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1.
J Pharm Bioallied Sci ; 16(Suppl 1): S368-S371, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38595576

RESUMO

Objective: This study sought to determine the relationship between right ventricular (RV) function and clinical variables and prognosis in individuals with acute myocardial infarction (AMI) utilizing strain imaging. Materials and Methods: A prospective observational research involving 150 patients who had been admitted with AMI was carried out. Utilizing two-dimensional speckle-tracking strain imaging, RV function was assessed. Age, sex, risk factors, and comorbidities were recorded as clinical parameters. A 12-month follow-up was conducted to assess major adverse cardiovascular events (MACE). Results: 65% of the study's participants were men, with a mean age of 58.2 years. When compared to a healthy control group, individuals with AMI had significantly lower RV longitudinal strain (RVLS) (P 0.001). RVLS and left ventricular ejection fraction had a statistically significant connection (r = 0.642, P 0.001). Patients with compromised RVLS had a greater rate of MACE over the follow-up period compared to those with maintained RV function (P = 0.014). Conclusion: In conclusion, strain imaging offers useful information for evaluating RV function in patients with AMI. Reduced left ventricular performance and a higher likelihood of unfavorable clinical outcomes are linked to impaired RVLS. Utilizing strain imaging to detect RV dysfunction early can help direct treatment plans and enhance patient outcomes.

2.
Ann Card Anaesth ; 25(3): 264-269, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35799552

RESUMO

Background: The objectives of this study were to find out of normal reference value for age-dependent longitudinal strain values in children and find its correlation with conventional echocardiographic parameters. Methods: In total, 100 healthy normal children aged between 2 and 15 years were enrolled and divided into three age groups, namely, 2-5 years, 5-10 years, and 10-15 years. Using the GE Vivid 7 ultrasound platform with 4 or 7 MHz probes, both LV and RV global longitudinal strains and conventional echocardiographic parameters were acquired. Results: In normal healthy children, left ventricular GLS values were -20.10 to -19.68 (mean: -19.89), -21.93 to -21.02 (mean: -21.48), and -20.87 to -20.41 (mean: -20.64)) in children aged 2-5 years, 5-10 years, and 10-15 years and right ventricular GLS values were -16.80 to -16.44 (mean: -16.62), -27.85 to -27.27 (mean: -27.56), -28.44 to -27.93 (mean: -28.19) in the above three groups, respectively. No significant increase was noted in the left ventricular strain value from basal to the apical segment from age group 2 years to 15 years and no gender differences were seen. None of the conventional echocardiographic parameters commonly used to assess the left or right ventricular systolic function had a significant correlation with LVGLS and RVGLS. Conclusions: The mean LVGLS values were -19.89, -21.48, and -20.64 and RVGLS were -16.62, -27.56, and -28.19 in healthy normal children aged 2-5 years, 5-10 years, and 10-15 years, respectively, and conventional echocardiographic parameters did not have any significant correlation with these values.


Assuntos
Ecocardiografia , Função Ventricular Esquerda , Função Ventricular Direita , Adolescente , Criança , Pré-Escolar , Ecocardiografia/métodos , Feminino , Ventrículos do Coração/diagnóstico por imagem , Humanos , Masculino , Fatores Sexuais , Sístole
3.
J Comput High Educ ; 34(3): 844-867, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35668837

RESUMO

The concept of e-learning has now become fundamental in student learning process. This concept becomes even more relevant in situations of global crisis such as that arising from COVID-19. Since this pandemic there have been tectonic shifts in the education sector. Effective implementation of e-learning in higher education depends on students' adoption of this technology. So, this study aimed to identify the factors influencing the behavioral intentions and actual usage of students in adopting e-learning. Additionally, it also examined the mediation effects among different latent constructs. Based on technology acceptance model (TAM), an explanatory structural model of technology acceptance was tested along with introduction of three external variables. To do this, a quantitative investigation was conducted using an online survey of higher education students in India, obtaining 570 responses. The structural model was examined through the partial least square structural equation modeling. Results obtained make it possible to validate the proposed model as findings explains the 56.2% variance of actual usage. In addition, it shows the direct and indirect effect of all three selected external variables of personal innovativeness, social factors and self-efficacy on the main constructs of TAM. The findings of this study are relevant for the higher education management, administration, e-learning system developers, marketers and researchers for improving the effective usage of e-learning by developing more focused and customized learning solutions.

4.
Environ Sci Pollut Res Int ; 26(22): 23173-23191, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31190302

RESUMO

It is evident from the past studies that dust fallout is a severe concern due to its impact to urban air quality and public health. This study mainly examines the spatial and seasonal variation of dustfall at ambient levels and chemical characterization of its insoluble fraction for Kharagpur Town, India. Dustfall samples were collected monthly for 1 year (July 2014 to June 2015) from four sampling sites. The results showed that the maximum dustfall deposition is found during summer (March to June) and in the range of 2.01 ± 0.36 to 15.74 ± 3.83 ton km-2 month-1, and minimum deposition is during monsoon season (July to October) in the range of 0.42 ± 0.72 to 7.38 ± 5.8 ton km-2 month-1. Selected metals like Sc, V, Cr, Co, Ni, Zn, Y, Zr, Ce, Hf, and Pb were analyzed using the high-resolution inductively coupled mass spectrometer (HR-ICP-MS) technique, and the contamination level of heavy metals was assessed using the geoaccumulation index (Igeo) and enrichment factor (EF). To estimate the sources for the metallic contaminants, principal component analysis (PCA) was conducted. The US EPA health risk assessment model was applied to determine the hazard index and hazard quotient values. The results show the significant level of enrichment for Pb (EF = 41.79) and Cr (EF = 4.39). The Igeo values point out moderate contamination by Pb (Igeo = 2.01) and Cr (Igeo = 1.6) in Kharagpur Town. This study suggests that in the context of noncancer risk of heavy metals as determined by the hazard index (HI) and hazard quotient (HQ) values, ingestion is the main source of exposure to dust in adults and children followed by dermal contact. Considering the inhalation route, carcinogenic risk level of Cr, Co, and Ni for adults and children is lower than the EPA's safe limit (10-6 to 10-4), indicating that cancer risk of these metals due to exposure to dustfall in Kharagpur is negligible.


Assuntos
Poeira/análise , Metais Pesados/análise , Adulto , Poluição do Ar/análise , Criança , Cidades , Humanos , Índia , Metais Pesados/química , Medição de Risco , Estações do Ano , Estados Unidos , United States Environmental Protection Agency/legislação & jurisprudência
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