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Food Chem Toxicol ; 158: 112615, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34656696

RESUMO

Dark tea, a unique tea fermented primarily in China, has numerous potential beneficial effects. However, harmful substances present in dark tea have provoked significant concern. To conduct a quantitative benefit-risk assessment of dark tea for Chinese residents and provide guidance on rational consumption, a framework of Benefit-Risk Analysis for Foods (BRAFO) and meta-analysis was applied to construct a disability-adjusted life year (DALY). Based on the BRAFO-tiered approach, a reference scenario (no intake) and an alternative scenario (intake of 3 cups/day) were determined. The overall health impacts of dark tea were simulated by comparing the risks of fluoride and AF with benefits of reduced-risk to coronary heart disease (CHD) and diabetes in different scenarios. Three cups of fermented tea consumed per day decreased risks of CHD and diabetes by 8.16% and 12.77% respectively. After quantitative integration of information, the ultimate net health effect was found to be -1958.827 illustrating that the benefits of drinking three cups of dark tea per day outweigh the risks. However, considering the uncertainties in the process, decision-makers should proceed with caution, consulting additional well-conducted studies and further managing harmful substances in dark tea.


Assuntos
Aflatoxinas , Camellia sinensis , Doença das Coronárias/prevenção & controle , Diabetes Mellitus/prevenção & controle , Anos de Vida Ajustados por Deficiência , Fluoretos , Preparações de Plantas/química , Animais , China , Exposição Ambiental/efeitos adversos , Feminino , Fermentação , Contaminação de Alimentos , Humanos , Masculino , Preparações de Plantas/efeitos adversos , Preparações de Plantas/uso terapêutico , Medição de Risco , Chá/efeitos adversos , Chá/química
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