, the political cost of disinvestment needs careful consideration. Those who develop psychiatric morbidity have substantially higher care costs than those who do not.


Assuntos
Transtornos Mentais , Militares , Humanos , Militares/psicologia , Transtornos Mentais/diagnóstico , Reino Unido , Análise Custo-Benefício
4.
Drug Alcohol Depend ; 219: 108463, 2021 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-33421804

RESUMO

BACKGROUND: Alcohol use and mental health problems often co-occur, however, little is known about how this varies by type of mental health problem and to what extent associations are explained by socioeconomic status (SES). Our study examined the prevalence and associations of non-drinking, hazardous use, and harmful/probable dependence in individuals who do and do not meet criteria for different mental health problems and whether associations remained after adjustment for SES. METHODS: A secondary analysis of an English dataset, 2014 Adult Psychiatric Morbidity Survey (N = 7,218), was conducted. The Alcohol Use Disorder Identification Test was used to categorise participants as non-drinking, low risk, hazardous use and harmful/probable dependence. Mental health problems were screened using a range of validated tools. Multinomial logistic regression analyses were used to address study aims. RESULTS: The prevalence of non-drinking, hazardous and harmful/probable dependence was higher among those meeting criteria for a mental health problem. After adjustment for SES, non-drinking was most common in those meeting criteria for probable psychotic disorder (MOR = 3.42, 95 %CI = 1.74-6.70), hazardous use in those meeting criteria for anti-social personality disorder (MOR = 2.66, 95 %CI = 1.69-4.20) and harmful/probable dependence in those meeting criteria for borderline personality disorder (MOR = 9.77, 95 % CI = 4.81-19.84). CONCLUSIONS: There were marked increases in the odds of reporting both non-drinking and harmful drinking among those meeting criteria for a mental health problem, particularly more severe problems. Our findings indicate that the relationship between alcohol and mental health is more complex and comorbid alcohol and mental health problems should be treated in parallel with access to both services.


Assuntos
Consumo de Bebidas Alcoólicas/epidemiologia , Saúde Mental , Classe Social , Adolescente , Adulto , Alcoolismo/epidemiologia , Inglaterra/epidemiologia , Etanol , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Transtornos da Personalidade , Prevalência , Inquéritos e Questionários
5.
Occup Environ Med ; 78(9): 643-647, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-33483458

RESUMO

OBJECTIVES: While most UK military personnel transition successfully into civilian life, some experience unemployment and disability, which may be partly attributable to in-service factors. This study aims to determine the degree to which in-service mental health problems impact on postservice benefit claims. METHODS: Using data from a cohort of 5598 recent leavers from regular service in the UK Armed Forces linked with data from the Department for Work and Pensions, we assessed associations between in-service mental health and postservice benefit claims, and the population attributable fraction (PAF) of benefit claims related to in-service mental health. An analysis with postservice mental ill health as mediator was performed to determine the degree to which the observed effects were a consequence of persistent illness, as opposed to remitted. RESULTS: Mental illness occurring in-service predicted both unemployment and disability claims, partly mediated by postservice health (23%-52% total effects mediated), but alcohol misuse did not. Common mental disorder (CMD) (PAF 0.07, 95% CI: 0.02 to 0.11) and probable post-traumatic stress disorder (PTSD) (PAF 0.05, 95% CI 0.01 to 0.09) contributed to unemployment claims. Probable PTSD was the largest contributor to disability claims (PAF 0.25, 95% CI 0.13 to 0.36), with a smaller contribution from CMD (PAF 0.16, 95% CI 0.03 to 0.27). CONCLUSIONS: In-service mental ill health gives rise to benefit claims. These effects are only partly mediated by postservice mental health, implying that in-service (or pre-service) mental issues have carry-over effects into civilian life even if remitted. Better prevention and treatment of in-service PTSD symptoms may well reduce postservice disability claims.


Assuntos
Transtornos Mentais/epidemiologia , Militares/psicologia , Ajuda a Veteranos de Guerra com Deficiência/estatística & dados numéricos , Humanos , Masculino , Militares/estatística & dados numéricos , Transtornos de Estresse Pós-Traumáticos/epidemiologia , Desemprego/psicologia , Desemprego/estatística & dados numéricos , Reino Unido/epidemiologia
6.
Psychol Med ; 51(2): 236-243, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-31779726

RESUMO

BACKGROUND: A proportion of ex-military personnel who develop mental health and social problems end up in the Criminal Justice System. A government review called for better understanding of pathways to offending among ex-military personnel to improve services and reduce reoffending. We utilised data linkage with criminal records to examine the patterns of offending among military personnel after they leave service and the associated risk (including mental health and alcohol problems) and socio-economic protective factors. METHOD: Questionnaire data from a cohort study of 13 856 randomly selected UK military personnel were linked with national criminal records to examine changes in the rates of offending after leaving service. RESULTS: All types of offending increased after leaving service, with violent offending being the most prevalent. Offending was predicted by mental health and alcohol problems: probable PTSD, symptoms of common mental disorder and aggressive behaviour (verbal, property and threatened or actual physical aggression). Reduced risk of offending was associated with post-service socio-economic factors: absence of debt, stable housing and relationship satisfaction. These factors were associated with a reduced risk of offending in the presence of mental health risk factors. CONCLUSIONS: Ex-military personnel are more likely to commit violent offences after leaving service than other offence-types. Mental health and alcohol problems are associated with increased risk of post-service offending, and socio-economic stability is associated with reduced risk of offending among military veterans with these problems. Efforts to reduce post-service offending should encompass management of socio-economic risk factors as well as mental health.


Assuntos
Criminosos/estatística & dados numéricos , Militares/estatística & dados numéricos , Veteranos/estatística & dados numéricos , Adulto , Campanha Afegã de 2001- , Agressão , Transtornos Relacionados ao Uso de Álcool/epidemiologia , Estudos de Coortes , Feminino , Humanos , Armazenamento e Recuperação da Informação , Guerra do Iraque 2003-2011 , Masculino , Saúde Mental , Pessoa de Meia-Idade , Fatores de Proteção , Fatores de Risco , Fatores Socioeconômicos , Transtornos de Estresse Pós-Traumáticos/epidemiologia , Inquéritos e Questionários , Reino Unido/epidemiologia
7.
BMC Psychiatry ; 16: 20, 2016 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-26830818

RESUMO

BACKGROUND: Research on trauma and its impact on mental health typically relies on self-reports which can be influenced by recall bias and an individual's subjective interpretation of events. This study aims to compare responses on a checklist of life events with a trauma experience screening question, both of which assessed trauma experience retrospectively. METHODS: A community sample of adults were asked about life events from a checklist before asking them whether they ever had a trauma experience, i.e. "an event that either puts them or someone close to them at risk of serious harm or death". RESULTS: Less than half of the sample who reported at least one life event on the checklist that qualified as a trauma reported a trauma experience that they perceived put them or close others at risk of serious harm. Women responders, those reporting early life traumas, and a greater number of lifetime trauma events were more likely to report a trauma experience. Current symptoms of Common Mental Disorder did not account for differences in reporting of trauma experiences. CONCLUSIONS: Epidemiological approaches which require participants to make subjective judgement on the severity of the trauma experience will capture individual differences that we have shown are influenced by gender and previous trauma experience.


Assuntos
Lista de Checagem , Acontecimentos que Mudam a Vida , Rememoração Mental , Ferimentos e Lesões/diagnóstico , Ferimentos e Lesões/epidemiologia , Adolescente , Adulto , Feminino , Humanos , Londres/epidemiologia , Masculino , Transtornos Mentais/diagnóstico , Transtornos Mentais/epidemiologia , Pessoa de Meia-Idade , Prevalência , Estudos Retrospectivos , Autorrelato , Adulto Jovem
8.
BMC Public Health ; 12: 797, 2012 Sep 17.
Artigo em Inglês | MEDLINE | ID: mdl-22985427

RESUMO

BACKGROUND: There is no doubt that the perceived stigma of having a mental disorder acts as a barrier to help seeking. It is possible that personnel may be reluctant to admit to symptoms suggestive of poor mental health when such data can be linked to them, even if their personal details are only used to help them access further care. This may be particularly relevant because individuals who have a mental health problem are more likely to experience barriers to care and hold stigmatizing beliefs. If that is the case, then mental health screening programmers may not be effective in detecting those most in need of care. We aimed to compare mental health symptom reporting when using an anonymous versus identifiable questionnaire among UK military personnel on deployment in Iraq. METHODS: Survey among UK military personnel using two questionnaires, one was anonymous (n = 315) and one collected contact details (i.e. identifiable, n = 296). Distribution was by alternate allocation. Data were collected in Iraq during January-February 2009. RESULTS: No significant difference in the reporting of symptoms of common mental disorders was found (18.1% of identifiable vs. 22.9% of anonymous participants). UK military personnel were more likely to report sub-threshold and probable PTSD when completing questionnaires anonymously (sub-threshold PTSD: 2.4% of identifiable vs. 5.8% of anonymous participants; probable PTSD: 1.7% of identifiable vs. 4.8% of anonymous participants). Of the 11 barriers to care and perceived social stigma statements considered, those completing the anonymous questionnaire compared to those completing the identifiable questionnaire were more likely to endorse three statements: "leaders discourage the use of mental health services" (9.3% vs. 4.6%), "it would be too embarrassing" (41.6% vs. 32.5%) and "I would be seen as weak" (46.6% vs. 34.2%). CONCLUSIONS: We found a significant effect on the reporting of sub-threshold and probable PTSD and certain stigmatizing beliefs (but not common mental disorders) when using an anonymous compared to identifiable questionnaire, with the anonymous questionnaire resulting in a higher prevalence of PTSD and increased reporting of three stigmatizing beliefs. This has implications for the conduct of mental health screening and research in the US and UK military.


Assuntos
Atitude Frente a Saúde , Confidencialidade , Transtornos Mentais/psicologia , Militares/psicologia , Inquéritos e Questionários , Adulto , Feminino , Acessibilidade aos Serviços de Saúde , Humanos , Guerra do Iraque 2003-2011 , Masculino , Serviços de Saúde Mental/estatística & dados numéricos , Militares/estatística & dados numéricos , Estigma Social , Transtornos de Estresse Pós-Traumáticos/psicologia , Reino Unido
9.
Br J Psychiatry ; 201(3): 193-8, 2012 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-22539778

RESUMO

BACKGROUND: Most studies of the mental health of UK armed forces focus on retrospective accounts of deployment and few sample personnel while they are deployed. AIMS: This study reports the results of a survey of deployed personnel, examining the perceived impact of events at home and military support for the family on current mental health during the deployment. METHOD: Surveys were conducted with 2042 British forces personnel serving in Iraq and Afghanistan. Prevalence of common mental disorders was assessed with the 12-item General Health Questionnaire (GHQ-12) and post-traumatic stress disorder (PTSD) was assessed with the PTSD Checklist - Civilian version (PCL-C). RESULTS: The prevalence of common mental disorders was 17.8% and of probable PTSD was 2.8%. Perceived home difficulties significantly influenced the mental health of deployed personnel; the greater the perception of negative events in the home environment, the greater the reporting of adverse mental health effects. This finding was independent of combat exposure and was only partially mitigated by being well led and reporting subjectively good unit cohesion; however, the effect of the totality of home-front events was not improved by the latter. Poor perceived military support for the family had a detrimental impact on deployment mental health. CONCLUSIONS: The armed forces offer many support services to the partners and families of deployed personnel and ensuring that the efforts being made on their behalf are well communicated might improve the mental health of deployed personnel.


Assuntos
Família/psicologia , Transtornos Mentais/psicologia , Saúde Mental , Militares/psicologia , Percepção , Apoio Social , Campanha Afegã de 2001- , Distúrbios de Guerra/epidemiologia , Distúrbios de Guerra/psicologia , Apoio Financeiro , Financiamento Pessoal , Humanos , Relações Interpessoais , Transtornos Mentais/epidemiologia , Prevalência , Reino Unido/epidemiologia
10.
BMC Public Health ; 11: 861, 2011 Nov 11.
Artigo em Inglês | MEDLINE | ID: mdl-22078667

RESUMO

BACKGROUND: Responses to public health need require information on the distribution of mental and physical ill health by demographic and socioeconomic factors at the local community level. METHODS: The South East London Community Health (SELCoH) study is a community psychiatric and physical morbidity survey. Trained interviewers conducted face-to-face computer assisted interviews with 1698 adults aged 16 years and over, from 1076 randomly selected private households in two south London boroughs. We compared the prevalence of common mental disorders, hazardous alcohol use, long standing illness and general physical health by demographic and socioeconomic indicators. Unadjusted and models adjusted for demographic and socioeconomic indicators are presented for all logistic regression models. RESULTS: Of those in the sample, 24.2% reported common mental disorder and 44.9% reported having a long standing illness, with 15.7% reporting hazardous alcohol consumption and 19.2% rating their health as fair or poor. The pattern of indicators identifying health inequalities for common mental disorder, poor general health and having a long term illness is similar; individuals who are socioeconomically disadvantaged have poorer health and physical health worsens as age increases for all groups. The prevalence of poor health outcomes by ethnic group suggests that there are important differences between groups, particularly for common mental disorder and poor general health. Higher socioeconomic status was protective for common mental disorder, fair or poor health and long standing illness, but those with higher socioeconomic status reported higher levels of hazardous alcohol use. The proportion of participants who met the criteria for common mental disorder with co-occurring functional limitations was similar or greater to those with poor physical health. CONCLUSIONS: Health service providers and policy makers should prioritise high risk, socially defined groups in combating inequalities in individual and co-occurring poor mental and physical problems. In population terms, poor mental health has a similar or greater burden on functional impairment than long term conditions and perceived health.


Assuntos
Demografia , Disparidades nos Níveis de Saúde , Classe Social , Adolescente , Adulto , Idoso , Feminino , Comportamentos Relacionados com a Saúde , Indicadores Básicos de Saúde , Humanos , Entrevistas como Assunto , Londres/epidemiologia , Masculino , Pessoa de Meia-Idade , Razão de Chances , Adulto Jovem
11.
Int Rev Psychiatry ; 23(2): 153-9, 2011 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-21521084

RESUMO

Concerns about the mental health of military personnel deployed to Iraq and Afghanistan has led to a new generation of research. This review is an examination of the UK literature on the mental health consequences of deployment of armed forces personnel to Iraq and Afghanistan. As yet, deployment to Iraq or Afghanistan has not been associated with a general increase in mental health problems for the UK Armed Forces. However, research has highlighted certain problems that continue to need to be addressed. Whilst, the rate of post-traumatic stress disorder (PTSD) is low in the UK Armed Forces (1.6-6%), deployment to Iraq or Afghanistan is associated with an increased risk of PTSD for reserve personnel. In contrast to PTSD, the rate of alcohol misuse is high in the UK Armed Forces (between 16-20%), and has been associated with deployment to Iraq or Afghanistan for regular personnel. As the UK military engagement in Afghanistan continues and more personnel are deployed, the demand for help from military health services, the NHS and the service charities will increase.


Assuntos
Conflito Psicológico , Serviços de Saúde Mental/tendências , Saúde Mental , Militares/psicologia , Campanha Afegã de 2001- , Alcoolismo/etiologia , Alcoolismo/psicologia , Alcoolismo/reabilitação , Necessidades e Demandas de Serviços de Saúde/tendências , Humanos , Guerra do Iraque 2003-2011 , Fatores de Risco , Transtornos de Estresse Pós-Traumáticos/etiologia , Transtornos de Estresse Pós-Traumáticos/psicologia , Transtornos de Estresse Pós-Traumáticos/reabilitação , Reino Unido
12.
BMC Health Serv Res ; 11: 31, 2011 Feb 10.
Artigo em Inglês | MEDLINE | ID: mdl-21310027

RESUMO

BACKGROUND: As with the general population, a proportion of military personnel with mental health problems do not seek help. As the military is a profession at high risk of occupational psychiatric injury, understanding barriers to help-seeking is a priority. METHOD: Participants were drawn from a large UK military health study. Participants undertook a telephone interview including the Patient Health Questionnaire (PHQ); a short measure of PTSD (Primary Care PTSD, PC-PTSD); a series of questions about service utilisation; and barriers to care. The response rate was 76% (821 participants). RESULTS: The most common barriers to care reported are those relating to the anticipated public stigma associated with consulting for a mental health problem. In addition, participants reported barriers in the practicalities of consulting such as scheduling an appointment and having time off for treatment. Barriers to care did not appear to be diminished after people leave the Armed Forces. Veterans report additional barriers to care of not knowing where to find help and a concern that their employer would blame them for their problems. Those with mental health problems, such as PTSD, report significantly more barriers to care than those who do not have a diagnosis of a mental disorder. CONCLUSIONS: Despite recent efforts to de-stigmatise mental disorders in the military, anticipated stigma and practical barriers to consulting stand in the way of access to care for some Service personnel. Further interventions to reduce stigma and ensuring that Service personnel have access to high quality confidential assessment and treatment remain priorities for the UK Armed Forces.


Assuntos
Acessibilidade aos Serviços de Saúde , Transtornos Mentais/epidemiologia , Preconceito , Veteranos/psicologia , Intervalos de Confiança , Estudos Transversais , Humanos , Entrevistas como Assunto , Transtornos Mentais/terapia , Serviços de Saúde Mental/estatística & dados numéricos , Inquéritos e Questionários , Reino Unido/epidemiologia
13.
J Trauma Stress ; 23(4): 430-6, 2010 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-20690168

RESUMO

Trauma Risk Management is a peer-support program that aims to promote help-seeking in the aftermath of traumatic events. Prior to its implementation, the British military conducted a randomized controlled trial of Trauma Risk Management against standard care in 12 warships; 6 were randomized to use Trauma Risk Management after collecting baseline measurements. Follow up after 12-18 months found no significant change in psychological health or stigma scores in either group; however, the studied vessels only encountered low numbers of critical incidents. Additionally, measurements of organizational functioning were modestly better in the Trauma Risk Management ships. The authors conclude that within organizations using Trauma Risk Management may be beneficial and may, in time, lead to a valuable cultural shift.


Assuntos
Distúrbios de Guerra/terapia , Militares/psicologia , Medicina Naval , Grupo Associado , Gestão de Riscos/organização & administração , Apoio Social , Transtornos de Estresse Pós-Traumáticos/terapia , Adulto , Análise por Conglomerados , Distúrbios de Guerra/diagnóstico , Distúrbios de Guerra/psicologia , Feminino , Seguimentos , Humanos , Masculino , Aceitação pelo Paciente de Cuidados de Saúde/psicologia , Preconceito , Medição de Risco , Transtornos de Estresse Pós-Traumáticos/diagnóstico , Transtornos de Estresse Pós-Traumáticos/psicologia , Reino Unido , Adulto Jovem
14.
Eur J Public Health ; 18(4): 422-7, 2008 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-18467359

RESUMO

AIM: There is evidence of increased health care utilization by medical personnel (medics) compared to other trades in the UK Armed Forces. The aim of this study was to compare the burden of mental ill health in deployed medics with all other trades during the Iraq war. METHODS: Participants' main duty during deployment was identified from responses to a questionnaire and verified from Service databases. Psychological health outcomes included psychological distress, post-traumatic stress disorder, multiple physical symptoms, fatigue and heavy drinking. RESULTS: A total of 479 out of 5824 participants had a medical role. Medics were more likely to report psychological distress (OR 1.30, 95% CI 1.00-1.70), multiple physical symptoms (OR 1.65, 95% CI 1.20-2.27) and, if men, fatigue (1.38, 95% CI 1.05-1.81) than other personnel. Female medics were less likely to report fatigue (0.57 95% CI 0.35-0.92). Neither post-traumatic stress disorder nor heavy drinking symptoms were associated with a medical role. Traumatic medical experiences, lower group cohesion and preparedness, and post-deployment experiences explained the positive associations with psychological ill health. Medics made greater use of medical facilities than other trades. CONCLUSIONS: There is a small excess of psychological ill health in medics, which can be explained by poorer group cohesion, traumatic medical and post-deployment experiences. The association of mental ill health with a medical role was not the consequence of a larger proportion of reservists in this group.


Assuntos
Pessoal de Saúde/psicologia , Saúde Mental , Militares/psicologia , Adulto , Alcoolismo/epidemiologia , Feminino , Humanos , Guerra do Iraque 2003-2011 , Liderança , Masculino , Fatores Sexuais , Fatores Socioeconômicos , Transtornos de Estresse Pós-Traumáticos/epidemiologia , Estresse Psicológico/epidemiologia , Reino Unido
15.
Int J Epidemiol ; 35(6): 1504-13, 2006 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-16945940

RESUMO

BACKGROUND: It is widely believed that children of high socioeconomic status (SES) are more likely than those of low SES to develop acute lymphoblastic leukaemia (ALL). Such observations have led to wide-ranging speculations about the potential aetiological role of factors associated with affluence and modernization. METHODS: Children (0-14 years) newly diagnosed with cancer in the UK between 1991 and 1996 were ascertained via a rapid hospital-based case finding system (n = 4430, of which 1578 were ALL). Children without cancer (controls) were randomly selected from primary care population registries for comparative purposes (n = 7763). Area-based deprivation scores were assigned as markers of SES at two time points - birth and diagnosis. An individual-based marker of SES - social class - was assigned using father's occupation as recorded on the child's birth certificate. RESULTS: No differences in area-based measures of deprivation were observed between cases and controls at time of diagnosis, either for all cancers combined [n = 4430, odds ratio (OR) = 1.00 (95% confidence intervals (CI) 0.98-1.01)] or for ALL alone (n = 1578 OR = 0.99, 95%CI 0.96-1.01). Findings were similar at time of birth (all cancers, OR = 0.99 95%CI 0.98-1.01, ALL OR = 0.98, 95%CI 0.96-1.00). In addition, no case-control differences were observed when an individual-based measure of SES - social class - based on father's occupation at time of birth was used. CONCLUSIONS: The comprehensive nature of the data, coupled with complete case-ascertainment and representative population-based controls suggests that SES in the UK is not a determinant of ALL in children. We believe the small effects reported for SES in some past studies may be artefactual.


Assuntos
Leucemia-Linfoma Linfoblástico de Células Precursoras/epidemiologia , Fatores Socioeconômicos , Adolescente , Viés , Estudos de Casos e Controles , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Leucemia/epidemiologia , Masculino , Carência Psicossocial , Fatores de Risco , Classe Social , Mobilidade Social , Reino Unido/epidemiologia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA