RESUMO
Croatian Consensus Conferences on Viral Hepatitis took place in 2005 and 2009. Considering the numerous novel concepts on the epidemiology, diagnosis and management of viral hepatitis (chronic hepatitis C genotype 1 in particular) that have emerged in the past four years, a new Croatian Consensus Conference on Viral Hepatitis was held in Zagreb on February 28, 2013. The abridged text of the Croatian Consensus Conference on Viral Hepatitis 2013 presents the new concepts on the epidemiology of viral hepatitis, serologic and molecular diagnosis of viral hepatitis, determination of the IL-28 gene promoter polymorphism, fibrosis grading, algorithm for patient diagnostic follow up, treatment of chronic hepatitis C (genotypes 1-6) and hepatitis B, treatment of special populations (children, dialysis patients, transplanted patients, individuals with HIV/HCV co-infection), and therapy side effects.
Assuntos
Hepacivirus/isolamento & purificação , Hepatite Viral Humana/diagnóstico , Hepatite Viral Humana/tratamento farmacológico , Adolescente , Adulto , Fatores Etários , Idoso , Criança , Croácia/epidemiologia , Atenção à Saúde/organização & administração , Genótipo , Hepacivirus/genética , Hepatite B Crônica/diagnóstico , Hepatite B Crônica/tratamento farmacológico , Hepatite C Crônica/diagnóstico , Hepatite C Crônica/tratamento farmacológico , Hepatite Viral Humana/epidemiologia , Hepatite Viral Humana/genética , Humanos , Pessoa de Meia-Idade , Fatores de Risco , Adulto JovemAssuntos
DNA Bacteriano/sangue , DNA Fúngico/sangue , Reação em Cadeia da Polimerase/métodos , Sepse/diagnóstico , Anti-Infecciosos/uso terapêutico , Técnicas Bacteriológicas , Humanos , Reação em Cadeia da Polimerase/economia , Reação em Cadeia da Polimerase/instrumentação , Sepse/tratamento farmacológicoRESUMO
There are limited data on how HIV prevention interventions affect individuals presenting to care in settings with a low-level HIV epidemic. We examined whether interventions undertaken during the Croatian Global Fund Project in 2004-2006 had an influence on patients entering care. The number of men who have sex with men (MSM) presenting in 2004-2006 (n = 86) was 59% higher than in 2001-2003 (n = 54); in heterosexual patients the increase was 14% (n = 51 in 2001-2003; n = 58 in 2004-2006). MSM presented at a younger age (median 32 years) in 2004-2006 than in 2001-2003 (median 36 years). Late presentation to care was found in 28% of MSM and in 59% of heterosexual patients in 2004-2006. MSM were less frequently late presenters in 2004-2006 compared with 2001-2003 (odds ratio, 0.48; 95% confidence interval, 0.24 to 0.99; P = 0.046). Additional strategies for earlier initiation of care must be developed for MSM and particularly for heterosexual patients.