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1.
PLoS One ; 14(3): e0213647, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30908492

RESUMO

OBJECTIVES: To measure value in the delivery of inpatient care and to quantify its variation across U.S. regions. DATA SOURCES / STUDY SETTING: A random (20%) sample of 33,713 elderly fee-for-service Medicare beneficiaries treated in 2,232 hospitals for a heart attack in 2013. STUDY DESIGN: We estimate a production function for inpatient care, defining output as stays with favorable patient outcomes in terms of survival and readmission. The regression model includes hospital inputs measured by treatment costs, as well as patient characteristics. Region-level effects in the production function are used to estimate the productivity and value of the care delivered by hospitals within regions. DATA COLLECTION / EXTRACTION METHODS: Medicare claims and enrollment files, linked to the Dartmouth Atlas of Health Care and Inpatient Prospective Payment System Impact Files. PRINCIPAL FINDINGS: Hospitals in the hospital referral region at the 90th percentile of the value distribution delivered 54% more high-quality stays than hospitals at the 10th percentile could have delivered, after adjusting for treatment costs and patient severity. CONCLUSIONS: Variation in the delivery of high-value inpatient care points to opportunities for better quality and lower costs.


Assuntos
Custos de Cuidados de Saúde , Pesquisa sobre Serviços de Saúde , Hospitalização/economia , Pacientes Internados , Readmissão do Paciente , Idoso , Idoso de 80 Anos ou mais , Bases de Dados Factuais , Economia Hospitalar , Planos de Pagamento por Serviço Prestado/economia , Feminino , Geografia , Hospitais/estatística & dados numéricos , Humanos , Masculino , Medicare/estatística & dados numéricos , Mortalidade , Sistema de Pagamento Prospectivo/economia , Qualidade da Assistência à Saúde , Risco , Resultado do Tratamento , Estados Unidos
2.
Health Serv Res ; 51(4): 1561-83, 2016 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-26800094

RESUMO

OBJECTIVE: Assess the relative importance of proximity and other hospital characteristics in the choice of hospital for breast cancer surgery by race/ethnicity. DATA: SEER-Medicare data. STUDY DESIGN: Observational study of women aged >65 years receiving surgery for stage I/II/III breast cancer diagnosed in 1992-2007 in Detroit (N = 10,746 white/black), Atlanta (N = 4,018 white/black), Los Angeles (N = 9,433 white/black/Asian/Hispanic), and San Francisco (N = 4,856 white/black/Asian). We calculated the distance from each patient's census tract of residence to each area hospital. We estimated discrete choice models for the probability of receiving surgery at each hospital based on distance and assessed whether deviations from these predictions entailed interactions of hospital characteristics with the patient's race/ethnicity. We identified high-quality hospitals by rates of adjuvant radiation therapy and by survey measures of patient experiences, and we assessed how observed surgery rates at high-quality hospitals deviated from those predicted based on distance alone. PRINCIPAL FINDINGS: Proximity was significantly associated with hospital choice in all areas. Minority more often than white breast cancer patients had surgery at hospitals with more minority patients, those treating more Medicaid patients, and in some areas, lower quality hospitals. CONCLUSIONS: Residential location alone does not explain concentration of racial/ethnic-minority breast cancer surgery patients in certain hospitals that are sometimes of lower quality.


Assuntos
Neoplasias da Mama/etnologia , Comportamento de Escolha , Geografia Médica , Disparidades em Assistência à Saúde/estatística & dados numéricos , Hospitais/estatística & dados numéricos , Negro ou Afro-Americano/estatística & dados numéricos , Idoso , Asiático/estatística & dados numéricos , Neoplasias da Mama/cirurgia , Feminino , Hispânico ou Latino/estatística & dados numéricos , Humanos , Mastectomia , Medicaid , Medicare , Grupos Minoritários , Programa de SEER , Estados Unidos , População Branca/estatística & dados numéricos
3.
J Natl Cancer Inst ; 107(1): 336, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25432408

RESUMO

BACKGROUND: In the United States, patients who enroll in chemotherapy trials seldom reflect the attributes of the general population with cancer, as they are often younger, more functional, and have less comorbidity. We compared survival following three chemotherapy regimens according to the setting in which care was delivered (ie, clinical trial vs usual care) to determine the generalizability of clinical trial results to unselected elderly Medicare patients. METHODS: Using SEER-Medicare data, we estimated survival for elderly patients (ie, age 65 years or older, n = 14097) with advanced pancreatic or lung cancer following receipt of one of three guideline-recommended first-line chemotherapy regimens. We compared their survival to that of similarly treated clinical trial enrollees, without age restrictions, with the same diagnosis and stage (n = 937). All statistical tests were two-sided. RESULTS: Trial patients were 9.5 years younger than elderly Medicare patients. Medicare patients were more often white and tended to live in areas of greater educational attainment than trial enrollees. For each tumor type, Medicare patients who were 75 years or older had median survivals that were six to eight weeks shorter than those of trial patients (4.3 vs 5.8 months following treatment with single agent gemcitabine for advanced pancreatic cancer, P = .03; 7.3 vs 8.9 months following treatment with carboplatin and paclitaxel for stage IV non-small cell lung cancer, P = .91; 8.2 vs 10.2 months following treatment with CDDP/ VP16 for extensive stage small cell lung cancer, P ≤ .01), whereas younger Medicare patients had survival times that were similar to those of trial patients. CONCLUSIONS: Results of clinical trials for advanced pancreatic cancer and lung cancers tended to correctly estimate survival for Medicare patients aged 65 to 74 years, but to overestimate survival for older Medicare patients by six to eight weeks. These estimates of Medicare patients' survival may aid subsequent patients and their oncologists in treatment decision-making.


Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Ensaios Clínicos como Assunto , Neoplasias Pulmonares/tratamento farmacológico , Neoplasias Pulmonares/mortalidade , Neoplasias Pancreáticas/tratamento farmacológico , Neoplasias Pancreáticas/mortalidade , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Escolaridade , Feminino , Humanos , Estimativa de Kaplan-Meier , Neoplasias Pulmonares/patologia , Masculino , Medicare , Pessoa de Meia-Idade , Neoplasias Pancreáticas/patologia , Prognóstico , Programa de SEER , Estados Unidos
4.
Med Care ; 52(9): 809-17, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-25119954

RESUMO

BACKGROUND: The social and medical environments that surround people are each independently associated with their cancer course. The extent to which these characteristics may together mediate patients' cancer care and outcomes is not known. METHODS: Using multilevel methods and data, we studied elderly breast and colorectal cancer patients (level I) within urban social (level II: ZIP code tabulation area) and health care (level III: hospital service area) contexts. We sought to determine (1) which, if any, observable social and medical contextual attributes were associated with patient cancer outcomes after controlling for observable patient attributes, and (2) the magnitude of residual variation in patient cancer outcomes at each level. RESULTS: Numerous patient attributes and social area attributes, including poverty, were associated with unfavorable patient cancer outcomes across the full clinical cancer continuum for both cancers. Health care area attributes were not associated with patient cancer outcomes. After controlling for observable covariates at all 3 levels, there was substantial residual variation in patient cancer outcomes at all levels. CONCLUSIONS: After controlling for patient attributes known to confer risk of poor cancer outcomes, we find that neighborhood socioeconomic disadvantage exerts an independent and deleterious effect on residents' cancer outcomes, but the area supply of the specific types of health care studied do not. Multilevel interventions targeted at cancer patients and their social areas may be useful. We also show substantial residual variation in patient outcomes across social and health care areas, a finding potentially relevant to traditional small area variation research methods.


Assuntos
Neoplasias da Mama/epidemiologia , Neoplasias da Mama/terapia , Neoplasias Colorretais/epidemiologia , Neoplasias Colorretais/terapia , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Feminino , Acessibilidade aos Serviços de Saúde/estatística & dados numéricos , Humanos , Masculino , Medicare/estatística & dados numéricos , Características de Residência/estatística & dados numéricos , Programa de SEER , Análise de Pequenas Áreas , Fatores Socioeconômicos , Resultado do Tratamento , Estados Unidos , População Urbana
5.
J Geriatr Oncol ; 5(3): 230-7, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-24594119

RESUMO

OBJECTIVE: Medicare claims can be useful in chemotherapy-related comparative effectiveness research (CER) estimating survival, but methods for estimating patients' treatment morbidity are currently lacking. We sought to determine if patients' health care use in the claims is a marker of treatment morbidity. MATERIALS AND METHODS: For 249 elderly Medicare patients with breast or colon cancer who were treated in two adjuvant clinical trials, we merged patients' National Cancer Institute Common Toxicity Criteria for Adverse Events (CTC AEs) trial data with their contemporaneous Medicare claims. We estimated associations of patients' grade ≥3 CTC AE counts and their use of two types of hospital-based health care in claims (i.e., emergency room (ER) visits and hospitalizations). RESULTS: ER visits and hospitalizations were significantly positively associated with grade ≥3 CTC AE counts incurred by patients during the study. Eight percent of patients without any grade ≥3 CTC AEs had one or more hospitalizations during the observation period compared to 43% of patients with three or more grade ≥3 CTC AEs (p<0.01). Those who were hospitalized at least once had more than three times the rate of grade ≥3 CTC AEs (IRR 3.70, 95% CI: 2.53-5.40) compared to those who were not. With each hospitalization, the daily incidence rate of any grade ≥3 CTC AE more than doubled (IRR 2.10, 95% CI: 1.54-2.86). CONCLUSIONS: Because hospitalization is strongly associated with clinically significant toxicity it may be a useful outcome for Medicare claim-based CER comparing treatment morbidity for elderly patients receiving different adjuvant chemotherapy regimens.


Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/efeitos adversos , Neoplasias da Mama/tratamento farmacológico , Neoplasias do Colo/tratamento farmacológico , Hospitalização/estatística & dados numéricos , Idoso , Quimioterapia Adjuvante , Ensaios Clínicos como Assunto , Estudos de Coortes , Pesquisa Comparativa da Efetividade , Feminino , Humanos , Revisão da Utilização de Seguros , Masculino , Medicare/estatística & dados numéricos , Aceitação pelo Paciente de Cuidados de Saúde/estatística & dados numéricos , Qualidade de Vida , Estados Unidos
6.
Health Aff (Millwood) ; 32(5): 873-81, 2013 May.
Artigo em Inglês | MEDLINE | ID: mdl-23650320

RESUMO

Lowering both Medicare spending and the rate of Medicare spending growth is important for the nation's fiscal health. Policy makers in search of ways to achieve these reductions have looked at the role that supplemental coverage for Medicare beneficiaries plays in Medicare spending. Supplemental coverage makes health care more affordable for beneficiaries but also makes beneficiaries insensitive to the cost of their care, thereby increasing the demand for care. Ours is the first empirical study to investigate whether supplemental Medicare coverage is associated with higher rates of spending growth over time. We found that supplemental insurance coverage was associated with significantly higher rates of overall spending growth. Specifically, employer-sponsored and self-purchased supplemental coverage were associated with annual total spending growth rates of 7.17 percent and 7.18 percent, respectively, compared to 6.08 percent annual growth for beneficiaries without supplemental coverage. Results for Medicare program spending were more equivocal, however. Our results are consistent with the belief that current trends away from generous employer-sponsored supplemental coverage and efforts to restrict the generosity of supplemental coverage may slow spending growth.


Assuntos
Gastos em Saúde/estatística & dados numéricos , Seguro de Saúde (Situações Limítrofes)/economia , Medicare/economia , Idoso , Idoso de 80 Anos ou mais , Dedutíveis e Cosseguros/economia , Dedutíveis e Cosseguros/estatística & dados numéricos , Feminino , Humanos , Cobertura do Seguro/economia , Seguro de Saúde (Situações Limítrofes)/estatística & dados numéricos , Masculino , Modelos Econômicos , Estados Unidos
7.
JAMA Intern Med ; 173(1): 15-21, 2013 Jan 14.
Artigo em Inglês | MEDLINE | ID: mdl-23336095

RESUMO

BACKGROUND: Prior to 2010, Medicare payments for consultations (commonly billed by specialists) were substantially higher than for office visits of similar complexity (commonly billed by primary care physicians). In January 2010, Medicare eliminated consultation payments from the Part B Physician Fee Schedule and increased fees for office visits. This change was intended to be budget neutral and to decrease payments to specialists while increasing payments to primary care physicians. We assessed the impact of this policy on spending, volume, and complexity for outpatient office encounters in 2010. METHODS: We examined outpatient claims from 2007 through 2010 for 2 247 810 Medicare beneficiaries with Medicare Supplemental (Medigap) coverage through large employers in the Thomson Reuters MarketScan Database. We used segmented regression analysis to study changes in spending, volume, and complexity of office encounters adjusted for age, sex, health status, secular trends, seasonality, and hospital referral region. RESULTS: "New" office visits largely replaced consultations in 2010. An average of $10.20 more was spent per beneficiary per quarter on physician encounters after the policy (6.5% increase). The total volume of physician encounters did not change significantly. The increase in spending was largely explained by higher office-visit fees from the policy and a shift toward higher-complexity visits to both specialists and primary care physicians. CONCLUSIONS: The elimination of consultations led to a net increase in spending on visits to both primary care physicians and specialists. Higher prices, partially owing to the subjectivity of codes in the physician fee schedule, explained the spending increase, rather than higher volumes.


Assuntos
Economia , Medicare , Médicos de Atenção Primária/economia , Encaminhamento e Consulta , Especialização/economia , Idoso , Idoso de 80 Anos ou mais , Demografia , Economia/estatística & dados numéricos , Economia/tendências , Tabela de Remuneração de Serviços/economia , Tabela de Remuneração de Serviços/legislação & jurisprudência , Feminino , Gastos em Saúde/estatística & dados numéricos , Humanos , Masculino , Medicare/estatística & dados numéricos , Medicare/tendências , Visita a Consultório Médico/economia , Encaminhamento e Consulta/economia , Encaminhamento e Consulta/legislação & jurisprudência , Encaminhamento e Consulta/tendências , Fatores Socioeconômicos , Estados Unidos
8.
Cancer ; 119(2): 250-8, 2013 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-22833148

RESUMO

BACKGROUND: Massachusetts law requires all residents to maintain a minimum level of health insurance, and rates of uninsurance in that state decreased from 6.4% in 2006 to 1.9% in 2010. The authors of this report assessed whether health insurance expansion was associated with use of mammography and earlier stage at breast cancer diagnosis. METHODS: By using a prereform/postreform design with a concurrent control (California), mammography rates in the last year were assessed using the Behavioral Risk Factor Surveillance System survey and the diagnosis of stage I (vs II/III/IV) breast cancers based on cancer registry data among women ages 41 to 64. Propensity score analyses were used to compare California women who were most similar to women in Massachusetts with Massachusetts women. RESULTS: Among propensity-weighted cohorts, adjusted mammography rates in Massachusetts were 69.2% in 2006, 69.5% in 2008, and 69.0% in 2010. In California, the rates were 59% in 2006, 60.3% in 2008, and 56.2% in 2010 (P = .89 for interaction by state for 2010 vs 2006). Among propensity-weighted cohorts, adjusted rates of diagnosis with stage I cancers were 52.2% in 2006, 53.5% in 2007, and 52.4% in 2008 in Massachusetts versus 46.4% in 2006, 46.3% in 2007, and 45.7% in 2008 in California (P = .58 for interaction by state for 2010 vs 2006). CONCLUSIONS: Health insurance reform in Massachusetts was not associated with increased rates of mammography or earlier stage at diagnosis compared with California, possibly because of insurance and mammography rates that already were high. Additional research is needed to assess the impact of insurance expansions in other populations, especially those with higher uninsurance rates.


Assuntos
Neoplasias da Mama/patologia , Reforma dos Serviços de Saúde/legislação & jurisprudência , Seguro Saúde/legislação & jurisprudência , Mamografia/estatística & dados numéricos , Adulto , Neoplasias da Mama/diagnóstico por imagem , California , Feminino , Humanos , Massachusetts , Pessoa de Meia-Idade , Estadiamento de Neoplasias
10.
Med Care ; 50(11): 934-9, 2012 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-23047782

RESUMO

BACKGROUND: Cost-sharing requirements employed by health insurers to discourage the unnecessary use of medications may lead to underutilization of recommended treatment regimens and suboptimal quality of care. Value-based insurance design (VBID) programs seek to address these problems by lowering copayments to promote adherence to "high-value" medications that have been proven to be clinically beneficial. VBID evaluations to date have focused on programs implemented by self-insured employers. This study is among the first to assess the VBID program of a health plan. METHODS: We examined a VBID program for statins implemented by a large regional health plan in 2008 and assessed its effect on medication adherence. Copayments on VBID brand statins were reduced by 42.9% for employer-sponsored plans (the treatment group) and increased by 16.7% for state-sponsored plans (the control group) between the preintervention and postintervention periods. Propensity score weights were used to balance the treatment and control groups on observed characteristics. We evaluated the impact of the VBID program on adherence using an econometric model with a difference-in-difference design. RESULTS: Medication adherence increased 2.7 percentage points (P=0.033) among VBID brand statin users in the treatment group relative to the control group. With a baseline adherence rate of 77.6%, nonadherence was reduced by 11.9%. CONCLUSIONS: Copayment reductions on selected statin medications contributed to improvements in adherence. As one of the first studies to evaluate a health plan's VBID program, our findings demonstrate that insurer-based VBID programs may yield results similar to those achieved by employer-based programs.


Assuntos
Custo Compartilhado de Seguro/economia , Custo Compartilhado de Seguro/métodos , Inibidores de Hidroximetilglutaril-CoA Redutases/administração & dosagem , Inibidores de Hidroximetilglutaril-CoA Redutases/economia , Seguradoras/economia , Feminino , Humanos , Masculino , Adesão à Medicação/estatística & dados numéricos , Pessoa de Meia-Idade , Pontuação de Propensão , Estados Unidos
11.
Breast Cancer Res Treat ; 135(3): 893-906, 2012 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-22949130

RESUMO

Although younger women with breast cancer have the most to gain from receipt of optimal care, few data are available regarding their receipt of locoregional breast cancer treatments. We identified 317,596 women aged 18-64 who were diagnosed with invasive breast cancer at hospitals reporting to the National Cancer Database, a large national cancer registry, during 2004-2008. We used multivariable logistic regression to assess the association of patient age with mastectomy versus breast-conserving surgery (BCS), radiation with BCS, and postmastectomy radiation therapy (PMRT) with varying indications, adjusting for patient, clinical, and facility characteristics. Overall, 4 % of women were 35 years old or younger and 7 % were 36-40 years old. Women ≤age 40 were significantly more likely to have mastectomy than BCS compared with older women (57 % for age ≤35 and 52 % for ages 36-40 vs. 35 % for ages 61-64, adjusted odds ratio [OR] for age ≤35 = 2.03; 95 % confidence interval (CI) 1.93-2.14 and OR for ages 36-40 = 1.76; 95 % CI 1.69-1.84). Younger women were less likely to receive radiation if BCS was performed (69 and 73 vs. 80 %, OR for age ≤35 = 0.69; 95 % CI 0.65-0.74 and OR for ages 36-40 = 0.74; 95 % CI 0.70-0.78). For those who underwent mastectomy, overall rates of PMRT were low, although women ≤age 35 and ages 36-40 (vs. ages 61-64) were more likely to receive PMRT regardless of clinical indications. Our study suggests that young women with breast cancer may not be receiving optimal locoregional therapy. Efforts are needed to confirm these findings, further understand barriers to care, and increase the receipt of appropriate adjuvant radiation therapy among young women to improve their disease-free and overall survival.


Assuntos
Neoplasias da Mama/cirurgia , Neoplasias da Mama/terapia , Mastectomia/estatística & dados numéricos , Adolescente , Adulto , Neoplasias da Mama/radioterapia , Estudos de Coortes , Intervalos de Confiança , Feminino , Humanos , Modelos Logísticos , Mastectomia Segmentar/estatística & dados numéricos , Medicaid , Medicare , Pessoa de Meia-Idade , Razão de Chances , Estados Unidos , Adulto Jovem
12.
J Clin Oncol ; 30(26): 3250-7, 2012 Sep 10.
Artigo em Inglês | MEDLINE | ID: mdl-22869877

RESUMO

PURPOSE: Area social deprivation is associated with unfavorable health outcomes of residents across the full clinical course of cancer from the stage at diagnosis through survival. We sought to determine whether area social factors are associated with the area health care supply. PATIENTS AND METHODS: We studied the area supply of health services required for the provision of guideline-recommended care for patients with breast cancer and colorectal cancer (CRC) in each of the following three distinct clinical domains: screening, treatment, and post-treatment surveillance. We characterized area social factors in 3,096 urban zip code tabulation areas by using Census Bureau data and the health care supply in the corresponding 465 hospital service areas by using American Hospital Association, American Medical Association, and US Food and Drug Administration data. In two-level hierarchical models, we assessed associations between social factors and the supply of health services across areas. RESULTS: We found no clear associations between area social factors and the supply of health services essential to the provision of guideline recommended breast cancer and CRC care in urban areas. The measures of health service included the supply of physicians who facilitate screening, treatment, and post-treatment care and the supply of facilities required for the same services. CONCLUSION: Because we found that the supply of types of health care required for the provision of guideline-recommended cancer care for patients with breast cancer and CRC did not vary with markers of area socioeconomic disadvantage, it is possible that previously reported unfavorable breast cancer and CRC outcomes among individuals living in impoverished areas may have occurred despite an apparent adequate area health care supply.


Assuntos
Neoplasias da Mama/diagnóstico , Neoplasias da Mama/terapia , Neoplasias Colorretais/diagnóstico , Neoplasias Colorretais/terapia , Acessibilidade aos Serviços de Saúde , Fatores Socioeconômicos , Assistência ao Convalescente , Feminino , Instalações de Saúde , Humanos , Masculino , Médicos/provisão & distribuição
13.
Health Aff (Millwood) ; 31(8): 1885-94, 2012 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-22786651

RESUMO

Seven provider organizations in Massachusetts entered the Blue Cross Blue Shield Alternative Quality Contract in 2009, followed by four more organizations in 2010. This contract, based on a global budget and pay-for-performance for achieving certain quality benchmarks, places providers at risk for excessive spending and rewards them for quality, similar to the new Pioneer Accountable Care Organizations in Medicare. We analyzed changes in spending and quality associated with the Alternative Quality Contract and found that the rate of increase in spending slowed compared to control groups, more so in the second year than in the first. Overall, participation in the contract over two years led to savings of 2.8 percent (1.9 percent in year 1 and 3.3 percent in year 2) compared to spending in nonparticipating groups. Savings were accounted for by lower prices achieved through shifting procedures, imaging, and tests to facilities with lower fees, as well as reduced utilization among some groups. Quality of care also improved compared to control organizations, with chronic care management, adult preventive care, and pediatric care within the contracting groups improving more in year 2 than in year 1. These results suggest that global budgets with pay-for-performance can begin to slow underlying growth in medical spending while improving quality of care.


Assuntos
Orçamentos , Contratos , Gastos em Saúde , Melhoria de Qualidade/organização & administração , Qualidade da Assistência à Saúde , Adolescente , Adulto , Planos de Seguro Blue Cross Blue Shield , Estudos de Coortes , Controle de Custos/métodos , Feminino , Gastos em Saúde/tendências , Humanos , Masculino , Massachusetts , Pessoa de Meia-Idade , Estudos de Casos Organizacionais , Reembolso de Incentivo , Adulto Jovem
14.
Stat Med ; 30(29): 3447-60, 2011 Dec 20.
Artigo em Inglês | MEDLINE | ID: mdl-21976366

RESUMO

The multivariate normal (MVN) distribution is arguably the most popular parametric model used in imputation and is available in most software packages (e.g., SAS PROC MI, R package norm). When it is applied to categorical variables as an approximation, practitioners often either apply simple rounding techniques for ordinal variables or create a distinct 'missing' category and/or disregard the nominal variable from the imputation phase. All of these practices can potentially lead to biased and/or uninterpretable inferences. In this work, we develop a new rounding methodology calibrated to preserve observed distributions to multiply impute missing categorical covariates. The major attractiveness of this method is its flexibility to use any 'working' imputation software, particularly those based on MVN, allowing practitioners to obtain usable imputations with small biases. A simulation study demonstrates the clear advantage of the proposed method in rounding ordinal variables and, in some scenarios, its plausibility in imputing nominal variables. We illustrate our methods on a widely used National Survey of Children with Special Health Care Needs where incomplete values on race posed a valid threat on inferences pertaining to disparities.


Assuntos
Inquéritos Epidemiológicos/estatística & dados numéricos , Análise Multivariada , Avaliação das Necessidades/estatística & dados numéricos , Distribuição Normal , Adolescente , Viés , Criança , Pré-Escolar , Simulação por Computador , Feminino , Pesquisas sobre Atenção à Saúde/estatística & dados numéricos , Disparidades nos Níveis de Saúde , Disparidades em Assistência à Saúde/estatística & dados numéricos , Humanos , Lactente , Masculino , Grupos Raciais/estatística & dados numéricos , Software/estatística & dados numéricos
15.
N Engl J Med ; 365(10): 909-18, 2011 Sep 08.
Artigo em Inglês | MEDLINE | ID: mdl-21751900

RESUMO

BACKGROUND: In 2009, Blue Cross Blue Shield of Massachusetts (BCBS) implemented a global payment system called the Alternative Quality Contract (AQC). Provider groups in the AQC system assume accountability for spending, similar to accountable care organizations that bear financial risk. Moreover, groups are eligible to receive bonuses for quality. METHODS: Seven provider organizations began 5-year contracts as part of the AQC system in 2009. We analyzed 2006-2009 claims for 380,142 enrollees whose primary care physicians (PCPs) were in the AQC system (intervention group) and for 1,351,446 enrollees whose PCPs were not in the system (control group). We used a propensity-weighted difference-in-differences approach, adjusting for age, sex, health status, and secular trends to isolate the treatment effect of the AQC in comparisons of spending and quality between the intervention group and the control group. RESULTS: Average spending increased for enrollees in both the intervention and control groups in 2009, but the increase was smaller for enrollees in the intervention group--$15.51 (1.9%) less per quarter (P=0.007). Savings derived largely from shifts in outpatient care toward facilities with lower fees; from lower expenditures for procedures, imaging, and testing; and from a reduction in spending for enrollees with the highest expected spending. The AQC system was associated with an improvement in performance on measures of the quality of the management of chronic conditions in adults (P<0.001) and of pediatric care (P=0.001), but not of adult preventive care. All AQC groups met 2009 budget targets and earned surpluses. Total BCBS payments to AQC groups, including bonuses for quality, are likely to have exceeded the estimated savings in year 1. CONCLUSIONS: The AQC system was associated with a modest slowing of spending growth and improved quality of care in 2009. Savings were achieved through changes in referral patterns rather than through changes in utilization. The long-term effect of the AQC system on spending growth depends on future budget targets and providers' ability to further improve efficiencies in practice. (Funded by the Commonwealth Fund and others.).


Assuntos
Serviços Contratados/economia , Gastos em Saúde/estatística & dados numéricos , Sistemas Pré-Pagos de Saúde/economia , Sistemas Pré-Pagos de Saúde/normas , Qualidade da Assistência à Saúde , Adulto , Assistência Ambulatorial/economia , Assistência Ambulatorial/normas , Serviços Contratados/normas , Redução de Custos , Feminino , Gastos em Saúde/tendências , Humanos , Masculino , Massachusetts , Reembolso de Incentivo
16.
Stat Med ; 30(16): 1989-2004, 2011 Jul 20.
Artigo em Inglês | MEDLINE | ID: mdl-21520454

RESUMO

Stochastic curtailment is a sequential method to terminate a study when continuing to the end would be unlikely to change the outcome. This method has been researched most commonly in the context of clinical trials. The current paper explores its use in a different setting: the administration of a health questionnaire to patients via computer. A classification procedure augmenting logistic regression with stochastic curtailment is introduced to avoid burdening the patients with unnecessary questions. In a real-data simulation using responses from the Medicare Health Outcomes Survey, the new procedure substantially reduced the average number of questions administered with a minimal loss of classification accuracy.


Assuntos
Bioestatística/métodos , Processos Estocásticos , Inquéritos e Questionários , Idoso , Ensaios Clínicos como Assunto/estatística & dados numéricos , Interpretação Estatística de Dados , Feminino , Inquéritos Epidemiológicos/estatística & dados numéricos , Humanos , Masculino , Medicare , Estados Unidos
17.
Health Serv Res ; 46(4): 1022-38, 2011 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-21306369

RESUMO

OBJECTIVE: To determine whether the change in prescription drug insurance coverage associated with Medicare Part D reduced hospitalization rates for conditions sensitive to drug adherence. DATA SOURCES/STUDY SETTING: Hospital discharge data from 2005 to 2007 for 23 states, linked with state-level data on drug coverage. STUDY DESIGN: We use a difference-in-difference-in-differences approach, comparing changes in the probability of hospitalization before and after the introduction of the Part D benefit in 2006, for individuals aged 65 and older (versus individuals aged 60-64) in states with low drug coverage in 2005 (versus those in states with high pre-Part D drug coverage). DATA COLLECTION/EXTRACTION METHODS: Hospitalization rates for selected ambulatory care sensitive conditions in 23 states were computed using data from the Census and Health Care Utilization Project. Drug coverage rates were computed using data from several sources. PRINCIPAL FINDINGS: For the conditions studied, our point estimates suggest that Part D reduced the overall rate of hospitalization by 20.5 per 10,000 (4.1 percent), representing approximately 42,000 admissions, about half of the reduction in admissions over our study period. Conclusions. The increase in drug coverage associated with Medicare Part D had positive effects on the health of elderly Americans, which reduced use of nondrug health care resources.


Assuntos
Doença Crônica/tratamento farmacológico , Doença Crônica/economia , Hospitalização/estatística & dados numéricos , Medicare Part D/estatística & dados numéricos , Adesão à Medicação/estatística & dados numéricos , Idoso , Pesquisa sobre Serviços de Saúde/estatística & dados numéricos , Humanos , Pessoa de Meia-Idade , Estados Unidos
18.
Stat Med ; 30(10): 1137-56, 2011 May 10.
Artigo em Inglês | MEDLINE | ID: mdl-21341300

RESUMO

In designed longitudinal studies, information from the same set of subjects are collected repeatedly over time. The longitudinal measurements are often subject to missing data which impose an analytic challenge. We propose a functional multiple imputation approach modeling longitudinal response profiles as smooth curves of time under a functional mixed effects model. We develop a Gibbs sampling algorithm to draw model parameters and imputations for missing values, using a blocking technique for an increased computational efficiency. In an illustrative example, we apply a multiple imputation analysis to data from the Panel Study of Income Dynamics and the Child Development Supplement to investigate the gradient effect of family income on children's health status. Our simulation study demonstrates that this approach performs well under varying modeling assumptions on the time trajectory functions and missingness patterns.


Assuntos
Interpretação Estatística de Dados , Estudos Longitudinais , Modelos Estatísticos , Algoritmos , Criança , Desenvolvimento Infantil , Pré-Escolar , Simulação por Computador , Humanos , Lactente , Projetos de Pesquisa , Fatores Socioeconômicos
19.
J Natl Cancer Inst ; 103(5): 384-97, 2011 Mar 02.
Artigo em Inglês | MEDLINE | ID: mdl-21317382

RESUMO

BACKGROUND: Clinical trials are critical for evaluating new cancer therapies, but few adult patients participate in them. Physicians have an important role in facilitating patient participation in clinical trials. We examined the characteristics of specialty physicians who participate in clinical trials by enrolling or referring patients, the types of trials in which they participate, and factors associated with physicians who report greater involvement in clinical trials. METHODS: We analyzed data from the Cancer Care Outcomes Research and Surveillance Consortium. The study included 1533 specialty physicians who cared for colorectal and lung cancer patients (496 medical oncologists, 228 radiation oncologists, and 809 surgeons) and completed a survey conducted during 2005-2006 (response rate = 61.0%). Descriptive statistics were used to characterize physicians' personal and practice characteristics, and regression models were used to examine associations between these characteristics and physician participation in clinical trials. All statistical tests were two-sided. RESULTS: A total of 87.8% of medical oncologists, 66.1% of radiation oncologists, and 35.0% of surgeons reported referring or enrolling one or more patients in clinical trials during the previous 12 months. The mean number of patients referred or enrolled by these physicians was 17.2 (95% confidence interval [CI] = 15.5 to 18.9) for medical oncologists, 9.5 (95% CI = 7.7 to 11.3) for radiation oncologists, and 12.2 (95% CI = 9.8 to 14.6) for surgeons (P < .001). Specialty type, involvement in teaching, and affiliation with a Community Clinical Oncology Program (CCOP) and/or a National Cancer Institute-designated cancer center were associated with physician trial participation and enrolling more patients (all Ps < .05). Two-thirds of physicians with a CCOP or National Cancer Institute-designated cancer center affiliation reported participating in trials. CONCLUSIONS: Features of specialty physicians' practice environments are associated with their trial participation, but many physicians at CCOPs and cancer centers do not participate.


Assuntos
Ensaios Clínicos como Assunto , Oncologia , Neoplasias , Seleção de Pacientes , Papel do Médico , Relações Médico-Paciente , Médicos/estatística & dados numéricos , Especialidades Cirúrgicas , Adulto , Neoplasias Colorretais/terapia , Feminino , Pesquisas sobre Atenção à Saúde , Humanos , Modelos Logísticos , Neoplasias Pulmonares/terapia , Masculino , Oncologia/estatística & dados numéricos , Pessoa de Meia-Idade , Neoplasias/terapia , Médicos/normas , Distribuição de Poisson , Radioterapia (Especialidade)/estatística & dados numéricos , Especialidades Cirúrgicas/estatística & dados numéricos , Estados Unidos , Recursos Humanos
20.
Cancer ; 117(1): 180-9, 2011 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-20939011

RESUMO

BACKGROUND: Few data are available on how race/ethnicity, insurance, and socioeconomic status (SES) interrelate to influence breast cancer treatment. The authors examined care for a national cohort of breast cancer patients to assess whether insurance and SES were associated with racial/ethnic differences in care. METHODS: The authors used multivariate logistic regression to assess the probability of definitive locoregional therapy, hormone receptor testing, and adjuvant systemic therapy among 662,117 white, black, and Hispanic women diagnosed with invasive breast cancer during 1998-2005 at National Cancer Data Base hospitals. In additional models, the authors included insurance and area-level SES to determine whether these variables were associated with observed racial/ethnic disparities. RESULTS: Most women were white (86%), 10% were black, and 4% were Hispanic. Most had private insurance (51%) or Medicare (41%). Among eligible patients, 80.0% (stage I/II) had definitive locoregional therapy, 98.5% (stage I-IV) had hormone receptor testing, and 53.1% and 50.2% (stage I-III) received adjuvant hormonal therapy and chemotherapy, respectively. After adjustment, black (vs white) women had less definitive locoregional therapy (odds ratio [OR], 0.91; 95% confidence interval [CI], 0.88-0.94), hormonal therapy (OR, 0.90; 95% CI, 0.87-0.93), and chemotherapy (OR, 0.87; 95% CI, 0.84-0.91). Hispanic (vs white) women were also less likely to receive hormonal therapy. Hormone receptor testing did not differ by race/ethnicity. Racial disparities persisted despite adjusting for insurance and SES. CONCLUSIONS: The modest association between black (vs white) race and guideline-recommended breast cancer care was insensitive to adjustment for insurance and area-level SES. Further study is required to better understand disparities and to ensure receipt of care.


Assuntos
Neoplasias da Mama/economia , Neoplasias da Mama/etnologia , Etnicidade , Cobertura do Seguro , Seguro Saúde , Fatores Socioeconômicos , Adulto , Idoso , Idoso de 80 Anos ou mais , População Negra , Neoplasias da Mama/terapia , Quimioterapia Adjuvante , Terapia Combinada , Feminino , Disparidades em Assistência à Saúde , Hispânico ou Latino , Hormônios/uso terapêutico , Humanos , Mastectomia , Grupos Raciais , Radioterapia Adjuvante , Classe Social , População Branca
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