Return to work after sick leave due to musculoskeletal disorder or injury: a longitudinal study conducted in Brazil.

BACKGROUND: Musculoskeletal disorders and injuries (MSDI) are conditions that affect the locomotor system characterized by pain and impairment of functionality. They are the leading cause of years lived with disability. The aim of this study was to analyze the factors that influence the return to work (RTW) among workers on sick leave due to MSDI.   METHODS: A longitudinal study was conducted in the city of São Paulo, Brazil, between 2020-2022. The participants were 216 workers who required social security compensation due to MSDI. They filled out online questionnaires about their sociodemographic characteristics, health risk behaviors, work characteristics and health conditions. They were followed for 365 days after their first day of sick leave. A Cox regression was performed to identify the factors that influenced their first RTW. RESULTS: Most participants were male (53.0%), mean age was 39.5 years (SD 10.6), 70.4% returned to work within the one-year follow-up period. The mean duration of sick leave was 192.6 days. Factors associated with a lower RTW were age 40 years and older (HR 0.54; 95%CI 0.39-0.76) and the interaction between perceptions of the need for improvement in the physical and psychological domains of quality of life (HR 0.67; 95%CI 0.48-0.94). CONCLUSIONS: Occupational healthcare professionals should pay greater attention to patients who are aging and those with perceived worse physical and psychological conditions, in order to facilitate the reintegration process and promote sustained RTW after sick leave due to musculoskeletal disorder or injury.

Validity and reliability of the Brazilian version of the Johns Hopkins Fall Risk Assessment Tool to assess the risk of falls. / Validade e confiabilidade da versão brasileira da Johns Hopkins Fall Risk Assessment Tool para avaliação do risco de quedas.

OBJECTIVE: To evaluate the validity and reliability of the Johns Hopkins Fall Risk Assessment Tool (JH-FRAT), which assesses the risk of falls in hospitalized inpatients. METHOD: Study with 297 patients at a hospital in São Paulo, using retrospective data form 2014. Validity was assessed by accuracy (sensitivity, specificity, positive predictive value - PPV and negative predictive value - NPV) and discriminant analysis (comparison of patients with and without falls in relation to the scale items and comparison of previous risk situations in relation to the injury). The χ2 test and Fisher's exact test were used. Reliability was assessed by reproducibility between methods and interobserver test-retest comparison in a subsample of 60 patients. We used the Kappa, quadratic weighted Kappa and PABAK statistics. RESULTS: Sensitivity was 97.0%, specificity was 6%, PPV was 36.2% and NPV was 90.6%. Five of the eight items of the scale and the overall classification showed risk discrimination capability (p < 0.050). The risk of previous situations did not discriminate the injury resulting from the falls (p = 0.557). Reproducibility between methods was substantial (PABAK = 0.71). The interobserver reproducibility ranged between items (PABAK 0.25 to 1.00) and was substantial to the overall risk classification (PABAK = 0.71). CONCLUSION: JH-FRAT showed validity and reliability expected of a screening tool for risk of falls, and it can contribute to the implementation of fall management strategies in hospitals.

OBJETIVO: Avaliar a validade e a confiabilidade da escala Johns Hopkins Fall Risk Assessment Tool (JH-FRAT) para avaliação do risco de quedas em pacientes hospitalizados. MÉTODO: Estudo retroativo com 297 pacientes de um hospital privado de São Paulo usando dados de 2014. A validade foi avaliada por meio da acurácia (sensibilidade, especificidade, valores preditivos positivo - VPP e negativo - VPN), da validade de critério, verificando-se as associações entre a classificação do risco pelas escalas JH-FRAT e Morse, e da análise discriminante (comparação dos pacientes com e sem quedas em relação aos itens da escala e verificação de situações prévias de risco em relação ao dano ocorrido). Foram utilizados os testes de associação χ2. A confiabilidade foi avaliada por meio da reprodutibilidade teste-reteste interobservadores, usando as estatísticas Kappa ponderado quadrático e prevalence-adjusted and bias-adjusted Kappa (PABAK). RESULTADOS: A sensibilidade foi de 97,0%, a especificidade, 14,6%, o VPP, 36,2%, e o VPN, 90,6%. A análise de critério mostrou associação (p < 0,0001) entre as avaliações pelas duas escalas. Cinco dos oito itens da escala e a classificação geral mostraram capacidade de discriminação do risco (p < 0,050). A reprodutibilidade interobservadores variou entre itens (PABAK de 0,25 a 1,00) e foi substancial na classificação do risco global (PABAK = 0,71). CONCLUSÃO: A JH-FRAT apresentou validade e confiabilidade esperadas para um instrumento de triagem do risco de quedas, podendo contribuir na aplicação de estratégias para a gestão de quedas em hospitais.

Validade e confiabilidade da versão brasileira da Johns Hopkins Fall Risk Assessment Tool para avaliação do risco de quedas / Validity and reliability of the Brazilian version of the Johns Hopkins Fall Risk Assessment Tool to assess the risk of falls

RESUMO: Objetivo: Avaliar a validade e a confiabilidade da escala Johns Hopkins Fall Risk Assessment Tool (JH-FRAT) para avaliação do risco de quedas em pacientes hospitalizados. Método: Estudo retroativo com 297 pacientes de um hospital privado de São Paulo usando dados de 2014. A validade foi avaliada por meio da acurácia (sensibilidade, especificidade, valores preditivos positivo - VPP e negativo - VPN), da validade de critério, verificando-se as associações entre a classificação do risco pelas escalas JH-FRAT e Morse, e da análise discriminante (comparação dos pacientes com e sem quedas em relação aos itens da escala e verificação de situações prévias de risco em relação ao dano ocorrido). Foram utilizados os testes de associação χ2. A confiabilidade foi avaliada por meio da reprodutibilidade teste-reteste interobservadores, usando as estatísticas Kappa ponderado quadrático e prevalence-adjusted and bias-adjusted Kappa (PABAK). Resultados: A sensibilidade foi de 97,0%, a especificidade, 14,6%, o VPP, 36,2%, e o VPN, 90,6%. A análise de critério mostrou associação (p < 0,0001) entre as avaliações pelas duas escalas. Cinco dos oito itens da escala e a classificação geral mostraram capacidade de discriminação do risco (p < 0,050). A reprodutibilidade interobservadores variou entre itens (PABAK de 0,25 a 1,00) e foi substancial na classificação do risco global (PABAK = 0,71). Conclusão: A JH-FRAT apresentou validade e confiabilidade esperadas para um instrumento de triagem do risco de quedas, podendo contribuir na aplicação de estratégias para a gestão de quedas em hospitais.

ABSTRACT: Objective: To evaluate the validity and reliability of the Johns Hopkins Fall Risk Assessment Tool (JH-FRAT), which assesses the risk of falls in hospitalized inpatients. Method: Study with 297 patients at a hospital in São Paulo, using retrospective data form 2014. Validity was assessed by accuracy (sensitivity, specificity, positive predictive value - PPV and negative predictive value - NPV) and discriminant analysis (comparison of patients with and without falls in relation to the scale items and comparison of previous risk situations in relation to the injury). The χ2 test and Fisher's exact test were used. Reliability was assessed by reproducibility between methods and interobserver test-retest comparison in a subsample of 60 patients. We used the Kappa, quadratic weighted Kappa and PABAK statistics. Results: Sensitivity was 97.0%, specificity was 6%, PPV was 36.2% and NPV was 90.6%. Five of the eight items of the scale and the overall classification showed risk discrimination capability (p < 0.050). The risk of previous situations did not discriminate the injury resulting from the falls (p = 0.557). Reproducibility between methods was substantial (PABAK = 0.71). The interobserver reproducibility ranged between items (PABAK 0.25 to 1.00) and was substantial to the overall risk classification (PABAK = 0.71). Conclusion: JH-FRAT showed validity and reliability expected of a screening tool for risk of falls, and it can contribute to the implementation of fall management strategies in hospitals.

Transcultural adaptation of the Johns Hopkins Fall Risk Assessment Tool.

OBJECTIVE: to perform the transcultural adaptation and content validity analysis of the Johns Hopkins Fall Risk Assessment Tool to assess both fall risk and fall-related injury risk for hospitalized elderly in Brazil. METHOD: the transcultural adaptation consisted of translating the scale to Portuguese (Brazil), back-translating it into its language of origin, establishing a consensus version, and having an expert committee verify its transcultural equivalence. Content assessment was conducted by a committee of judges, ending with the calculation of the items and scales' content validity index. Nurses tested the tool. RESULTS: the scale's translated version went through two evaluation rounds by the judges, based on which, the items with unsatisfactory performance were changed. The content validity index for the items was ≥80.0% and the global index 97.1%. The experimental application showed the scale is user-friendly. CONCLUSION: the scale presents valid content for the assessment of fall risk and risk of fall-related injuries and is easy to use, with the potential to contribute to the proper identification of risks and the establishment of care actions.

Cost-Effectiveness Analysis of Different Sequences of the Use of Epidermal Growth Factor Receptor Inhibitors for Wild-Type KRAS Unresectable Metastatic Colorectal Cancer.

PURPOSE: Patients with unresectable wild-type KRAS metastatic colorectal cancer benefit from fluoropyrimidines (FP), oxaliplatin (O), irinotecan (I), bevacizumab (Bev), and epithelial growth factor receptor inhibitors (EGFRI). The most cost-effective regimen remains unclear. METHODS: A Markov model was constructed to examine the costs and outcomes of three treatment strategies: strategy A (reference strategy): EGFRI monotherapy in third line ([3L]; ie, first-line [1L]: Bev + FOLFIRI [FP + I] or FOLFOX [FP + O]; second line [2L]: FOLFIRI/FOLFOX; 3L: EGFRI); strategy B: EGFRI and I in 3L (ie, 1L: Bev + FOLFIRI/FOLFOX; 2L: FOLFIRI/FOLFOX; 3L: EGFRI + I); and strategy C: EGFRI in 1L (ie, 1L: EGFRI + FOLFIRI/FOLFOX; 2L: Bev + FOLFIRI/FOLFOX; 3L: best supportive care). Efficacy data of the treatments were obtained from the literature. Health system resource use information was derived from chart review and the literature. Using Euro-QOL 5 Dimensions, utilities were obtained by surveying medical oncologists and costs from the Ontario Ministry of Health and the literature. The perspective of the Canadian public health care system was used over a 5-year time horizon with a 5% discount in 2012 Canadian dollars. RESULTS: All three strategies had similar efficacy, but strategy C was most expensive. The incremental cost-effectiveness ratios (ICERs) for strategies B and C compared with A were 119,623 and 3,176,591, respectively. The model was primarily driven by the acquisition cost of the drugs. Strategy B was most cost effective when the willingness-to-pay threshold was > $130,000 per quality-adjusted life-year. Sensitivity analysis showed that strategy C would be cost-effective only when the progression-free survival of EGFRI is better than Bev in 1L with hazard ratio < 0.23 at willingness-to-pay of $150,000 per quality-adjusted life-year. CONCLUSION: First-line use of EGFRI in metastatic colorectal cancer is not cost effective at its current pricing relative to Bev.

Transcultural adaptation of the Johns Hopkins Fall Risk Assessment Tool / Adaptação transcultural da Johns Hopkins Fall Risk Assessment Tool para avaliação do risco de quedas / Adaptación transcultural de la Johns Hopkins Fall Risk Assessment Tool para evaluación del riesgo de caídas

ABSTRACT Objective: to perform the transcultural adaptation and content validity analysis of the Johns Hopkins Fall Risk Assessment Tool to assess both fall risk and fall-related injury risk for hospitalized elderly in Brazil. Method: the transcultural adaptation consisted of translating the scale to Portuguese (Brazil), back-translating it into its language of origin, establishing a consensus version, and having an expert committee verify its transcultural equivalence. Content assessment was conducted by a committee of judges, ending with the calculation of the items and scales' content validity index. Nurses tested the tool. Results: the scale's translated version went through two evaluation rounds by the judges, based on which, the items with unsatisfactory performance were changed. The content validity index for the items was ≥80.0% and the global index 97.1%. The experimental application showed the scale is user-friendly. Conclusion: the scale presents valid content for the assessment of fall risk and risk of fall-related injuries and is easy to use, with the potential to contribute to the proper identification of risks and the establishment of care actions.

RESUMO Objetivo: realizar a adaptação transcultural para uso no Brasil e a avaliação da validade de conteúdo da Johns Hopkins Fall Risk Assessment Tool para avaliação de risco de quedas e de danos por quedas em pacientes adultos hospitalizados. Método: adaptação transcultural consistiu na tradução da escala para a língua portuguesa (Brasil), retrotradução para a língua de origem, versão de consenso e análise da equivalência transcultural por um comitê de especialistas. A avaliação do conteúdo foi realizada por meio de um comitê de juízes, finalizando com o cálculo do índice de validade de conteúdo dos itens e da escala. Foi realizada a aplicação experimental do instrumento por enfermeiros. Resultados: a versão traduzida da escala passou por duas rodadas de avaliação pelos juízes, a partir das quais os itens com desempenho insatisfatório foram modificados. O índice de validade de conteúdo para itens foi ≥80,0% e o global foi 97,1%. A aplicação experimental mostrou que a escala é de fácil operacionalização. Conclusão: a escala demonstrou conteúdo válido para a avaliação de risco de quedas e de danos por quedas e ser de fácil operacionalização, podendo contribuir para a adequada identificação dos riscos e consequente direcionamento de ações assistenciais.

RESUMEN Objetivo: realizar la adaptación transcultural para ser usada en Brasil y confirmar la validez de contenido de la Johns Hopkins Fall Risk Assessment Tool que evalúa riesgo de caídas y de daños por caídas en pacientes adultos mayores. Método: adaptación transcultural que consistió en la traducción de la escala para el idioma portugués (Brasil); retrotraducción para el idioma de origen; y versión de consenso y análisis de la equivalencia transcultural por un comité de especialistas. La evaluación del contenido fue realizada por medio de un comité de jueces, siendo finalizado con el cálculo del índice de validez de contenido de los ítems y de la escala. Fue realizada la aplicación experimental del instrumento por enfermeros. Resultados: la versión traducida de la escala pasó por dos vueltas de evaluación por los jueces, a partir de las cuales los ítems con desempeño insatisfactorio fueron modificados. El índice de validez de contenido para los ítems fue ≥80,0% y el global fue 97,1%. La aplicación experimental mostró que la escala es de fácil ejecución. Conclusión: la escala demostró tener un contenido válido para la evaluación de riesgo de caídas y de daños por caídas, y de ser de fácil ejecución; esta escala puede contribuir para la adecuada identificación de los riesgos y consecuentemente para la orientación de acciones asistenciales.

[Factors associated with labor capacity in electric industry workers]. / Fatores associados à capacidade para o trabalho de trabalhadores do Setor Elétrico.

The Brazilian electric utility sector has recently undergone major industrial restructuring, with impacts on working conditions and work organization that could jeopardize the capacity for work. This study aimed to evaluate factors associated with labor capacity in a sample of 475 workers from an electric utility company in the State of São Paulo, Brazil. This cross-sectional study included descriptive and multiple linear regression analyses. The mean labor capacity index (LCI) was 41.8 points (on a scale from 7.0 to 49.0). Multiple regression showed that the factors that best explained LCI variability were work stress (p < 0.001) and physical health (p < 0.001 in all the dimensions). In a separate analysis, excluding all the health dimensions, the variables associated with LCI were work stress (p < 0.001), workplace (p = 0.022), physical activity (p = 0.001), alcohol consumption (p = 0.012), and body mass index (p < 0.001). The results highlighted aspects to be considered when developing measures to protect labor capacity, with an emphasis on stress prevention and health promotion.

Fatores associados à capacidade para o trabalho de trabalhadores do Setor Elétrico / Factors associated with labor capacity in electric industry workers

O Setor Elétrico passou por recente processo de reestruturação produtiva com reflexos nas condições e organização do trabalho, podendo comprometer a capacidade para o trabalho. Este estudo objetivou avaliar fatores associados à capacidade para o trabalho junto a 475 trabalhadores de uma empresa do Setor Elétrico no Estado de São Paulo, Brasil. Neste estudo transversal foi realizada análise descritiva e análise de regressão linear múltipla. A média do Índice de Capacidade para o Trabalho (ICT) foi de 41,8 pontos (escala de 7,0 a 49,0 pontos). A análise múltipla mostrou que os fatores que melhor explicaram a variabilidade do ICT foram estresse no trabalho (p < 0,001) e saúde física (p < 0,001 em todas as dimensões). Em outra análise, excluídas as dimensões da saúde, as variáveis associadas ao ICT foram estresse no trabalho (p < 0,001), local de trabalho (p = 0,022), prática de atividade física (p = 0,001), consumo de álcool (p = 0,012) e índice de massa corporal (p < 0,001). Os resultados identificaram aspectos a serem considerados no desenvolvimento de medidas visando a preservação da capacidade para o trabalho, com ênfase no controle do estresse no trabalho e na promoção da saúde.

The Brazilian electric utility sector has recently undergone major industrial restructuring, with impacts on working conditions and work organization that could jeopardize the capacity for work. This study aimed to evaluate factors associated with labor capacity in a sample of 475 workers from an electric utility company in the State of São Paulo, Brazil. This cross-sectional study included descriptive and multiple linear regression analyses. The mean labor capacity index (LCI) was 41.8 points (on a scale from 7.0 to 49.0). Multiple regression showed that the factors that best explained LCI variability were work stress (p < 0.001) and physical health (p < 0.001 in all the dimensions). In a separate analysis, excluding all the health dimensions, the variables associated with LCI were work stress (p < 0.001), workplace (p = 0.022), physical activity (p = 0.001), alcohol consumption (p = 0.012), and body mass index (p < 0.001). The results highlighted aspects to be considered when developing measures to protect labor capacity, with an emphasis on stress prevention and health promotion.

[Health and work ability among office workers]. / Saúde e capacidade para o trabalho em trabalhadores de área administrativa.

OBJECTIVE: To identify dimensions of health associated with work ability and to verify whether such relationships are influenced by demographic or occupational characteristics. METHODS: A cross-sectional study was carried out, including 224 employees of an employee health insurance and retirement savings company in the city of São Paulo, Brazil, in 2001. Subjects responded to self-administered questionnaires evaluating demographic and occupational characteristics, job satisfaction, health, and work ability. Associations between variables were measured using Chi-square tests, analysis of variance, and analysis of covariance. RESULTS: Occupational and demographic variables significantly associated with work ability were time in job (p=0.0423) and job satisfaction (p=0.0072). All dimensions of health evaluated were significantly associated with work ability (p<0.0001), and were independent of demographic and occupational characteristics. CONCLUSIONS: Results showed that, independently of other characteristics, better physical and mental health are associated with greater work ability. This provides evidence of the importance of considering health in all its dimensions.

Estudo dos fatores associados à capacidade para o trabalho em trabalhadores do setor elétrico / Study of the factors associated with work ability in eletric sector workers

Introdução- A capacidade para o trabalho é influenciada por vários fatores, incluindo a condição de saúde, características sócio-demográficas, estilo de vida e fatores relacionados ao trabalho. Objetivo- Analisar os fatores associados à capacidade para o trabalho em uma população de eletricitários. Métodos- Estudo transversal onde foram analisados 475 trabalhadores, voluntários, de uma empresa privada no setor eletricitário do Estado de São Paulo, Brasil. Os dados foram coletados por meio de questionários auto-preenchidos (Índice de Capacidade para o Trabalho - ICT, Escala Estresse no Trabalho - EET, Medical Outcomes Study 36 - Item short from health survey - SF-36, Questionário de Baecke, Questionário de tolerância de Fagerstrom e Questionário AUDIT). A relação entre variáveis foi analisada por meio do coeficiente de correlação de Spearman, e para comparação das médias foram utilizados os testes Mann-Whitney e Kruskal-Wallis. A análise conjunta das variáveis foi feita por meio de regressão linear múltipla. Resultados- Foi identificada uma diminuição progressiva do valor do ICT significativamente associada aos aumentos de idade (r=-0,16, p<0,001), do índice de massa corporal (r=-0,17, p<0,001), do consumo de álcool (r=-0,11, p=0,019), do tempo na empresa (r=-0,17, p<0,001) e da intensidade do estresse no trabalho (r=-0,37, p,0,001). O valor do ICT apresentou elevação associada ao incremento da prática de atividade física (r=0,19, p<0,001). A média do valor do ICT esteve associada à unidade de trabalho (p=0,043). O ICT esteve associado significativamente com as diversas dimensões do estado de saúde físico e mental (p<0,001 em todas as dimensões). A análise múltipla, ajustada por sexo e tempo na empresa, evidenciou que os fatores que melhor explicaram a variação do ICT foram o estresse no trabalho e as dimensões da saúde física. Uma segunda análise excluídas as dimensões da saúde, mostrou que o estresse no trabalho, a unidade de trabalho e características do es...

[Relationship between psychosocial job satisfaction and health in white collar workers]. / Relação entre satisfação com aspectos psicossociais e saúde dos trabalhadores.

OBJECTIVE: To identify whether psychosocial satisfaction at work is associated with workers' health and to verify if sociodemographic characteristics have an impact on these associations. METHODS: A cross-sectional study was carried out in 224 employees of a private managed care and retirement savings company in São Paulo, Brazil. Four self-administered questionnaires on sociodemographic features, job satisfaction, and health (physical, mental, and work ability) were applied. Variables associations were analyzed using t-Student, Mann-Whitney and Kruskal-Wallis tests, Spearman correlation coefficient, and multiple linear regression analysis. RESULTS: Job satisfaction was associated with duration in the company (p <0.001) and job position (p=0.003), where greater satisfaction was observed among workers with shorter duration in the company and those in managing positions. Job satisfaction was associated with mental health and work ability (vitality: p<0.001; social aspects: p=0.055; emotional aspect: p=0.074; mental health: p<0.001; and work capacity: p=0.001). CONCLUSIONS: Job satisfaction is associated with workers' health regarding their "mental health" and "work ability", showing the importance of psychosocial factors for their health and well-being. Changes are suggested in work conception and organization to focus psychosocial factors. Longitudinal studies are recommended to investigate the causal direction of these associations.