Soil pollution indices and health risk assessment of metal(loid)s in the agricultural soil of pistachio orchards.

Elevated levels of metal(loid)s in soil may pose potential threats to the ecosystem and can be harmful for human health. The concentrations of As, Cd, Pb, Cr and Ni were determined in agricultural soil collected from 45 pistachio orchards around Feizabad city, Khorasan Razavi province, Iran using ICP-OES. Also, soil pollution indices including contamination factor (CF), pollution load index (PLI) and geo-accumulation index (Igeo) were evaluated. In addition, non-carcinogenic and carcinogenic risk indices were estimated. The mean concentrations of metal(loid)s were in the order of Ni = 466.256 > Cr = 120.848 > Pb = 12.009 > As = 5.486 > Cd = 0.394 mg/kg. Concentrations of As, Cd and Pb in the soil samples were within their respective permissible limits set by World Health Organization (WHO). But concentrations of Cr and Ni in 84.4 and 100% of the samples, respectively exceeded the WHO allowable limits. The CF, PLI and Igeo showed that soil of some of the pistachio orchards was contaminated with some metals. The possible sources of the metals in the soil are application of pesticides, chemical fertilizers, manures as well as irrigation water. Hazard quotient (HQ) ad Hazard index (HI) values from soil of all the orchards were found to be well below the respective threshold limit (1), suggesting that there is no immediate non-cancer threat arising from the contamination at all the orchards with metal(loid)s for children and adults. The highest cancer risk values (1.13E-02 for children and 1.25E-03 for adults) were estimated for Ni in the soil. Collectively, this study provides valuable information to improve the soil in the pistachio orchards to reduce metal(loid)s contamination and minimize the associated health risks to the population in the area.

Wastewater treatment plants: The missing link in global One-Health surveillance and management of antibiotic resistance.

INTRODUCTION: As a global public health crisis, antibiotic resistance (AR) should be monitored and managed under the One-Health concept according to the World Health Organization (WHO), considering the interconnection between humans, animals, and the environment. But this approach often remains focused on human health and rarely on the environment and its compartments, especially wastewater as the main AR receptor. Wastewater treatment plants (WWTPs) not only are not designed for reliving AR but also provide appropriate conditions for enhancing AR through different mechanisms. METHODS: By reviewing the research-based statistics on the inclusion of WWTPs in the One-Health/AR program crisis, this paper highlights the importance of paying attention to these hotspots, at first. Also, the importance and technical roadmap for the application of WWTPs in both surveillance and management of AR were provided. The current position of these facilities was also evaluated using strengths, weaknesses, opportunities, and threats (SWOT) analysis. In the end, the concluding knowledge gaps and research needs for future investigations were presented. RESULTS: Despite the fact that wastewater matrices are the hotspot for AR dissemination, WWTPs appear under-represented in One-Health/AR literature. So, of the 414434 articles retrieved for One-Health only 1.5% (n = 6321) focused on AR and about 0.04% (n = 158) on WWTPs. The potential of WWTPs inclusion in AR surveillance has been confirmed by several studies, however, when it comes to its inclusion for management of AR, more evidence should be presented, which confirmed by SWOT results. DISCUSSION: As such, WWTPs simultaneously provide opportunities for AR surveillance as it is assumed that this medium can reflect the reality of the corresponding society, and for managing unexpected crises which could impact the public. Nonetheless, there are still numerous considerations to change WWTPs role from Achilles' heel to Ajax' shield, including strengthening the research-based knowledge and conducting both surveillance and management strategies of AR under One-Health concept (One-Health/AR) in a clear straightforward framework.

Bioaccumulation and health risk assessment of exposure to potentially toxic elements by consuming agricultural products irrigated with wastewater effluents.

Potentially toxic elements (PTEs) have many adverse health effects due to bioaccumulation capability and their long persistence in the environment. As a renewable water source, the effluents of municipal wastewater treatment systems have been used to irrigate agricultural products widely. However, the evidence on the bioaccumulation of PTEs in crops irrigated with these effluents is still scarce, with no available study in low and middle-income countries. Therefore, this study aimed to assess the PTEs concentration in the soil and crops irrigated with effluents of Sabzevar wastewater treatment plant and the related health risk by that. The clustered method was used to determine the soil and craps samples. Seventy cumulative samples were randomly prepared in summer and autumn 2016 and 2017 from crops, soil and effluent. Inductively coupled plasma mass spectrometry (ICP-MS) was used to measure PTEs. The health risk of exposure to PTEs was assessed using Monte Carlo simulation technique. Kruskal Wallis test and Posthoc Tukey HSD test were used to assess the mean difference of PTEs between soil, effluent and crops as well as between crops together. The bioaccumulation factor (BAF) magnitude order in different crop samples was Cd > Sr > Cu > Pb > Zn > Co > As > Cr > Ni, respectively. The Cd accumulation in Sugar beet plant was significantly higher than in other samples. The highest hazard quotient (HQ) based on single PTEs was observed for As (mineral) (mean: 5.62 × 10-1 and percentile 95th: 2.13) in Okra. Regarding total HQ (THQ), the highest and lowest mean (percentile 95th) values were 1.50 (3.22) and 2.40 × 10-1 (4.01 × 10-1) for Okra and Watermelon, respectively. The mean concentrations of Co, Cr, Ni and Zn were significantly higher in crops compared to soil and influent samples. Posthoc tests indicated that the concentration of PTEs between investigated crop samples were not statistically significant different (p > 0.05). Overall, our study suggested that irrigation with the effluent of stabilization pond wastewater treatment system exerts a potential health risk due to bioaccumulation of PTEs in crops.

Concentration of potentially harmful elements (PHEs) in eggplant vegetable (Solanum melongena) irrigated with wastewater: a systematic review and meta-analysis and probabilistic health risk assessment.

The main objectives of this study were PHEs concentration meta-analysis (Fe, Zn, Cr, Ni, Cu, Pb, and Cd) in eggplant irrigated by wastewater and the following estimation of non-carcinogenic (n-CR) risk for the consumers based on countries. According to the results, the rank order of PHEs concentration in eggplant was Fe (88.3 mg/kg -dry weight) > Zn (10.1 mg/kg -dry weight) > Pb (3.0 mg/kg -dry weight) > Ni (2.7 mg/kg -dry weight) > Cu (1.1 mg/kg -dry weight) > Cd (0.9 mg/kg -dry weight) > Cr (0.05 mg/kg -dry weight). Moreover, n-CR risk showed that all investigated countries (China, India, Pakistan, Turkey, and Jordan) except for United Arab Emirates (UAE) had a considerable n-CR in both age groups (adults and children).

Potentially Toxic Elements (PTEs) in the Fillet of Narrow-Barred Spanish Mackerel (Scomberomorus commerson): a Global Systematic Review, Meta-analysis and Risk Assessment.

The contamination of seafood like narrow-barred Spanish mackerel (Scomberomorus commerson) fillets by potentially toxic elements (PTEs) has converted to worldwide health concerns. In this regard, the related citations regarding the concentration of PTEs in fillets of narrow-barred Spanish mackerel were collected through some of the international databases such as Scopus, Cochrane, PubMed, and Scientific Information Database (SID) up to 10 March 2020. The concentration of PTEs in fillets of narrow-barred Spanish mackerel fish was meta-analyzed and the health risk (non-carcinogenic risk) was estimated by the total target hazard quotient (TTHQ). The meta-analysis of data indicated that the rank order of PTEs in fillet of narrow-barred Spanish mackerel was Fe (10,853.29 µg/kg-ww) > Zn (4007.00 µg/kg-ww) > Cu (1005.66 µg/kg-ww) > total Cr (544.14 µg/kg-ww) > Mn (515.93 µg/kg-ww) > Ni (409.90 µg/kg-ww) > Pb (180.99 µg/kg-ww) > As (93.11 µg/kg-ww) > methyl Hg (66.60 µg/kg-ww) > Cd (66.03 µg/kg-ww). The rank order of health risk assessment based on the country by the aid of TTHQ for adult consumers was Malaysia (0.22251) > Philippines (0.21912) > Egypt (0.08684) > Taiwan (0.07430) > Bahrain (0.04893) > Iran (0.03528) > China (0.00620) > Pakistan (0.00316) > Yemen (0.00157) > India (0.00073). In addition, the rank order of health risk assessment based on the country by the aid of TTHQ for child consumers was Malaysia (1.03838) > Philippines (1.02257) > Egypt (0.40523) > Taiwan (0.34674) > Bahrain (0.22832) > Iran (0.16466) > China (0.02892) > Pakistan (0.01474) > Yemen (0.00731) > India (0.00340). Therefore, the children in Malaysia and the Philippines were at considerable non-carcinogenic risk. Hence, approaching the recommended control plans in order to decrease the non-carcinogenic risk associated with the ingestion of PTEs via the consumption of narrow-barred Spanish mackerel fish fillets is crucial.

Ecological and health risk assessment of exposure to atmospheric heavy metals.

In the present study, we assessed the concentration of airborne HMs (Zn, Cu, Pb, and Cd) and their probable sources using the bark of Pinus eldarica as a bio-indicator. Hence, 47 tree bark samples were harvested according to the land uses and biomonitoring techniques in the city of Yazd, Iran. The potential health risks in 13 age groups, ecological risk, as well as the possible relationship between HM concentrations and traffic indicators, were evaluated. The order of average HM concentrations in the P. eldarica bark samples was as Zn > Pb > Cu > Cd. The mean values of non-carcinogenic risks of all HMs in entire age groups were within secure range (HQ < 1); however, the carcinogenic risk of Cd was higher than the allowed level (TCR > 1 × 10-6). About Pb, it was in the safe level. The main element causing potential ecological risks was Cd, indicating moderate to very high ecological risk in most of the study areas. There was an inverse significant association between distance from major roads and Pb concentration (ß = -0.011 95% confidence interval (CI): 0.022, -0.0001). All HMs in bark samples render the negative Moran's index, representing a random spatial distribution pattern. Besides, according to principal component analysis (PCA), the first component accounted for 36.55% of the total variance, dominated by Cd, Pb, Cu, and Zn, respectively, and characterized by vehicle and industrial emissions. Our results infer that industrial activities and traffic are the main sources of HMs pollution in urban environments that should be considered by decision-makers.

Spatial variation and probabilistic risk assessment of exposure to fluoride in drinking water.

Assessing the health risks of exposure to fluoride in developing countries has been unclear. In this study, the concentration of fluoride and its spatial analysis in groundwater of 6 counties of Yazd province, Iran, were investigated. Health risk assessment of three age groups (children, teens and adults), sensitivity analysis and uncertainties of effective variables were carried out using Monte Carlo simulation. The results showed that 68.77% of the samples taken were within the standard range set by the WHO guidelines (0.5-1.5 mg/l). The mean (Standard division) of fluoride in Ardakan, Azezar, Mehriz, Meybod, Taft and Yazd were 0.83 (0.31), 0.73 (0.41), 0.56 (0.20), 0.91 (0.32), 0.60 (0.32) and 0.64 (0.25) respectively. Among the studied counties, Ashkezar has the highest dispersion in terms of high concentration of fluoride. The hazard quotient (HQ) value for all age groups except children was less than 1, indicated potential of non-cancer risk of exposure to fluoride for this group. The most important variable in calculating the HQ was the drinking water ingestion rate, concentration of fluoride and the fraction of skin in contact with water, so more focused on these parameters should be made for a more accurate health risk assessment.

Investigation of outdoor BTEX: Concentration, variations, sources, spatial distribution, and risk assessment.

The aim of this study was to measure BTEX (benzene, toluene, ethylbenzene, and xylenes) concentrations in the ambient air of Tehran, the capital of Iran, and investigate their seasonal variations, probable sources, spatial mapping, and risk assessment. The concentrations of BTEX were measured using a continuous monitoring device installed in seven stations around the city. Spatial mapping procedure was conducted using the inverse distance weighting (IDW) method. Monte Carlo simulation was used to assess the carcinogenic and noncarcinogenic risks imposed by BTEX. The highest and lowest annual mean concentrations of toluene and ethylbenzene were recorded as 16.25 and 3.63 µg m(-3), respectively. The maximum (6.434) and minimum (3.209) toluene/benzene (T/B) ratio was observed in summer and winter, respectively. The spatial distribution of BTEX pollution indicated that the highest concentrations were found along the major roads because of heavy traffic. Spearman's rank correlation coefficients and concentration ratios showed that BTEX were produced by the multiemission sources. The mean of inhalation lifetime cancer risk (LTCR) for benzene was 3.93 × 10(-7), which is lower than the limits recommended by the United States Environmental Protection Agency (US EPA) and the World Health Organization (WHO). The hazard quotient (HQ), noncarcinogenic risk index, for all BTEX compounds was <1. The obtained results showed no threat of BTEX concentrations to human health. However, as the concentrations of BTEX will increase due to the rapid growth of vehicles and industrial activities, much effort is required to control and manage the levels of these compounds in the future.