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1.
Environ Monit Assess ; 196(6): 519, 2024 May 07.
Artigo em Inglês | MEDLINE | ID: mdl-38713313

RESUMO

Mercury cycling in coastal metropolitan areas on the west coast of India becomes complex due to the combined effects of both intensive domestic anthropogenic emissions and marine air masses. The present study is based on yearlong data of continuous measurements of gaseous elemental mercury (GEM) concentration concurrent with meteorological parameters and some air pollutants at a coastal urban site in Mumbai, on the west coast of India, for the first time. The concentration of GEM was found in a range between 2.2 and 12.3 ng/m3, with a mean of 3.1 ± 1.1 ng/m3, which was significantly higher than the continental background values in the Northern Hemisphere (~ 1.5 ng/m3). Unlike particulates, GEM starts increasing post-winter to peak during the monsoon and decrease towards winter. July had the highest concentration of GEM followed by October, and a minimum in January. GEM exhibited a distinct diurnal cycle, mainly with a broad peak in the early morning, a narrow one by nightfall, and a minimum in the afternoon. The peaks and their timing suggest the origin of urban mobility and the start of local activities. A positive correlation between SO2, PM2.5, temperature, relative humidity, and GEM indicates that emissions from local industrial plants in the Mumbai coastal area. Principal component analysis (PCA) and cluster analysis (CA) confirm this fact. Monthly back trajectory analysis showed that air mass flows are predominantly from the Arabian Sea and local human activities. Assessment of human health risks by USEPA model reveals that the hazardous quotient, HQ < 1, implies negligible carcinogenic risk. GEM observations in Mumbai during the study period are below the World Health Organization's (WHO) safe limit (200 ng/m3) for long-term inhalation.


Assuntos
Poluentes Atmosféricos , Poluição do Ar , Monitoramento Ambiental , Mercúrio , Índia , Poluentes Atmosféricos/análise , Mercúrio/análise , Medição de Risco , Humanos , Poluição do Ar/estatística & dados numéricos , Atmosfera/química , Material Particulado/análise , Cidades
2.
Ann Intern Med ; 177(4): 484-496, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38467001

RESUMO

BACKGROUND: There is increasing concern for the potential impact of health care algorithms on racial and ethnic disparities. PURPOSE: To examine the evidence on how health care algorithms and associated mitigation strategies affect racial and ethnic disparities. DATA SOURCES: Several databases were searched for relevant studies published from 1 January 2011 to 30 September 2023. STUDY SELECTION: Using predefined criteria and dual review, studies were screened and selected to determine: 1) the effect of algorithms on racial and ethnic disparities in health and health care outcomes and 2) the effect of strategies or approaches to mitigate racial and ethnic bias in the development, validation, dissemination, and implementation of algorithms. DATA EXTRACTION: Outcomes of interest (that is, access to health care, quality of care, and health outcomes) were extracted with risk-of-bias assessment using the ROBINS-I (Risk Of Bias In Non-randomised Studies - of Interventions) tool and adapted CARE-CPM (Critical Appraisal for Racial and Ethnic Equity in Clinical Prediction Models) equity extension. DATA SYNTHESIS: Sixty-three studies (51 modeling, 4 retrospective, 2 prospective, 5 prepost studies, and 1 randomized controlled trial) were included. Heterogenous evidence on algorithms was found to: a) reduce disparities (for example, the revised kidney allocation system), b) perpetuate or exacerbate disparities (for example, severity-of-illness scores applied to critical care resource allocation), and/or c) have no statistically significant effect on select outcomes (for example, the HEART Pathway [history, electrocardiogram, age, risk factors, and troponin]). To mitigate disparities, 7 strategies were identified: removing an input variable, replacing a variable, adding race, adding a non-race-based variable, changing the racial and ethnic composition of the population used in model development, creating separate thresholds for subpopulations, and modifying algorithmic analytic techniques. LIMITATION: Results are mostly based on modeling studies and may be highly context-specific. CONCLUSION: Algorithms can mitigate, perpetuate, and exacerbate racial and ethnic disparities, regardless of the explicit use of race and ethnicity, but evidence is heterogeneous. Intentionality and implementation of the algorithm can impact the effect on disparities, and there may be tradeoffs in outcomes. PRIMARY FUNDING SOURCE: Agency for Healthcare Quality and Research.


Assuntos
Algoritmos , Disparidades em Assistência à Saúde , Humanos , Disparidades em Assistência à Saúde/etnologia , Acessibilidade aos Serviços de Saúde , Qualidade da Assistência à Saúde , Etnicidade
3.
J Pediatr ; 270: 114000, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38432295

RESUMO

OBJECTIVE: To assess the relationship between the Child Opportunity Index (COI), a comprehensive measurement of social determinants of health, and specific COI domains on patient-specific outcomes following congenital cardiac surgery in the metropolitan region of Atlanta, Georgia. STUDY DESIGN: In this retrospective chart review, we included patients who underwent an index operation for congenital heart disease between 2010 and 2020 in a single pediatric health care system. Patients' addresses were geocoded and mapped to census tracts. Descriptive statistics, univariable analysis, and multivariable regression models were employed to assess associations between variables and outcomes. RESULTS: Of the 7460 index surgeries, 3798 (51%) met eligibility criteria. Presence of an adverse outcome, defined as either mortality or 1 of several other major postoperative morbidities, was significantly associated with COI in the univariable model (P = .008), but not the multivariable regression model (P = .39). Postoperative hospital length of stay was significantly associated with COI (P < .001) in univariable and multivariable regression models. There was no significant association between COI and readmission within 30 days of hospital discharge in univariable (P < .094) and multivariable (P = .49) models. CONCLUSION: COI is associated with postoperative hospital length of stay but not all outcomes in patients after congenital heart surgery. By understanding the role of COI in outcomes related to cardiac surgery, targeted interventions can be developed to improve health equity.


Assuntos
Procedimentos Cirúrgicos Cardíacos , Cardiopatias Congênitas , Humanos , Estudos Retrospectivos , Masculino , Cardiopatias Congênitas/cirurgia , Feminino , Procedimentos Cirúrgicos Cardíacos/estatística & dados numéricos , Lactente , Pré-Escolar , Criança , Georgia/epidemiologia , Determinantes Sociais da Saúde , Complicações Pós-Operatórias/epidemiologia , Recém-Nascido , Tempo de Internação/estatística & dados numéricos , Adolescente , Readmissão do Paciente/estatística & dados numéricos , Resultado do Tratamento
4.
Health Equity ; 7(1): 773-781, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38076212

RESUMO

Introduction: Despite mounting evidence that the inclusion of race and ethnicity in clinical prediction models may contribute to health disparities, existing critical appraisal tools do not directly address such equity considerations. Objective: This study developed a critical appraisal tool extension to assess algorithmic bias in clinical prediction models. Methods: A modified e-Delphi approach was utilized to develop and obtain expert consensus on a set of racial and ethnic equity-based signaling questions for appraisal of risk of bias in clinical prediction models. Through a series of virtual meetings, initial pilot application, and an online survey, individuals with expertise in clinical prediction model development, systematic review methodology, and health equity developed and refined this tool. Results: Consensus was reached for ten equity-based signaling questions, which led to the development of the Critical Appraisal for Racial and Ethnic Equity in Clinical Prediction Models (CARE-CPM) extension. This extension is intended for use along with existing critical appraisal tools for clinical prediction models. Conclusion: CARE-CPM provides a valuable risk-of-bias assessment tool extension for clinical prediction models to identify potential algorithmic bias and health equity concerns. Further research is needed to test usability, interrater reliability, and application to decision-makers.

5.
Biol Trace Elem Res ; 2023 Nov 04.
Artigo em Inglês | MEDLINE | ID: mdl-37924414

RESUMO

More than 70 million individuals have been exposed to environmental arsenic toxicity, worldwide. United Nation Children's Fund (UNICEF) policy brief -2018 report to mitigate arsenic in drinking water, emphasizes assessing, and changing the knowledge, attitudes, and practices (KAP) as one of the long-term effective solutions to be implemented as a part of surveillance strategies. This study aims to develop a valid and reliable tool to assess knowledge, attitude, and practices of arsenic and its risk in general health. A cross-sectional survey of N=449 general population was conducted in the outpatient department of Rajendra Memorial Research Institute of Medical Sciences-Indian Council for Medical Research for data collection. The construct validation of the questionnaire was done using Exploratory Factor Analysis, Confirmatory factor analysis. The Item-Content Validity Index(I-CVI) and Scale-Content Validity Index (S-CVI) Kappa scores were used to analyze the content validity of the items. The I-CVI ranges from 0.70 to 1, the and the moderate to high cumulative content validity is S-CVI/Universal Agreement=0.84; S-CVI/Average =0.96. Following the principal component analysis, the cumulative Kaiser-Meyer-Olkin measure of sampling adequacy (KMO) was 0.91 and the three domains in the tool (Kaiser-Meyer-Olkin measure of sampling adequacy for Knowledge (0.917), Attitude (0.825) & Practices (0.80)) were within the acceptable range. The Barret's test for sphericity was (P <0.001) and was highly acceptable. The Confirmatory Factor Analysis model of Nu-KAP has demonstrated excellent model fit where, majority of fit indices has sown good fit (X2/df=1.88, Root Mean Square Error of Approximation = 0.04, Comparative Fit Index=0.98, Goodness of Fit Index = 0.93, and Tucker Lewis Index=0.977). The Cronbach's alpha of 19 item tool was 0.72. The Nu-KAPQ questionnaire demonstrated exceptional validity and reliability while also capturing and integrating all pertinent psychometric analytic domains. Conclusively, this questionnaire can be used to assess psychometric properties associated with arsenic bridging the gap in current research to understand people's perception towards arsenic, since it is a crucial component of arsenic mitigation.

6.
Cureus ; 14(10): e30155, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-36397901

RESUMO

BACKGROUND: Toothbrushes may get contaminated by the oral cavity, environment, hands, storage containers, or aerosol contamination. The present study was conducted to assess the microbial contamination of toothbrushes and methods of their decontamination. MATERIALS AND METHODS: The current study included 160 subjects of both genders. All the subjects were provided with a toothbrush and paste with complete hygiene instructions for the oral cavity. After one month, all the brushes were collected. The samples were categorized into four groups of 40 each. Group I was treated with 0.2% chlorhexidine gluconate, group II with Listerine, group III with Dettol, and group IV with tap water. Finally, these toothbrushes were placed in 5 mL of neutralizer broth and then evaluated to study the efficacy of four disinfectants. All the data were analyzed using the statistical package for social science (SPSS) version 23 software (IBM, Armonk, NY, USA). For all analyses, p < 0.05 was considered to be statistically significant Results: Aerobic bacterial growth before disinfection in Groups I, II, III, and IV was 91.6%, 75.84%, 75%, 81.67%, respectively (p = 0.01). After disinfecting the brushes aerobic bacterial growth was reduced to 34.17%, 30.84%, 24.17% & 74.17% in Groups I, II, III, and IV, respectively (p = 0.002). Klebsiella, Micrococci and Escherichia coli survived the most even after disinfection was done. CONCLUSION: Most effective agent for the disinfection of toothbrushes was Dettol followed by Listerine and 0.2% chlorhexidine gluconate. Tap water was found to be ineffective in the decontamination of toothbrushes.

7.
JACC Adv ; 1(2): 100029, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38939312

RESUMO

Background: In the SVR (Single Ventricle Reconstruction) Trial, 1-year survival in recipients of right ventricle to pulmonary artery shunts (RVPAS) was superior to that in those receiving modified Blalock-Taussig-Thomas shunts (MBTTS), but not in subsequent follow-up. Cost analysis is an expedient means of evaluating value and morbidity. Objectives: The purpose of this study was to evaluate differences in cumulative hospital costs between RVPAS and MBTTS. Methods: Clinical data from SVR and costs from Pediatric Health Information Systems database were combined. Cumulative hospital costs and cost-per-day-alive were compared serially at 1, 3, and 5 years between RVPAS and MBTTS. Potential associations between patient-level factors and cost were explored with multivariable models. Results: In total, 303 participants (55% of the SVR cohort) from 9 of 15 sites were studied (48% MBTTS). Observed total costs at 1 year were lower for MBTTS ($701,260 ± 442,081) than those for RVPAS ($804,062 ± 615,068), a difference that was not statistically significant (P = 0.10). Total costs were also not significantly different at 3 and 5 years (P = 0.21 and 0.32). Similarly, cost-per-day-alive did not differ significantly for either group at 1, 3, and 5 years (all P > 0.05). In analyses of transplant-free survivors, total costs and cost-per-day-alive were higher for RVPAS at 1 year (P = 0.05 for both) but not at 3 and 5 years (P > 0.05 for all). In multivariable models, aortic atresia and prematurity were associated with increased cost-per-day-alive across follow-up (P < 0.05). Conclusions: Total costs do not differ significantly between MBTTS and RVPAS. The magnitude of longitudinal costs underscores the importance of efforts to improve outcomes in this vulnerable population.

8.
JAMA Netw Open ; 4(9): e2125846, 2021 09 01.
Artigo em Inglês | MEDLINE | ID: mdl-34542615

RESUMO

Importance: Many strategies to reduce hospital length of stay (LOS) have been implemented, but few studies have evaluated hospital-led interventions focused on high-risk populations. The Agency for Healthcare Research and Quality (AHRQ) Learning Health System panel commissioned this study to further evaluate system-level interventions for LOS reduction. Objective: To identify and synthesize evidence regarding potential systems-level strategies to reduce LOS for patients at high risk for prolonged LOS. Evidence Review: Multiple databases, including MEDLINE and Embase, were searched for English-language systematic reviews from January 1, 2010, through September 30, 2020, with updated searches through January 19, 2021. The scope of the protocol was determined with input from AHRQ Key Informants. Systematic reviews were included if they reported on hospital-led interventions intended to decrease LOS for high-risk populations, defined as those with high-risk medical conditions or socioeconomically vulnerable populations (eg, patients with high levels of socioeconomic risk, who are medically uninsured or underinsured, with limited English proficiency, or who are hospitalized at a safety-net, tertiary, or quaternary care institution). Exclusion criteria included interventions that were conducted outside of the hospital setting, including community health programs. Data extraction was conducted independently, with extraction of strength of evidence (SOE) ratings provided by systematic reviews; if unavailable, SOE was assessed using the AHRQ Evidence-Based Practice Center methods guide. Findings: Our searches yielded 4432 potential studies. We included 19 systematic reviews reported in 20 articles. The reviews described 8 strategies for reducing LOS in high-risk populations: discharge planning, geriatric assessment, medication management, clinical pathways, interdisciplinary or multidisciplinary care, case management, hospitalist services, and telehealth. Interventions were most frequently designed for older patients, often those who were frail (9 studies), or patients with heart failure. There were notable evidence gaps, as there were no systematic reviews studying interventions for patients with socioeconomic risk. For patients with medically complex conditions, discharge planning, medication management, and interdisciplinary care teams were associated with inconsistent outcomes (LOS, readmissions, mortality) across populations. For patients with heart failure, clinical pathways and case management were associated with reduced length of stay (clinical pathways: mean difference reduction, 1.89 [95% CI, 1.33 to 2.44] days; case management: mean difference reduction, 1.28 [95% CI, 0.52 to 2.04] days). Conclusions and Relevance: This systematic review found inconsistent results across all high-risk populations on the effectiveness associated with interventions, such as discharge planning, that are often widely used by health systems. This systematic review highlights important evidence gaps, such as the lack of existing systematic reviews focused on patients with socioeconomic risk factors, and the need for further research.


Assuntos
Tempo de Internação , Alta do Paciente , Medição de Risco/métodos , Fatores Etários , Idoso , Administração de Caso , Procedimentos Clínicos , Avaliação Geriátrica , Insuficiência Cardíaca/terapia , Médicos Hospitalares , Humanos , Equipe de Assistência ao Paciente , Fatores Socioeconômicos , Telemedicina , Estados Unidos , Populações Vulneráveis
9.
Urology ; 154: 62-67, 2021 08.
Artigo em Inglês | MEDLINE | ID: mdl-33476604

RESUMO

OBJECTIVES: To determine contemporary costs of preparing for and applying for a urology residency position for the 2019-2020 American Urological Association Match. METHODS: An electronic survey was emailed to all urology residency applicants who applied to Rutgers Robert Wood Johnson Medical School during the 2019-2020 application cycle; it was sent 2 weeks after the Match results were released. We collected information on applicant demographics, interview logistics, and estimated costs incurred applying to residency. RESULTS: A total of 26% (64/242) of subjects responded, representing all 8 the American Urological Association sections, international schools, and schools without urology programs. 62% were male, 75% were single, and 52% attended public medical school. Applicants paid for the interview trail using loans (67%), family donations (50%), previous or current income (36%), and scholarships (16%). Subjects completed a median of 2 visiting student rotations (IQR 2-3), applied to 80 programs (IQR 66-99), and attended 16 interviews (IQR 13-18.75). The median cost per applicant for the 2019-2020 Match was $9725 (IQR $6134-12,564). This estimate included expenditures on application fees, visiting student rotations, interview trail travel and lodging, research, interview attire, and professional photos. Subjects who attended public medical school were likely to spend $3546.31 (95% confidence interval: 5630.71-1461.916; P < .001) more than those attending private schools. CONCLUSION: Urology residency applicants spend almost $10,000 in pursuit of a residency position. These high costs not only contribute to student debt but also may deter applicants from entering the field of urology.


Assuntos
Estresse Financeiro , Internato e Residência/economia , Candidatura a Emprego , Urologia/educação , Feminino , Humanos , Masculino , Estados Unidos
10.
Indian J Community Med ; 45(3): 323-327, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33354012

RESUMO

BACKGROUND: The World Health Organization (WHO) Child Growth Standards ("WHO Standards") 2007 are the most recent and updated indicators which provide a single international standard that represents the best description of physiological growth for all children. OBJECTIVES: The objective of the study was to estimate the prevalence of malnutrition as per anthropometric indicators, namely underweight, stunting, and wasting among rural children in Raipur district, Chhattisgarh, using the WHO Child Growth Standards. MATERIALS AND METHODS: Nutritional assessment of children was conducted in rural areas using standard anthropometric measurements of height and weight. Totally 10,730 children were screened in 61 schools and 30 Anganwadis belonging to 26 villages across 3 major blocks in Raipur district, Chhattisgarh, during June 2013 to February 2018. Weight-for-age, height-for-age, and body mass index-for-age z-scores were calculated using WHO AnthroPlus software. RESULTS: The prevalence of underweight (≤2 standard deviation) was 45.7% in the children examined. The prevalence of stunting and wasting was 40.4% and 22.0%, respectively. Twenty-two of the 26 villages screened reported malnutrition in more than 30.0% of children, namely every third child lags behind in his or her growth curve despite the Mid-Day Meal Program implemented across the nation including this region since several decades. CONCLUSION: Malnutrition remains an ongoing health problem in school-going children. WHO AnthroPlus software can be very useful for analysis of state- and national-level data of nutritional status of children and could be used to shape health policies for this age group accordingly.

11.
Worldviews Evid Based Nurs ; 16(1): 4-11, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30714308

RESUMO

BACKGROUND: In 2006, our healthcare system created a hospital Evidence-based Practice Center (EPC) to support the local delivery of high-quality, safe and high value patient care. Since then, the importance of healthcare staff work life has also been highlighted, and together these four elements form the Quadruple Aim framework. Synergistic to this Aim, the Magnet® program promotes and recognizes organizational nursing excellence. OBJECTIVE: To examine the EPC's work to inform nursing policy and practice in support of the goals of the Quadruple Aim framework and Magnet® designation. METHODS: Methods used included the following: (1) descriptive analysis of the hospital EPC's database of rapid reviews; and (2) administration of a 40-item electronic questionnaire to nurses who requested an EPC review during fiscal years (FY) 2015 and 2016. RESULTS: Of 308 rapid reviews completed in the EPC's first 10 years, 59 (19%) addressed nursing topics. The proportion of reviews relevant to nursing increased from 5% (2/39) in the center's first 2 years to 44% (25/60) in FY 2015-2016. The majority of nursing reviews (39/59) examined processes of care. Of 23 nurses eligible to participate in the survey, 21 responded (91%). Nurses with administrative or managerial responsibilities requested 70% of reviews; clinical nurse specialists and bedside nurses requested 17% and 9%, respectively. Reviews were used to support clinical program development (48%), provide clinical guidance (33%), update nursing policies or procedures (24%) and develop training and curricula (24%). Nurses were satisfied with the hospital EPC reviews (mean; 4.7/5), and 95% indicated they were likely to request a future review. LINKING EVIDENCE TO ACTION: A dedicated hospital EPC in partnership with nursing offers a unique mechanism for promoting a culture of evidence-based practice. Nurses at all organizational levels use the services of a hospital EPC to inform nursing policy and practice and are highly satisfied with the process, supporting the Quadruple Aim and Magnet® designation.


Assuntos
Prática Clínica Baseada em Evidências/organização & administração , Prática Clínica Baseada em Evidências/normas , Política de Saúde/tendências , Hospitais/tendências , Humanos , Pennsylvania , Desenvolvimento de Programas/métodos , Desenvolvimento de Programas/normas , Inquéritos e Questionários
12.
Pediatr Crit Care Med ; 20(2): 143-148, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30371635

RESUMO

OBJECTIVES: Pediatric cardiac ICUs should be adept at treating both critical medical and surgical conditions for patients with cardiac disease. There are no case-mix adjusted quality metrics specific to medical cardiac ICU admissions. We aimed to measure case-mix adjusted cardiac ICU medical mortality rates and assess variation across cardiac ICUs in the Pediatric Cardiac Critical Care Consortium. DESIGN: Observational analysis. SETTING: Pediatric Cardiac Critical Care Consortium clinical registry. PATIENTS: All cardiac ICU admissions that did not include cardiac surgery. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: The primary endpoint was cardiac ICU mortality. Based on multivariable logistic regression accounting for clustering, we created a case-mix adjusted model using variables present at cardiac ICU admission. Bootstrap resampling (1,000 samples) was used for model validation. We calculated a standardized mortality ratio for each cardiac ICU based on observed-to-expected mortality from the fitted model. A cardiac ICU was considered a statistically significant outlier if the 95% CI around the standardized mortality ratio did not cross 1. Of 11,042 consecutive medical admissions from 25 cardiac ICUs (August 2014 to May 2017), the observed mortality rate was 4.3% (n = 479). Final model covariates included age, underweight, prior surgery, time of and reason for cardiac ICU admission, high-risk medical diagnosis or comorbidity, mechanical ventilation or extracorporeal membrane oxygenation at admission, and pupillary reflex. The C-statistic for the validated model was 0.87, and it was well calibrated. Expected mortality ranged from 2.6% to 8.3%, reflecting important case-mix variation. Standardized mortality ratios ranged from 0.5 to 1.7 across cardiac ICUs. Three cardiac ICUs were outliers; two had lower-than-expected (standardized mortality ratio <1) and one had higher-than-expected (standardized mortality ratio >1) mortality. CONCLUSIONS: We measured case-mix adjusted mortality for cardiac ICU patients with critical medical conditions, and provide the first report of variation in this quality metric within this patient population across Pediatric Cardiac Critical Care Consortium cardiac ICUs. This metric will be used by Pediatric Cardiac Critical Care Consortium cardiac ICUs to assess and improve outcomes by identifying high-performing (low-mortality) centers and engaging in collaborative learning.


Assuntos
Cardiopatias/mortalidade , Mortalidade Hospitalar , Unidades de Terapia Intensiva Pediátrica/estatística & dados numéricos , Qualidade da Assistência à Saúde/estatística & dados numéricos , Fatores Etários , Pré-Escolar , Comorbidade , Grupos Diagnósticos Relacionados , Oxigenação por Membrana Extracorpórea , Feminino , Cardiopatias/epidemiologia , Humanos , Lactente , Recém-Nascido , Modelos Logísticos , Masculino , Reflexo Pupilar , Respiração Artificial/estatística & dados numéricos , Fatores de Risco , Magreza/epidemiologia
13.
Acta Neurochir (Wien) ; 158(2): 329-34; discussion 334, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26695503

RESUMO

BACKGROUND: Intraneural hemangiomas and vascular malformations are rare, with approximately 50 cases reported in the literature. They present a therapeutic challenge; surgical resection can result in damage to the nerve and lesion recurrence is common. We introduce a new framework to classify intraneural vascular anomalies in relation to the anatomic compartments of the nerve and assess amenability to surgical resection. METHODS: We retrospectively reviewed cases of intraneural hemangiomas and vascular malformations treated at our institution between 2003 and 2013 that had high-resolution 3-T magnetic resonance imaging (MRI). A review of the literature was also performed. Our cases and reports in the literature with available MRI data were sub-categorized according to their relationship to the paraneurium and epineurium of the nerve. RESULTS: Nine patients were identified with intraneural (subparaneurial or subepineurial) vascular lesions. Two patients had a predominantly subparaneurial involvement of the nerve, six patients had predominantly subepineurial involvement, and one patient exhibited extensive involvement in both compartments. Four patients were managed surgically and the rest conservatively. Targeted resection of two subparaneurial hemangiomas provided complete relief of symptoms and freedom from recurrence at 18 month and 24 months respectively. One patient with extensive subepineurial and extraneural vascular malformations did not appear to benefit from sub-total resection with interfascicular dissection. No surgical morbidity was noted in any of the cases. CONCLUSIONS: We believe that the subparaneurial compartment-a potential space between the epineurium and paraneurium-provides a tissue plane within which benign vascular lesions can occur. Hemangiomas and vascular malformations are complex and can occupy different intraneural and extraneural compartments. The anatomic framework aids surgical decision-making and ensures that all components of the lesion are considered. We advocate a multimodal approach in the treatment of these rare lesions.


Assuntos
Hemangioma/diagnóstico , Imageamento por Ressonância Magnética , Neoplasias do Sistema Nervoso Periférico/diagnóstico , Feminino , Hemangioma/diagnóstico por imagem , Hemangioma/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias do Sistema Nervoso Periférico/diagnóstico por imagem , Neoplasias do Sistema Nervoso Periférico/cirurgia , Radiografia , Adulto Jovem
14.
Cultur Divers Ethnic Minor Psychol ; 21(3): 358-68, 2015 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-25313430

RESUMO

This study investigated the effects of ingroup contact in a large, national sample of Maori (a disadvantaged ethnic group; N = 940) on political attitudes relevant to decreasing ethnic inequality in New Zealand. We tested the role of 2 mediating mechanisms-ethnic identification and system justification-to explain the effects of ingroup contact on the dependent variables. Time spent with ingroup friends predicted increased support for the Maori Party and support for symbolic and resource-specific reparative policies benefiting Maori. These effects were partially mediated by increased ethnic identification. Although ingroup contact also reduced levels of system justification among Maori, its effects on policy attitudes and party preference were not mediated by system justification. This suggests that a key antecedent to system challenging political attitudes is an increased sense of identification with a disadvantaged group resulting, in part, from interactions with ingroup friends.


Assuntos
Amigos/psicologia , Política , Identificação Social , Populações Vulneráveis/psicologia , Adulto , Atitude , Etnicidade/psicologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Nova Zelândia , Fatores Socioeconômicos
15.
Br J Soc Psychol ; 54(2): 324-40, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-25156504

RESUMO

The status-legitimacy hypothesis, which predicts that low-status groups will legitimize inequality more than high-status groups, has received inconsistent empirical support. To resolve this inconsistency, we hypothesized that low-status groups would display enhanced legitimation only when evaluating the fairness of the specific hierarchy responsible for their disadvantage. In a New Zealand-based probability sample (N = 6,162), we found that low-status ethnic groups (Asians and Pacific Islanders) perceived ethnic-group relations to be fairer than the high-status group (Europeans). However, these groups did not justify the overall political system more than the high-status group. In fact, Maori showed the least support for the political system. These findings clarify when the controversial status-legitimacy effects predicted by System Justification Theory will - and will not - emerge.


Assuntos
Havaiano Nativo ou Outro Ilhéu do Pacífico , Política , População Branca , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Nova Zelândia , Fatores Socioeconômicos
16.
Pers Soc Psychol Bull ; 39(11): 1391-403, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-23963970

RESUMO

Contact with the dominant group can increase opposition, among the disadvantaged, to social policies that would benefit their group. This effect can be explained in terms of contact promoting support for an ideology of meritocracy, which privileges the distribution of societal resources based on individual merit, rather than group-level disadvantage. We tested this ideological mechanism in a large, nationally representative sample of Maori (a disadvantaged group in New Zealand; N = 1,008). Positive intergroup contact with the dominant group (New Zealand Europeans) predicted increased opposition to a topical reparative policy (Maori ownership of the foreshore), and this was fully mediated by increased support for the ideology of meritocracy. Intergroup contact may enable the ideological legitimation of inequality among members of disadvantaged groups, engendering political attitudes that are detrimental to their group's interests. Contact with ingroup members had the opposite effect, increasing support for reparative policy by reducing subscription to meritocratic ideology.


Assuntos
Hierarquia Social , Relações Interpessoais , Fatores Socioeconômicos , Populações Vulneráveis/psicologia , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Nova Zelândia , Populações Vulneráveis/etnologia
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