The accuracy and reliability of different midsagittal planes in the symmetry assessment using cone-beam computed tomography.

Symmetry is an essential component of esthetic assessment. Accurate assessment of facial symmetry is critical to the treatment plan of orthognathic surgery and orthodontic treatment. However, there is no internationally accepted midsagittal plane (MSP) for orthodontists and orthognathic surgeons. The purpose of this study was to explore a clinically friendly MSP, which is more accurate and reliable than what is commonly used in symmetry assessment. Forty patients with symmetric craniofacial structures were analyzed on cone-beam computed tomography (CBCT) scans. The CBCT data were exported to the Simplant Pro software to build four reference planes that were constructed by nasion (N), basion (Ba), sella (S), odontoid (Dent), or incisive foramen (IF). A total of 31 landmarks were located to determine which reference plane is the most optimal MSP by comparing the asymmetry index (AI). The mean value of AI showed a significant difference (p < 0.05) among four reference planes. Also, the mean value of AI for all landmarks showed that Plane 2 (consisting of N, Ba, and IF) and Plane 4 (consisting of N, IF, and Dent) were more accurate and stable. In conclusion, the MSP consisting of N, Dent, and IF shows more accuracy and reliability than the other planes. Further, it is more clinically friendly because of its significant advantage in landmarking.

Evaluating the Effectiveness of Regional Ecological Civilization Policy: Evidence from Jiangsu Province, China.

Evaluating the effectiveness of ecological civilization policies is the basis from which policymakers can optimize policies. From the perspective of the overall effectiveness of regional policies, and taking Jiangsu Province as an example, this study constructed a quantitative evaluation model of eco-civilization policy text and an eco-civilization evaluation index system. Using these tools, this paper evaluates the effectiveness of 53 ecological civilization policies issued by Jiangsu Province during 2004-2019 to promote the construction of ecological civilization in the four fields of resource utilization, environmental protection, economic development, and social life. There are three key findings. (1) During the period of 2004-2019, the effectiveness of the textual content of ecological civilization policies in Jiangsu Province generally showed a fluctuating upward trend. (2) The construction effectiveness indexes of the four fields of eco-civilization all showed a growth trend, but the construction effect varied greatly. The index of economic development had grown rapidly, while environmental protection had grown slowly. (3) Ecological civilization policies in Jiangsu Province were effective in promoting the construction of ecological civilization. However, the effects of different policy dimensions on ecological civilization development in the four fields were significantly different. Finally, based on these results, powerful recommendations are provided for the optimization of eco-civilization policies in Jiangsu Province. Moreover, Jiangsu is the first province in China to launch a provincial-level ecological civilization construction plan. Its policy optimization to promote ecological civilization construction can also provide an example and realistic basis for reference for the construction of eco-civilization in other provinces in China.

Using RNA-Seq to Explore the Repair Mechanism of the Three Methods and Three-Acupoint Technique on DRGs in Sciatic Nerve Injured Rats.

Objective: To study the effects of the three methods and three-acupoint technique on DRG gene expression in SNI model rats and to elucidate the molecular mechanism of the three methods and three-acupoint technique on promoting recovery in peripheral nerve injury. Methods: 27 male SD rats were randomly divided into three groups: a Sham group, the SNI group, and the Tuina group. The Tuina group was treated with a tuina manipulation simulator to simulate massage on points, controlling for both quality and quantity. Point-pressing, plucking, and kneading methods were administered quantitatively at Yinmen (BL37), Chengshan (BL57), and Yanglingquan (GB34) points on the affected side once a day, beginning 7 days after modeling. Intervention was applied once a day for 10 days, then 1 day of rest, followed by 10 more days of intervention, totally equaling 20 times of intervention. The effect of the three methods and three-point technique on the recovery of injured rats was evaluated using behavior analysis. RNA sequencing (RNA-Seq) analysis of differentially expressed genes in DRGs of the three groups of rats was also performed. GO and KEGG enrichment was analyzed and verified using real-time PCR. Results: RNA-Seq combined with database information showed that the number of differentially expressed genes in DRG was the largest in the Tuina group compared with the SNI group, totaling 226. GO function is enriched in the positive regulation of cell processes, ion binding, protein binding, neuron, response to pressure, response to metal ions, neuron projection, and other biological processes. GO function is also enriched in the Wnt, IL-17, and MAPK signaling pathways in the KEGG database. PCR results were consistent with those of RNA sequencing, suggesting that the results of transcriptome sequencing were reliable. Conclusion: The three methods and three-acupoint technique can promote the recovery of SNI model rats by altering the gene sequence in DRGs.

Assessing the effect of non-financial information intervention on promoting group-level energy savings.

Increasing attention has been paid to information intervention in stimulating household energy conservation. However, for group-level energy users who have no financial motivation to save energy, little is known about which types of non-financial information intervention (NFII) strategies can effectively motivate group-level energy conservation. A 14-week controlled field experiment was conducted to test the energy-saving effect of 4 types of NFII strategies. The results show that compared with the control group, the experimental group receiving normative information and group-contrast feedback decreased electricity consumption by 24.23%. Followed by the group receiving normative information and self-contrast feedback and the group receiving environmental education information and group-contrast feedback. The group receiving environmental education information and self-contrast feedback showed no significant energy savings. Analysis of variance further showed that normative information had a better energy-saving effect than environmental education information, and the energy-saving effects produced by group-contrast feedback were better than that of self-contrast feedback. These conclusions provide insights and recommendations on how to use NFII to motivate group-level energy conservation.