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1.
Epidemiol Psychiatr Sci ; 29: e53, 2019 Aug 27.
Artigo em Inglês | MEDLINE | ID: mdl-31452485

RESUMO

AIMS: To provide cross-national data for selected countries of the Americas on service utilization for psychiatric and substance use disorders, the distribution of these services among treatment sectors, treatment adequacy and factors associated with mental health treatment and adequacy of treatment. METHODS: Data come from data collected from 6710 adults with 12 month mental disorder surveys across seven surveys in six countries in North (USA), Central (Mexico) and South (Argentina, Brazil, Colombia, Peru) America who were interviewed 2001-2015 as part of the World Health Organization (WHO) World Mental Health (WMH) Surveys. DSM-IV diagnoses were made with the WHO Composite International Diagnostic Interview (CIDI). Interviews also assessed service utilization by the treatment sector, adequacy of treatment received and socio-demographic correlates of treatment. RESULTS: Little over one in four of respondents with any 12 month DSM-IV/CIDI disorder received any treatment. Although the vast majority (87.1%) of this treatment was minimally adequate, only 35.3% of cases received treatment that met acceptable quality guidelines. Indicators of social-advantage (high education and income) were associated with higher rates of service use and adequacy, but a number of other correlates varied across survey sites. CONCLUSIONS: These results shed light on an enormous public health problem involving under-treatment of common mental disorders, although the problem is most extreme among people with social disadvantage. Promoting services that are more accessible, especially for those with few resources, is urgently needed.


Assuntos
Transtornos Mentais/terapia , Serviços de Saúde Mental/estatística & dados numéricos , Adolescente , Adulto , Idoso , Transtornos de Ansiedade/epidemiologia , Transtornos de Ansiedade/terapia , Argentina/epidemiologia , Transtorno do Deficit de Atenção com Hiperatividade/epidemiologia , Transtorno do Deficit de Atenção com Hiperatividade/terapia , Transtorno Bipolar/epidemiologia , Transtorno Bipolar/terapia , Brasil/epidemiologia , Colômbia/epidemiologia , Transtornos Disruptivos, de Controle do Impulso e da Conduta/epidemiologia , Transtornos Disruptivos, de Controle do Impulso e da Conduta/terapia , Escolaridade , Utilização de Instalações e Serviços , Feminino , Acessibilidade aos Serviços de Saúde , Humanos , Renda , Masculino , Transtornos Mentais/epidemiologia , México/epidemiologia , Pessoa de Meia-Idade , Transtornos do Humor/epidemiologia , Transtornos do Humor/terapia , Peru/epidemiologia , Guias de Prática Clínica como Assunto , Qualidade da Assistência à Saúde , Índice de Gravidade de Doença , Transtornos Relacionados ao Uso de Substâncias/epidemiologia , Transtornos Relacionados ao Uso de Substâncias/terapia , Estados Unidos/epidemiologia , Adulto Jovem
2.
Psychol Med ; 48(9): 1560-1571, 2018 07.
Artigo em Inglês | MEDLINE | ID: mdl-29173244

RESUMO

BACKGROUND: The treatment gap between the number of people with mental disorders and the number treated represents a major public health challenge. We examine this gap by socio-economic status (SES; indicated by family income and respondent education) and service sector in a cross-national analysis of community epidemiological survey data. METHODS: Data come from 16 753 respondents with 12-month DSM-IV disorders from community surveys in 25 countries in the WHO World Mental Health Survey Initiative. DSM-IV anxiety, mood, or substance disorders and treatment of these disorders were assessed with the WHO Composite International Diagnostic Interview (CIDI). RESULTS: Only 13.7% of 12-month DSM-IV/CIDI cases in lower-middle-income countries, 22.0% in upper-middle-income countries, and 36.8% in high-income countries received treatment. Highest-SES respondents were somewhat more likely to receive treatment, but this was true mostly for specialty mental health treatment, where the association was positive with education (highest treatment among respondents with the highest education and a weak association of education with treatment among other respondents) but non-monotonic with income (somewhat lower treatment rates among middle-income respondents and equivalent among those with high and low incomes). CONCLUSIONS: The modest, but nonetheless stronger, an association of education than income with treatment raises questions about a financial barriers interpretation of the inverse association of SES with treatment, although future within-country analyses that consider contextual factors might document other important specifications. While beyond the scope of this report, such an expanded analysis could have important implications for designing interventions aimed at increasing mental disorder treatment among socio-economically disadvantaged people.


Assuntos
Países Desenvolvidos/estatística & dados numéricos , Países em Desenvolvimento/estatística & dados numéricos , Disparidades em Assistência à Saúde/estatística & dados numéricos , Transtornos Mentais/terapia , Aceitação pelo Paciente de Cuidados de Saúde/estatística & dados numéricos , Fatores Socioeconômicos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Inquéritos Epidemiológicos , Humanos , Internacionalidade , Modelos Logísticos , Masculino , Saúde Mental , Pessoa de Meia-Idade , Análise Multivariada , Psicoterapia , Adulto Jovem
3.
Psychol Med ; 47(10): 1744-1760, 2017 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-28222820

RESUMO

BACKGROUND: Although specific phobia is highly prevalent, associated with impairment, and an important risk factor for the development of other mental disorders, cross-national epidemiological data are scarce, especially from low- and middle-income countries. This paper presents epidemiological data from 22 low-, lower-middle-, upper-middle- and high-income countries. METHOD: Data came from 25 representative population-based surveys conducted in 22 countries (2001-2011) as part of the World Health Organization World Mental Health Surveys initiative (n = 124 902). The presence of specific phobia as defined by the Diagnostic and Statistical Manual of Mental Disorders, fourth edition was evaluated using the World Health Organization Composite International Diagnostic Interview. RESULTS: The cross-national lifetime and 12-month prevalence rates of specific phobia were, respectively, 7.4% and 5.5%, being higher in females (9.8 and 7.7%) than in males (4.9% and 3.3%) and higher in high- and higher-middle-income countries than in low-/lower-middle-income countries. The median age of onset was young (8 years). Of the 12-month patients, 18.7% reported severe role impairment (13.3-21.9% across income groups) and 23.1% reported any treatment (9.6-30.1% across income groups). Lifetime co-morbidity was observed in 60.5% of those with lifetime specific phobia, with the onset of specific phobia preceding the other disorder in most cases (72.6%). Interestingly, rates of impairment, treatment use and co-morbidity increased with the number of fear subtypes. CONCLUSIONS: Specific phobia is common and associated with impairment in a considerable percentage of cases. Importantly, specific phobia often precedes the onset of other mental disorders, making it a possible early-life indicator of psychopathology vulnerability.


Assuntos
Comorbidade , Emprego/estatística & dados numéricos , Saúde Global/estatística & dados numéricos , Saúde Mental/estatística & dados numéricos , Transtornos Fóbicos/epidemiologia , Fatores Socioeconômicos , Adolescente , Adulto , Idade de Início , Feminino , Inquéritos Epidemiológicos/estatística & dados numéricos , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Fatores Sexuais , Organização Mundial da Saúde , Adulto Jovem
4.
Psychol Med ; 46(2): 303-16, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-26436603

RESUMO

BACKGROUND: Although interventions exist to reduce violent crime, optimal implementation requires accurate targeting. We report the results of an attempt to develop an actuarial model using machine learning methods to predict future violent crimes among US Army soldiers. METHOD: A consolidated administrative database for all 975 057 soldiers in the US Army in 2004-2009 was created in the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS). Of these soldiers, 5771 committed a first founded major physical violent crime (murder-manslaughter, kidnapping, aggravated arson, aggravated assault, robbery) over that time period. Temporally prior administrative records measuring socio-demographic, Army career, criminal justice, medical/pharmacy, and contextual variables were used to build an actuarial model for these crimes separately among men and women using machine learning methods (cross-validated stepwise regression, random forests, penalized regressions). The model was then validated in an independent 2011-2013 sample. RESULTS: Key predictors were indicators of disadvantaged social/socioeconomic status, early career stage, prior crime, and mental disorder treatment. Area under the receiver-operating characteristic curve was 0.80-0.82 in 2004-2009 and 0.77 in the 2011-2013 validation sample. Of all administratively recorded crimes, 36.2-33.1% (male-female) were committed by the 5% of soldiers having the highest predicted risk in 2004-2009 and an even higher proportion (50.5%) in the 2011-2013 validation sample. CONCLUSIONS: Although these results suggest that the models could be used to target soldiers at high risk of violent crime perpetration for preventive interventions, final implementation decisions would require further validation and weighing of predicted effectiveness against intervention costs and competing risks.


Assuntos
Piromania/epidemiologia , Homicídio/estatística & dados numéricos , Transtornos Mentais/epidemiologia , Militares/estatística & dados numéricos , Classe Social , Violência/estatística & dados numéricos , Adolescente , Adulto , Fatores Etários , Área Sob a Curva , Crime/estatística & dados numéricos , Feminino , Humanos , Aprendizado de Máquina , Masculino , Transtornos Mentais/terapia , Pessoa de Meia-Idade , Razão de Chances , Curva ROC , Análise de Regressão , Medição de Risco , Estados Unidos/epidemiologia , Adulto Jovem
5.
Psychol Med ; 43(4): 865-79, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-22877824

RESUMO

BACKGROUND: Current trends in population aging affect both recipients and providers of informal family caregiving, as the pool of family caregivers is shrinking while demand is increasing. Epidemiological research has not yet examined the implications of these trends for burdens experienced by aging family caregivers. Method Cross-sectional community surveys in 20 countries asked 13 892 respondents aged 50+ years about the objective (time, financial) and subjective (distress, embarrassment) burdens they experience in providing care to first-degree relatives with 12 broadly defined serious physical and mental conditions. Differential burden was examined by country income category, kinship status and type of condition. RESULTS: Among the 26.9-42.5% respondents in high-, upper-middle-, and low-/lower-middle-income countries reporting serious relative health conditions, 35.7-42.5% reported burden. Of those, 25.2-29.0% spent time and 13.5-19.4% money, while 24.4-30.6% felt distress and 6.4-21.7% embarrassment. Mean caregiving hours per week in those giving any time were 16.6-23.6 (169.9-205.8 h/week per 100 people aged 50+ years). Burden in low-/lower-middle-income countries was 2- to 3-fold higher than in higher-income countries, with any financial burden averaging 14.3% of median family income in high-, 17.7% in upper-middle-, and 39.8% in low-/lower-middle-income countries. Higher burden was reported by women than men and for conditions of spouses and children than parents or siblings. CONCLUSIONS: Uncompensated family caregiving is an important societal asset that offsets rising formal healthcare costs. However, the substantial burdens experienced by aging caregivers across multiple family health conditions and geographic regions threaten the continued integrity of their caregiving capacity. Initiatives supporting older family caregivers are consequently needed, especially in low-/lower-middle-income countries.


Assuntos
Cuidadores/estatística & dados numéricos , Efeitos Psicossociais da Doença , Comparação Transcultural , Saúde da Família/estatística & dados numéricos , Assistência Domiciliar/estatística & dados numéricos , Dinâmica Populacional/tendências , Adulto , Fatores Etários , Cuidadores/economia , Cuidadores/tendências , Criança , Doença Crônica/economia , Doença Crônica/enfermagem , Métodos Epidemiológicos , Família , Saúde da Família/economia , Feminino , Saúde Global , Assistência Domiciliar/economia , Assistência Domiciliar/tendências , Humanos , Masculino , Transtornos Mentais/economia , Transtornos Mentais/enfermagem , Pessoa de Meia-Idade , Fatores Socioeconômicos , Fatores de Tempo , Organização Mundial da Saúde
6.
Mol Psychiatry ; 17(7): 748-58, 2012 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-21577213

RESUMO

Although epilepsy is associated with substantial role impairment, it is also highly comorbid with other physical and mental disorders, making unclear the extent to which impairments associated with epilepsy are actually due to comorbidities. This issue was explored in the National Comorbidity Survey Replication (NCS-R), a nationally representative household survey of 5692 US adults. Medically recognized epilepsy was ascertained with self-report, comorbid physical disorders with a chronic conditions checklist, and comorbid DSM-IV mental disorders with the Composite International Diagnostic Interview. Lifetime epilepsy prevalence was estimated at 1.8%. Epilepsy was comorbid with numerous neurological and general medical conditions and with a sporadic cluster of mental comorbidities (panic, PTSD, conduct disorder and substance use disorders). Although comorbid disorders explain part of the significant gross associations of epilepsy with impairment, epilepsy remains significantly associated with work disability, cognitive impairment and days of role impairment after controlling comorbidities. The net association of epilepsy with days of role impairment after controlling for comorbidities is equivalent to an annualized 89.4 million excess role impairment days among US adults with epilepsy, arguing that role impairment is a major component of the societal costs of epilepsy per se rather than merely due to disorders comorbid with epilepsy. This estimated burden is likely conservative as some parts of the effects of epilepsy are presumably mediated by secondary comorbid disorders.


Assuntos
Doença Crônica/epidemiologia , Efeitos Psicossociais da Doença , Epilepsia/epidemiologia , Transtornos Mentais/epidemiologia , Adulto , Comorbidade , Inquéritos Epidemiológicos/estatística & dados numéricos , Humanos , Prevalência , Estados Unidos/epidemiologia
7.
Psychol Med ; 41(4): 873-86, 2011 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-20553636

RESUMO

BACKGROUND: The methodology commonly used to estimate disease burden, featuring ratings of severity of individual conditions, has been criticized for ignoring co-morbidity. A methodology that addresses this problem is proposed and illustrated here with data from the World Health Organization World Mental Health Surveys. Although the analysis is based on self-reports about one's own conditions in a community survey, the logic applies equally well to analysis of hypothetical vignettes describing co-morbid condition profiles. METHOD: Face-to-face interviews in 13 countries (six developing, nine developed; n=31 067; response rate=69.6%) assessed 10 classes of chronic physical and nine of mental conditions. A visual analog scale (VAS) was used to assess overall perceived health. Multiple regression analysis with interactions for co-morbidity was used to estimate associations of conditions with VAS. Simulation was used to estimate condition-specific effects. RESULTS: The best-fitting model included condition main effects and interactions of types by numbers of conditions. Neurological conditions, insomnia and major depression were rated most severe. Adjustment for co-morbidity reduced condition-specific estimates with substantial between-condition variation (0.24-0.70 ratios of condition-specific estimates with and without adjustment for co-morbidity). The societal-level burden rankings were quite different from the individual-level rankings, with the highest societal-level rankings associated with conditions having high prevalence rather than high individual-level severity. CONCLUSIONS: Plausible estimates of disorder-specific effects on VAS can be obtained using methods that adjust for co-morbidity. These adjustments substantially influence condition-specific ratings.


Assuntos
Doença Crônica/epidemiologia , Efeitos Psicossociais da Doença , Inquéritos Epidemiológicos/estatística & dados numéricos , Transtornos Mentais/epidemiologia , Organização Mundial da Saúde , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Análise de Variância , Comorbidade , Comparação Transcultural , Transtorno Depressivo Maior/epidemiologia , Feminino , Alocação de Recursos para a Atenção à Saúde/estatística & dados numéricos , Política de Saúde , Indicadores Básicos de Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Doenças do Sistema Nervoso/epidemiologia , Medição da Dor , Distúrbios do Início e da Manutenção do Sono/epidemiologia , Cobertura Universal do Seguro de Saúde/estatística & dados numéricos , Adulto Jovem
8.
Psychol Med ; 41(8): 1751-61, 2011 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-21134315

RESUMO

BACKGROUND: The aim was to examine barriers to initiation and continuation of treatment among individuals with common mental disorders in the US general population. METHOD: Respondents in the National Comorbidity Survey Replication with common 12-month DSM-IV mood, anxiety, substance, impulse control and childhood disorders were asked about perceived need for treatment, structural barriers and attitudinal/evaluative barriers to initiation and continuation of treatment. RESULTS: Low perceived need was reported by 44.8% of respondents with a disorder who did not seek treatment. Desire to handle the problem on one's own was the most common reason among respondents with perceived need both for not seeking treatment (72.6%) and for dropping out of treatment (42.2%). Attitudinal/evaluative factors were much more important than structural barriers both to initiating (97.4% v. 22.2%) and to continuing (81.9% v. 31.8%) of treatment. Reasons for not seeking treatment varied with illness severity. Low perceived need was a more common reason for not seeking treatment among individuals with mild (57.0%) than moderate (39.3%) or severe (25.9%) disorders, whereas structural and attitudinal/evaluative barriers were more common among respondents with more severe conditions. CONCLUSIONS: Low perceived need and attitudinal/evaluative barriers are the major barriers to treatment seeking and staying in treatment among individuals with common mental disorders. Efforts to increase treatment seeking and reduce treatment drop-out need to take these barriers into consideration as well as to recognize that barriers differ as a function of sociodemographic and clinical characteristics.


Assuntos
Acessibilidade aos Serviços de Saúde/estatística & dados numéricos , Serviços de Saúde Mental/estatística & dados numéricos , Adolescente , Adulto , Idoso , Feminino , Pesquisas sobre Atenção à Saúde , Humanos , Masculino , Transtornos Mentais/epidemiologia , Transtornos Mentais/psicologia , Transtornos Mentais/terapia , Pessoa de Meia-Idade , Cooperação do Paciente/estatística & dados numéricos , Fatores Socioeconômicos , Estados Unidos/epidemiologia , Adulto Jovem
9.
Br J Psychiatry ; 194(5): 411-7, 2009 05.
Artigo em Inglês | MEDLINE | ID: mdl-19407270

RESUMO

BACKGROUND: Studies of the impact of mental disorders on educational attainment are rare in both high-income and low- and middle-income (LAMI) countries. AIMS: To examine the association between early-onset mental disorder and subsequent termination of education. METHOD: Sixteen countries taking part in the World Health Organization World Mental Health Survey Initiative were surveyed with the Composite International Diagnostic Interview (n=41 688). Survival models were used to estimate associations between DSM-IV mental disorders and subsequent non-attainment of educational milestones. RESULTS: In high-income countries, prior substance use disorders were associated with non-completion at all stages of education (OR 1.4-15.2). Anxiety disorders (OR=1.3), mood disorders (OR=1.4) and impulse control disorders (OR=2.2) were associated with early termination of secondary education. In LAMI countries, impulse control disorders (OR=1.3) and substance use disorders (OR=1.5) were associated with early termination of secondary education. CONCLUSIONS: Onset of mental disorder and subsequent non-completion of education are consistently associated in both high-income and LAMI countries.


Assuntos
Transtornos Mentais/epidemiologia , Evasão Escolar , Adolescente , Adulto , Idade de Início , Criança , Efeitos Psicossociais da Doença , Manual Diagnóstico e Estatístico de Transtornos Mentais , Escolaridade , Métodos Epidemiológicos , Humanos , Instituições Acadêmicas/estatística & dados numéricos , Evasão Escolar/psicologia , Evasão Escolar/estatística & dados numéricos , Universidades/estatística & dados numéricos
10.
Psychol Med ; 39(1): 137-47, 2009 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-18423074

RESUMO

BACKGROUND: Little is known about the effects of adult attention deficit hyperactivity disorder (ADHD) on work performance or accidents-injuries.MethodA survey was administered in 2005 and 2006 to employees of a large manufacturing firm to assess the prevalence and correlates of adult ADHD. Respondents (4,140 in 2005, 4,423 in 2006, including 2,656 in both surveys) represented 35-38% of the workforce. ADHD was assessed with the World Health Organization (WHO) Adult ADHD Self-Report Scale (ASRS), a validated screening scale for DSM-IV adult ADHD. Sickness absence, work performance and workplace accidents-injuries were assessed with the WHO Health and Work Performance Questionnaire (HPQ). RESULTS: The estimated current prevalence (standard error) of DSM-IV ADHD was 1.9% (0.4). ADHD was associated with a 4-5% reduction in work performance (chi12=9.1, p=0.001), a 2.1 relative-odds of sickness absence (chi12=6.2, p=0.013), and a 2.0 relative-odds of workplace accidents-injuries (chi12=5.1, p=0.024). The human capital value (standard error) of the lost work performance associated with ADHD totaled USD 4,336 (676) per worker with ADHD in the year before interview. No data were available to monetize other workplace costs of accidents-injuries (e.g. destruction of equipment). Only a small minority of workers with ADHD were in treatment. CONCLUSIONS: Adult ADHD is a significantly impairing condition among workers. Given the low rate of treatment and high human capital costs, in conjunction with evidence from controlled trials that treatment can reduce ADHD-related impairments, ADHD would seem to be a good candidate for workplace trials that evaluate treatment cost-effectiveness from the employer's perspective.


Assuntos
Transtorno do Deficit de Atenção com Hiperatividade/economia , Transtorno do Deficit de Atenção com Hiperatividade/epidemiologia , Avaliação de Desempenho Profissional/estatística & dados numéricos , Local de Trabalho/economia , Local de Trabalho/psicologia , Absenteísmo , Acidentes de Trabalho/economia , Acidentes de Trabalho/psicologia , Adulto , Transtorno do Deficit de Atenção com Hiperatividade/psicologia , Comorbidade , Custos e Análise de Custo , Estudos Transversais , Avaliação de Desempenho Profissional/métodos , Feminino , Humanos , Indústrias/economia , Indústrias/estatística & dados numéricos , Masculino , Programas de Rastreamento/economia , Programas de Rastreamento/métodos , Programas de Rastreamento/estatística & dados numéricos , Pessoa de Meia-Idade , Saúde Ocupacional/estatística & dados numéricos , Prevalência , Licença Médica/economia , Licença Médica/estatística & dados numéricos , Inquéritos e Questionários , Estados Unidos/epidemiologia
11.
Psychol Med ; 39(8): 1365-77, 2009 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-19046473

RESUMO

BACKGROUND: Although mental disorders have been shown to predict subsequent substance disorders, it is not known whether substance disorders could be cost-effectively prevented by large-scale interventions aimed at prior mental disorders. Although experimental intervention is the only way to resolve this uncertainty, a logically prior question is whether the associations of mental disorders with subsequent substance disorders are strong enough to justify mounting such an intervention. We investigated this question in this study using simulations to estimate the number of substance disorders that might be prevented under several hypothetical intervention scenarios focused on mental disorders. METHOD: Data came from the National Comorbidity Survey Replication (NCS-R), a nationally representative US household survey that retrospectively assessed lifetime history and age of onset of DSM-IV mental and substance disorders. Survival analysis using retrospective age-of-onset reports was used to estimate associations of mental disorders with subsequent substance dependence. Simulations based on the models estimated effect sizes in several hypothetical intervention scenarios. RESULTS: Although successful intervention aimed at mental disorders might prevent some proportion of substance dependence, the number of cases of mental disorder that would have to be treated to prevent a single case of substance dependence is estimated to be so high that this would not be a cost-effective way to prevent substance dependence (in the range 76-177 for anxiety-mood disorders and 40-47 for externalizing disorders). CONCLUSIONS: Treatment of prior mental disorders would not be a cost-effective way to prevent substance dependence. However, prevention of substance dependence might be considered an important secondary outcome of interventions for early-onset mental disorders.


Assuntos
Alcoolismo/epidemiologia , Alcoolismo/prevenção & controle , Drogas Ilícitas , Transtornos Mentais/epidemiologia , Transtornos Mentais/prevenção & controle , Transtornos Relacionados ao Uso de Substâncias/epidemiologia , Transtornos Relacionados ao Uso de Substâncias/prevenção & controle , Adolescente , Adulto , Idade de Início , Alcoolismo/economia , Alcoolismo/reabilitação , Transtornos de Ansiedade/economia , Transtornos de Ansiedade/epidemiologia , Transtornos de Ansiedade/prevenção & controle , Transtornos de Ansiedade/reabilitação , Transtorno do Deficit de Atenção com Hiperatividade/economia , Transtorno do Deficit de Atenção com Hiperatividade/epidemiologia , Transtorno do Deficit de Atenção com Hiperatividade/prevenção & controle , Transtorno do Deficit de Atenção com Hiperatividade/reabilitação , Transtornos de Deficit da Atenção e do Comportamento Disruptivo/economia , Transtornos de Deficit da Atenção e do Comportamento Disruptivo/epidemiologia , Transtornos de Deficit da Atenção e do Comportamento Disruptivo/prevenção & controle , Transtornos de Deficit da Atenção e do Comportamento Disruptivo/reabilitação , Causalidade , Comorbidade , Simulação por Computador , Transtorno da Conduta/epidemiologia , Transtorno da Conduta/prevenção & controle , Transtorno da Conduta/psicologia , Transtorno da Conduta/reabilitação , Análise Custo-Benefício , Estudos Transversais , Feminino , Inquéritos Epidemiológicos , Humanos , Controle Interno-Externo , Masculino , Transtornos Mentais/economia , Transtornos Mentais/reabilitação , Transtornos do Humor/economia , Transtornos do Humor/epidemiologia , Transtornos do Humor/prevenção & controle , Transtornos do Humor/reabilitação , Probabilidade , Estudos Retrospectivos , Fatores de Risco , Transtornos Relacionados ao Uso de Substâncias/economia , Transtornos Relacionados ao Uso de Substâncias/reabilitação , Análise de Sobrevida , Resultado do Tratamento , Adulto Jovem
12.
Neurology ; 70(7): 538-47, 2008 Feb 12.
Artigo em Inglês | MEDLINE | ID: mdl-18268246

RESUMO

OBJECTIVE: To assess and compare the extent to which comorbid conditions explain the role disability associated with migraine and other severe headaches. METHODS: A probability sample of US adults (n = 5,692) was interviewed. Presence of headaches, other chronic pain conditions, and chronic physical conditions was assessed in a structured interview administered by trained interviewers. Diagnostic criteria for migraine were based on the International Headache Society classification. Mental disorders were ascertained with the Composite International Diagnostic Interview that collected diagnostic criteria according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition. Role disability was assessed with World Health Organization Disability Assessment Schedule questions about days out of role and days with impaired role functioning. RESULTS: Eighty-three percent of migraineurs and 79% of persons with other severe types of headache had some form of comorbidity. Compared with headache-free subjects, migraineurs were at significantly increased risk for mental disorders (odds ratio [OR] 3.1), other pain conditions (OR 3.3), and physical diseases (OR 2.1). Compared with headache-free subjects, persons with nonmigraine headache were also at significantly increased risk for mental disorders (OR 2.0), other pain conditions (OR 3.5), and physical diseases (OR 1.7). Migraineurs experienced role disability on 25.2% of the last 30 days compared with 17.6% of the days for persons with nonmigraine headaches and 9.7% of the days for persons without headache. Comorbid conditions explained 65% of the role disability associated with migraine and all of the role disability associated with other severe headaches. CONCLUSIONS: Comorbidity is an important factor in understanding disability among persons with headache.


Assuntos
Efeitos Psicossociais da Doença , Avaliação da Deficiência , Transtornos da Cefaleia/epidemiologia , Atividades Cotidianas/psicologia , Adolescente , Adulto , Doença Crônica/epidemiologia , Comorbidade , Coleta de Dados , Feminino , Humanos , Masculino , Transtornos Mentais/epidemiologia , Pessoa de Meia-Idade , Transtornos de Enxaqueca/epidemiologia , Dor Intratável/epidemiologia , Prevalência , Estados Unidos/epidemiologia
13.
Acta Psychiatr Scand Suppl ; (420): 8-20, 2004.
Artigo em Inglês | MEDLINE | ID: mdl-15128383

RESUMO

OBJECTIVE: The European Study of Epidemiology of Mental Disorders (ESEMeD) project was designed to evaluate the prevalence, the impact and the treatment patterns in Europe. This paper presents an overview of the methods implemented in the project. METHOD: ESEMeD is a cross-sectional study in a representative sample of 21 425 adults, 18 or older, from the general population of Belgium, France, Germany, Italy, the Netherlands and Spain. The Composite International Diagnostic Interview (WMH-CIDI) was administered by home interviews from January 2001 to August 2003 using Computer Assisted Personal Interview (CAPI) technology. Data quality was controlled to ensure reliability and validity of the information obtained. RESULTS: Response rate varied from 78.6% in Spain to 45.9% in France. Less than 4% of the individuals had errors in the checking procedures performed. CONCLUSION: The sampling methodologies, comprehensive psychiatric instruments and quality control procedures used have rendered the ESEMeD database a unique and important source of information about the prevalence, the disability burden and unmet medical needs of mental disorders within Europe.


Assuntos
Métodos Epidemiológicos , Cooperação Internacional , Transtornos Mentais/epidemiologia , Estudos de Amostragem , Adolescente , Adulto , Idoso , Efeitos Psicossociais da Doença , Estudos Transversais , Europa (Continente)/epidemiologia , Feminino , Humanos , Entrevista Psicológica , Masculino , Pessoa de Meia-Idade , Prevalência , Reprodutibilidade dos Testes , Inquéritos e Questionários
14.
Int J Methods Psychiatr Res ; 11(2): 55-67, 2002.
Artigo em Inglês | MEDLINE | ID: mdl-12459795

RESUMO

The European Study of the Epidemiology of Mental Disorders (ESEMeD/MHEDEA 2000) is a new cross-sectional study investigating the prevalence and the associated factors of mental disorders, as well as their effect on health-related quality of life and the use of services in six European countries. This paper describes the rationale, methods and the plan for the analysis of the project. A total of 22,000 individuals representative of the non-institutionalized population aged 18 and over from Belgium, France, Germany, Italy, the Netherlands and Spain are being interviewed in their homes. Trained interviewers use a computer-assisted personal interview (CAPI) including the most recent version of the Composite International Diagnostic Interview (CIDI, 2000), a well-established epidemiological survey for assessing mental disorders. This is the first international study using the standardized up-to-date methodology for epidemiological assessment. Sizeable differences in prevalence, impact and level of need that is met by the health services are expected. The analysis of these differences should facilitate the monitoring of ongoing mental health reform initiatives in Europe and provide new research hypotheses.


Assuntos
Pesquisas sobre Atenção à Saúde/estatística & dados numéricos , Transtornos Mentais/diagnóstico , Adolescente , Adulto , Idoso , Comparação Transcultural , Estudos Transversais , Coleta de Dados , Europa (Continente)/epidemiologia , Pesquisas sobre Atenção à Saúde/normas , Necessidades e Demandas de Serviços de Saúde , Humanos , Entrevista Psicológica , Transtornos Mentais/epidemiologia , Serviços de Saúde Mental/estatística & dados numéricos , Pessoa de Meia-Idade , Pacientes Ambulatoriais/estatística & dados numéricos , Determinação da Personalidade/estatística & dados numéricos , Pessoas com Deficiência Mental/estatística & dados numéricos , Prevalência , Escalas de Graduação Psiquiátrica/estatística & dados numéricos , Testes Psicológicos , Qualidade de Vida , Fatores de Risco , Inquéritos e Questionários
15.
Ann Allergy Asthma Immunol ; 87(4): 289-95, 2001 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-11686420

RESUMO

BACKGROUND: Although quality of life studies suggest that allergic rhinitis has a substantial impact on work impairment, national survey estimates of the magnitude of this impairment have varied widely. Retrospective recall bias is likely to be a major cause of this variability. OBJECTIVE: This study used a nationally representative daily diary sample to obtain prospective data that improve on previous estimates of the work impairment because of allergic rhinitis. METHODS: The MacArthur Foundation National Survey of Daily Experience is a daily diary survey that included a nationally representative subsample of 739 employed people, each of whom provided daily reports on work performance for 1 randomly assigned week of the calendar year. National Allergy Bureau monitoring station data were merged with the survey data to study the association of time-space variation in pollen/mold exposure with impaired daily work quality and quantity. RESULTS: National Allergy Bureau pollen/mold counts are significantly related to work impairments only among respondents with self-reported allergic rhinitis. The average estimated monthly salary-equivalent work impairment costs associated with pollen/mold exposure for each allergy sufferer is between $109 and $156, with an annualized national projection of between $5.4 billion and $7.7 billion. CONCLUSIONS: The extent to which these costs can be recovered by increasing the proportion of allergy sufferers who are successfully treated remains unknown and can only be evaluated definitively in effectiveness trials.


Assuntos
Alérgenos/efeitos adversos , Fungos/imunologia , Doenças Profissionais/economia , Pólen/efeitos adversos , Rinite Alérgica Perene/economia , Adulto , Fatores Etários , Efeitos Psicossociais da Doença , Custos e Análise de Custo , Demografia , Escolaridade , Custos de Saúde para o Empregador , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doenças Profissionais/epidemiologia , Doenças Profissionais/etiologia , Exposição Ocupacional/economia , Prevalência , Estudos Prospectivos , Rinite Alérgica Perene/epidemiologia , Rinite Alérgica Perene/etiologia , Fatores de Risco , Fatores Sexuais , Estados Unidos/epidemiologia , Carga de Trabalho
16.
Neuropsychobiology ; 43(3): 150-62, 2001.
Artigo em Inglês | MEDLINE | ID: mdl-11287794

RESUMO

Epidemiological studies clearly indicate that posttraumatic stress disorder (PTSD) is becoming a major health concern worldwide even if still poorly recognized and not well treated. PTSD commonly co-occurs with other psychiatric disorders, and several symptoms overlap with major depressive disorders, anxiety disorders and substance abuse; this may contribute to diagnostic confusion and underdiagnosis. This anxiety disorder provokes significant occupational, psychiatric, medical and psychosocial disability, and its consequences are enormously costly, not only to the survivors and their families, but also to the health care system and society. Work impairment associated with PTSD is very similar to the amount of work impairment associated with major depression. The pathophysiology of PTSD is multifactorial and involves dysregulation of the serotonergic as well as the noradrenergic system. A rational therapeutic approach should normalize the specific psychobiological alterations associated with PTSD. This can be achieved through the use of antidepressant drugs, mainly of those that potentiate serotonergic mechanisms. Recent double-blind placebo-controlled studies report the efficacy of selective serotonin reuptake inhibitors. Several cognitive-behavioral and psychosocial treatments have also been reported to be efficacious and could be considered when treating PTSD patients.


Assuntos
Antidepressivos/uso terapêutico , Transtornos de Estresse Pós-Traumáticos , Ensaios Clínicos como Assunto , Comorbidade , Análise Custo-Benefício , Diagnóstico Diferencial , Custos de Medicamentos , Humanos , Incidência , Escalas de Graduação Psiquiátrica , Psicoterapia , Qualidade de Vida , Receptores de Serotonina/fisiologia , Fatores de Risco , Comportamento Social , Condições Sociais , Transtornos de Estresse Pós-Traumáticos/diagnóstico , Transtornos de Estresse Pós-Traumáticos/epidemiologia , Transtornos de Estresse Pós-Traumáticos/patologia , Transtornos de Estresse Pós-Traumáticos/psicologia
17.
J Occup Environ Med ; 43(1): 2-9, 2001 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-11201765

RESUMO

This article discusses the impact of depression on work productivity and the potential for improved work performance associated with effective treatment. We undertook a review of the literature by means of a computer search using the following key terms: cost of illness, work loss, sickness absence, productivity, performance, and disability. Published works were considered in four categories: (1) naturalistic cross-sectional studies that found greater self-reported work impairment among depressed workers; (2) naturalistic longitudinal studies that found a synchrony of change between depression and work impairment; (3) uncontrolled treatment studies that found reduced work impairment with successful treatment; and (4) controlled trials that usually, but not always, found greater reduction in work impairment among treated patients. Observational data suggest that productivity gains following effective depression treatment could far exceed direct treatment costs. Randomized effectiveness trials are needed before we can conclude definitively that depression treatment results in productivity improvements sufficient to offset direct treatment costs.


Assuntos
Absenteísmo , Transtorno Depressivo/economia , Transtorno Depressivo/terapia , Indenização aos Trabalhadores , Efeitos Psicossociais da Doença , Análise Custo-Benefício , Pessoas com Deficiência , Humanos , Satisfação no Emprego , Carga de Trabalho
18.
J Occup Environ Med ; 43(1): 56-63, 2001 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-11201770

RESUMO

In an attempt to document a broader spectrum of the benefits of their pharmaceutical products, drug companies increasingly seek to include productivity claims in their promotional campaigns. We describe the existing regulatory framework of the Food and Drug Administration (FDA) for considering productivity claims, distinguishing between the traditional "substantial evidence" standard and the "competent and reliable scientific evidence" standard. But the notion of competent and reliable scientific evidence may itself be problematic, even when it is the appropriate regulatory standard, because there exists no consistent measurement approach across diseases, workplaces, jobs, and worker capabilities that is widely accepted in this emerging area of health outcomes research. We examine the various measurement approaches that have been used to quantify the impact of illness and its treatment on workplace productivity, and we describe some of the shortcomings associated with each alternative. This discussion highlights the possible difficulties faced by the FDA in reviewing productivity-based promotional claims. Finally, we suggest possible strategies for furthering this field of investigation.


Assuntos
Absenteísmo , Publicidade/legislação & jurisprudência , Indústria Farmacêutica , Saúde Ocupacional , Controle de Custos , Custos de Cuidados de Saúde , Nível de Saúde , Humanos , Avaliação de Resultados em Cuidados de Saúde , Formulação de Políticas , Política Pública , Reprodutibilidade dos Testes , Estados Unidos , United States Food and Drug Administration , Local de Trabalho/economia
19.
Health Serv Res ; 36(6 Pt 1): 987-1007, 2001 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-11775672

RESUMO

OBJECTIVE: To identify the number of people in the United States with untreated serious mental illness (SMI) and the reasons for their lack of treatment. DATA SOURCE/STUDY DESIGN: The National Comorbidity Survey; cross-sectional, nationally representative household survey. DATA COLLECTION: An operationalization of the SMI definition set forth in the Alcohol, Drug Abuse, and Mental Health Administration Reorganization Act identified individuals with SMI in the 12 months prior to the interview. The presence of SMI then was related to the use of mental health services in the past 12 months. PRINCIPAL FINDINGS: Of the 6.2 percent of respondents who had SMI in the year prior to interview, fewer than 40 percent received stable treatment. Young adults and those living in nonrural areas were more likely to have unmet needs for treatment. The majority of those who received no treatment felt that they did not have an emotional problem requiring treatment. Among those who did recognize this need, 52 percent reported situational barriers, 46 percent reported financial barriers, and 45 percent reported perceived lack of effectiveness as reasons for not seeking treatment. The most commonly reported reason both for failing to seek treatment (72 percent) and for treatment dropout (58 percent) was wanting to solve the problem on their own. CONCLUSIONS: Although changes in the financing of services are important, they are unlikely by themselves to eradicate unmet need for treatment of SMI. Efforts to increase both self-recognition of need for treatment and the patient centeredness of care also are needed.


Assuntos
Acessibilidade aos Serviços de Saúde/estatística & dados numéricos , Transtornos Mentais/epidemiologia , Transtornos Mentais/terapia , Serviços de Saúde Mental/estatística & dados numéricos , Aceitação pelo Paciente de Cuidados de Saúde/estatística & dados numéricos , Adolescente , Adulto , Distribuição por Idade , Fatores Etários , Comorbidade , Estudos Transversais , Emprego/estatística & dados numéricos , Pesquisas sobre Atenção à Saúde , Acessibilidade aos Serviços de Saúde/normas , Humanos , Modelos Logísticos , Transtornos Mentais/etiologia , Transtornos Mentais/psicologia , Serviços de Saúde Mental/normas , Pessoa de Meia-Idade , Análise Multivariada , Avaliação das Necessidades , Aceitação pelo Paciente de Cuidados de Saúde/psicologia , Pacientes Desistentes do Tratamento/psicologia , Pacientes Desistentes do Tratamento/estatística & dados numéricos , Assistência Centrada no Paciente , Prevalência , Qualidade da Assistência à Saúde , Características de Residência , Fatores de Risco , Fatores Socioeconômicos , Inquéritos e Questionários , Estados Unidos/epidemiologia
20.
JAMA ; 283(16): 2135-42, 2000 Apr 26.
Artigo em Inglês | MEDLINE | ID: mdl-10791506

RESUMO

CONTEXT: The success and simplicity of the 1994 national "Back to Sleep" campaign to reduce sudden infant death syndrome provides an opportunity to study which elements determine whether a behavior will change in the desired direction in response to a public health intervention. OBJECTIVE: To examine sociodemographic characteristics, motivation, and message exposure to ascertain which factors influenced a caregiver's choice of infant sleep position after implementation of the campaign. DESIGN: Annual nationally representative telephone surveys conducted between 1994 and 1998. SETTING: The 48 contiguous United States. PARTICIPANTS: Nighttime caregivers of infants born within the 7 months prior to interview between 1994 and 1998. Approximately 1000 interviews were conducted each year. MAIN OUTCOME MEASURES: The position the infant was usually placed in for sleep, sleep position recommendations received from specific sources, and reasons reported for position choice. RESULTS: Between 1994 and 1998, prone placement declined from 44% to 17% among white infants and from 53% to 32% among black infants. Supine placement increased from 27% to 58% among white infants and from 17% to 31% among black infants. During this period, reports of supine recommendations from at least 1 source doubled from 38% to 79%. From 1995 to 1998, 86% of caregivers who placed the infant prone reported receiving only nonprone recommendations. Infant comfort was given as a reason for prone placement by 82% of these caregivers. In multivariate analysis, physician recommendation of "supine not prone" had the strongest influence and was associated with decreased prone placement (odds ratio [OR], 0.25 [95% confidence interval [CI], 0.16-0.39]) and increased supine placement (OR, 3.37 [95% CI, 2.38-4.76]). Recommendations from all 4 sources (the physician, neonatal nurse, reading materials, and radio/television) further increased the probability of supine placement (OR, 6.01 [95% CI, 4.57-7.90]). Other factors independently associated with increased prone and decreased supine placement included maternal black race, parity of more than 1, and living in a southern or mid-Atlantic state. CONCLUSIONS: According to our study, as of 1998, approximately one fifth of infants were still placed prone, and only half were placed supine. Recommendations of supine placement during infancy by physicians at well-baby checks and by neonatal nursery staff and print and broadcast media have increased the proportion of infants placed supine. Caregiver beliefs regarding perceived advantages of prone sleeping should be addressed to attain further reduction in prone placement.


Assuntos
Cuidado do Lactente/tendências , Sono , Morte Súbita do Lactente/prevenção & controle , Decúbito Dorsal , Comportamento de Escolha , Coleta de Dados , Promoção da Saúde , Humanos , Lactente , Cuidado do Lactente/psicologia , Cuidado do Lactente/estatística & dados numéricos , Modelos Logísticos , Análise Multivariada , Decúbito Ventral , Fatores Socioeconômicos , Estados Unidos/epidemiologia
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