Assessment of thoracic spinal cord electrophysiological activity through magnetoneurography.

OBJECTIVE: Noninvasive and detailed visualization of electrophysiological activity in the thoracic spinal cord through magnetoneurography. METHODS: In five healthy volunteers, magnetic fields around current flowing in the thoracic spinal cord after alternating unilateral and synchronized bilateral sciatic nerve stimulation were measured using a magnetoneurograph system with superconductive quantum interference device biomagnetometers. The current distribution was obtained from the magnetic data by spatial filtering and visualized by superimposing it on the X-ray image. Conduction velocity was calculated using the peak latency of the current waveforms. RESULTS: A sufficiently high magnetic signal intensity and signal-to-noise ratio were obtained in all participants after synchronized bilateral sciatic nerve stimulation. Leading and trailing components along the spinal canal and inward components flowing into the depolarization site ascended to the upper thoracic spine. Conduction velocity of the inward current in the whole thoracic spine was 42.4 m/s. CONCLUSIONS: Visualization of electrophysiological activity in the thoracic spinal cord was achieved through magnetoneurography and a new method for synchronized bilateral sciatic nerve stimulation. Magnetoneurography is expected to be a useful modality in functional assessment of thoracic myelopathy. SIGNIFICANCE: This is the first report to use magnetoneurography to noninvasively visualize electrophysiological activity in the thoracic spinal cord in detail.

A repeatability assessment of sows mated 4-6 days after weaning in breeding herds.

The objectives of this study were to investigate the associations of weaning-to-first-mating interval (WMI) groups with reproductive performance, to determine the repeatability and the correlation coefficients in WMI groups between consecutive parities, and to investigate factors associated with the proportion of sows having WMI 4-6 days. This study was conducted using 55,690 parity records of 11,991 sows born during 1999 in 94 herds. Five groups of WMI were formed: 0-3, 4-6, 7-20, 21-27, and > or =28 days. The correlation and the repeatability of the WMI groups were determined using correlation analysis and variance component analysis. Mixed-effects models were used to analyze the associations of WMI groups with reproductive performance, and the associations of parity, lactation length (LL), and nursing piglets with the proportion of sows having WMI 4-6 days. The overall proportion of the WMI 4-6 days was 82.3%. Sows with WMI 4-6 days had the highest farrowing rate, and had more pigs born alive than those with WMI 7-20 days (P<0.01). At each farrowed parity, sows with WMI 4-6 days had higher parity at removal than those with WMI 7-20 days (P<0.01). The repeatability of the WMI groups was low (0.08), and the correlation coefficients of WMI groups between consecutive parities were also low (0.10< or = r< or =0.18; P<0.01). More than 85.9% of sows with WMI 4-6 days were mated on 4-6 days postweaning at subsequent parity. Meanwhile, 65.8-83.9% of sows with WMI 0-3 or > or =7 days were also mated on 4-6 days postweaning at subsequent parity. Additionally, sows with parity > or =2, LL 24-28 days, and 9-10 nursing piglets were more likely to have WMI 4-6 days (P<0.01). In conclusion, sows having any WMI were more likely to be mated on 4-6 days postweaning at subsequent parity, and sows mated on 4-6 days had higher reproductive performance and higher longevity. Increased LL may increase the proportion of sows having WMI 4-6 days.