Non-Intrusive Speech Quality Assessment Based on Deep Neural Networks for Speech Communication.

Traditionally, speech quality evaluation relies on subjective assessments or intrusive methods that require reference signals or additional equipment. However, over recent years, non-intrusive speech quality assessment has emerged as a promising alternative, capturing much attention from researchers and industry professionals. This article presents a deep learning-based method that exploits large-scale intrusive simulated data to improve the accuracy and generalization of non-intrusive methods. The major contributions of this article are as follows. First, it presents a data simulation method, which generates degraded speech signals and labels their speech quality with the perceptual objective listening quality assessment (POLQA). The generated data is proven to be useful for pretraining the deep learning models. Second, it proposes to apply an adversarial speaker classifier to reduce the impact of speaker-dependent information on speech quality evaluation. Third, an autoencoder-based deep learning scheme is proposed following the principle of representation learning and adversarial training (AT) methods, which is able to transfer the knowledge learned from a large amount of simulated speech data labeled by POLQA. With the help of discriminative representations extracted from the autoencoder, the prediction model can be trained well on a relatively small amount of speech data labeled through subjective listening tests. Fourth, an end-to-end speech quality evaluation neural network is developed, which takes magnitude and phase spectral features as its inputs. This phase-aware model is more accurate than the model using only the magnitude spectral features. A large number of experiments are carried out with three datasets: one simulated with labels obtained using POLQA and two recorded with labels obtained using subjective listening tests. The results show that the presented phase-aware method improves the performance of the baseline model and the proposed model with latent representations extracted from the adversarial autoencoder (AAE) outperforms the state-of-the-art objective quality assessment methods, reducing the root mean square error (RMSE) by 10.5% and 12.2% on the Beijing Institute of Technology (BIT) dataset and Tencent Corpus, respectively. The code and supplementary materials are available at https://github.com/liushenme/AAE-SQA.

Low-Cost Preparation of High-Performance Na-B-H-S Electrolyte for All-Solid-State Sodium-Ion Batteries.

All-solid-state sodium-ion batteries have the potential to improve safety and mitigate the cost bottlenecks of the current lithium-ion battery system if a high-performance electrolyte with cost advantages can be easily synthesized. In this study, a one-step dehydrogenation-assisted strategy to synthesize the novel thio-borohydride (Na-B-H-S) electrolyte is proposed, in which both raw material cost and preparation temperature are significantly reduced. By using sodium borohydride (NaBH4 ) instead of B as a starting material, B atoms can be readily released from NaBH4 with much less energy and thus became more available to generate thio-borohydride. The synthesized Na-B-H-S (NaBH4 /Na-B-S) electrolyte exhibits excellent compatibility with current cathode materials, including FeF3 (1.0-4.5 V), Na3 V2 (PO4 )3 (2.0-4.0 V), and S (1.2-2.8 V). This novel Na-B-H-S electrolyte will take a place in mainstream electrolytes because of its advantages in preparation, cost, and compatibility with various cathode materials.

Current status, trends, and predictions in the burden of gallbladder and biliary tract cancer in China from 1990 to 2019.

BACKGROUND: Gallbladder and biliary tract cancer (GBTC) has greatly damaged the health of patients and is accompanied by a dismal prognosis. The worldwide distribution of GBTC shows extensive variance and the updated data in China is lacking. This study was to determine the current status, trends, and predictions in the burden of GBTC over the past 30 years in China. METHODS: This was a descriptive, epidemiological, secondary analysis of the Global Burden of Disease, Injuries, and Risk Factor Study 2019 data. Data including incidence, prevalence, mortality, and disability-adjusted life years (DALYs) of GBTC in China by year, age, and sex were assessed. Joinpoint regression analysis was conducted to evaluate trends of disease burden due to GBTC from 1990 to 2019. Nordpred age-period-cohort analysis was applied for the projection of mortality and incidence due to GBTC from 2019 to 2044. RESULTS: Nationally, there were 38,634 (95% uncertainty interval [UI]: 27,350-46,512) new cases and 47,278 (95% UI: 32,889-57,229) patients due to GBTC, causing 34,462 (95% UI: 25,220-41,231) deaths, and 763,584 (95% UI: 566,755-920,493) DALYs in 2019. Both cases and rates of burden owing to GBTC were heavier among males and at old age. From 1990 to 2019, the age-standardized rates of incidence, prevalence, mortality, and DALYs of GBTC generally increased from 1990 to 2019, with average annual percentage change at 0.8% (95% confidential interval [CI]: 0.6-1.0%), 1.3% (95% CI: 1.1-1.5%), 0.4% (95% CI: 0.2-0.6%), and 0.2% (95% CI: 0.1-0.4%), respectively. Even though the age-standardized incidence rate and age-standardized mortality rate in both sexes were predicted to decline gradually from 2019 to 2044, the number of new cases and deaths were expected to grow steadily. CONCLUSIONS: GBTC is becoming a major health burden in China, particularly among males and older individuals. Given the aging population and increasing burden, effective strategies and measurements are urged to prevent or reduce the number of new cases and deaths of GBTC.

Burden of pancreatitis and associated risk factors in China, 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019.

BACKGROUND: Pancreatitis is a common disease of the digestive system. Acute pancreatitis is one of the most common reasons for gastrointestinal hospital admission, and chronic pancreatitis significantly reduces quality of life. However, national epidemiological data on pancreatitis in China are lacking. This study aimed to quantify the disease burden of pancreatitis in China from 1990 to 2019. METHODS: This study was based on the Global Burden of Disease Study 2019 dataset. Age-standardized rates of incidence (ASIR), prevalence (ASPR), mortality (ASMR), and disability-adjusted life years (DALYs) were used to describe the disease burden of pancreatitis, and estimated annual percentage change (EAPC) was used to indicate the average change in age-standardized rates. We also described the trend of pancreatitis-related mortality and DALYs, which are attributable to alcohol use by age and sex. RESULTS: From 1990 to 2019, the ASIR, ASPR, ASMR, and age-standardized DALYs of pancreatitis in China decreased by 10.90, 1.50, 0.49, and 15.54 per 100,000, respectively, with EAPCs of -1.35 (95% uncertainty interval [UI]: -1.67, -1.02) and -0.37 (95% UI: -0.43, -0.31), -2.01 (95% UI: -2.07, -1.94) and -2.32 (95% UI: -2.37, -2.28), respectively. Recently, the numbers of incident and prevalent cases have risen, with estimates of 380,018 (95% UI: 308,669-462,767) and 493,765 (95% UI: 416,705-578,675), respectively, in 2019. Among men, the disease burden of pancreatitis was more severe than among women, and with variances in the distribution among different age groups. Age-standardized DALYs caused by alcohol-related pancreatitis have gradually worsened in the past decade, accounting for 34.09% of the total in 2019. CONCLUSIONS: The disease burden of pancreatitis in China has declined in the past 30 years, but the exacerbation of population aging poses a challenge to prevention and control of pancreatitis. Alcohol use has gradually become an important factor in the disease burden of pancreatitis in recent years.

Global and national burden and trends of mortality and disability-adjusted life years for silicosis, from 1990 to 2019: results from the Global Burden of Disease study 2019.

BACKGROUND: Silicosis, as an important type of pneumoconiosis, leads to progressive and irreversible conditions from the beginning of inflammation and fibrosis. However, the data on the global burden of silicosis and long-term trends were limited. METHODS: Derived from the Global Burden of Disease study 2019 (online publicly available: Global Health Data Exchange), data on both crude and age-standardized rates (ASR) per 100,00 people of mortality and disability-adjusted life years (DALYs) due to silicosis was collected and analyzed. The burden and trends of mortality and DALYs due to silicosis was assessed by 204 countries and territories, by 5-year interval of age group and by sex from 1990 to 2019. And all the regions were divided into 5 categories according to Sociodemographic Index (SDI). Temporal trends in mortality and DALY were evaluated only to ASR by the Joinpoint regression model. RESULTS: More than 12.9 thousand [95% Uncertainty Intervals (UI): 10.9, 16.2] death cases occurred due to silicosis worldwide, and 655.7 thousand (95% UI: 519.3, 828.0) DALYs were attributed to silicosis in 2019. From 1990 to 2019, global number of mortality and DALYs in countries with high SDI quintile decreased by 0.35% (95% UI: - 0.45, - 0.17) and 0.32% (95% UI: - 0.45, - 0.01), respectively. There was a greater burden in low- and middle-income countries were estimated in 2019 according to ASRs. The global number of mortality and DALYs among males accounted for over 95% of all in 2019. Both age-sex-specific mortality and DALY rate were increasing with aging and reached their peak at 85-89 age group. During the past 30 years, ASR of mortality and DALYs showed a decreasing trend with average annual percentage change at -3.0% [95% Confidence Intervals (CI): - 3.2, - 2.9] and - 2.0 (95% CI: - 1.7, - 2.2), respectively. CONCLUSIONS: Silicosis remains an important health issue and causes a potentially serious burden worldwide. Attention should be paid to making preventable, affordable and effective measures in lower SDI regions.

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The development of ecological economy is one of the core elements of the ecological civilization system and an essential means to optimize the social-ecological systems. The key to developing ecological economy lies in preparing the development plan to realize concrete implementation. Given the objective and realistic demand for the development of ecological economy, it is critically needed to propose the approach of eco-economic planning and conduct empirical research. We sorted out the connotation of ecological economy, proposed the general idea of "object identification-resource evaluation-principal construction-target setting-task content-mechanism guarantee", and proposed three work modules, including "preliminary preparation, content design, review & approval", and finally built a technical system for the preparation of provincial-scale ecological economy planning. We outlined the 14th Five-Year Plan for Eco-Economic Development of Liaoning Province, and discussed critical issues such as the connotation definition and index system establishment for eco-economic development plan. This work provides ideas for the scientific and standardized preparation of ecological economy development plan at the provincial level in China.

In Situ Quality Assessment of Dried Sea Cucumber (Stichopus japonicus) Oxidation Characteristics during Storage by iKnife Rapid Evaporative Ionization Mass Spectrometry.

Sea cucumber (Stichopus japonicus) is one of the most luxurious and nutritious seafoods in Asia. It is always processed into dried products to prevent autolysis, but its quality is easily destructed during storage. Herein, an extremely simplified workflow was established for real-time and in situ quality assessment of dried sea cucumbers (DSCs) during storage based on the lipid oxidation characteristics using an intelligent surgical knife (iKnife) coupled with rapid evaporative ionization mass spectrometry (REIMS). The lipidomic phenotypes of DSCs at different storage times were acquired successfully, which were then processed by multivariate statistical analysis. The results showed that the discrepancy in the characteristic ions in different DSCs was significant (p < 0.05) with high R2(Y) and Q2 values (0.975 and 0.986, respectively). The receiver operating characteristic curve revealed that the ions of m/z 739.5, m/z 831.5, m/z 847.6, and m/z 859.6 were the most specific and characteristic candidate biomarkers for quality assessment of DSCs during accelerated storage. Finally, this method was validated to be qualified in precision (RSDintraday ≤ 9.65% and RSDinterday ≤ 9.36%). In conclusion, the results showed that the well-established iKnife-REIMS method was high-throughput, rapid, and reliable in the real-time quality assessment of DSCs.

Malnutrition Is an Independent Risk Factor for Low Health-Related Quality of Life Among Centenarians.

Background: To explore the association and understand gender disparities between nutritional status and quality of life among centenarians. Methods: It was a full-sample survey of centenarians conducted in Hainan that included a total of 1,002 eligible centenarians whose age had been verified. The Mini Nutritional Assessment - Short Form (MNA-SF) questionnaire and the EuroQol five dimensions visual analog scale (EQ-5D-VAS) were used to measure participants' nutritional status and quality of life, respectively. Findings: In the 1002 centenarians (822 women and 180 men), 797 (79.5%) (79.5%) reported multimorbidity. The adjusted standardized ß estimate association between the MNA-SF and EQ-5D scores was 0.508 in the complete sample. With reference to the normal nutrition group, the standardized ß estimate of the association between EQ-5D score and nutritional status were -0.179 and -0.583 for the at risk of malnutrition and malnutrition groups, respectively (both P <0.001). Nutritional status significantly affected the five dimensions of quality of life, particularly mobility and self-care. Compared with the normal nutrition group, the malnutrition group had greater odds of low mobility [Odds ratio (OR)=23.15; 95% CI: 9.81-54.64] and low self-care (OR=24.58; 95% CI: 12.62-47.89). Among males, nutritional status was significantly associated with the usual activities and anxiety/depression dimensions after adjustment. Female participants had results similar to the general population. Interpretation: Malnutrition and being at risk of malnutrition is prevalent among centenarians. Maintaining normal nutritional status is an important protective factor and should receive more attention to improve centenarians' quality of life.

Reduced medical spending associated with integrated pharmacy benefits.

OBJECTIVES: Although pharmacy benefit carve-outs are promoted as a cost-containment tool, their impact on medical spending is not well understood. We compare the health care spending of Blue Cross and Blue Shield of Louisiana (BCBSLA) members covered by an integrated ("carved-in") pharmacy benefit with that of members covered under a pharmacy benefit carve-out. STUDY DESIGN: Matched, longitudinal cohort study. METHODS: We identified members with coverage through an employer contracting for administrative services only (ie, self-insured) and determined whether they received a pharmacy benefit through BCBSLA. We matched members with and without integrated benefits using a baseline year and compared their medical spending trajectories in 3 subsequent years. These comparisons were repeated in the subset of patients with chronic comorbidities. RESULTS: Among patients with chronic illnesses, relative growth in per-member per-month (PMPM) medical spending was significantly lower in the integrated benefit group by the second and third follow-up years. Neither the level nor the growth of PMPM medical spending significantly differed in the full population sample, although point estimates suggest that the integrated benefit members may be on a lower cost growth trajectory over time. CONCLUSIONS: Members with chronic illnesses receiving an integrated pharmacy benefit experienced slower medical cost growth compared with members covered by a pharmacy carve-out. Group leaders and brokers should consider the additional cost savings achieved by integrated pharmacy benefits when comparing the total costs of carve-in vs carve-out prescription drug programs.

Association of co-pay elimination with medication adherence and total cost.

OBJECTIVES: To determine whether elimination of co-pays for prescription drugs affects medication adherence and total health care spending. STUDY DESIGN: Retrospective comparative study. METHODS: We conducted a difference-in-differences comparison in the year before and after expansion of a Zero Dollar Co-pay (ZDC) prescription drug benefit in commercially insured Louisiana residents. Blue Cross and Blue Shield of Louisiana members with continuous disease management program enrollment were analyzed, of whom 6463 were enrolled in the ZDC program and 1821 were controls who were ineligible because their employers did not opt in. RESULTS: After ZDC expansion, medication adherence fell in the control group and rose in the ZDC group, with a relative increase of 2.1 percentage points (P = .002). Medical spending fell by $71 per member per month (PMPM) (P = .027) in the ZDC group relative to controls. Overall, there was no significant increase in the cost of drugs between treatment and controls. However, when drugs were further categorized, there was a significant increase of $8 PMPM for generic drugs and no significant difference for brand name drugs. Comparisons of medication adherence rates by household income showed the largest relative increase post ZDC expansion among low-income members. CONCLUSIONS: Elimination of co-pays for drugs indicated to treat chronic illnesses was associated with increases in medication adherence and reductions in overall spending of $63. Benefit designs that eliminate co-pays for patients with chronic illnesses may improve adherence and reduce the total cost of care.

Portfolio optimization in the era of digital financialization using cryptocurrencies.

The Fourth industrial revolution has seen many innovative technologies that are now challenging traditional economies. The innovative and technological financial instruments are inspiring individuals and expert investors to investigate the broader investment spectrum, and consequently diversify their portfolios. Going beyond the conventional portfolios and developing state-of-the-art strategies that comply with the ever-changing financial and technological advancements are the keys to long term sustainability. Therefore, to cater to the needs of all segments of the society, the investment strategies during the fourth industrial revolution demand exposure to technological and digital financial innovations. This study investigates the impact of diversification with the addition of five cryptocurrencies from November 2015 to November 2019 on four traditional asset portfolios. The results show that the diversification increased the returns in most of the cases, and reduced the portfolio volatility in all portfolios, and also provided higher returns as compared to the traditional portfolios for the same level of risk. This study also revealed that the results might improve when short sales are allowed. Moreover, we can conclude that the addition of multiple cryptocurrencies in a portfolio provides enhanced results for diversification, and Ethereum provides a better diversification opportunity as compared to Bitcoin.

How Do Economic Growth, Urbanization, and Industrialization Affect Fine Particulate Matter Concentrations? An Assessment in Liaoning Province, China.

With China's rapid development, urban air pollution problems occur frequently. As one of the principal components of haze, fine particulate matter (PM2.5) has potential negative health effects, causing widespread concern. However, the causal interactions and dynamic relationships between socioeconomic factors and ambient air pollution are still unclear, especially in specific regions. As an important industrial base in Northeast China, Liaoning Province is a representative mode of social and economic development. Panel data including PM2.5 concentration and three socio-economic indicators of Liaoning Province from 2000 to 2015 were built. The data were first-difference stationary and the variables were cointegrated. The Granger causality test was used as the main method to test the causality. In the results, in terms of the causal interactions, economic activities, industrialization and urbanization processes all showed positive long-term impacts on changes of PM2.5 concentration. Economic growth and industrialization also significantly affected the variations in PM2.5 concentration in the short term. In terms of the contributions, industrialization contributed the most to the variations of PM2.5 concentration in the sixteen years, followed by economic growth. Though Liaoning Province, an industry-oriented region, has shown characteristics of economic and industrial transformation, policy makers still need to explore more targeted policies to address the regional air pollution issue.

Value-based insurance design in Louisiana: Blue Cross Blue Shield's Zero Dollar Co-pay program.

OBJECTIVES: To determine whether a program that eliminated pharmacy co-pays, the Blue Cross Blue Shield of Louisiana (BCBSLA) Zero Dollar Co-pay (ZDC) program, decreased health care spending. Previous studies have found that value-based insurance designs like the ZDC program have little or no impact on total health care spending. ZDC included an expansive set of medications related to 4 chronic diseases rather than a limited set of medications for 1 or 2 chronic diseases. Additionally, ZDC focused on the most at-risk patients. STUDY DESIGN: ZDC began in 2014 and enrolled patients over time based on (1) when a patient answered a call from a nurse care manager and (2) when a patient or their employer changed the benefit structure to meet the program criteria. During 2015 and 2016, 265 patients with at least 1 chronic condition (asthma, diabetes, hypertension, mental illness) enrolled in ZDC. METHODS: Observational study using within-patient variation and variation in patient enrollment month to identify the impact of the ZDC program on health spending measures. We used 100% BCBSLA claims data from January 2015 to June 2018. Monthly level event studies were used to test for differential spending patterns prior to ZDC enrollment. RESULTS: We found that total spending decreased by $205.9 (P = .049) per member per month, or approximately 18%. We saw a decrease in medical spending ($195.0; P = .023) but did not detect a change in pharmacy spending ($7.59; P = .752). We found no evidence of changes in spending patterns prior to ZDC enrollment. CONCLUSIONS: The ZDC program provides evidence that value-based insurance designs that incorporate a comprehensive set of medications and focus on populations with chronic disease can reduce spending.

Soil heavy metal contamination assessment in the Hun-Taizi River watershed, China.

The Hun-Taizi River watershed includes the main part of the Liaoning central urban agglomeration, which contains six cities with an 80-year industrial history. A total of 272 samples were collected from different land use areas within the study area to estimate the concentration levels, spatial distributions and potential sources of arsenic (As), cadmium (Cd), chromium (Cr), copper (Cu), mercury (Hg), nickel (Ni), lead (Pb) and zinc (Zn) with a geographic information system (GIS), principal component analysis (PCA) and canonical correspondence analysis (CCA). Only the concentration of Cd was over the national standard value (GB 15618-2018). However, the heavy metal concentrations at 24.54%, 71.43%, 63.37%, 85.71, 70.33%, 53.11%, and 72.16% of the sampling points were higher than the local soil background values for As, Cd, Cr, Cu, Hg, Ni, Pb and Zn, respectively, which were used as standard values in this study. The maximal values of Cd (16.61 times higher than the background value) and Hg (12.18 times higher than the background value) had high concentrations, while Cd was present in the study area at higher values than in some other basins in China. Cd was the primary pollutant in the study area due to its concentration and potential ecological risk contribution. The results of the potential ecological risk index (RI) calculation showed that the overall heavy metal pollution level of the soil was considerably high. Three groups of heavy metals with similar distributions and sources were identified through PCA. The results of the CCA showed that the distribution of mines was the strongest factor affecting the distributions of Ni, As, Zn, Pb, and Cd. However, Cu was strongly influenced by the distance to the nearest river. These findings can provide scientific support for critical planning and strategies for soil pollution control and removal to support the sustainable development of the study area.

Higher Normal Levels of Triglyceride and Low and High-Density Lipoprotein Cholesterol Might Have a Protective Effect Against Activities of Daily Living Disability Within Chinese Female Centenarians: A Cross-Sectional, Complete Sample Study.

BACKGROUND AND OBJECTIVE: Activities of daily living (ADL) disability seriously affects the quality of life in the elderly. This study aims to examine the prevalence of ADL disability and its possible correlation with lipid profile indicators (LDL-C, TG and HDL-C) among female centenarians in Hainan, China. METHODS: A cross-section of complete sample study including 822 female centenarians was conducted from the China Hainan Centenarians Cohort Study (CHCCS) from June 2014 to December 2016. Barthel index was used to estimate ADL disability and multivariate logistic regression model was used to explore the relationship between lipid profile indicator and ADL disability. RESULTS: A total of 822 female centenarians were recruited in Hainan province, and the median age was 102 (IQR: 101-104) years, and 244 (29.7%) centenarians had ADL disability. After adjustment, 1 mmol/L increment in LDL-C, TG and HDL-C were associated with 26.4% (aOR=0.736, 95% CI:0.592-0.915), 29.8% (aOR=0.702, 95% CI:0.521-0.948) and 60.5% (aOR=0.395, 95% CI:0.257-0.610) decline in ADL disability of female centenarian, respectively. The prevalence of ADL disability showed downward trend with the increase of the quintile of LDL-C, TG and HDL-C (Ptrend<0.05). Increment of HDL-C levels had the strongest protective effect against ADL disability. CONCLUSION: We concluded that a new possible association of higher normal lipid profile indicators, especially HDL-C, might have a protective effect on ADL disability among female centenarians.

[Extraction of land-cover and wetland area in Bohai Rim region based on Google Earth Engine.] / 基于Google Earth Engine的环渤海地区土地覆盖分类.

The land cover of Bohai Rim region has changed greatly due to urbanization and economic development. Monitoring the land cover with high accuracy and real time is the most important basis for relevant researches. Traditional single-machine processing mode is difficult to realize rapid monitoring for large-scale and long-time series. The emergence of remote sensing big data makes it possible to combine computing platform and massive data. The land cover maps of study area were interpreted based on Google Earth Engine (GEE) platform with decision tree (CART) method from 2000 to 2019. The land cover change was analyzed, and the interpretation results using different data sources were compared. The results showed that the GEE platform could realize the rapid land cover interpretation in a large area, which interpreted coastal wetlands and other cover types with high accuracy over 80% comparing the surveyed points. Compared with Landsat images, the Sentinel-2A images interpretation results had a great improvement in accuracy, which increased from 85% to 95%, and thus more detailed surface information could be reflected. In 2000, the area of wetland, build-up area, farmland, forest, and water in the study area were 1612.5, 5734.9, 32074.8, 11853 and 3504.3 km2, accounting for 2.9%, 10.5%, 58.6%, 21.6% and 6.4% respectively. By 2019, wetlands had been reduced by 775.1 km2, with a decline of 40.1%; built-up area increased by 5310.5 km2 with an increasing rate of 92.6%. The area of farmland, forestland and water area decreased 1841.6, 1823.5 and 870.3 km2, with a decreasing rate of 5.7%, 24.8% and 48.1%, respectively. The coastal urbanization process caused the occupation of built-up area to other land use types, which was the main driving force of land cover change in the study area.

Association between chronic obstructive pulmonary disease and activity of daily living among oldest-old in China: based on Chinese Longitudinal Health Longevity Survey.

Aims: This study was designed to investigate the association between COPD and activity of daily living among oldest-old in People's Republic of China. Patients and methods: The data of Chinese Longitudinal and Health Longevity Study in 2014 was used, and those who were aged more than 80 years old were included. Both basic activity of daily living (BADL) and instrumental activity of daily living (IADL) were measured. Results: A total of 4621 oldest-old (≥80 years old) were included. 32.1% (1482) of the oldest-old had BADL disability and 79.0% (3129) had IADL disability. The BADL disability and IADL disability rates were higher for participants with COPD than those without, and this difference was more robust among male (31.8% vs 25.6%, p=0.018). The IADL disability rate showed similar trends. Multivariate logistic regression analysis showed that the odds ratios of COPD on BADL disability and IADL disability were 1.261 (95% CI: 1.044-1.525) and 2.014 (95% CI: 1.561-2.598), respectively. The odds ratios of COPD on moderate to severe BADL disability and IADL disability were 1.007 (95% CI: 0.790-1.284) and 1.713 (95% CI: 1.397-2.100), respectively. Conclusion: There were independent associations between COPD and disability among oldest-old in People's Republic of China, and the associations were greater among male population. Besides, COPD had a profound influence on the mild disability of BADL, while had a greater impact on the moderate and severe disability of IADL.

Spatiotemporal Pattern of Fine Particulate Matter and Impact of Urban Socioeconomic Factors in China.

Frequent hazy weather has been one of the most obvious air problems accompanying China's rapid urbanization. As one of the main components of haze pollution, fine particulate matter (PM2.5), which severely affects environmental quality and people's health, has attracted wide attention. This study investigated the PM2.5 distribution, changing trends and impact of urban factors based on remote-sensing PM2.5 concentration data from 2000 to 2015, combining land-use data and socioeconomic data, and using the least-squares method and structural equation model (SEM). The results showed that the high concentration of PM2.5 in China was mainly concentrated in the eastern part of China and Sichuan Province. The trends of the PM2.5 concentration in eastern part and Northeast China, Sichuan, and Guangxi Provinces were positive. Meanwhile, the ratios of increasing trends were strongest in built-up land and agricultural land, and the decreasing trends were strongest in forest and grassland, but the overall trends were still growing. The SEM results indicated that economic factors contributed most to PM2.5 pollution, followed by demographic factors and spatial factors. Among all observed variables, the secondary industrial GDP had the highest impact on PM2.5 pollution. Based on the above results, PM2.5 pollution remains an important environmental issue in China at present and even in the future. It is necessary for decision-makers to make actions and policies from macroscopic and microscopic, long-term and short-term aspects to reduce pollution.

Exploring Health Information Sharing Behavior Among Chinese Older Adults: A Social Support Perspective.

This study investigated the determinants of health information sharing behaviors of Chinese older adults living in rural areas. Drawing upon a widely used categorization of social support, we tested the effect of social embeddedness and perceived social support on health information sharing behavior, which is conceptualized as a type of enacted social support-informational support. Data were collected between June and August 2014 from 387 older Chinese adults aged 60-79 years in Linxi County of northern China. The results of hierarchical ordinary least squares regression analyses revealed that Chinese older adults' perceived social support from families and social embeddedness were positively associated with health information sharing behavior, net of the influence of social demographic controls and health information seeking and scanning behaviors. Furthermore, health information sharing behavior was also found to be positively associated with health information seeking and scanning behaviors. Overall, this study enriched the existing literature on health information sharing behavior by taking a social support perspective. A number of practical implications were also discussed.

Evaluating the Hydrologic Performance of Low Impact Development Scenarios in a Micro Urban Catchment.

As urbanization progresses, increasingly impervious surfaces have changed the hydrological processes in cities and resulted in a major challenge for urban stormwater control. This study uses the urban stormwater model to evaluate the performance and costs of low impact development (LID) scenarios in a micro urban catchment. Rainfall-runoff data of three rainfall events were used for model calibration and validation. The pre-developed (PreDev) scenario, post-developed (PostDev) scenario, and three LID scenarios were used to evaluate the hydrologic performance of LID measures. Using reduction in annual runoff as the goal, the best solutions for each LID scenario were selected using cost-effectiveness curves. The simulation results indicated that the three designed LID scenarios could effectively reduce annual runoff volumes and pollutant loads compared with the PostDev scenario. The most effective scenario (MaxPerf) reduced annual runoff by 53.4%, followed by the sponge city (SpoPerf, 51.5%) and economy scenarios (EcoPerf, 43.1%). The runoff control efficiency of the MaxPerf and SpoPerf scenarios increased by 23.9% and 19.5%, respectively, when compared with the EcoPerf scenario; however, the costs increased by 104% and 83.6%. The reduction rates of four pollutants (TSS, TN, TP, and COD) under the MaxPerf scenario were 59.8-61.1%, followed by SpoPerf (53.9-58.3%) and EcoPerf (42.3-45.4%), and the costs of the three scenarios were 3.74, 3.47, and 1.83 million yuan, respectively. These results can provide guidance to urban stormwater managers in future urban planning to improve urban water security.