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Despite increasing global attention towards sustainable development, the empirical linkage between green financing and the enhancement of environmental and social governance (ESG) practices within industries remains underexplored. This study investigates the influence of green financing on Corporate Social Responsibility (CSR) and environmental policies and procedures in 40 Chinese industries from 2010 to 2020. By employing a baseline regression and a difference-in-differences methodology, this paper aims to quantify the extent to which green financing initiatives have impacted CSR activities and the adoption of rigorous environmental policies and procedures in the Chinese industrial sector. The results indicate that industries with access to green financing have shown significant improvements in their CSR engagements and the stringency of their environmental policies and procedures compared to those without such financial incentives. Specifically, the difference-in-differences analysis reveals a positive and statistically significant effect of green financing on the adoption of more stringent environmental policies and the enhancement of CSR practices. We identify the specific areas within CSR and environmental policies that are most influenced by green financing. We assess the effectiveness of green financing as a tool for promoting sustainable industrial practices. The analysis utilizes a comprehensive dataset, including industry-specific financing and ESG performance indicators, to conduct a longitudinal assessment over the decade in question. Based on these findings, the study concludes with a policy implication that emphasizes the critical role of green financing as a catalyst for improving CSR and environmental standards in industries. It suggests that policymakers and financial institutions should consider expanding green financing mechanisms to accelerate the transition towards more sustainable industrial practices.
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The current energy crisis is worsening worldwide, and in China, urban expansion and per capita vehicle ownership have created a growing energy imbalance and increased pressure to reduce carbon emissions.The popularization of new energy vehicles (NEVs) can provide a step forward to solving energy shortage problems, environmental pollution, and global warming. In 2022, the average penetration rate, which is ratio of new energy vehicle sales to vehicle sales, is just 19.1 %. This paper analysed the reasons for the differences in the penetration rates of new energy vehicles in China's 269 prefecture-level cities, using a Geo Detector approach, and the results showed that the level of economic development, the average annual temperature difference, the density of charging piles, the charging price and the number of population all had significant effects(qï¼0.12) on the penetration rate. Based on the above studies, a questionnaire was used to investigate the public's acceptance of new energy vehicles in Xinjiang Uygur Autonomous Region, and a PLS-SEM regression analysis was conducted. The results showed that men, young people and people with a certain level of basic education were 5 % more likely to accept new energy vehicles.Unlike previous studies, perceived cost had no significant correlation with the acceptance of new energy vehicles. Perceived risk had a significant negative correlation with the acceptance of new energy vehicles,the path coefficient is -0.1.The acceptance of new energy vehicles was significantly and positively correlated with vehicle quality and service, the public's understanding of new energy vehicles, and subjective norms, their average path coefficients are above 0.1. We argues that the government should maintain a certain level of promotion of new energy vehicles and accelerate the construction of charging piles, based on the aforementioned results.
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The One Health (OH) approach is used to control/prevent zoonotic events. However, there is a lack of tools for systematically assessing OH practices. Here, we applied the Global OH Index (GOHI) to evaluate the global OH performance for zoonoses (GOHI-Zoonoses). The fuzzy analytic hierarchy process algorithm and fuzzy comparison matrix were used to calculate the weights and scores of five key indicators, 16 subindicators, and 31 datasets for 160 countries and territories worldwide. The distribution of GOHI-Zoonoses scores varies significantly across countries and regions, reflecting the strengths and weaknesses in controlling or responding to zoonotic threats. Correlation analyses revealed that the GOHI-Zoonoses score was associated with economic, sociodemographic, environmental, climatic, and zoological factors. Additionally, the Human Development Index had a positive effect on the score. This study provides an evidence-based reference and guidance for global, regional, and country-level efforts to optimize the health of people, animals, and the environment.
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Rapid population aging has been placing heavy tolls on Chinese family caregivers. Previous empirical evidence from multiple countries have shown that establishing national long-term care insurance was effective in reducing family care burdens. Utilizing data from the China Health and Retirement Longitudinal Study (CHARLS) wave 2011 to 2018, this study examined the effects of implementing the pilot long-term care insurance program on family care received by the Chinese older adults, by using a time-varying Difference-in-Differences (DID) method. The results showed that: (1) the implementation of the pilot long-term care insurance program has led to a 17.2% decline in general for family care received by the Chinese older adults. (2) The effect of participating in the pilot program on family care received differed by respondent's household registration, health status, marital status, and possesion of retirement pension, and were specifically pronounced among those who were urban residents, having spouse, living with disabilities, and living with no retirement pension. (3) Further results from the mechanism analyses showed that the pilot long-term care insurance program decreased the level of family care by reducing the dual intergenerational financial support between older adults and their adult children. (4) Although participating in the pilot program decreased older adult's dependence on their adult children, their physical and mental health status were not negatively affected. This study contributes to the existing literature by evaluating the effects of implementing the pilot long-term care insurance program on family care received by the Chinese older adults, and lends supports to the previous studies that participating in long-term care insurance significantly reduces old adults' demand for family care, but not in sacrifice of their physical and mental well-being.
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Cuidadores , Seguro de Assistência de Longo Prazo , Humanos , Idoso , Seguro de Assistência de Longo Prazo/economia , Masculino , Feminino , Cuidadores/economia , Cuidadores/psicologia , Pessoa de Meia-Idade , Estudos Longitudinais , China , Idoso de 80 Anos ou mais , Projetos Piloto , Aposentadoria/economia , Relação entre Gerações , Filhos Adultos/psicologia , Assistência de Longa Duração/economia , FamíliaRESUMO
BACKGROUND: Transport accidents are one of the leading causes of child morbidity and mortality worldwide and represent a significant public health burden. This study aimed to investigate the hospitalization information and burden of pediatric inpatients in transport accidents in China. METHODS: In this study, we collected the cover page of the medical records of pediatric inpatients in transport accidents using the Futang Research Center of Pediatric Development (FRCPD) database from January 1, 2016 to December 31, 2021. Then, we extracted the epidemiological characteristics, including demographic characteristics, cases distribution, disease information, and hospitalization burden. RESULTS: Among 36,455 included inpatients, males, aged 1-3 years, East China, July were dominant in different subgroups. In transport accidents, pedestrians were the most frequently type of injury (65.69%). Of all known lesions, craniocerebral/nerve injury was the more common results in pediatric inpatients in transport accidents (33.93%). In addition to pedal cyclists more susceptible to sport system injury, other types of injured person with transport accidents were mainly craniocerebral/nerve injury. In terms of the type of discharge, occupant of heavy transport vehicle or bus and people with craniocerebral/nerve injury had the highest mortality rate after hospitalization in all type and lesion of injured person groups, respectively. The largest hospitalization burden in the type of injured person was occupant of heavy transport vehicle or bus. CONCLUSIONS: This study revealed that epidemiological characteristics and the main factor influencing the hospitalization information and burden of children with traffic accidents in China.
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Acidentes de Trânsito , Hospitalização , Humanos , Masculino , Feminino , Pré-Escolar , China/epidemiologia , Lactente , Hospitalização/estatística & dados numéricos , Acidentes de Trânsito/estatística & dados numéricos , Criança , Adolescente , Pacientes Internados/estatística & dados numéricos , Ferimentos e Lesões/epidemiologia , Efeitos Psicossociais da Doença , Recém-NascidoRESUMO
Lactoferrin (LTF) has diverse biological activities and is widely used in functional foods and active additives. Nevertheless, evaluating the proteoform heterogeneity, conformational stability, and activity of LTF remains challenging during its production and storage processes. In this study, we describe the implementation of native mass spectrometry (nMS), glycoproteomics, and an antimicrobial activity assay to assess the quality of LTF. We systematically characterize the purity, glycosylation heterogeneity, conformation, and thermal stability of LTF samples from different sources and transient high-temperature treatments by using nMS and glycoproteomics. Meanwhile, the nMS peak intensity and antimicrobial activity of LTF samples after heat treatment decreased significantly, and the two values were positively correlated. The nMS results provide essential molecular insights into the conformational stability and glycosylation heterogeneity of different LTF samples. Our results underscore the great potential of nMS for LTF quality control and activity evaluation in industrial production.
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Lactoferrina , Espectrometria de Massas , Lactoferrina/química , Lactoferrina/metabolismo , Glicosilação , Estabilidade Proteica , Animais , Conformação Proteica , Bovinos , Temperatura AltaRESUMO
High transportation costs have been a barrier to the expansion of agriculture in the interior of Brazil. To reduce transportation costs, Brazil launched the National Logistics Plan, aiming to expand its railway network by up to 91 % by 2035. Such a large-scale infrastructure investment raises concerns about its economic and environmental consequences. By combining geospatial estimation of transportation cost with a grid-resolving, multi-scale economic model that bridges fine-scale crop production with its trade and demand from national and global perspectives, we explore impacts of transportation infrastructure expansion on agricultural production, land use changes, and carbon emissions both locally and nationally in Brazil. We find that globally, the impacts on output and land use changes are small. However, within Brazil, the plan's primary impacts are impressive. PNL2035 results in the reduction of transportation costs by 8-23 % across states (depending on expansion's extent) in the interior Cerrado biome. This results in cropland expansion and increases in terrestrial carbon emissions in the Cerrado region. However, the increase in terrestrial carbon emissions in the Cerrado is offset by spillover effects elsewhere in Brazil, as crop production shifts away from the Southeast-South regions and accompanying change in the mix of transportation mode for farm products from roadway to more emission-efficient railway. Furthermore, we argue that the transportation infrastructure's impact on the enhanced mobility of labor and other agricultural inputs would further accentuate the regional shift in agricultural production and contribute to carbon emission mitigation. Upon its completion, PNL2035 is expected to result in the reduction of net national emissions by 1.8-30.7 million metric ton of CO2-equivalent, depending on the impacts on labor and purchased input mobility. We conclude that the omission of spillover effects due to infrastructure expansion can lead to misleading assessments of transport policies.
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The safety of drinking water is a significant environmental issue of great concern for human health since numerous contaminants are often detected in drinking water and its sources. Boiling is a common household method used to produce relatively high-quality drinking water in some countries and regions. In this study, with the aid of an integrated approach of in vitro bioassays and non-target analysis based on high-resolution mass spectrometry coupled with liquid chromatography, alterations in endocrine-disrupting activities in tap water samples without and with boiling were revealed, as well as the potential endocrine-disrupting chemicals (EDCs) contributing to these alterations were identified. The organic extracts of tap water had no significant (ant)agonistic activities against an estrogen receptor (ER), progesterone receptor (PR), glucocorticoid receptor (GR), and mineralocorticoid receptor (MR) at enrichment concentrations of ≤10 times, posing no immediate or acute health risk to humans. However, the presence of agonistic activities against PR and MR and antagonistic activities against ER, PR, GR, and MR in OEs of tap water at relatively higher enrichment concentrations still raise potential health concerns. Boiling effectively reduced antagonistic activities against these steroid hormone receptors (SHRs) but increased estrogenic and glucocorticoid activities in drinking water. Four novel potential EDCs, including one UV filter (phenylbenzimidazole sulfonic acid, PBSA) and three natural metabolites of organisms (beta-hydroxymyristic acid, 12-hydroxyoctadecanoic acid, and isorosmanol) were identified in drinking water samples, each of which showed (ant)agonistic activities against different SHRs. Given the widespread use of UV filters in sunscreens to prevent skin cancer, the health risks posed by PBSA as an identified novel EDC are of concern. Although boiling has been thought to reduce the health risk of drinking water contamination, our findings suggest that boiling may have a more complex effect on the endocrine-disrupting activities of drinking water and, therefore, a more comprehensive assessment is needed.
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BACKGROUND: Assisted reproductive technologies (ARTs) have become the main treatment for infertility. ART treatment can be a stressful life event for infertile females. Whether there is an association between ARTs and postpartum depressive symptoms (PDS) has not been established. METHODS: PubMed, MEDLINE, EMBASE, PsycINFO, and CNKI were searched. The pooled outcome was the difference in incidence of PDS within 1 year postpartum between ARTs and the spontaneous pregnancy group. RESULTS: A total of 12 cohort studies, which were conducted in eight developed countries and two developing countries, were involved. In total, 106,338 pregnant women, including 4990 infertile females with ARTs treatment and 101,348 women with spontaneous pregnancy, were enrolled in our final analysis. ARTs women had a lower incidence of PDS compared to the spontaneous pregnancy group according to a random effect model (OR = 0.83, 95 % CI: 0.71-0.97, p = 0.022, I2 = 62.0 %). Subgroup analyses indicated that studies on late PDS (follow-up: 3-12 months postpartum) were more heterogeneous than those on early PDS (follow-up: <3 months postpartum) (I2 = 24.3 % vs. I2 = 0 %, interaction p-value < 0.001). There was a strong relationship between ARTs and late PDS (OR = 0.65, 95 % CI: 0.55-0.77, p < 0.001). Therefore, the possible source of heterogeneity was the postpartum evaluation time, which was confirmed by post-hoc meta-regression. LIMITATIONS: Some underlying confounders, such as previous psychiatric illness, the limited availability of ARTs, and ethnic disparities, cannot be ignored and may have biased interpretation of the results. CONCLUSION: The available data suggested that ARTs were associated with lower incidence of PDS, especially when follow-up lasted over 3 months. However, these findings should be interpreted with caution. Better-designed trials are needed to confirm this association.
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Depressão Pós-Parto , Técnicas de Reprodução Assistida , Humanos , Feminino , Depressão Pós-Parto/epidemiologia , Depressão Pós-Parto/terapia , Técnicas de Reprodução Assistida/estatística & dados numéricos , Gravidez , Adulto , Infertilidade Feminina/psicologia , Infertilidade Feminina/terapia , IncidênciaRESUMO
In the multifaceted realm of environmental governance, emphasizing public environmental participation as an informal regulatory mechanism, alongside the influence of formal governmental environmental regulation on regional carbon emissions, contributes to providing empirical evidence and policy insights for China's "dualcarbon target" action plan. Using data from 282 prefecture-level cities in China from 2011 to 2020, this research develops an analytical framework for urban carbon emissions encompassing public environmental concern, environmental regulation, green finance, and industrial agglomeration. And through an amalgamation of theoretical insights and empirical validation, the study elucidates the mechanisms by which public environmental concern impact urban carbon emissions. It further delves into the mediating role of environmental regulation and the moderating effects of green finance and industrial agglomeration. It reveals that: (1) Public environmental concern significantly reduces urban carbon emissions, particularly in northern cities, non-environmental protection key cities, and resource regeneration cities. And this suppressive influence is markedly more potent via mobile platforms compared to PC channels; (2) Environmental regulation serves as a partially mediating role between public environmental concern and urban carbon emissions, suggesting that public environmental concern reduces emissions by amplifying governmental environmental oversight; (3) Both green finance and industrial agglomeration play a positive moderating role on the effect of public environmental concern in reducing urban carbon emissions.
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A recent study published data on the growth performance, relative weights of the organs of the gastrointestinal tract, liver histology, serum biochemistry, and hematological parameters for turkey poults fed an experimental diet contaminated with aflatoxin B1 (AFB1) and humic acids (HA) extracted from vermicompost. The negative effects of AFB1 (250 ng AFB1/g of feed) were significantly reduced by HA supplementation (0.25% w/w), suggesting that HA might be utilized to ameliorate the negative impact of AFB1 from contaminated diets. The present study shows the results of the remaining variables, as an extension of a previously published work which aimed to evaluate the impact of HA on the intestinal microbiota, gut integrity, ileum morphometry, and cellular immunity of turkey poults fed an AFB1-contaminated diet. For this objective, five equal groups of 1-day-old female Nicholas-700 turkey poults were randomly assigned to the following treatments: negative control (basal diet), positive control (basal diet + 250 ng AFB1/g), HA (basal diet + 0.25% HA), HA + AFB1 (basal diet + 0.25% HA + 250 ng AFB1/g), and Zeolite (basal diet + 0.25% zeolite + 250 ng AFB1/g). In the experiment, seven replicates of ten poults each were used per treatment (n = 70). In general, HA supplementation with or without the presence of AFB1 showed a significant increase (p < 0.05) in the number of beneficial butyric acid producers, ileum villi height, and ileum total area, and a significant reduction in serum levels of fluorescein isothiocyanate-dextran (FITC-d), a marker of intestinal integrity. In contrast, poults fed with AFB1 showed a significant increase in Proteobacteria and lower numbers of beneficial bacteria, clearly suggesting gut dysbacteriosis. Moreover, poults supplemented with AFB1 displayed the lowest morphometric parameters and the highest intestinal permeability. Furthermore, poults in the negative and positive control treatments had the lowest cutaneous basophil hypersensitivity response. These findings suggest that HA supplementation enhanced intestinal integrity (shape and permeability), cellular immune response, and healthier gut microbiota composition, even in the presence of dietary exposure to AFB1. These results complement those of the previously published study, suggesting that HA may be a viable dietary intervention to improve gut health and immunity in turkey poults during aflatoxicosis.
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Microbioma Gastrointestinal , Zeolitas , Animais , Feminino , Aflatoxina B1 , Ácido Butírico , Dieta , Substâncias Húmicas , Imunidade Celular , PerusRESUMO
Bioconversion of lignocellulosic biomass is a highly promising alternative to rapidly reduce reliance on fossil fuels and greenhouse gas emissions. However, the use of lignocellulosic biomass is limited by the challenges of efficient degradation strategies. Given this need, Bacillus tropicus (B. tropicus) with cellulose degradation ability was isolated and screened from rotten dahlia. The strain efficiently utilized coconut oil cake (COC) to secrete 167.3 U/mL of cellulase activity. Electron microscopy results showed significant changes in the structure and properties of cellulose after treatment with B. tropicus, which increased the surface accessibility and the efficiency of the hydrolysis process. The functional group modification observed by Fourier transform infrared spectroscopy indicated the successful depolymerization of COC. The X-ray diffraction pattern showed that the crystallinity index increased from 44.8% to 48.2% due to the hydrolysis of the amorphous region in COC. The results of colorimetry also reveal an efficient hydrolysis process. A co-culture of B. tropicus and Saccharomyces cerevisiae was used to produce ethanol from COC waste, and the maximum ethanol yield was 4.2 g/L. The results of this work show that B. tropicus can be used to prepare biotechnology value-added products such as biofuels from lignocellulosic biomass, suggesting promising utility in biotechnology applications.
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Background: Traditional observational studies have found a possible risk association of the gut microbiota for psoriasis. Meanwhile, psoriasis may also affect the changes in the gut microbiota. However, the available evidence does not demonstrate a reciprocal relationship between the gut microbiota and psoriasis. This limits our understanding on the role of the gut microbiota in the mechanisms of psoriasis. Methods: To address this question we used Mendelian randomization, a novel epidemiological approach, and acquired the largest current gut microbiota GWAS data from the MiBioGen consortium as well as psoriasis GWAS data from the FinnGen consortium, and performed two-sample bidirectional MR analyses using a multiple MR analysis approach. Finally, the robustness of the results was assessed by sensitivity analysis. Results: Our results indicate that five bacterial genera are causally related to psoriasis and psoriasis is causally related to four bacterial genera. Conclusion: These results suggest a bidirectional causal influence of psoriasis on the gut microbiota. Our results somewhat challenge the causal inferences of previous observational studies. We found that the specific bacterial genera with a risk effect on psoriasis were different from those found to characterize psoriasis in previous observational studies, and that these psoriasis-characterizing genera were inversely associated with psoriasis.
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PURPOSE: Omadacycline (PTK-0796) is a first-in-class aminomethylcycline for adult patients with community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible pathogens. We investigated the pharmacokinetic (PK) and pharmacodynamic (PD) profile of omadacycline, considering the impact of covariates, particularly ethnicity, on PK and determined the PK/PD cutoff values for dosing regimens. METHODS: Utilizing nonlinear mixed-effects modeling, we pooled data from 11 clinical trials for PopPK analysis. The first-order conditional estimation with interaction (FOCEI) method in NONMEM facilitated model parameter estimation. Employing a stepwise model selection strategy, with forward addition (P < 0.01) and backward deletion (P < 0.001), we assessed the potential impacts of covariates on omadacycline PK, including baseline age, body weight, sex, race, body mass index, body surface area, baseline albumin, creatine clearance, and formulation. After validating the model through various methods, the final PopPK model underwent Monte Carlo simulations to generate the PK profile for the Chinese population. This enabled AUC calculation and assessment of the probability of target attainment (PTA) and the cumulative fraction of response (CFR) for various dosing regimens and bacterial strains. RESULTS: Omadacycline's PK can be adequately characterized by a three-compartment model. Body weight, sex, race, and drug formulation statistically influenced its PK. Asians and non-Asians exhibit similar exposure after intravenous infusion, but oral dosing results in much higher exposures than in non-Asians. Monte Carlo simulation indicates that IV-only or IV/PO sequential therapy regimens provide adequate attainment for all major pathogens causing ABSSSI and CABP. PK/PD cutoffs were generally above the MIC90 value of recent clinical isolates from China. CONCLUSIONS: In conclusion, the approved regimen for China achieved adequate target attainment for all pathogens typically associated with these infections. The higher oral exposure observed in Asians may enhance efficacy without affecting safety or tolerability.
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Antibacterianos , Tetraciclinas , Adulto , Humanos , Antibacterianos/farmacologia , Tetraciclinas/farmacologia , Bactérias , Peso Corporal , Testes de Sensibilidade Microbiana , Método de Monte CarloRESUMO
This study develops a novel Taguchi-STIRPAT input-output (TSIO) model for exploring pathways to reduce carbon emission from the perspective of household consumption, through incorporating input-output model (IOM), Taguchi design (TD), and STIRPAT model. TSIO can not only identify the main factors (carbon emission intensity, consumption structure, per capita consumption, and population) and evaluate their effects on indirect household carbon emissions (IHC), but also predict IHC from a long-term perspective to achieve the dual-carbon target. TSIO is then applied to Fujian province (China), where multiple scenarios related to multiple factors with multiple levels are examined. Results reveal that (i) among all sectors, the highest contributors to IHC are residence (RES), followed by food, cigarettes, and drinks (FCD), and transport and communication (TC); it is suggested that the government can consider market mechanism to control these high-carbon emission consumption behaviors; (ii) the decline in the share of RES consumption has the largest effect on rural and urban IHC; the share of RES consumption is considered to be a key factor in predicting carbon emissions; (iii) under the optimal scenario, IHC would peak in 2025 and decrease to 10.07 × 106 ton in 2060; this scenario can effectively mitigate household carbon emissions by reducing carbon emission intensity and the share of RES consumption; at the same time, it can ensure a sustained increase in per capita consumption. The results unveil the pathways of household carbon reduction under the dual-carbon target in Fujian province and suggest the local government should adopt policies (such as taxation and financial incentives) to limit residential consumptions with high carbon emission intensity.
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Dióxido de Carbono , Carbono , Humanos , Dióxido de Carbono/análise , Carbono/análise , China , Habitação , População Rural , Desenvolvimento EconômicoRESUMO
PURPOSE: Myopia is the most prevalent refractive error, imposing a substantial economic burden. Physical indicators constitute significant influencing factors for myopia. The National Health and Nutrition Examination Survey (NHANES) investigates the health and nutritional status of both children and adults in the United States. This study leveraged NHANES to explore the association between physical indicators and myopia among American adolescents. DESIGN: Retrospective case-control study. METHODS: The final study cohort consisted of 9008 adolescents. Demographic data, physical indicators, and vision data were extracted. The association between myopia and demographic factors, as well as physical indicators, employed weighted methods. Regression models were utilized to identify the associations between physical indicators and myopia. Cumulative odds logistic regression analysis was employed to investigate the association between physical indicators and the degree of myopia. Restricted cubic spline analysis was employed to examine the potential nonlinear relationship between physical indicators and the risk of myopia. RESULTS: The occurrence of myopia was significantly correlated with age (P < .001) and race (P = .019). Adolescents in the fourth percentile for weight (odds ratio [OR] 1.38, 95% confidence interval [CI] 1.13-1.70) and body mass index (BMI) (OR 1.26, 95% CI 1.05-1.51) exhibited an increased possibility of myopia. The highest risk of myopia was observed when the BMI approached 30. Height emerged as a risk factor for the degree of myopia (OR 1.02, 95% CI 1.01-1.03). CONCLUSIONS: A certain association existed between physical indicators and myopia. Weight and BMI were related to the occurrence of myopia, while height and race were associated with the degree of myopia.
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Miopia , Adulto , Criança , Humanos , Adolescente , Estados Unidos/epidemiologia , Inquéritos Nutricionais , Estudos Retrospectivos , Estudos de Casos e Controles , Miopia/epidemiologia , Fatores de Risco , PrevalênciaRESUMO
With the continuous growth of the global economy, an increasing concern has emerged among individuals with regard to personal digital health. Smart fiber-based sensors meet people's demands for wearable devices with the advantages of excellent skin-friendliness and breathability, enabling efficient and prompt monitoring of personal digital health signals in daily life. Furthermore, by integrating machine learning and big data analysis techniques, a closed-loop system can be established for personal digital health, covering data collection, data analysis, as well as medical diagnosis and treatment. Herein, we provide a review of the recent research progress on fiber-based wearable sensors for personal digital health. Firstly, a brief introduction is provided to demonstrate the importance of fiber-based wearable sensors in personal digital health. Then, the monitoring of biophysical signals through fiber-based sensors is described, and they are classified based on different sensing principles in biophysical signal monitoring (resistive, capacitive, piezoelectric, triboelectric, magnetoelastic, and thermoelectric). After that, the fiber-based biochemical signal sensors are described through the classification of monitoring targets (biofluids and respiratory gases). Finally, a summary is presented on the application prospects and the prevailing challenges of fiber-based sensors, aiming to implement their future role in constructing personal digital health networks.
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Point-of-care critical ultrasound (POC-CUS) screening plays an increasingly important role in the treatment of critically ill infants. Without POC-CUS, the lives of many infants would not be saved in time and correctly. A premature infant with systemic multiple organ system dysfunction caused by fungal sepsis was treated and nursed under the guidance of POC-CUS monitoring, and the infant was ultimately cured. This premature infant had systemic multiple organ system dysfunction and disseminated intravascular coagulation (DIC) caused by fungal sepsis. In the hypercoagulable state of early-stage DIC, cardiac thrombosis could be found using ultrasound screening. For this case, right renal artery thrombosis was found via renal artery Doppler ultrasound examination. Due to the severity of this disease, ultrasound-guided peripherally inserted central catheter (PICC) insertion and ultrasound checks of the PICC tip's position were performed, which ensured the success of this one-time catheterization and shortened the catheterization time. Lung ultrasound is used for the diagnosis and differential diagnosis of pulmonary diseases, and to guide the application of mechanical ventilation. Because the abdominal circumference of the patient's markedly enlarged abdominal circumference, bloody stool, and absence of bowel sounds, abdominal ultrasonography was performed, which revealed a markedly enlarged liver, significant peritoneal effusion, and necrotizing enterocolitis. Guided by POC-CUS monitoring, we had the opportunity to implement timely and effective treatment that ultimately saved this critically ill patient's life. The successful treatment of this newborn infant fully reflects the importance of carrying out POC-CUS screening.
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BACKGROUND: Child maltreatment has profound effects on mental health. The Childhood Trauma Questionnaire Short Form (CTQ-SF) and the Adverse Childhood Experiences International Questionnaire (ACE-IQ) are commonly used retrospective assessment tools for evaluating child maltreatment. OBJECTIVE: This study aims to conduct a comprehensive comparison of the CTQ-SF and ACE-IQ, encompassing internal consistency, prevalence, and the predictive efficacy of trauma-related outcomes. It also seeks to enhance the scoring method of ACE-IQ based on the established comparability between the two instruments. PARTICIPANTS AND SETTING: 1484 college students from northern China were recruited, assessing demographic characteristics and outcomes related to traumatic experiences, including post-traumatic stress disorder (PTSD), complex post-traumatic stress disorder (CPTSD), borderline personality disorder (BPD), anxiety, and depression. METHODS: A contingency correlation analysis was performed to evaluate the degree of agreement between the CTQ-SF and ACE-IQ. Binary logistic regression models were utilized to compare the predictive capabilities of distinct instruments. RESULTS: CTQ-SF and ACE-IQ instruments display favorable internal consistency and notable correlations across shared categories. However, the predictive relationships between trauma type and adverse outcomes are inconsistent across instruments. The ACE-IQ, encompassing 13 trauma categories, demonstrate a lower AIC and BIC index, indicating a superior model fit for elucidating outcomes. CONCLUSION: This study introduces a scoring methodology for ACE-IQ, improving the comparability of the two measures and emphasizing the importance of capturing the full range of maltreatment types a child may have experienced. These findings have significant implications for clinical and epidemiological research, providing valuable insights for understanding the impact of child maltreatment.
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Maus-Tratos Infantis , Criança , Humanos , Maus-Tratos Infantis/psicologia , Prevalência , Psicometria , Reprodutibilidade dos Testes , Estudos Retrospectivos , Inquéritos e QuestionáriosRESUMO
Industrial parks are the main carriers of industrial activities and are also key areas for carbon emissions. To deeply explore the decoupling state of carbon emissions and economic development of industrial parks and the driving forces, Zhengzhou Economic Development Zone were taken as example, based on the energy consumption data of industrial enterprises above a designated size from 2011 to 2020, the IPCC carbon emission accounting method, Tapio decoupling model, and logarithmic mean Divisia index decomposition method were used to analyze the characteristics of carbon emissions from energy consumption in the park, the relationship between carbon emissions and economic development, and the driving factors of decoupling. The results showed that:â in terms of carbon emission characteristics, the carbon emissions of energy consumption in Zhengzhou Economic Development Zone were mainly indirect carbon emissions, and the total carbon emissions showed a trend of rapid growth in the early stage, slowing down in the medium term, and negative growth in the later stage. The carbon emission intensity was decreasing annually. â¡ From the perspective of decoupling, the decoupling index between total carbon emissions and economic development in Zhengzhou Economic Development Zone from 2011 to 2016 was 1.021, which was in a state of growth linkage, and the decoupling index decreased to 0.089 from 2016 to 2020, turning into a weak decoupling state. ⢠From the analysis of driving factors, from 2011 to 2016, four factors, namely carbon emission coefficient, energy efficiency, industrial structure, and economic level, all had a restraining effect on the decoupling of carbon emissions in Zhengzhou Economic Development Zone, and from 2016 to 2020, they all turned into promotion except for the economic level. This study showed that among the factors for the decoupling of carbon emissions in the Zhengzhou Economic Development Zone, the economic level played a major inhibitory role, and energy efficiency played a major role in promoting it. The results of this study can provide a reference for the industry-city integrated industrial park represented by Zhengzhou Economic Development Zone to formulate corresponding carbon emission reduction policies and achieve the carbon peaking and carbon neutrality goals.