RESUMO
Analyses of healthcare databases (claims, electronic health records [EHRs]) are useful supplements to clinical trials for generating evidence on the effectiveness, harm, use, and value of medical products in routine care. A constant stream of data from the routine operation of modern healthcare systems, which can be analyzed in rapid cycles, enables incremental evidence development to support accelerated and appropriate access to innovative medicines. Evidentiary needs by regulators, Health Technology Assessment, payers, clinicians, and patients after marketing authorization comprise (1) monitoring of medication performance in routine care, including the materialized effectiveness, harm, and value; (2) identifying new patient strata with added value or unacceptable harms; and (3) monitoring targeted utilization. Adaptive biomedical innovation (ABI) with rapid cycle database analytics is successfully enabled if evidence is meaningful, valid, expedited, and transparent. These principles will bring rigor and credibility to current efforts to increase research efficiency while upholding evidentiary standards required for effective decision-making in healthcare.
Assuntos
Pesquisa Biomédica/organização & administração , Bases de Dados Factuais/estatística & dados numéricos , Tomada de Decisões , Atenção à Saúde/organização & administração , Eficiência Organizacional , Atenção à Saúde/normas , Difusão de Inovações , Registros Eletrônicos de Saúde , Acessibilidade aos Serviços de Saúde , Humanos , Avaliação da Tecnologia BiomédicaRESUMO
1. The immediate needs of spine-injured patients, families and friends is for answers, advice, support and counselling. 2. Newly injured patents and their families and friends need continuous support and information throughout long-term rehabilitation. 3. Consideration must be given to the injured patient as a whole person because physical and psychological rehabilitation are dependent on each other.
Assuntos
Traumatismos da Coluna Vertebral/psicologia , Aconselhamento , Família , Feminino , Necessidades e Demandas de Serviços de Saúde , Humanos , Pessoa de Meia-Idade , Traumatismos da Coluna Vertebral/reabilitaçãoRESUMO
Examines the present strengths and weaknesses of the general practice system. Proposes a different structure for the future which should provide benefits for both the purchasers and providers of health care, as well as for the patients themselves.