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1.
Environ Int ; 184: 108434, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38237506

RESUMO

Pharmaceuticals are receiving increasing attention as emerging contaminants in the aquatic environment. Herein, we investigated the occurrence of 11 antidepressants, 6 antihistamines and 4 metabolites in treated wastewater effluents, rivers, stormwater, and seawater in Hong Kong, with special focus on chirality. The average levels of ∑pharmaceuticals ranged from 0.525 to 1070 ng/L in all samples and the total annual mass load of target pharmaceuticals in the marine environment of Hong Kong was 756 kg/y. Antihistamines accounted for >80 % of ∑pharmaceuticals, with diphenhydramine and fexofenadine being predominant. The occurrence and enantiomeric profiles of brompheniramine and promethazine sulfoxide were reported in global natural waters for the first time. Among chiral pharmaceuticals, mirtazapine and fexofenadine exhibited R-preference, while others mostly exhibited S-preference, implying that the ecological risks derived from achiral data for chiral pharmaceuticals may be biased. The joint probabilistic risk assessment of fluoxetine revealed that R-fluoxetine and rac-fluoxetine presented different ecological risks from that of S-fluoxetine; Such assessment also revealed that target pharmaceuticals posed only minimal to low risks, except that diphenhydramine posed an intermediate risk. As estimated, 10 % aquatic species will be affected when the environmental level of diphenhydramine exceeds 7.40 ng/L, which was seen in 46.9 % samples. Collectively, this study highlights further investigations on the enantioselectivity of chiral pharmaceuticals, particularly on environmental behavior and ecotoxicity using local aquatic species as target organisms.


Assuntos
Fluoxetina , Terfenadina/análogos & derivados , Poluentes Químicos da Água , Fluoxetina/toxicidade , Poluentes Químicos da Água/análise , Monitoramento Ambiental , Antidepressivos , Antagonistas dos Receptores Histamínicos , Difenidramina , Medição de Risco , Rios , Preparações Farmacêuticas
2.
Mar Pollut Bull ; 189: 114719, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-36821929

RESUMO

Estuaries are unique transition zones connecting terrestrial and coastal environments and are recognized as primary conveyors for land-derived plastics to open oceans. Riverine microplastics (MPs) have been commonly investigated using sequential sampling which might not effectively reflect the actual load. In this study, sampling at eight outlets was performed during a complete tidal cycle to estimate the MP flux to the Pearl River Estuarine (PRE) using a concurrent sampling strategy. The MP abundances ranged from 2.90 ± 0.57-5.9 ± 2.27 particles/L. A remarkable difference between tides in MP abundances suggests tidal effect should not be overlooked in assessment. The MP load through the eight outlets was estimated at 304 trillion particles or 1102 tons into the PRE annually. Additionally, similar potential ecological risk assessment among eight rivers implied that environmental threats posed by less urbanized and populated rural areas on the western side have been under-evaluating for decades.


Assuntos
Estuários , Poluentes Químicos da Água , Microplásticos , Plásticos , Rios , Poluentes Químicos da Água/análise , Monitoramento Ambiental , China , Medição de Risco
3.
Medicine (Baltimore) ; 100(34): e27051, 2021 Aug 27.
Artigo em Inglês | MEDLINE | ID: mdl-34449493

RESUMO

ABSTRACT: School-based first aid interventions can contribute to the number of adults trained in first aid in the community over time but few studies have examined the effectiveness of teaching non-resuscitative first aid on knowledge, attitudes and skills. Currently, there is no consensus on the optimal content and duration of first aid training for junior secondary students. The aim of this study was to evaluated the effectiveness of a 2.5 hour introductory non-resuscitative first aid course for junior secondary students.This prospective, single-centre, pre-post study included 140 students (11-13 years old). Students completed a questionnaire on first aid knowledge, attitude towards first aid and self-confidence to perform first aid before and after a training session. Six emergency medicine physicians taught practical first aid skills training. A game-based formative assessment was undertaken where the instructors assessed small teams of students' role-playing injured classmates and first aid responders (and vice-versa) treating abrasions, ankle sprain, choking and a scald injury.Few students had prior first aid training (14%). After adjusting for student's age, sex, prior first aid training and format delivery, the course was associated with increased mean knowledge score (pre-training 53%, post-training 88%; mean difference [MD] 35%, 95% CI: 32% to 38%), positive attitudes and more confidence in performing first aid after training (all P < .001). All teams showed a good level of competency in treating simulated injuries with first aid kits.This brief non-resuscitative first aid course was associated with noticeable and valuable changes in knowledge score and self-confidence level in performing first aid. The game-based formative assessment facilitated a positive learning environment for skill competency evaluation.


Assuntos
Primeiros Socorros/métodos , Educação em Saúde/organização & administração , Serviços de Saúde Escolar/organização & administração , Adolescente , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Masculino , Estudos Prospectivos
4.
Ecotoxicol Environ Saf ; 181: 26-33, 2019 Oct 15.
Artigo em Inglês | MEDLINE | ID: mdl-31154117

RESUMO

Organic ultraviolet (UV) filters are common ingredients of personal care products and occur ubiquitously in the aquatic environment; however, little is known about their distribution in and potential effects to the marine environment. This study reports the occurrence, toxicological effects and risk assessment of eleven commonly consumed UV filters in marine surface water collected from the South China Sea (SCS) coastal region. The concentrations of UV filters ranged from

Assuntos
Organismos Aquáticos/efeitos dos fármacos , Monitoramento Ambiental/métodos , Rios/química , Água do Mar/química , Protetores Solares/análise , Poluentes Químicos da Água/análise , China , Estuários , Hong Kong , Medição de Risco , Protetores Solares/toxicidade , Poluentes Químicos da Água/toxicidade
5.
J Hazard Mater ; 371: 288-294, 2019 06 05.
Artigo em Inglês | MEDLINE | ID: mdl-30856439

RESUMO

The concentrations and spatial distribution of 14 organophosphorus flame retardants (OPFRs) and plasticizers were studied in aquatic environments of China, namely, the Pearl River Delta (PRD), South China Sea (SCS) and Yellow River Estuary (YRE), as well as Tokyo Bay (TB) in Japan. These locations were characterized by different levels of socioeconomic development and human activities. The spatial pattern of OPFRs revealed their ubiquity along the coasts of China and Japan; the concentrations ranged from 15 to 1790, 1 to 147, 253 to 1720, and 107 to 284 ng L-1 in the PRD, SCS, YRE and TB, respectively. The most frequently detected OPFR was triethyl phosphate (TEP), followed by triphenylphosphine oxide (TPPO) and tris(2-chloroethyl) phosphate (TCEP). A positive relationship (R2 = 0.668, p = 0.004) was observed between OPFR contamination and socioeconomic activity, measured by gross domestic product (GDP) per capita, for the studied cities in China and Japan. The results suggest that an increase in manufacturing and construction activities in the studied areas may aggravate coastal contamination with OPFRs. The potential threat to aquatic organisms from exposure to TCEP, a suspected carcinogen, was revealed by the hazard quotient (HQ) and probabilistic assessments. Further investigation of OPFR exposure in the aquatic environment of China is urgently required.

6.
Water Res ; 149: 607-616, 2019 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-30522053

RESUMO

Concern about the presence of chiral pharmaceuticals in the environment from wastewater discharge is mounting. In this work, the occurrence and fate of atenolol, metoprolol, venlafaxine, and chloramphenicol, including 10 different stereoisomers, were investigated in sewage and sludge from diverse treatment processes in 4 sewage treatment plants (STPs) in Hong Kong via 4 sampling campaigns over a period of 2 years. The average amounts of individual pharmaceuticals entering the STPs ranged from 4.91 g/d to 6290 g/d, with sludge carrying much lower amounts than the discharged effluent. Mass balance analysis revealed that: larger quantities of these pharmaceuticals were released during the dry seasons, biodegradation was the primary removal mechanism for atenolol and chloramphenicol, and the removal via primary sedimentation and disinfection processes was insignificant (<30%). Selectivity toward R-(+)-atenolol, S-(-)-metoprolol, and R-(-)-venlafaxine was mostly found across secondary-treated effluent samples. Sold as an enantiopure pharmaceutical in R,R-para-form, chloramphenicol was preferentially eliminated after biological process. This is the first study on the occurrence of chloramphenicol enantiomers in the aquatic environment. Ecotoxicological assessment indicated that atenolol and metoprolol could pose risks to marine fish in effluent-receiving waters (i.e., the western waters and Victoria Harbor) of Hong Kong, while R-(+)-atenolol could pose a risk to protozoans five times higher than the S-(-)-enantiomer.


Assuntos
Preparações Farmacêuticas , Poluentes Químicos da Água , Animais , Hong Kong , Medição de Risco , Estações do Ano , Esgotos , Estereoisomerismo
7.
Sci Total Environ ; 583: 421-431, 2017 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-28126280

RESUMO

A total of 211 water samples were collected from 53 key sampling points from 5-10th July 2013 at four different depths (0m, 2m, 4m, 8m) and at different sites in the Huaihe River, Anhui, China. These points monitored for 18 parameters (water temperature, pH, TN, TP, TOC, Cu, Pb, Zn, Ni, Co, Cr, Cd, Mn, B, Fe, Al, Mg, and Ba). The spatial variability, contamination sources and health risk of trace elements as well as the river water quality were investigated. Our results were compared with national (CSEPA) and international (WHO, USEPA) drinking water guidelines, revealing that Zn, Cd and Pb were the dominant pollutants in the water body. Application of different multivariate statistical approaches, including correlation matrix and factor/principal component analysis (FA/PCA), to assess the origins of the elements in the Huaihe River, identified three source types that accounted for 79.31% of the total variance. Anthropogenic activities were considered to contribute much of the Zn, Cd, Pb, Ni, Co, and Mn via industrial waste, coal combustion, and vehicle exhaust; Ba, B, Cr and Cu were controlled by mixed anthropogenic and natural sources, and Mg, Fe and Al had natural origins from weathered rocks and crustal materials. Cluster analysis (CA) was used to classify the 53 sample points into three groups of water pollution, high pollution, moderate pollution, and low pollution, reflecting influences from tributaries, power plants and vehicle exhaust, and agricultural activities, respectively. The results of the water quality index (WQI) indicate that water in the Huaihe River is heavily polluted by trace elements, so approximately 96% of the water in the Huaihe River is unsuitable for drinking. A health risk assessment using the hazard quotient and index (HQ/HI) recommended by the USEPA suggests that Co, Cd and Pb in the river could cause non-carcinogenic harm to human health.

8.
J Hazard Mater ; 292: 180-7, 2015 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-25804793

RESUMO

Organic ultraviolet (UV) filters are used widely in various personal care products and their ubiquitous occurrence in the aquatic environment has been reported in recent years. However, data on their fate and potential impacts in marine sediments is limited. This study reports the occurrence and risk assessment of eleven widely used organic UV filters in marine sediment collected in Hong Kong and Tokyo Bay. Seven of the 11 target UV filters were detected in all sediment samples (median concentrations:

Assuntos
Ecologia , Sedimentos Geológicos/química , Água do Mar , Raios Ultravioleta , Hong Kong , Japão , Medição de Risco
9.
J Hazard Mater ; 285: 389-97, 2015 Mar 21.
Artigo em Inglês | MEDLINE | ID: mdl-25528239

RESUMO

Concentrations of 23 per- and polyfluoroalkyl substances (PFASs), including new classes of PFASs, in seawater samples were investigated for their occurrence and the interaction of the ocean currents with the distribution of PFASs in the South China Sea. This study revealed that socio-economic development was associated with the PFAS contamination in coastal regions of South China. Significant correlations between concentration of total PFASs with gross domestic product (GDP) per capita and population density were found in the areas, suggesting that the influence of intense human activities in these areas may have resulted in higher PFAS contamination to the adjacent environment. Di-substituted polyfluoroalkyl phosphate (diPAP), one of the potential replacements for PFASs, was only detected in the heavily developed region, namely Pearl River Delta (PRD). Total PFAS concentrations, ranging from 195 to 4925 pg/L, were detected at 51 sampling stations of the South China Sea. The results also confirmed that PFAS contamination in the South China Sea is strongly affected by the ocean currents. In comparison to perfluoroactane sulfonate (PFOS) concentrations measured nine years ago at the same locations, the concentrations in this study were found to be two times higher. This indicated that the use and production of perfluoroalkyl sulfonates (PFSAs) has been continuing in the region.


Assuntos
Ácidos Alcanossulfônicos/análise , Fluorocarbonos/análise , Poluentes Químicos da Água/análise , China , Monitoramento Ambiental , Produto Interno Bruto , Atividades Humanas , Humanos , Oceanos e Mares , Fosfatos/análise , Densidade Demográfica , Água do Mar/análise , Movimentos da Água
10.
Water Res ; 67: 55-65, 2014 Dec 15.
Artigo em Inglês | MEDLINE | ID: mdl-25261628

RESUMO

Organic UV filters are common ingredients of personal care products (PCPs), but little is known about their distribution in and potential impacts to the marine environment. This study reports the occurrence and risk assessment of twelve widely used organic UV filters in surface water collected in eight cities in four countries (China, the United States, Japan, and Thailand) and the North American Arctic. The number of compounds detected, Hong Kong (12), Tokyo (9), Bangkok (9), New York (8), Los Angeles (8), Arctic (6), Shantou (5) and Chaozhou (5), generally increased with population density. Median concentrations of all detectable UV filters were <250 ng/L. The presence of these compounds in the Arctic is likely due to a combination of inadequate wastewater treatment and long-range oceanic transport. Principal component analysis (PCA) and two-way analysis of variance (ANOVA) were conducted to explore spatiotemporal patterns and difference in organic UV filter levels in Hong Kong. In general, spatial patterns varied with sampling month and all compounds showed higher concentrations in the wet season except benzophenone-4 (BP-4). Probabilistic risk assessment showed that 4-methylbenzylidene camphor (4-MBC) posed greater risk to algae, while benzophenone-3 (BP-3) and ethylhexyl methoxycinnamate (EHMC) were more likely to pose a risk to fishes and also posed high risk of bleaching in hard corals in aquatic recreational areas in Hong Kong. This study is the first to report the occurrence of organic UV filters in the Arctic and provides a wider assessment of their potential negative impacts in the marine environment.


Assuntos
Água Doce/química , Água do Mar/química , Protetores Solares/análise , Poluentes Químicos da Água/análise , Cromatografia Líquida de Alta Pressão , Geografia , Medição de Risco , Estatísticas não Paramétricas , Protetores Solares/efeitos adversos , Espectrometria de Massas em Tandem , Poluentes Químicos da Água/efeitos adversos
11.
Environ Monit Assess ; 186(8): 4753-65, 2014 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-24756412

RESUMO

Coal mining area is highly subject to lead (Pb) pollution from coal mining activities. Several decades of coal mining and processing practices in dozens of coal mines in the Huainan Coal Mining Area (HCMA) have led to the accumulation of massive amounts of coal gangue, which piled in dumps. In order to investigate the impacts of coal gangue dumps on Pb level in the supergene media of the HCMA, a systematic sampling campaign comprising coal gangue, soil, wheat, and earthworm samples was conducted. The average Pb content in the coal mining area soil is 24 mg/kg, which is slightly higher than the associated coal gangues (23 mg/kg) and markedly higher than reference region soil (12.6 mg/kg). Soil in the HCMA present a slight to moderate Pb contamination, which might be related to the weathering and leaching of coal gangue dumps. Lateral distribution of Pb in HCMA soil differed among individual coal mines. The soil profile distribution of Pb depends on both natural and anthropogenic contributions. Average Pb content is higher in roots than in stems, leaves, and wheat husks, while the Pb level in seeds exceeded the maximum Pb allowance for foods (Maximum Levels of Contaminants in Foods of China, GB 2762-2012). Earthworms in the selected area are significantly enriched in Pb, suggesting higher bio-available Pb level in soil in the HCMA.


Assuntos
Minas de Carvão , Monitoramento Ambiental , Chumbo/análise , Poluentes do Solo/análise , China , Poluição Ambiental/estatística & dados numéricos , Resíduos Industriais/análise , Resíduos Industriais/estatística & dados numéricos , Solo/química
12.
Water Res ; 53: 58-67, 2014 Apr 15.
Artigo em Inglês | MEDLINE | ID: mdl-24503280

RESUMO

Organic ultraviolet (UV) filters are applied widely in personal care products (PCPs), but the distribution and risks of these compounds in the marine environment are not well known. In this study, the occurrence and removal efficiencies of 12 organic UV filters in five wastewater treatment plants (WWTPs) equipped with different treatment levels in Hong Kong, South China, were investigated during one year and a preliminary environmental risk assessment was carried out. Using a newly developed simultaneous multiclass quantification liquid chromatography-tandem mass spectrometry (LC-MS/MS) method, butyl methoxydibenzoylmethane (BMDM), 2,4-dihydroxybenzophenone (BP-1), benzophenone-3 (BP-3), benzophenone-4 (BP-4) and 2-ethyl-hexyl-4-trimethoxycinnamate (EHMC) were frequently (≥80%) detected in both influent and effluent with mean concentrations ranging from 23 to 1290 ng/L and 18-1018 ng/L, respectively; less than 2% of samples contained levels greater than 1000 ng/L. Higher concentrations of these frequently detected compounds were found during the wet/summer season, except for BP-4, which was the most abundant compound detected in all samples in terms of total mass. The target compounds behaved differently depending on the treatment level in WWTPs; overall, removal efficiencies were greater after secondary treatment when compared to primary treatment with >55% and <20% of compounds showing high removal (defined as >70% removal), respectively. Reverse osmosis was found to effectively eliminate UV filters from effluent (>99% removal). A preliminary risk assessment indicated that BP-3 and EHMC discharged from WWTPs may pose high risk to fishes in the local environment.


Assuntos
Estações do Ano , Protetores Solares/análise , Eliminação de Resíduos Líquidos/instrumentação , Águas Residuárias/análise , Poluentes Químicos da Água/análise , Animais , Cromatografia Líquida , Monitoramento Ambiental , Peixes/metabolismo , Medição de Risco , Espectrometria de Massas por Ionização por Electrospray , Espectrometria de Massas em Tandem
13.
Community Ment Health J ; 49(6): 841-6, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23756723

RESUMO

Family members charged with the care of those suffering from schizophrenia experience considerable stress due to their multiple responsibilities. Research regarding the burdens of caregiving is scant in Hong Kong and China. The present study quantified the association of the duties of caregivers with mental health symptoms in two Asian cities having distinct health care systems (i.e., Hong Kong and Guangzhou, China). Thirty nine caregivers in Hong Kong and 70 caregivers in Guangzhou were recruited from nongovernmental mental health organizations. They were assessed using the Chinese version of the Involvement Evaluation Questionnaire and the General Health Questionnaire. While the Guangzhou family caregivers had a significantly higher burden than the Hong Kong sample, there was no significant difference in the psychological health status of family caregivers in the two cities. Result of correlational analyses, however, revealed high associations between burden of care variables and the psychological health of the caregivers. Findings for the present study have implications regarding the physical and mental health needs of those caring for seriously disturbed relatives.


Assuntos
Cuidadores/psicologia , Efeitos Psicossociais da Doença , Esquizofrenia/terapia , Cuidadores/estatística & dados numéricos , China/epidemiologia , Feminino , Nível de Saúde , Hong Kong/epidemiologia , Humanos , Masculino , Saúde Mental/estatística & dados numéricos , Inquéritos e Questionários
14.
Environ Health Perspect ; 121(7): 839-46, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23665928

RESUMO

BACKGROUND: Pharmaceuticals are known to contaminate tap water worldwide, but the relevant human health risks have not been assessed in China. OBJECTIVES: We monitored 32 pharmaceuticals in Chinese tap water and evaluated the life-long human health risks of exposure in order to provide information for future prioritization and risk management. METHODS: We analyzed samples (n = 113) from 13 cities and compared detected concentrations with existing or newly-derived safety levels for assessing risk quotients (RQs) at different life stages, excluding the prenatal stage. RESULTS: We detected 17 pharmaceuticals in 89% of samples, with most detectable concentrations (92%) at < 50 ng/L. Caffeine (median-maximum, nanograms per liter: 24.4-564), metronidazole (1.8-19.3), salicylic acid (16.6-41.2), clofibric acid (1.2-3.3), carbamazepine (1.3-6.7), and dimetridazole (6.9-14.7) were found in ≥ 20% of samples. Cities within the Yangtze River region and Guangzhou were regarded as contamination hot spots because of elevated levels and frequent positive detections. Of the 17 pharmaceuticals detected, 13 showed very low risk levels, but 4 (i.e., dimetridazole, thiamphenicol, sulfamethazine, and clarithromycin) were found to have at least one life-stage RQ ≥ 0.01, especially for the infant and child life stages, and should be considered of high priority for management. We propose an indicator-based monitoring framework for providing information for source identification, water treatment effectiveness, and water safety management in China. CONCLUSION: Chinese tap water is an additional route of human exposure to pharmaceuticals, particularly for dimetridazole, although the risk to human health is low based on current toxicity data. Pharmaceutical detection and application of the proposed monitoring framework can be used for water source protection and risk management in China and elsewhere.


Assuntos
Água Potável/análise , Exposição Ambiental , Monitoramento Ambiental/métodos , Preparações Farmacêuticas/análise , Poluentes Químicos da Água/análise , Purificação da Água , Adolescente , Adulto , Biomarcadores/análise , Criança , Pré-Escolar , China , Cromatografia Líquida de Alta Pressão , Cidades , Feminino , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Medição de Risco , Espectrometria de Massas em Tandem , Adulto Jovem
15.
Environ Pollut ; 176: 10-7, 2013 May.
Artigo em Inglês | MEDLINE | ID: mdl-23410673

RESUMO

Wastewater treatment plants (WWTPs) are a significant source for poly-/perfluoroalkyl substances (PFASs) entering the environment. The presence of PFASs in twenty-eight municipal WWTPs from eleven cites in economically developed areas of China were screened. Overall, perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) were dominant in wastewater and sludge, and were not effectively removed during wastewater treatment. Elevated influent concentration ratios of perfluorobutanoic acid (PFBA) to PFOA and perfluorobutane sulfonate (PFBS) to PFOS in some WWTPs suggested that short chains substitution were adopted in these cities. Cluster analysis showed treatment processes had important impacts on PFASs profiles in effluent and sludge. Average concentration of total PFCAs in influent from each city and its gross domestic product (GDP) had significant positive correlation. This study provides a snapshot of both domestic and industrial discharges of PFAS to WWTPs as well as PFAS discharge from WWTPs to the aquatic environment in China.


Assuntos
Monitoramento Ambiental , Fluorocarbonos/análise , Eliminação de Resíduos Líquidos , Águas Residuárias/química , Poluentes Químicos da Água/análise , China , Cidades , Poluição Química da Água/estatística & dados numéricos
16.
Chemosphere ; 89(8): 944-9, 2012 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-22863061

RESUMO

Muscle tissues of large yellow croakers (Pseudosciaena crocea) and sliver pomfret (Pampus argenteus) from nine coastal cities of East China including Dalian, Tianjin, Qingdao, Shanghai, Zhoushan, Wenzhou, Fuzhou, Quanzhou and Xiamen were analyzed for polychlorinated biphenyl (PCB) concentrations. Thirty-six PCB congeners were quantified in the fishes, of which 11 congeners were dioxin-like PCBs. The total PCB concentrations of the present study were at the low end of the global range, which may be related to the smaller usage and shorter consumption history of PCBs in China. PCBs 18, 29, 52, 66, 101, 104, 138, 153, 180 and 194 were the major constituents found in the fish samples. Regression analysis showed a strong positive correlation (R(2)=0.800; p<0.001) between total dioxin-like PCBs and total PCB concentrations, and that total PCB concentrations explain 80% of the variability in total dioxin-like PCB concentrations. Among the species investigated, significantly higher concentrations of total PCBs were found in croakers than in pomfrets, which may be attributed to their different feeding and living habits. No significant difference in total PCB concentrations among the cities was observed; principal component analysis (PCA) of PCB profiles indicated that PCB pollution came from similar sources in the sampling areas and that there may be other PCB sources in Dalian and Wenzhou. The calculated carcinogenic risks (CRs) from the two species based on a low consumption group and high consumption group were all greater than 10(-6), suggesting that daily exposure to dioxin-like PCBs via fish consumption results in a lifetime cancer risk of greater than one in one million. In contrast, the hazard quotients (HQs) of noncancer risks were all less than unity.


Assuntos
Perciformes , Bifenilos Policlorados/análise , Medição de Risco , Animais , China , Exposição Ambiental , Contaminação de Alimentos/análise , Humanos , Músculos/química , Análise de Componente Principal
17.
Environ Int ; 42: 1-9, 2012 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-21450345

RESUMO

Occurrence, removal, consumption and environmental risks of sixteen antibiotics were investigated in several sewage treatment plants (STPs) featuring different treatment levels in Hong Kong, China. Cefalexin, ofloxacin and erythromycin-H(2)O were predominant with concentrations of 1020-5640, 142-7900 and 243-4740 ng/L in influent, respectively; their mass loads were comparable to levels reported in urban regions in China and were at the high end of the range reported for western countries. The target antibiotics behaved differently depending on the treatment level employed at the STPs and relatively higher removal efficiencies (>70%) were observed for cefalexin, cefotaxime, amoxicillin, sulfamethoxazole and chloramphenicol during secondary treatment. ß-lactams were especially susceptible to removal via the activated sludge process while macrolides were recalcitrant (<20%) in the dissolved phase. Two fluoroquinolones, ofloxacin (4%) and norfloxacin (52%), differed greatly in their removal efficiencies, probably because of disparities in their pK(a) values which resulted in different sorption behaviour in sludge. Overall antibiotic consumption in Hong Kong was back-calculated based on influent mass flows and compared with available prescription and usage data. This model was verified by a good approximation of 82% and 141% to the predicted consumption of total ofloxacin, but a less accurate estimate was obtained for erythromycin usage. Risk assessment indicated that algae are susceptible to the environmental concentrations of amoxicillin as well as the mixture of the nine detected antibiotics in receiving surface waters.


Assuntos
Antibacterianos/análise , Eliminação de Resíduos Líquidos/estatística & dados numéricos , Poluentes Químicos da Água/análise , Poluição Química da Água/estatística & dados numéricos , Amoxicilina/análise , Cefalexina/análise , China , Cloranfenicol/análise , Uso de Medicamentos/estatística & dados numéricos , Monitoramento Ambiental , Eritromicina/análise , Fluoroquinolonas/análise , Hong Kong , Humanos , Macrolídeos/análise , Ofloxacino/análise , Medição de Risco , Esgotos/química , beta-Lactamas/análise
18.
Nurse Educ Today ; 32(3): 214-8, 2012 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-21481993

RESUMO

A group project is a common method of assessment in higher education worldwide. The use of an adjunct peer assessment (PA) scheme as a means to award marks for individual student contributions to a group project has increased. However, nursing students' perceptions of PA have not been well studied. This paper examines baccalaureate nursing students' perceptions of PA in assessing individual contributions to a group project. Using a case study design with both quantitative (an anonymous survey with 123 students), and qualitative methods (six focus group interviews with 21 students), data were collected from students in a baccalaureate nursing programme. Merging of quantitative and qualitative findings indicated that students overall had positive perceptions of PA, especially its ability to reduce 'free-riding'. However, students also had some interpersonal and operational concerns about the PA implementation process. Based on the findings, we recommend: (1) further developing students' abilities to assess the contributions of others to the task and relationship functions in group work; and (2) adopting a confidential online system for submission of PA forms.


Assuntos
Atitude do Pessoal de Saúde , Bacharelado em Enfermagem/métodos , Grupo Associado , Percepção , Estudantes de Enfermagem/psicologia , Feminino , Grupos Focais , Humanos , Relações Interprofissionais , Masculino , Pesquisa em Educação em Enfermagem , Pesquisa Metodológica em Enfermagem , Pesquisa Qualitativa , Adulto Jovem
19.
Arthritis Care Res (Hoboken) ; 63(11): 1576-83, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-22034119

RESUMO

OBJECTIVE: To determine the effect of tai chi exercise on persistent low back pain. METHODS: We performed a randomized controlled trial in a general community setting in Sydney, New South Wales, Australia. Participants consisted of 160 volunteers between ages 18 and 70 years with persistent nonspecific low back pain. The tai chi group (n = 80) consisted of 18 40-minute sessions over a 10-week period delivered in a group format by a qualified instructor. The waitlist control group continued with their usual health care. Bothersomeness of back symptoms was the primary outcome. Secondary outcomes included pain intensity and pain-related disability. Data were collected at pre- and postintervention and analyzed by intent-to-treat. RESULTS: Tai chi exercise reduced bothersomeness of back symptoms by 1.7 points on a 0-10 scale, reduced pain intensity by 1.3 points on a 0-10 scale, and improved self-report disability by 2.6 points on the 0-24 Roland-Morris Disability Questionnaire scale. The followup rate was >90% for all outcomes. These results were considered a worthwhile treatment effect by researchers and participants. CONCLUSION: This is the first pragmatic randomized controlled trial of tai chi exercise for people with low back pain. It showed that a 10-week tai chi program improved pain and disability outcomes and can be considered a safe and effective intervention for those experiencing long-term low back pain symptoms.


Assuntos
Dor Lombar/terapia , Tai Chi Chuan , Adulto , Efeitos Psicossociais da Doença , Avaliação da Deficiência , Feminino , Humanos , Modelos Lineares , Dor Lombar/diagnóstico , Dor Lombar/fisiopatologia , Masculino , Pessoa de Meia-Idade , New South Wales , Medição da Dor , Estudos Prospectivos , Recuperação de Função Fisiológica , Índice de Gravidade de Doença , Fatores de Tempo , Resultado do Tratamento
20.
J Air Waste Manag Assoc ; 61(8): 850-7, 2011 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-21874956

RESUMO

Thirty-three soil samples were collected from the Luling, Liuer, and Zhangji coal mines in the Huaibei and Huainan areas of Anhui Province, China. The samples were analyzed for antimony (Sb) by inductively coupled plasma-optical emission spectrometry (ICP-OES) method. The average Sb content in the 33 samples was 4 mg kg(-1), which is lower than in coals from this region (6.2 mg kg(-1)). More than 75% of the soils sampled showed a significant degree of Sb pollution (enrichment factors [EFs] 5-20). The soils collected near the gob pile and coal preparation plant were higher in Sb content than those collected from residential areas near the mines. The gob pile and tailings from the preparation plant were high in mineral matter content and high in Sb. They are the sources of Sb pollution in surface soils in the vicinity of coal mines. The spatial dispersion of Sb in surface soil in the mine region shows that Sb pollution could reach out as far as 350 m into the local environment conditions. Crops in rice paddies may adsorb some Sb and reduce the Sb content in soils from paddyfields. Vertical distribution of Sb in two soil profiles indicates that Sb is normally relatively immobile in soils.


Assuntos
Antimônio/análise , Minas de Carvão , Poluentes do Solo/análise , China , Monitoramento Ambiental/métodos , Solo/análise
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