The Influence of Sex and/or Gender on the Occurrence of Colorectal Cancer in the General Population in Developed Countries: A Scoping Review.

Objective: Gender as the "sociocultural role of sex" is underrepresented in colorectal cancer incidence studies, potentially resulting in underestimated risk factors' consequences and inequalities men/women. We aim to explore how literature focusing on differences between men and women in the incidence of colorectal cancer interprets these differences: through sex- or gender-related mechanisms, or both? Methods: We conducted a scoping review using PubMed and Google Scholar. We categorized studies based on their definitions of sex and/or gender variables. Results: We reviewed 99 studies, with 7 articles included in the analysis. All observed differences between men and women. Six articles examined colorectal cancer incidence by gender, but only 2 used the term "gender" to define exposure. One article defined its "sex" exposure variable as gender-related mechanisms, and two articles used "sex" and "gender" interchangeably to explain these inequalities. Gender mechanisms frequently manifest through health behaviors. Conclusion: Our results underscore the need for an explicit conceptual framework to disentangle sex and/or gender mechanisms in colorectal cancer incidence. Such understanding would contribute to the reduction and prevention of social health inequalities.

Half-quadratic cost function for computing arbitrary phase shifts and phase: Adaptive out of step phase shifting.

We present a phase shifting robust method for irregular and unknown phase steps. The method is formulated as the minimization of a half-quadratic (robust) regularized cost function for simultaneously computing phase maps and arbitrary phase shifts. The convergence to, at least, a local minimum is guaranteed. The algorithm can be understood as a phase refinement strategy that uses as initial guess a coarsely computed phase and coarsely estimated phase shifts. Such a coarse phase is assumed to be corrupted with artifacts produced by the use of a phase shifting algorithm but with imprecise phase steps. The refinement is achieved by iterating alternated minimization of the cost function for computing the phase map correction, an outliers rejection map and the phase shifts correction, respectively. The method performance is demonstrated by comparison with standard filtering and arbitrary phase steps detecting algorithms.