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Sci Rep ; 11(1): 16064, 2021 08 09.
Artigo em Inglês | MEDLINE | ID: mdl-34373475

RESUMO

The EUROMACS Right-Sided Heart Failure Risk Score was developed to predict right ventricular failure (RVF) after left ventricular assist device (LVAD) placement. The predictive ability of the EUROMACS score has not been tested in other cohorts. We performed a single center analysis of a continuous-flow (CF) LVAD cohort (n = 254) where we calculated EUROMACS risk scores and assessed for right ventricular heart failure after LVAD implantation. Thirty-nine percent of patients (100/254) had post-operative RVF, of which 9% (23/254) required prolonged inotropic support and 5% (12/254) required RVAD placement. For patients who developed RVF after LVAD implantation, there was a 45% increase in the hazards of death on LVAD support (HR 1.45, 95% CI 0.98-2.2, p = 0.066). Two variables in the EUROMACS score (Hemoglobin and Right Atrial Pressure to Pulmonary Capillary Wedge Pressure ratio) were not predictive of RVF in our cohort. Overall, the EUROMACS score had poor external discrimination in our cohort with area under the curve of 58% (95% CI 52-66%). Further work is necessary to enhance our ability to predict RVF after LVAD implantation.


Assuntos
Insuficiência Cardíaca/patologia , Ventrículos do Coração/patologia , Disfunção Ventricular Direita/patologia , Idoso , Estudos de Coortes , Feminino , Coração Auxiliar , Humanos , Masculino , Pessoa de Meia-Idade , Implantação de Prótese/métodos , Pressão Propulsora Pulmonar/fisiologia , Medição de Risco/métodos , Fatores de Risco
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