The Assessment of Awareness and Attitudes About the Use of Denture Adhesives Amongst Dental Practitioners in Northern Maharashtra: A Delphi Technique.

AIM: The goal of this research was to facilitate dialogue and interaction among a group of dental practitioners about their views on denture adhesives, with the objective of reaching a collective consensus through the application of the Delphi Method. METHODS: This investigation employed the Delphi Technique, involving multiple rounds of questionnaires sent to a panel of experts. The objective was to establish a consensus (defined as over 70% agreement) or to explore the different viewpoints on the subject. A comprehensive Delphi questionnaire comprising 22 items was distributed to the Dental Practitioners. The questionnaire covered five key areas concerning denture adhesives: (1) overall perceptions; (2) the role in the development of clinical conditions; (3) specific applications and potential misuses; (4) their importance in denture services, including educating patients about denture adhesives; and (5) a general assessment of their clinical applications. RESULTS: All 31 panellists, chosen randomly, unanimously agreed to participate, with each of them actively involved in all three rounds of the survey. The panellists reached a consensus and definitively concluded that denture adhesives (1) are beneficial for enhancing the fit and comfort of the prosthesis and are not used to mask the underlying denture problems; (2) cause diseases such as denture stomatitis, candidiasis, and resorption of alveolar bone; (3) have the potential for increasing retention, function, and reducing patient anxiety. However, the panellists did not achieve a consensus on whether denture adhesives cause nausea and gagging in the patients; (4) education is very important for patients with both ill-fitting and well-fitting dentures; (5) are a beneficial adjunct to dentists when fabricating dentures. CONCLUSION: The expert panel of distinguished dental practitioners determined that denture adhesives play a valuable supportive role in the field of denture prosthetics, serving important functions during both the creation and post-insertion stages of dentures.

Simple and Cost-effective Synthesis of a Rare-earth Free Long Afterglow Phosphor for Dark Visual Markings.

Materials with long afterglow (LAG) became very renowned in the field of luminescence due to their high ability to store energy. However, the development of LAG phosphors is mostly dependent on rare-earth activators, which are commercially expensive due to their limited availability across the world. On the other hand, LAG phosphors that are not based on rare-earth and are developed as an alternative cannot compete with existing rare-earth LAG phosphors. Copper-doped zinc sulfide (ZnS:Cu) phosphor developed long ago has considerable afterglow, but its development has been too tedious, and expensive, and contains usage of toxic gasses such as H2S, CS2, etc. and most of the literature refers to the cubic phase of ZnS. To overcome these issues and simplify the process, we have developed a cost-effective approach to synthesize the hexagonal phase of ZnS, without the involvement of hazardous gases. This is one of the very few reports that highlights the appearance of LAG phenomenon from the hexagonal ZnS:Cu phosphor system. Structural, morphological, and optical studies of the developed ZnS:Cu LAG phosphor have been carried out. The phosphor showed a strong green photoluminescence at 515 nm and an afterglow duration of ~ 1 h useful for specific applications of visual markings in dark conditions. The thermoluminescence spectrum shows a broad and intense glow peak at 377.15 K that indicates the electron trap depth to be at 0.75 eV, supporting our afterglow results.

Yoga: A Natural Solution to Decrease Disease Burden in Children of MTHFR Deficient Parents.

Introduction: MTHFR being a key regulatory enzyme of 1-carbon metabolism pathway serves critical function of generation of SAM, replenishment of glutathione and nucleotide synthesis and finally methylation of the bio molecules. MTHFR gene mutation is a rare au-tosomal recessive inborn error of metabolism and presents with severe hyperhomocysteinemia. MTHFR polymorphisms on the other hand are commonly encountered of which two 677 C>T and 1298 A>C have been most widely studied and reported to increase the vulnerability to neural tube defects, congenital heart disease, various neuropsychiatric disorders like autism spectrum diseases and attention deficit hyperactiv-ity disease, cleft lip/ palate, acute leukaemia, cardiovascular diseases, occlusive vascular disease in children. Methods: We conducted this prospective clinical trial to examine whether yoga practice can up regulate MTHFR gene expression. Considering the prevalence of MTHFR polymorphism, varied spectrum of its implications in disease causation including male infertility, we conducted the trial involving 30 infertile men who underwent 3 weeks of supervised YBLI. Pre and post intervention assessment of the blood and semen sample was done to see the effects. Results: We have found more than fivefold up-regulation in the expression of MTHFR gene with significant reduction of seminal free radical levels after 3 weeks of yoga practice. Interestingly we noticed significantly higher MTHFR polymorphic variants in infertile male patients compared to healthy fertile controls. Conclusion: MTHFR polymorphisms are also independently associated with many paediatric diseases. Diagnosing MTHFR deficiency in children is a challenging job and requires high index of suspicion and continuous vigilance. Yoga based lifestyle may be adopted both by parents planning conception and also by adolescent children who are sufferers of this condition to halt the consequences of mild to moderate MTHFR deficiency.

IMPLICATION OF THREAT FACTORS AND PREEXISTING DISORDERS IN DIFFERENT ISCHEMIC STROKE SUBGROUPS IN ELDERLY PEOPLE: A SYSTEMATIC STUDY.

Ischemic stroke is a major health issue, especially for the older population and it may have severe effects. Stroke diagnosis and treatment have advanced over the last 20 years, which has resulted in considerable reductions in death, long-term impairment, and the need for institutional care. Younger age groups have seen the majority of trials for acute, interventional, and preventive therapy. The purpose of this research was to identify distinct subgroups of older people who had suffered an ischemic stroke and examine the role that risk factors and previous illnesses played in their development. Ischemic stroke risk factors varied by age, gender and exhibited their own unique features. Smoking, cholesterol, and psychological/emotional stress were shown to have the greatest prevalence (p<0.06) among stroke patients aged 45-60. Smoking is associated with a significant (p<0.07) decline in health in elderly people. Our results imply that there are significant patterns of risk factors and preexisting illnesses among the various subgroups of older people who have had an ischemic stroke. Atherosclerotic (large-artery) and cardio embolic (small-artery) ischemic strokes were shown to be the most prevalent among the elderly. Strong associations were found between these subtypes and other risk factors, including higher cholesterol, diabetes, high blood pressure, and atrial fibrillation. This research emphasizes the need for individualized preventative methods and therapeutic therapy, as well as the need to recognize the variability of ischemic stroke in the elderly.

Assessment of thermal distribution through an inclined radiative-convective porous fin of concave profile using generalized residual power series method (GRPSM).

The thermal distribution in a convective-radiative concave porous fin appended to an inclined surface has been examined in this research. The equation governing the temperature and heat variation in fin with internal heat generation is transformed using non-dimensional variables, and the resulting partial differential equation (PDE) is tackled using an analytical scheme, generalized residual power series method (GRPSM). Moreover, a graphical discussion is provided to examine the consequence of diverse non-dimensional variables including the parameters of convection-conduction, ambient temperature, radiation, heat generation, and porosity effect on the thermal field of the fin. Also, a graph is plotted to analyze the variations in unsteady temperature gradient using the finite difference method (FDM) and generalized residual power series method (GRPSM). The major result of this investigation unveils that as the convection-conduction parameter scale upsurges, the distribution of temperature in the fin diminishes. For the heat-generating parameter, the thermal distribution inside the fin increases.

A Low-Cost Multistage Cascaded Adaptive Filter Configuration for Noise Reduction in Phonocardiogram Signal.

Phonocardiogram (PCG), the graphic recording of heart signals, is analyzed to determine the cardiac mechanical function. In the recording of PCG signals, the major problem encountered is the corruption by surrounding noise signals. The noise-corrupted signal cannot be analyzed and used for advanced processing. Therefore, there is a need to denoise these signals before being employed for further processing. Adaptive Noise Cancellers are best suited for signal denoising applications and can efficiently recover the corrupted PCG signal. This paper introduces an optimal adaptive filter structure using a Sign Error LMS algorithm to estimate a noise-free signal with high accuracy. In the proposed filter structure, a noisy signal is passed through a multistage cascaded adaptive filter structure. The number of stages to be cascaded and the step size for each stage are adjusted automatically. The proposed Variable Stage Cascaded Sign Error LMS (SELMS) adaptive filter model is tested for denoising the fetal PCG signal taken from the SUFHS database and corrupted by Gaussian and colored pink noise signals of different input SNR levels. The proposed filter model is also tested for pathological PCG signals in the presence of Gaussian noise. The simulation results prove that the proposed filter model performs remarkably well and provides 8-10 dB higher SNR values in a Gaussian noise environment and 2-3 dB higher SNR values in the presence of colored noise than the existing cascaded LMS filter models. The MSE values are improved by 75-80% in the case of Gaussian noise. Further, the correlation between the clean signal and its estimate after denoising is more than 0.99. The PSNR values are improved by 7 dB in a Gaussian noise environment and 1-2 dB in the presence of pink noise. The advantage of using the SELMS adaptive filter in the proposed filter model is that it offers a cost-effective hardware implementation of Adaptive Noise Canceller with high accuracy.

Indian Academy of Pediatrics Consensus Guidelines on Prevention and Management of Suicidal Behavior in Adolescents.

JUSTIFICATION: Suicide is an important cause of adolescent mortality and morbidity in India. As pediatricians are often the first point of contact for adolescents and their families in the healthcare system, they need guidelines to screen, assess, manage and prevent adolescent suicidal behavior to ensure survival, health and mental well-being of this vulnerable population. OBJECTIVES: To formulate guidelines to aid pediatricians for prevention and management of adolescent suicidal behavior. PROCESS: Indian Academy of Pediatrics, in association with Adolescent Health Academy, formed a multidisciplinary committee of subject experts in June, 2019 to formulate guidelines for adolescent suicide prevention and management. After a review of current scientific literature and preparation of draft guidelines, a national consultative meeting was organized on 16 August, 2019 for detailed discussions and deliberations. This was followed by refining of draft guidelines, and discussions over e-mail where suggestions were incorporated and the final document was approved. GUIDELINES: Pediatricians should screen for mental distress, mental disorders and suicidal and para-suicidal (non-suicidal self-injury) behavior during adolescent health visits. Those with suicidal behavior should be referred to a psychiatrist after providing emergency healthcare, risk assessment, immediate counselling and formulation of a safety plan. Pediatricians should partner with the community and policymakers for primary and secondary prevention of adolescent suicide.

Lime activated flyash-phosphogypsum blend as a low-cost alternative binder.

This study investigates the potential of a blended binder formulated from two industrial solid wastes viz. phosphogypsum and fly ash in combination with lime. Three mix proportions of phosphogypsum and fly ash were investigated, and the minimum lime contents required for activation were determined using the Eades and Grim pH test. The lime-fly ash-phosphogypsum blends were then cast into cubes, both in their paste form as well as mortar form, mixed with sand in the ratio of 1:3. They were cured for a period of seven days, and afterwards, their compressive strength was determined. Ordinary Portland cement and lime mortar blocks were also cast as control specimens for comparative evaluation of the strength. The optimal lime-fly ash-phosphogypsum blend was identified and used to construct a masonry prism, and the strengths of the masonry prisms were also evaluated. The optimal lime-fly ash-phosphogypsum blend mortar was also subjected to an X-ray diffraction analysis to determine the reaction products formed during hydration. The study revealed that 5% lime mixed with fly ash:phosphogypsum in the ratio of 3:1 was the optimal proportion which gave the maximum strength to the cubes. The optimal lime-fly ash-phosphogypsum blend mortar developed strength that was higher than conventional Portland cement and lime mortar. The optimal lime-fly ash-phosphogypsum blend mortar masonry prisms developed strength that was comparable to that of Portland cement mortar masonry. The X-ray diffraction analysis revealed the formation of calcium silicate hydrate minerals as well as ettringite and portlandite which were responsible for strength gain.

A Population Health Approach to Address the Burden of Congenital Heart Disease in Kerala, India.

Background: Congenital heart disease (CHD) has emerged as a leading contributor to infant mortality in many low-and middle-income countries (LMICs). We report early results of a population health program for CHD, implemented in the state of Kerala, India. Objective: Report on early results of a population-based program implementation in a LMIC to reduce mortality from CHD. Methods: We retrospectively analyzed the results of an innovative population-based program to address CHD. We devised, implemented and evaluated measures in the care continuum to address deficiencies in CHD care in Kerala, India, through structured capacity building initiatives that enabled early detection, prompt stabilization and expedited referral to a tertiary center. A comprehensive web-based application enabled real-time case registration, prioritization of treatment referrals, and tracking every child registered with CHD. Advanced pediatric heart care was delivered through a public-private partnership. Results: Early identification, referral, and treatment of infants with CHD were improved. The web-based application, 'Hridyam,' registered 502 cases in 2017 (Aug-Dec), 2190 in 2018 and 3259 in 2019; infants < 1 year of age constituted 56, 62 and 63% in these years, respectively. The number of heart operations managed through Hridyam rose from 208 to 624 and 1227 in the same years, with overall 30-day mortality of 2.4%. Overall- and CHD-related infant mortality in Kerala fell by 21.1% and 41.0%, respectively, over the same interval. Unmet challenges include lack of universal catchment and a 5% preoperative mortality rate. Conclusion: We demonstrate successful implementation of a population-based and real-time approach to reduce CHD mortality. We speculate that Hridyam has contributed to the observed decline in Kerala's IMR from 12 to 7 between 2016 and 2019. This model has potential applications for other conditions, and in other jurisdictions, especially LMICs considering building CHD capacity.

Soft & Hard Tissue Assessment around Immediate & Delayed Implants: A Clinico-Radiographical Study.

The aim of the modern dentistry is to provide the predictable treatment in short duration. Replacement of missing teeth in shorter duration helps in fulfilling patient's aesthetics and functional demands. Endosseous dental implants are predictable method for replacing missing dentition. The evolution in implant surgical techniques is focused on decreasing treatment duration, e.g. implants can be placed in fresh extraction socket. Therefore, this non-randomized clinical controlled study was designed to determine that whether the treatment outcomes obtained by short treatment duration (immediate implant) are comparable with conventional treatment options (delayed implant) by evaluating the peri-implant soft and hard tissue level, clinically and radiographically {by Cone beam computed tommography (CBCT)}. Total of 30 implants were placed in 13 patients, according to Type 1 ITI protocol (Group 1; 15 implants) and Type 4 ITI protocol (Group 2; 15 implants). Implants in each group were loaded with definitive restoration after 3 months of placement. Hard tissue parameters (marginal bone width and height and probing depth) and soft tissue parameters (width of keratinised gingiva and papillary index) were evaluated at baseline, 3 months post implant insertion and 3 months post prosthetic loading. The results showed statistically significant reduction in width of marginal bone in delayed implants as compared to immediate implants. In contrast, significant reduction in marginal bone height and width of keratinised gingiva was evident in immediate implants. Significant reduction in pocket depth (after 2nd stage surgery and 3 months post prosthetic loading) was noted around delayed implants (p<0.05). Moreover, esthetic results showed regeneration of interproximal papillae in both the groups till the end of study period. This study was concluded that both the groups showed similar results but in some aspects delayed implants was superior to immediate implants. Careful evaluation of implant placement sites before implant installation promotes optimal implant esthetics and survival outcomes.

Challenges and Special Aspects of Pulmonary Hypertension in Middle- to Low-Income Regions: JACC State-of-the-Art Review.

Challenges and special aspects related to the management and prognosis of pulmonary hypertension (PH) in middle- to low-income regions (MLIRs) range from late presentation to comorbidities, lack of resources and expertise, cost, and rare options of lung transplantation. Expert consensus recommendations addressing the specific challenges for prevention and therapy of PH in MLIRs with limited resources have been lacking. To date, 6 MLIR-PH registries containing mostly adult patients with PH exist. Importantly, the global prevalence of PH is much higher in MLIRs compared with high-income regions: group 2 PH (left heart disease), pulmonary arterial hypertension associated with unrepaired congenital heart disease, human immunodeficiency virus, or schistosomiasis are highly prevalent. This consensus statement provides selective, tailored modifications to the current PH guidelines to address the specific challenges faced in MLIRs, resulting in the first pragmatic and cost-effective consensus recommendations for PH care providers, patients, and their families.

Occurrence, sources and risk assessment of fluoroquinolones in dumpsite soil and sewage sludge from Chennai, India.

Soil and sludge are major reservoirs of organic compounds such as fluoroquinolones (FQs) which are broad-spectrum antibacterial agents. Hence, we monitored three major FQs, namely, ciprofloxacin (CIP), norfloxacin (NOR), and ofloxacin (OFL), in surface soil from two major dumpsites and dry and wet sludge from sewage treatment plants in Chennai city. The mean concentration of FQs in soil and sludge samples were 20 µg/g and 26 µg/g, respectively. Nearly 50% of the total FQs in dumpsite soil was contributed by CIP followed by NOR (32%) and OFL (13%). Similarly, CIP was the major contributor in sludge samples followed by NOR and OFL. The concentration of FQs was two folds higher in wet sludge than dry sludge most likely indicating that water solubility of these compounds might play an important role for elevated level of FQs in wet sludge. Solid waste from pharmaceutical industries, households, and sludge from wastewater treatment plants were expected to be the major source of FQs in dumpsite soil. Predicted risk assessment using soil to water migration concentrations via surface run off indicated high risk to aquatic organisms. However, risk quotient (RQ) was found less to earthworm in most of the soil samples. The findings from this study might help in future policies on disposal of household antibiotics in the solid waste stream.

Oral health behaviour, practices, status and the dental treatment needs among paliyan and pulayan tribes in India.

It is of interest to document the The Oral Health heigene data among the paliyan and pulayan tribes in India. The Paliyan and Pulayan tribes inhabit a narrow strip of Western Ghats in the hilly regions of Madurai, Dindigul, Theni, Tirunelveli and Virudhunagar districts of Tamil Nadu. Subjects aged 5yrs and above are used in this study. The WHO assessment form was used to assess the oral health status. Results show that 589 (58%) ignored the oral health problems, 225 (22.2%) relied on self-medications, 142 (14%) consulted a general physician, 35 (3.5%) had visited a dentist and the remaining 23 (2.3%) were dependent upon over the counter medications from a pharmacy. Thus, the prosthetic need was highest among the 55 + yrs age group, 36 (48.6%) required maxillary prosthesis and 21 (28.4%) required mandibular prosthesis.

Treatment seeking pathways in pediatric tuberculosis patients attending DOTS centers in urban areas of Delhi.

BACKGROUND: The treatment seeking pathways prior to initiation of Direct Observed Treatment Short-course Therapy (DOTS), provides the extent of patient and health system delays among pediatric tuberculosis (TB) patients. OBJECTIVES: The study attempted to understand the treatment seeking pathways of pediatric TB patients under revised national tuberculosis control program (RNTCP). STUDY DESIGN AND SETTING: It was a prospective observational study carried out from January 2015 to December 2015. A predesigned, pretested and semi-structured questionnaire was used to interview 141 caregivers of pediatric patients (0-14 years) at two chest clinics selected purposively. RESULTS: Thirteen different treatment seeking pathways were identified and fever was the commonest symptom (41.8%) for seeking care from 1st health facility. Median time taken from onset of symptoms to first consultation varied from 1 to 144 weeks. More than half of the study subjects were first taken to a private practitioner (64.5%) followed by a pharmacist (19.1%) and trust in provider was the commonest reason for choosing the first care-provider in 52 (41.1%), followed by easy access or convenience in 49 (34.8%). CONCLUSION: A significant delay was found in treatment initiation of patients with extra pulmonary tuberculosis (EPTB), those belonging to lower socio-economic class families, low literacy level of parents, who went to private facility first and availed more than three health facilities before diagnosis.

An instrumented object for hand exercise and assessment using a pneumatic pressure sensor.

Measurement of grip force is important for both exercise training and assessment of the hand during physical rehabilitation. The standard method uses a grip dynamometer which measures the force between the fingers and opposing thumb. The primary limitation of the grip dynamometer is the restriction of measurement to cylindrical grasps. Any deformation of the hand due to muscular or skeletal disease makes the grip dynamometer difficult or impossible to use. An alternative to the grip dynamometer is a sealed pneumatic object that can be gripped by the hand. Measurement of the internal pressure in the object can be related to the grip force. In this paper, we analyze such a pneumatic pressure sensing object for hand grip assessment and also describe an easy fabrication of the grip sensor. The instrumented object presented in this paper is designed to assess both the maximal voluntary grip forces and continuous grip force to monitor control of hand function during exercise under instruction from a therapist. Potential uses of such a pneumatic pressure sensing object for hand grip are in physical rehabilitation of patients following paralysing illnesses like stroke and spinal cord injury.

Impact of mild alkali dosage on immobilized Exiguobacterium spp. mediated cost and energy efficient sludge disintegration.

Approaches to (extracellular polymeric substance) EPS removal were studied with major aim to enhance the biodegradability and sludge solubilization. In this study, a novel approach of entrapment of bacterial strain was carried out to achieve long term activity of protease secreting bacteria Exiguobacterium sp. A mild treatment of potassium hydroxide (KOH) was applied to remove EPS which was followed by entrapment under the biological pretreatment. The efficiency of Exiguobacterium was predicted through dissolvable organic and suspended solids (SS) reduction. The maximum dissolvable organic matter released was 2300mg/L with the solubilization of 23% which was obtained for sludge without EPS (SWOE). For dissolvable organic release, SWOE showed higher final methane production of 232mL/g COD at the production rate of 16.2mL/g COD.d. The SWOE pretreatment was found to be cost effective and less energy intensive beneficial in terms of energy and cost (43.9KWh and -8.2USD) when compared to sludge with EPS (SWE) pretreatment (-177.6KWh and -91.23USD).

The WHF Roadmap for Reducing CV Morbidity and Mortality Through Prevention and Control of RHD.

Rheumatic heart disease (RHD) is a preventable non-communicable condition that disproportionately affects the world's poorest and most vulnerable. The World Heart Federation Roadmap for improved RHD control is a resource designed to help a variety of stakeholders raise the profile of RHD nationally and globally, and provide a framework to guide and support the strengthening of national, regional and global RHD control efforts. The Roadmap identifies the barriers that limit access to and uptake of proven interventions for the prevention and control of RHD. It also highlights a variety of established and promising solutions that may be used to overcome these barriers. As a general guide, the Roadmap is meant to serve as the foundation for the development of tailored plans of action to improve RHD control in specific contexts.

The World Health Organization Measles Programmatic Risk Assessment Tool-Pilot Testing in India, 2014.

Measles is a leading cause of child mortality, and reduction of child mortality is a key Millennium Development Goal. In 2014, the World Health Organization and the U.S. Centers for Disease Control and Prevention developed a measles programmatic risk assessment tool to support country measles elimination efforts. The tool was pilot tested in the State of Uttarakhand in August 2014 to assess its utility in India. The tool assessed measles risk for the 13 districts of Uttarakhand as a function of indicator scores in four categories: population immunity, surveillance quality, program delivery performance, and threat. The highest potential overall score was 100. Scores from each category were totaled to assign an overall risk score for each district. From this risk score, districts were categorized as low, medium, high, or very high risk. Of the 13 districts in Uttarakhand in 2014, the tool classified one district (Haridwar) as very high risk and three districts (Almora, Champawat, and Pauri Garhwal) as high risk. The measles risk in these four districts was largely due to low population immunity from high MCV1-MCV2 drop-out rates, low MCV1 and MCV2 coverage, and the lack of a supplementary immunization activity (SIA) within the past three years. This tool can be used to support measles elimination in India by identifying districts that might be at risk for measles outbreaks, and to guide risk mitigation efforts, including strengthening routine immunization services and implementing SIAs.

Measurement of Scientific Productivity in R&D Sector: Changing paradigm.

Scientific Productivity is a demand of policy makers for a judicious utilization of massive R&D budget allocated and utilized. A huge mass of intellectual assets is employed, which after investing manpower, infrastructure and lab consumables demand for a major outcome which contributes towards building nation's economy. Scientific productivity was only measured through publications or patents. Patents, earmarked as a strong parameter for innovation generation, where, Word Intellectual Property Organisation generated a data on applications for the top 20 offices for patents, where Australia, Brazil and Canada occupied top 3 positions. India ranked 9th with the total patent applications rising from 39762 (2010) to 42854 (2014) i.e. 15%, whereas, it contributes around 2% Patents (innovative productivity) on global scale. Many studies have come forward interestingly within scientific and academic domains in the form of measurement of scientific performance, however, development of productivity indicators and calculation of Scientific Productivity (SP) as a holistic evaluation system is a significant demand. SP, a herculean task is envisaged for productivity analysis and would submit significant factors towards fabricating an effective measurement engine in a holistic manner viable for an individual and organization, being supplementary to each other. This review projects the significance of performance measurement system in R&D through identification and standardization of key parameters. It also includes emphasis on inclusion of standardized parameters, effective for performance measurement which is applicable for scientists, technical staff as well as lab as a facility. This review aims at providing an insight to the evaluators, policy makers, and high level scientific panels to stimulate the scientific intellects on identified indicators so that their work proceeds to generate productive outcome contributing to the economic growth.