1.
Org Lett
; 3(5): 695-8, 2001 Mar 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11259039
RESUMO
[structure: see text]. The solution structure of (+)-discodermolide (1) has been determined via 1- and 2-D NMR techniques in conjunction with Monte Carlo conformational analysis. Taken together, the results demonstrate that in solution (+)-discodermolide occupies a helical conformation remarkably similar to the solid state conformation.