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1.
Phys Med Biol ; 56(17): 5525-34, 2011 Sep 07.
Artigo em Inglês | MEDLINE | ID: mdl-21813962

RESUMO

We aimed to estimate the scattered radiation from dental metallic crowns during head and neck radiotherapy by irradiating a jaw phantom with external photon beams. The phantom was composed of a dental metallic plate and hydroxyapatite embedded in polymethyl methacrylate. We used radiochromic film measurement and Monte Carlo simulation to calculate the radiation dose and dose distribution inside the phantom. To estimate dose variations in scattered radiation under different clinical situations, we altered the incident energy, field size, plate thickness, plate depth and plate material. The simulation results indicated that the dose at the incident side of the metallic dental plate was approximately 140% of that without the plate. The differences between dose distributions calculated with the radiation treatment-planning system (TPS) algorithms and the data simulation, except around the dental metallic plate, were 3% for a 4 MV photon beam. Therefore, we should carefully consider the dose distribution around dental metallic crowns determined by a TPS.


Assuntos
Carcinoma de Células Escamosas/radioterapia , Coroas , Neoplasias de Cabeça e Pescoço/radioterapia , Metais/química , Método de Monte Carlo , Planejamento da Radioterapia Assistida por Computador/métodos , Espalhamento de Radiação , Algoritmos , Carcinoma de Células Escamosas/diagnóstico por imagem , Simulação por Computador , Neoplasias de Cabeça e Pescoço/diagnóstico por imagem , Humanos , Imagens de Fantasmas , Fótons/uso terapêutico , Doses de Radiação , Radiografia , Radiometria/métodos , Radioterapia de Alta Energia/efeitos adversos , Sensibilidade e Especificidade , Carcinoma de Células Escamosas de Cabeça e Pescoço
2.
Phys Med Biol ; 54(11): 3491-500, 2009 Jun 07.
Artigo em Inglês | MEDLINE | ID: mdl-19436105

RESUMO

Intraoperative electron beam radiotherapy (IOERT) is a technique in which a single-fraction high dose is intraoperatively delivered to subclinical tumour cells using an electron beam after breast-conserving surgery. In IOERT, an attenuation plate consisting of a pair of metal disks is commonly used to protect the normal tissues posterior to the breast. However, the dose in front of the plate is affected by backscatter, resulting in an unpredictable delivered dose to the tumour cells. In this study, an experimental attenuation plate, termed a shielding plate, was designed using Monte Carlo simulation, which significantly diminished the electron beam without introducing any backscatter radiation. The plate's performance was verified by measurements. It was made of two layers, a first layer (source side) of polymethyl methacrylate (PMMA) and a second layer of copper, which was selected from among other metals (aluminium, copper and lead) after testing for shielding capability and the range and magnitude of backscatter. The optimal thicknesses of the PMMA (0.71 cm) and copper (0.3 cm) layers were determined by changing their thicknesses during simulations. On the basis of these results, a shielding plate was prototyped and depth doses with and without the plate were measured by radiophotoluminescence glass dosimeters using a conventional stationary linear accelerator and a mobile linear accelerator dedicated for IOERT. The trial shielding plate functioned as intended, indicating its applicability in clinical practice.


Assuntos
Neoplasias da Mama/radioterapia , Neoplasias da Mama/cirurgia , Elétrons , Planejamento da Radioterapia Assistida por Computador/métodos , Terapia Combinada , Simulação por Computador , Cobre/química , Feminino , Humanos , Método de Monte Carlo , Aceleradores de Partículas , Polimetil Metacrilato/química , Radioterapia/instrumentação , Dosagem Radioterapêutica , Análise Espectral
3.
Phys Med Biol ; 52(2): 515-23, 2007 Jan 21.
Artigo em Inglês | MEDLINE | ID: mdl-17202630

RESUMO

To calculate photon spectra for a 10 MV x-ray beam emitted by a medical linear accelerator, we performed numerical analysis using the aluminium transmission data obtained along the central axis of the beam under the narrow beam condition corresponding to a 3x3 cm2 field at a 100 cm distance from the source. We used the BFGS quasi-Newton method based on a general nonlinear optimization technique for the numerical analysis. The attenuation coefficients, aluminium thicknesses and measured transmission data are necessary inputs for the numerical analysis. The calculated x-ray spectrum shape was smooth in the lower to higher energy regions without any angular components. The x-ray spectrum acquired by the employed method was evaluated by comparing the measurements along the central axis percentage depth dose in a water phantom and by a Monte Carlo simulation code, the electron gamma shower code. The values of the calculated percentage depth doses for a 10x10 cm2 field at a 100 cm source-to-surface distance in a water phantom were obtained using the same geometry settings as those of the water phantom measurement. The differences in the measured and calculated values were less than +/-1.0% for a broad region from the shallow part near the surface to deep parts of up to 25 cm in the water phantom.


Assuntos
Aceleradores de Partículas , Planejamento da Radioterapia Assistida por Computador/métodos , Raios X , Alumínio/química , Humanos , Modelos Estatísticos , Modelos Teóricos , Método de Monte Carlo , Imagens de Fantasmas , Fótons , Radiometria , Dosagem Radioterapêutica , Água/química
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