A computational framework for transmission risk assessment of aerosolized particles in classrooms.

Infectious airborne diseases like the recent COVID-19 pandemic render confined spaces high-risk areas. However, in-person activities like teaching in classroom settings and government services are often expected to continue or restart quickly. It becomes important to evaluate the risk of airborne disease transmission while accounting for the physical presence of humans, furniture, and electronic equipment, as well as ventilation. Here, we present a computational framework and study based on detailed flow physics simulations that allow straightforward evaluation of various seating and operating scenarios to identify risk factors and assess the effectiveness of various mitigation strategies. These scenarios include seating arrangement changes, presence/absence of computer screens, ventilation rate changes, and presence/absence of mask-wearing. This approach democratizes risk assessment by automating a key bottleneck in simulation-based analysis-creating an adequately refined mesh around multiple complex geometries. Not surprisingly, we find that wearing masks (with at least 74% inward protection efficiency) significantly reduced transmission risk against unmasked and infected individuals. While the use of face masks is known to reduce the risk of transmission, we perform a systematic computational study of the transmission risk due to variations in room occupancy, seating layout and air change rates. In addition, our findings on the efficacy of face masks further support use of face masks. The availability of such an analysis approach will allow education administrators, government officials (courthouses, police stations), and hospital administrators to make informed decisions on seating arrangements and operating procedures. Supplementary Information: The online version contains supplementary material available at 10.1007/s00366-022-01773-9.

Constructing Markov matrices for real-time transient contaminant transport analysis for indoor environments.

Predicting the movement of contaminants in the indoor environment has applications in tracking airborne infectious disease, ventilation of gaseous contaminants, and the isolation of spaces during biological attacks. Markov matrices provide a convenient way to perform contaminant transport analysis. However, no standardized method exists for calculating these matrices. A methodology based on set theory is developed for calculating contaminant transport in real-time utilizing Markov matrices from CFD flow data (or discrete flow field data). The methodology provides a rigorous yet simple strategy for determining the number and size of the Markov states, the time step associated with the Markov matrix, and calculation of individual entries of the Markov matrix. The procedure is benchmarked against scalar transport of validated airflow fields in enclosed and ventilated spaces. The approach can be applied to any general airflow field, and is shown to calculate contaminant transport over 3000 times faster than solving the corresponding scalar transport partial differential equation. This near real-time methodology allows for the development of more robust sensing and control procedures of critical care environments (clean rooms and hospital wards), small enclosed spaces (like airplane cabins) and high traffic public areas (train stations and airports).