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1.
Gan To Kagaku Ryoho ; 47(5): 801-806, 2020 May.
Artigo em Japonês | MEDLINE | ID: mdl-32408323

RESUMO

Screening for total pain and sharing of patient information including adverse events for patients receiving chemotherapy by medical staff is needed in clinical practice. We introduced a sharing system for patient-oriented outcome sheets via a touch panel at an outpatient chemotherapy clinic. This study aimed to assess whether the system contributes to the improved management of treatment-related adverse events. We retrospectively analyzed data from a total of 215 patients at Ehime University Hospital using their electronic medical records from April to August 2015. Forty of these patients had received interventions relating to treatment-related adverse events. The proportion of a total number of interventions before and after the sharing system was 42/282(14.9%)and 45/215(20.9%), respectively. The proportion of a total number of interventions at the first course of outpatient chemotherapy also increased from 9/40(22.5%)to 14/40(35%)compared with before the sharing system. The purpose of interventions were for insomnia, anorexia, and cancer-related pain, etc., listed in order of degree of frequency. These results suggest that a sharing system of patient-reported interview sheets contributes to tracking treatment -related adverse events and aids in ensuring interventions can be efficiently performed by multidisciplinary team members.


Assuntos
Antineoplásicos/efeitos adversos , Instituições de Assistência Ambulatorial , Humanos , Pacientes Ambulatoriais , Medidas de Resultados Relatados pelo Paciente , Estudos Retrospectivos
2.
Int J Clin Oncol ; 23(2): 375-381, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-29063983

RESUMO

BACKGROUND: Follicular lymphoma (FL) is the most common type of non-Hodgkin lymphoma (NHL), with indolent progression. Several treatment options are selected, based not only on disease status, quality of life (QOL), and age of patient, but also on recent increasing medical costs. We retrospectively analysed the first-line treatment of FL with regard to treatment outcomes and medical economics, and discuss the appropriate strategies for FL. METHODS: Data on a total of 69 newly-diagnosed patients with FL was retrospectively collected from 2001 to 2015. RESULTS: The median age of the patients was 60 years and the median follow-up was 58 months. A total of 25 cases with FL were treated with R monotherapy, and 28 cases were treated with R-CHOP as first-line treatment. The factors affecting the decision of physicians to use R or R-CHOP treatment were serum level of lactate dehydrogenase (LDH) and disease stage. The first-line treatment-associated survival did not show any statistical differences between R and R-CHOP. The average hospitalization and average of all medical costs during the first-line treatment were 4.1 days (R) versus 55.7 days (R-CHOP), and JPY 1,707,693 (USD 15,324) (R) versus JPY 2,136,117 (USD 19,170) (R-CHOP), respectively. CONCLUSION: R monotherapy for patients whose diseases show low tumor burden and who are not candidates for local treatment has benefits as a first-line treatment compared to R-CHOP, based on the patients' QOL and medical economics.


Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/economia , Linfoma Folicular/tratamento farmacológico , Linfoma Folicular/mortalidade , Adulto , Idoso , Idoso de 80 Anos ou mais , Anticorpos Monoclonais Murinos/economia , Anticorpos Monoclonais Murinos/uso terapêutico , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Custos e Análise de Custo , Ciclofosfamida/economia , Ciclofosfamida/uso terapêutico , Doxorrubicina/economia , Doxorrubicina/uso terapêutico , Custos de Medicamentos , Feminino , Humanos , Imunoterapia/economia , Imunoterapia/métodos , Linfoma Folicular/economia , Masculino , Pessoa de Meia-Idade , Prednisona/economia , Prednisona/uso terapêutico , Qualidade de Vida , Estudos Retrospectivos , Rituximab/administração & dosagem , Rituximab/economia , Resultado do Tratamento , Vincristina/economia , Vincristina/uso terapêutico
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