RESUMO
In this manuscript, we present the first experience of evaluating donation after circulatory death (DCD) lungs, using the normothermic preservation Organ Care System (OCS) and subsequent successful transplantation. The OCS could be a useful tool for the evaluation of marginal lungs from DCD donors as it allows a proper recruitment and bronchoscopy in such donations in addition to continuous ex-vivo perfusion and assessment and treatment during transport. The OCS could potentially be a standard of care in the evaluation of marginal lungs from DCD.
Assuntos
Transplante de Pulmão , Pulmão , Obtenção de Tecidos e Órgãos , Transplantes , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
Two cases of laboratory-confirmed listeriosis were detected in Bizkaia, Spain, at the end of August. The epidemiological investigation indicated that these two cases were associated with the consumption of Latin-style fresh cheese made from pasteurised milk in Portugal. Different batches of the same cheese were analysed and confirmed as contaminated with Listeria monocytogenes. The product was withdrawn from the market and the population was advised not to consume this kind of cheese.
Assuntos
Queijo/microbiologia , Surtos de Doenças , Microbiologia de Alimentos , Listeria monocytogenes/isolamento & purificação , Listeriose , Adulto , Sangue/microbiologia , Queijo/análise , Queijo/economia , Busca de Comunicante , Métodos Epidemiológicos , Comportamento Alimentar/psicologia , Feminino , Microbiologia de Alimentos/normas , Serviços de Alimentação/normas , Serviços de Alimentação/estatística & dados numéricos , Humanos , Recém-Nascido , Período de Incubação de Doenças Infecciosas , Listeria monocytogenes/genética , Listeria monocytogenes/patogenicidade , Listeriose/epidemiologia , Listeriose/transmissão , Troca Materno-Fetal , Placenta/microbiologia , Gravidez , Fatores de Risco , Sepse/epidemiologia , Espanha , Inquéritos e QuestionáriosRESUMO
OBJECTIVES: The aim of the present study was to evaluate DNA damage (micronucleus) and cellular death (pyknosis, karyolysis and karyorrhexis) in exfoliated buccal mucosa cells from individuals following radiography. METHODS: Lateral and frontal cephalometric X-ray and panoramic dental X-rays were taken of a total of 18 healthy patients (6 male and 12 female) referred for orthodontic therapy. Exfoliated oral mucosa cells were collected immediately before X-ray exposure and after 10 days. RESULTS: The results revealed no statistically significant difference (P > 0.05) in the frequency micronucleated oral mucosa cells after X-ray exposure. However, X-ray was able to increase other nuclear alterations closely related to cytotoxicity, such as karyorrhexis, pyknosis and karyolysis. CONCLUSIONS: Data indicated that exposure to certain radiography may not be a factor in inducing chromosomal damage, but it does promote cytotoxicity.