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2.
Artigo em Inglês | MEDLINE | ID: mdl-31796407

RESUMO

We propose an objective approach to assess the quality of video blending. Blending is a fundamental operation in video editing, which can smooth the intensity changes of relevant regions. However blending also generates artefacts such as bleeding and ghosting. To assess the quality of the blended videos, our approach considers the illuminance consistency as a positive aspect while regard the artefacts as a negative aspect. Temporal coherence between frames is also considered. We evaluate our metric on a video blending dataset where the results of subjective evaluation are available. Experimental results validate the effectiveness of our proposed metric, and shows that this metric gives superior performance over existing video quality metrics.

3.
Cancer ; 124(19): 3849-3855, 2018 10 01.
Artigo em Inglês | MEDLINE | ID: mdl-30321462

RESUMO

BACKGROUND: The diagnosis of chronic myeloid leukemia (CML) is based on characteristic clinical and laboratory findings and the presence of BCR/ABL1 in the blood and/or bone marrow (BM). The utility of BM core biopsy in the workup of patients with CML has been questioned. METHODS: The potential added value of BM biopsy versus aspiration in the workup of a single-institution series of 508 patients with CML at their initial presentation was systematically assessed. BM biopsy was considered essential when it was needed to establish the disease phase, often because blast counts derived from aspirate smears were misleading because the biopsy specimen was more representative of the disease. BM biopsy was considered helpful if it was needed for other nonessential reasons. RESULTS: In 127 patients (25%), BM biopsy was either essential (109 patients) or helpful (18 patients). Patients with accelerated-phase (AP) or blast-phase (BP) disease often required a biopsy related to essential reasons. High-grade myelofibrosis (MF) was more frequent in patients with AP/BP disease than patients with chronic-phase disease (P = .0005), and the identification of BP disease required a BM biopsy assessment in 75% of the patients (P = .001). A follow-up BM evaluation more often yielded inadequate aspirates in patients with inadequate BM aspirates at the time of their initial diagnosis. CONCLUSIONS: BM core biopsy remains valuable in the workup of 25% of patients with CML because it facilitates identification of the disease phase or MF. The initial grade of MF is associated with the disease stage and outcome after therapy. BM biopsy is, therefore, indicated for patients with CML who have AP/BP disease or other findings suggestive of progressive disease.


Assuntos
Medula Óssea/patologia , Leucemia Mielogênica Crônica BCR-ABL Positiva/patologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Biópsia , Crise Blástica/patologia , Exame de Medula Óssea/métodos , Estudos de Coortes , Análise Citogenética/métodos , Feminino , Humanos , Leucemia Mielogênica Crônica BCR-ABL Positiva/diagnóstico , Masculino , Pessoa de Meia-Idade , Técnicas de Diagnóstico Molecular , Valor Preditivo dos Testes , Mielofibrose Primária/patologia , Prognóstico , Estudos Retrospectivos , Adulto Jovem
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