RESUMO
The COVID-19 pandemic has major implications for blood transfusion. There are uncertain patterns of demand, and transfusion institutions need to plan for reductions in donations and loss of crucial staff because of sickness and public health restrictions. We systematically searched for relevant studies addressing the transfusion chain-from donor, through collection and processing, to patients-to provide a synthesis of the published literature and guidance during times of potential or actual shortage. A reduction in donor numbers has largely been matched by reductions in demand for transfusion. Contingency planning includes prioritisation policies for patients in the event of predicted shortage. A range of strategies maintain ongoing equitable access to blood for transfusion during the pandemic, in addition to providing new therapies such as convalescent plasma. Sharing experience and developing expert consensus on the basis of evolving publications will help transfusion services and hospitals in countries at different stages in the pandemic.
Assuntos
Betacoronavirus , Bancos de Sangue/estatística & dados numéricos , Doadores de Sangue/provisão & distribuição , Transfusão de Sangue , Infecções por Coronavirus , Pandemias , Pneumonia Viral , Anticorpos Antivirais/uso terapêutico , Transtornos da Coagulação Sanguínea/etiologia , Transtornos da Coagulação Sanguínea/terapia , Preservação de Sangue , Segurança do Sangue , Transfusão de Sangue/estatística & dados numéricos , COVID-19 , Infecções por Coronavirus/sangue , Infecções por Coronavirus/complicações , Infecções por Coronavirus/prevenção & controle , Infecções por Coronavirus/terapia , Seleção do Doador , Procedimentos Cirúrgicos Eletivos , Alocação de Recursos para a Atenção à Saúde , Política de Saúde , Necessidades e Demandas de Serviços de Saúde , Hemoglobinopatias/complicações , Hemoglobinopatias/terapia , Humanos , Imunização Passiva , Pandemias/prevenção & controle , Pneumonia Viral/sangue , Pneumonia Viral/complicações , Pneumonia Viral/prevenção & controle , Pneumonia Viral/terapia , Ensaios Clínicos Controlados Aleatórios como Assunto , SARS-CoV-2 , Soroterapia para COVID-19RESUMO
A rare case of a low incidence red cell antigen causing severe fetal allo-immune red cell disease is presented. Discussion of how this can be diagnosed and successfully managed antenatally using middle cerebral artery Doppler ultrasound and maternal antibody titre levels for fetal surveillance and timing of intervention with intrauterine transfusion.