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1.
Vaccine ; 36(30): 4517-4524, 2018 07 16.
Artigo em Inglês | MEDLINE | ID: mdl-29907485

RESUMO

INTRODUCTION: Missed opportunities for vaccination (MOV) can result in inadequate protection against disease. Although healthcare provider reluctance to open multi-dose, lyophilized vaccine vials (particularly the measles-containing vaccine [MCV]) for every eligible child due to concerns about wasting vaccine is a known reason for MOV, little is known about providers' related attitudes and practices. METHODS: In 100 randomly selected health facilities and 24 districts of Cambodia, we surveyed healthcare providers and their district supervisors regarding routine vaccine administration and wastage knowledge and practices, and child caregivers (five per facility) regarding MOV. Vaccine stock management data covering six months were reviewed to calculate facility and district level wastage rates and vaccine usage patterns for six vaccines, including a recently introduced second dose of MCV (MCV2). RESULTS: Response rates were 100/100 (100%) among facility staff, 48/48 (100%) among district staff, and 436/500 (87%) among caregivers. Mean facility-level wastage rates varied from 4% for single-dose diphtheria-tetanus-pertussis-hepatitis B-Haemophilus influenzae type b vaccine to 60% for 10-dose MCV; district-level wastage rates for all vaccines were 0%. Some vaccines had lower wastage rates in large facilities compared to small facilities. The mean MCV wastage rate was the same before and immediately after MCV2 introduction. Providers reported waiting for a mean of two children prior to opening an MCV vial, and 71% of providers reported offering MCV vaccination less frequently during scheduled vaccination sessions than other vaccines. Less than 5% of caregivers reported that their child had been turned away for vaccination, most frequently (65%) for MCV. DISCUSSION: Although the MCV wastage rate in our study was in line with national targets, providers reported waiting for more than one child before opening an MCV vial, contrary to vaccine management guidelines. Future research should explore the causal links between provider practices related to vaccine wastage and their impact on vaccination coverage.


Assuntos
Vacina contra Sarampo/uso terapêutico , Camboja , Humanos , Programas de Imunização/métodos , Esquemas de Imunização
2.
PLoS Negl Trop Dis ; 12(2): e0006268, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-29451879

RESUMO

BACKGROUND: Globally there are an estimated 390 million dengue infections per year, of which 96 million are clinically apparent. In Cambodia, estimates suggest as many as 185,850 cases annually. The World Health Organization global strategy for dengue prevention aims to reduce mortality rates by 50% and morbidity by 25% by 2020. The adoption of integrated vector management approach using community-based methods tailored to the local context is one of the recommended strategies to achieve these objectives. Understanding local knowledge, attitudes and practices is therefore essential to designing suitable strategies to fit each local context. METHODS AND FINDINGS: A Knowledge, Attitudes and Practices survey in 600 randomly chosen households was administered in 30 villages in Kampong Cham which is one of the most populated provinces of Cambodia. KAP surveys were administered to a sub-sample of households where an entomology survey was conducted (1200 households), during which Aedes larval/pupae and adult female Aedes mosquito densities were recorded. Participants had high levels of knowledge regarding the transmission of dengue, Aedes breeding, and biting prevention methods; the majority of participants believed they were at risk and that dengue transmission is preventable. However, self-reported vector control practices did not match observed practices recorded in our surveys. No correlation was found between knowledge and observed practices either. CONCLUSION: An education campaign regarding dengue prevention in this setting with high knowledge levels is unlikely to have any significant effect on practices unless it is incorporated in a more comprehensive strategy for behavioural change, such a COMBI method, which includes behavioural models as well as communication and marketing theory and practice. TRIAL REGISTRATION: ISRCTN85307778.


Assuntos
Aedes , Participação da Comunidade , Dengue/prevenção & controle , Dengue/transmissão , Conhecimentos, Atitudes e Prática em Saúde , Controle de Mosquitos/organização & administração , Mosquitos Vetores , Adolescente , Adulto , Aedes/efeitos dos fármacos , Aedes/fisiologia , Aedes/virologia , Idoso , Idoso de 80 Anos ou mais , Animais , Camboja/epidemiologia , Dengue/epidemiologia , Dengue/virologia , Características da Família , Feminino , Habitação , Humanos , Masculino , Pessoa de Meia-Idade , Controle de Mosquitos/métodos , População Rural , Inquéritos e Questionários , Abastecimento de Água , Adulto Jovem
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