[Economic burden and related factors on inpatients with HBV-related diseases in Shandong province].

OBJECTIVE: To investigate the economic burden of patients with acute and chronic hepatitis B, cirrhosis and liver cancer caused by hepatitis B virus (HBV). METHODS: Cluster sampling was used on cases consecutively collected during the study period. Questionnaire survey was conducted and information on the expenses during hospitalization was collected from the hospital records and through interviewing those patients. RESULTS: Yearly costs related to patients with acute hepatitis B, severe hepatitis B, chronic hepatitis B, cirrhosis, hepatocellular carcinoma were 66.7, 138.1, 127.4, 151.7 and 377.2 thousand Yuan, respectively. RESULTS: from multiple linear regression model showed that the type of medical insurance scheme, annual days of hospitalization, classifications of HBV-related diseases and personal income were major influencing factors on the cost. CONCLUSION: HBV infection caused considerable burden to families and the society, indicating that HBV infection control programs would bring huge potential benefits. The reform of insurance scheme should be administrated to promote social fairness.

[The investigation on economic burden with outpatient of varicella in Shandong, Gansu and Hunan provinces in 2007].

OBJECTIVE: To analyse the economic burden of outpatient with varicella in China in 2007. METHODS: In three provinces, the sample were places are stratified by economic condition in district, county and township level. 811 outpatient cases were sampled and analysized. RESULTS: The cost of outpatient was 493.66 RMB per case, including direct expenses 219.52 RMB and indirect expenses 274.14 RMB per case. The total cost of outpatient varicella in China was 2.3 billion RMB in 2007. CONCLUSIONS: The disease burden was heavy in China.

[Economic burden of inpatient of varicella in Shandong, Gansu and Hunan provinces, 2007].

OBJECTIVE: To analysis the economic burden of varicella inpatient in China, 2007. METHODS: In three provinces, the sample places stratified by economic status in district, county and township level and were selected. 185 varicella inpatients were sampled and analysized. RESULTS: The cost of inpatient was 4025.86 RMB per case, including RMB 2952.6 direct cost and RMB 1073.26 indirect cost per case. The total cost of varicella inpatient in China was RMB 103 million in 2007. CONCLUSION: The disease burden is heavy in China.

[Analysis on coverage of hepatitis A vaccine among pre-school children in Shandong province].

OBJECTIVE: To reveal the hepatitis A vaccine (HepA) coverage among pre-school children in Shandong province before Hepatitis A vaccine was introduced to the EPI and to provide evidence for improving the strategy for hepatitis A control. METHODS: A cross-section survey was conducted among children aged between 2 and 6 years old in Shandong province in March 2008. The study population was selected by random sampling method and HepA immunization history was obtained by immunization record or recall. RESULTS: 78.90% had received one dose of HepA at least. The coverage rate decreased with age and the differences in three age groups were statistically significant (chi2 = 11.54, P = 0.02). The coverage rates among the boys and girls were 77.67% and 80.30% respectively, the difference was not significantly (chi2 = 1.17, P = 0.28). The HepA coverage rates among the children living in the eastern areas and in the richer areas were higher than the centrale and western areas and poverty areas, the difference has statistic significance (chi2 = 27.25, 58.17, P < 0.001). CONCLUSION: The HepA routine immunization should be enhanced, especially in central and western areas and a HepA catch-up campaign should be conducted among the pre-school children in Shandong province.