Burden of Lung Cancer in China, 1990-2019: Findings from the Global Burden of Disease Study 2019.

BACKGROUND: Lung cancer is one of the most common malignant tumors in the world. It has become an increasingly important public health problem in China. In this study, we systematically assessed the lung cancer situation in China from 1990 to 2019 and provided an epidemiological knowledge base for the revision of health policies. The relevant data were extracted from the Global Burden of Disease (GBD) database. METHODS: Based on GBD 2019 data, we evaluated the incidence, prevalence, and death rates of lung cancer in China and their change trends from 1990 to 2019, making comparisons by gender and age. RESULTS: The age-standardized incidence and death rates (ASIR and ASDR, respectively) of lung cancer in China were higher than the average levels in Asia, Africa, Europe, and Oceania and also higher than those of neighboring Asian countries. Lung cancer rose from the seventh leading cause of death in 1990 to the fourth leading one in 2019, indicating that the disease burden of lung cancer is increasing. In 2019, the incidence, prevalence, and death rates of lung cancer were all higher in men than in women across all age groups. All three indices were lower in men and women <50 years old than in men and women >50 years. From 1990 to 2019, the ASIR, age-standardized prevalence rate (ASPR), and ASDR showed trends of increase (P < .05), and the rise in the ASPR (average annual percentage change [AAPC] = 1.9) was greater than those in the ASIR (AAPC = 1) and ASDR (AAPC = .8). CONCLUSIONS: From 1990 to 2019, the incidence, prevalence, and death rates of lung cancer continued to increase in China. To reduce this burden, prevention and management of known risk factors should be promoted through national policies.

Changes of cropland evapotranspiration and its driving factors on the loess plateau of China.

Agricultural water resource, mainly consumed through evapotranspiration, plays a critical role in agricultural production of arid and semiarid regions. Quantifying the changes of evapotranspiration in cropland (ETc), and its driving factors, may provide rich information for improving human land-use and water resource management. Here we first investigated the multi-year (2000-2015) changes in the ETc (mm yr-1) and associated driving factors of the Loess Plateau (LP), using a combination of the Vegetation Interfaces Processes model and a factorial analysis of variance. We found that the ETc of the LP showed a significant upward trend of 0.31 km3 yr-2 (3.33 mm yr-2) (p < .05) over the last 16 years, mainly driven by cropland changes (3.77% per year), which combined the contribution of cropland area changes and cropland leaf area index (LAIc) changes. We then examined the changes of the dominant driving factor: cropland, and results indicated that the cropland changes consisted of the decrease in cropland area (net decrease of 10.50 × 103 km2) and the increase in LAIc (increased by 10.72%), which suggest the actual contribution of the ETc uptrend was the increasing LAIc. Our further analysis on the causes of the increasing LAIc by correlating the LAIc with land-use management factors revealed that the cropland greening on the LP showed high positive correlations with the increasing inputs of total power of agriculture machinery and farm plastic film, followed by chemical fertilizer. The increase of LAIc was also promoted by the increased ratio of the garden fruits output to total crops output (increased by 67.12%) and multiple cropping (increased by 21.66%). These results suggest that the ETc uptrend can be related to the agricultural intensification. Our study highlights the need for a realistic representation of socio-economic development and human land-use practices in the sustainable optimal allocation of agricultural water resources on the LP.