Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way.

The goal of head and neck oncological surgery is complete tumor resection with adequate resection margins while preserving acceptable function and appearance. For oral cavity squamous cell carcinoma (OCSCC), different studies showed that only 15%-26% of all resections are adequate. A major reason for the low number of adequate resections is the lack of information during surgery; the margin status is only available after the final histopathologic assessment, days after surgery. The surgeons and pathologists at the Erasmus MC University Medical Center in Rotterdam started the implementation of specimen-driven intraoperative assessment of resection margins (IOARM) in 2013, which became the standard of care in 2015. This method enables the surgeon to turn an inadequate resection into an adequate resection by performing an additional resection during the initial surgery. Intraoperative assessment is supported by a relocation method procedure that allows accurate identification of inadequate margins (found on the specimen) in the wound bed. The implementation of this protocol resulted in an improvement of adequate resections from 15%-40%. However, the specimen-driven IOARM is not widely adopted because grossing fresh tissue is counter-intuitive for pathologists. The fear exists that grossing fresh tissue will deteriorate the anatomical orientation, shape, and size of the specimen and therefore will affect the final histopathologic assessment. These possible negative effects are countered by the described protocol. Here, the protocol for specimen-driven IOARM is presented in detail, as performed at the institute.

Nursing issues in renal replacement therapy: organization, manpower assessment, competency evaluation and quality improvement processes.

For the patient with acute kidney injury, continuous renal replacement therapy (CRRT) is a treatment option that has application for the hemodynamically unstable critically ill patient. The decision to initiate a continuous renal replacement modality depends not only on the physician, either the nephrologist or intensivist, but also on the availability of specially trained nursing resources. This article will explore the nursing collaborative model of care at a large university-based research and teaching Medical Center in Southern California. The focus will be on nursing issues in CRRT including organization of educational programs, manpower assessment, competency evaluation, and quality improvement processes.

Real-time assessment of nurse work environment and stress.

Ecological momentary assessment methods were used to examine real-time relationships between work environment factors and stress in a sample of 119 registered nurses (RNs) in acute and critical care settings of three hospitals. The RNs carried handheld computers for 1 week of work shifts and were randomly surveyed within 90-min intervals to self-report work activity, perceived workload, and stress. Mixed effects linear regression analyses were completed to predict the stress score in the sample. The number of patients assigned significantly predicted stress; the greater the number of assigned patients, the higher the reported stress (p<.01). Age, gender, adult versus pediatric facility type, familiarity with patients, and proportion of direct care tasks were not significant predictors of stress. Further research is needed to link work environment factors and stress with errors among nurses.

A review of selected longitudinal studies on aging: past findings and future directions.

A review of the 51 longitudinal aging studies currently in the National Institute on Aging Database of Longitudinal Studies was conducted to identify major information gaps and areas for future research. Database information, which included posted study summaries, study details from principal investigators or directors of these projects, and more than 300 recent publications based on the studies, were reviewed to identify significant findings of each study. This review summarizes the main findings and identifies the need for future work within six broad study topics: cognitive function, socioeconomic status, health and physical performance, morbidity and mortality predictors, healthcare costs, and genetics. The percentages of these 51 studies addressing the four most common topics are as follows: cognitive function (44%), health and physical performance (51%), socioeconomic factors (55%), and predictors of morbidity/mortality (63%). Important areas not addressed to any major degree were healthcare costs and genetics. Only two studies reported findings on genetics or epigenetics of human aging, and only a single study reported on associations between aging and financial costs, especially healthcare costs, which have been postulated to be important determinants of care and life quality. The results of this review, together with the specific directions proposed by other investigators with longitudinal study expertise, will inform the strategic planning of future long-term studies of aging.

Critical care education: experience with a community-based consortium approach.

A continuous cycle of new orientees, cost-containment issues related to orientation, and conflicting job priorities prove to be challenging adversaries for critical care educators. The San Diego Chapter of the American Association of Critical Care Nurses (AACN) has met some of these educational challenges by providing a community-wide, consortium-based Critical Care Nursing Internship Program (CCIP) for novice critical care nurses. Over the last 15 years this CCIP has been instrumental in providing comprehensive education for more than 2,200 novice critical care nurses in San Diego County. This article discusses the background, rewards, and current challenges of the program. It also addresses a comparison between consortium-based education and the National AACN Essentials of Critical Care Orientation (ECCO) Program.