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2.
Artigo em Inglês | MEDLINE | ID: mdl-38194390

RESUMO

Automatic identification of visual learning style in real time using raw electroencephalogram (EEG) is challenging. In this work, inspired by the powerful abilities of deep learning techniques, deep learning-based models are proposed to learn high-level feature representation for EEG visual learning identification. Existing computer-aided systems that use electroencephalograms and machine learning can reasonably assess learning styles. Despite their potential, offline processing is often necessary to eliminate artifacts and extract features, making these methods unsuitable for real-time applications. The dataset was chosen with 34 healthy subjects to measure their EEG signals during resting states (eyes open and eyes closed) and while performing learning tasks. The subjects displayed no prior knowledge of the animated educational content presented in video format. The paper presents an analysis of EEG signals measured during a resting state with closed eyes using three deep learning techniques: Long-term, short-term memory (LSTM), Long-term, short-term memory-convolutional neural network (LSTM-CNN), and Long-term, short-term memory-Fully convolutional neural network (LSTM-FCNN). The chosen techniques were based on their suitability for real-time applications with varying data lengths and the need for less computational time. The optimization of hypertuning parameters has enabled the identification of visual learners through the implementation of three techniques. LSTM-CNN technique has the highest average accuracy of 94%, a sensitivity of 80%, a specificity of 92%, and an F1 score of 94% when identifying the visual learning style of the student out of all three techniques. This research has shown that the most effective method is the deep learning-based LSTM-CNN technique, which accurately identifies a student's visual learning style.


Assuntos
Aprendizado Profundo , Humanos , Redes Neurais de Computação , Eletroencefalografia/métodos , Aprendizado de Máquina , Artefatos
3.
Rheumatol Int ; 35(1): 1-16, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-24879325

RESUMO

Early detection of knee osteoarthritis (OA) is of great interest to orthopaedic surgeons, rheumatologists, radiologists, and researchers because it would allow physicians to provide patients with treatments and advice to slow the onset or progression of the disease. Early detection can be achieved by identifying early changes in selected features of degenerative articular cartilage (AC) using non-invasive imaging modalities. Magnetic resonance imaging (MRI) is becoming the standard for assessment of OA. The aim of this paper was to review the influence of MRI on the selection, detection, and measurement of AC features associated with early OA. Our review of the literature indicates that the changes associated with early OA are in cartilage thickness, cartilage volume, cartilage water content, and proteoglycan content that can be accurately, consistently, and non-invasively measured using MRI. Choosing an MR pulse sequence that provides the capability to assess cartilage physiology and morphology in a single acquisition and advanced multi-nuclei MRI is desirable. The results of the review indicate that using an ultra-high magnetic strength, MR imager does not affect early OA detection. In conclusion, MRI is currently the most suitable modality for early detection of knee OA, and future research should focus on the quantitative evaluation of early OA features using advances in MR hardware, software, and data processing with sophisticated image/pattern recognition techniques.


Assuntos
Cartilagem Articular/patologia , Imageamento por Ressonância Magnética/métodos , Osteoartrite do Joelho/patologia , Progressão da Doença , Humanos , Processamento de Imagem Assistida por Computador , Articulação do Joelho/patologia , Índice de Gravidade de Doença
4.
Acad Radiol ; 22(1): 93-104, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25481518

RESUMO

RATIONALE AND OBJECTIVES: Quantitative assessment of knee articular cartilage (AC) morphology using magnetic resonance (MR) imaging requires an accurate segmentation and 3D reconstruction. However, automatic AC segmentation and 3D reconstruction from hydrogen-based MR images alone is challenging because of inhomogeneous intensities, shape irregularity, and low contrast existing in the cartilage region. Thus, the objective of this research was to provide an insight into morphologic assessment of AC using multilevel data processing of multinuclear ((23)Na and (1)H) MR knee images. MATERIALS AND METHODS: A dual-tuned ((23)Na and (1)H) radio-frequency coil with 1.5-T MR scanner is used to scan four human subjects using two separate MR pulse sequences for the respective sodium and proton imaging of the knee. Postprocessing is performed using customized routines written in MATLAB. MR data were fused to improve contrast of the cartilage region that is further used for automatic segmentation. Marching cubes algorithm is applied on the segmented AC slices for 3D volume rendering and volume is then calculated using the divergence theorem. RESULTS: Fusion of multinuclear MR images results in an improved contrast (factor >3) in the cartilage region. Sensitivity (80.21%) and specificity (99.64%) analysis performed by comparing manually segmented AC shows a good performance of the automated AC segmentation. The average cartilage volume (23.19 ± 1.38 cm(3); coefficient of variation [COV] -0.059) measured from 3D AC models of four data sets shows a marked improvement over average cartilage volume (23.24 cm(3); COV -0.19) reported earlier. CONCLUSIONS: This study confirms the use of multinuclear MR data for cartilage morphology (volume) assessment that can be used in clinical settings.


Assuntos
Cartilagem Articular/anatomia & histologia , Cartilagem Articular/metabolismo , Articulação do Joelho/anatomia & histologia , Articulação do Joelho/metabolismo , Imageamento por Ressonância Magnética/métodos , Espectroscopia de Prótons por Ressonância Magnética/métodos , Sódio/metabolismo , Feminino , Humanos , Aumento da Imagem/métodos , Masculino , Compostos Radiofarmacêuticos/farmacocinética , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Isótopos de Sódio/farmacocinética
5.
Biomed Eng Online ; 13: 109, 2014 Aug 03.
Artigo em Inglês | MEDLINE | ID: mdl-25087016

RESUMO

BACKGROUND: Subcutaneous veins localization is usually performed manually by medical staff to find suitable vein to insert catheter for medication delivery or blood sample function. The rule of thumb is to find large and straight enough vein for the medication to flow inside of the selected blood vessel without any obstruction. The problem of peripheral difficult venous access arises when patient's veins are not visible due to any reason like dark skin tone, presence of hair, high body fat or dehydrated condition, etc. METHODS: To enhance the visibility of veins, near infrared imaging systems is used to assist medical staff in veins localization process. Optimum illumination is crucial to obtain a better image contrast and quality, taking into consideration the limited power and space on portable imaging systems. In this work a hyperspectral image quality assessment is done to get the optimum range of illumination for venous imaging system. A database of hyperspectral images from 80 subjects has been created and subjects were divided in to four different classes on the basis of their skin tone. In this paper the results of hyper spectral image analyses are presented in function of the skin tone of patients. For each patient, four mean images were constructed by taking mean with a spectral span of 50 nm within near infrared range, i.e. 750-950 nm. Statistical quality measures were used to analyse these images. CONCLUSION: It is concluded that the wavelength range of 800 to 850 nm serve as the optimum illumination range to get best near infrared venous image quality for each type of skin tone.


Assuntos
Luz , Imagem Óptica/métodos , Pigmentação da Pele , Pele/irrigação sanguínea , Veias , Humanos
6.
Artigo em Inglês | MEDLINE | ID: mdl-24110124

RESUMO

In mental stress studies, cerebral activation and autonomic nervous system are important distinctly. This study aims to analyze disparities associated with scalp potential, which may have impact on autonomic activation of heart during mental stress. Ten healthy subjects participated in this study that performed arithmetic tasks in stress and control environment. Task difficulty was calculated from their correct responses. During the experiment, electroencephalogram (EEG) and electrocardiogram (ECG) signals were recorded concurrently. Sympathetic innervation of heart was estimated from heart rate (HR), which is extracted from the ECG. The value of theta Fz/alpha Pz was measured from EEG scalp potential. The results show a significant surge in the value of theta Fz/alpha Pz in stress as compared to baseline (p<0.013) and control (p<0.042). The results also present tachycardia while in stress as compared to baseline (p<0.05). Task difficulty in stress is also considerably higher than control environment (p<0.003).


Assuntos
Estresse Psicológico/fisiopatologia , Análise e Desempenho de Tarefas , Adulto , Sistema Nervoso Autônomo/fisiologia , Eletrocardiografia/métodos , Eletroencefalografia/métodos , Voluntários Saudáveis , Frequência Cardíaca/fisiologia , Humanos , Masculino , Couro Cabeludo/fisiologia , Adulto Jovem
7.
Magn Reson Imaging ; 31(7): 1059-67, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23731535

RESUMO

Osteoarthritis is a common joint disorder that is most prevalent in the knee joint. Knee osteoarthritis (OA) can be characterized by the gradual loss of articular cartilage (AC). Formation of lesion, fissures and cracks on the cartilage surface has been associated with degenerative AC and can be measured by morphological assessment. In addition, loss of proteoglycan from extracellular matrix of the AC can be measured at early stage of cartilage degradation by physiological assessment. In this case, a biochemical phenomenon of cartilage is used to assess the changes at early degeneration of AC. In this paper, a method to measure local sodium concentration in AC due to proteoglycan has been investigated. A clinical 1.5-T magnetic resonance imaging (MRI) with multinuclear spectroscopic facility is used to acquire sodium images and quantify local sodium content of AC. An optimised 3D gradient-echo sequence with low echo time has been used for MR scan. The estimated sodium concentration in AC region from four different data sets is found to be ~225±19mmol/l, which matches the values that has been reported for the normal AC. This study shows that sodium images acquired at clinical 1.5-T MRI system can generate an adequate quantitative data that enable the estimation of sodium concentration in AC. We conclude that this method is potentially suitable for non-invasive physiological (sodium content) measurement of articular cartilage.


Assuntos
Cartilagem Articular/patologia , Joelho/patologia , Imageamento por Ressonância Magnética/métodos , Osteoartrite do Joelho/patologia , Sódio/química , Calibragem , Cartilagem/patologia , Desenho de Equipamento , Humanos , Processamento de Imagem Assistida por Computador/métodos , Imageamento Tridimensional/métodos , Imagens de Fantasmas , Proteoglicanas/química
8.
Skin Res Technol ; 18(1): 1-14, 2012 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-21605170

RESUMO

INTRODUCTION: This paper presents a comprehensive review of acne grading and measurement. Acne is a chronic disorder of the pilosebaceous units, with excess sebum production, follicular epidermal hyperproliferation, inflammation and Propionibacterium acnes activity. Most patients are affected with acne vulgaris, which is the prevalent type of acne. Acne vulgaris consists of comedones (whitehead and blackhead), papules, pustules, nodules and cysts. OBJECTIVES: To review and identify the issues for acne vulgaris grading and computational assessment methods. To determine the future direction for addressing the identified issues. METHODS: There are two main methods of assessment for acne severity grading, namely, lesion counting and comparison of patient with a photographic standard. For the computational assessment method, the emphasis is on computational imaging techniques. RESULTS: Current acne grading methods are very time consuming and tedious. Generally, they rely on approximation for counting lesions and hence the assessment is quite subjective, with both inter and intra-observer variability. It is important to accurately assess acne grade to evaluate its severity as this influences treatment selection and assessment of response to therapy. This will further help in better disease management and more efficacious treatment. CONCLUSION: Semi-automated or automated methods based on computational imaging techniques should be devised for acne grade assessment.


Assuntos
Acne Vulgar/classificação , Acne Vulgar/diagnóstico , Dermoscopia/métodos , Interpretação de Imagem Assistida por Computador/métodos , Fotografação/métodos , Índice de Gravidade de Doença , Humanos
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