[Growth assessment in children with intrauterine growth retardation (IUGR) - preliminary results]. / Ocena wzrastania dzieci z wewnatrzmacicznym opóznieniem wzrastania (IUGR) w materiale wlasnym - doniesienie wstepne.

In 28 children aged 2.3-12 years born with birth weight less than -2 SD for gestational age we assessed growth according to birth weight and height, duration of gestation, mid- parental height, and somatotropic axis. All children were subjected to auxological evaluation every 3 months. The assessment included changes of height for chronological age standard deviation score (DeltaH SDS CA), height for bone age (DeltaH SDS BA), growth velocity (GV SDS) and height - mid-parental height (H SDS-MPH SDS). We observed a significant growth improvement in children with lower birth weight (r=-0.5, p<0.0059), a positive correlation between IGF-1 level and catch -up growth (DeltaH SDS CA) (r=0.5, p<0.048) and maximum GH level (stimulation test) and growth velocity (GV SDS) (r=0.8, p<0.01). These data suggest that children with lower IGF-1 and GH levels, as well as birth weight within -2 SDS could be treated with growth hormone. However, this theory requires further evaluation.

[Effect of hemodialysis on left ventricular function in patients with chronic renal failure assessment with radionuclide ventriculography]. / Wplyw hemodializy na czynnosc lewej komory u chorych z przewlekla niewydolnoscia nerek. Ocena wentrykulografia izotopowa.

To examine the effects of haemodialysis (HD) on left ventricular (LV) function, gated radionuclide ventriculography was conducted before and after HD in 16 patients with chronic renal failure (CRF) and in 12 healthy persons. The LV sectorial function was assessed by subdividing the LV region of interest into 6 sectors. Global ejection fraction (EF) was unchanged by dialysis (61.4 +/- 8.3% before vs. 63.5 +/- 10.4% after) (mean +/- S.D.). EF of sectors 4 and 5 was improved significantly (69.3 +/- 10.7% and 85.6 +/- 17.1% before vs. 81.7 +/- 18.4% and 97.4 +/- 22.0% after) (p < 0.05 and p < 0.05). The peak ejection rate (PER) was increased following HD (3.07 +/- 1.03 EDc/s before vs. 3.88 +/- 0.88 EDc/s after) (p < 0.02). The time to end systole (TES) corrected for R-R interval was unchanged by HD (46.3 +/- 6.3 before vs. 43.8 +/- 5.3 after). The peak filling rate (PFR) was unchanged by HD (3.41 +/- 0.77 EDc/s before vs. 3.05 +/- 0.45 EDc/s after). The time to peak filling rate (TPFR) corrected for R-R interval was increased (21.8 +/- 5.3 before vs 25.9 +/- 5.0 after) (p < 0.02). This study indicates that HD produces beneficial effects on LV systolic function in CRF patients and does not improve LV filling in early diastole.