Influence of industrial sustainability transition on air quality in a typical resource-exhausted city.

The industrial transition of resource-exhausted cities is the focus of attention, and air quality has naturally become an important indicator to measure the sustainable development quality. Aerosol optical depth (AOD) is an important parameter to indicate air quality. This paper aimed to study the influence of industrial transition on air quality and provide a list of recommendations and management strategies for sustainable development in resource-exhausted cities. Results showed the secondary industry played important roles for economic development before 2015, however, it decreased after 2014, and the tertiary industry played more and more important roles from 2015. Analyses of the spatial distribution of AOD in each year showed that AOD was relatively higher in urban areas with concentrated population, and the threshold range of AOD value with high area ratio in spatial distribution decreased gradually, which was consistent with the analysis results of time series. Results of correlation analyses indicated that air temperature and land surface temperature were the main natural meteorological factors influencing AOD. Gross population, SO2 emission and the cultivated land area were the main socio-economic factors influencing AOD. It could be concluded that the industrial transition of the city has achieved good results, the economic structure has been gradually optimized and adjusted, and the air quality has gradually improved over industrial sustainability transition. Scientific exploitation, energy conservation, application of clean energy and industrial structure optimization would be effective measures for sustainable development.

Assessment of the Diagnostic Performance of Clinical Examinations and High-Frequency Ultrasound in Patients With Pigmented Skin Tumors.

OBJECTIVES: To investigate whether the integration of high-frequency ultrasound (HFUS) to routine clinical examinations could improve diagnostic performance and management decision for pigmented skin tumors. METHODS: Three general practitioners trained previously and a dermatologist independently assessed pigmented skin tumors and rendered management decision based on clinical examinations alone or clinical examinations integrating HFUS. RESULTS: After integrating HFUS, the diagnostic area under the curve (AUC) (0.658-0.693 versus 0.848, all P < .05) and specificity (46.6-58.6% versus 89.7%, all P < .05) for pigmented skin malignancies were improved for general practitioners, meanwhile unnecessary biopsy rate reduced (42.9-53.6% versus 10.7%, P < .001). To the dermatologist, the diagnostic AUC (0.822 versus 0.949, P < .001), sensitivity (81.7% versus 96.7%, P = .012) and specificity (0.828 versus 0.931, P = .031) improved significantly, meanwhile both missed biopsy rate (14.5% versus 4.8%, P = .031) and unnecessary biopsy rate (19.6% versus 7.1%, P = .016) decreased. Additionally, the diagnostic performance of the general practitioner with integrating HFUS could be comparable with the dermatologist based on clinical examinations alone (all P > .05). CONCLUSIONS: As a complementary tool of clinical examinations, HFUS could help physicians differentiate pigmented skin malignancies and manage decision.

OCT angiography in the monitoring of vaginal health.

Fractional-pixel CO2 laser therapy shows promise for treating the genitourinary syndrome of menopause (GSM). Nevertheless, it remains controversial in the field of female pelvic medicine. This is due to the inherent difficulties in obtaining noninvasive biopsies to evaluate the treatment's efficacy and safety objectively. To address this challenge, we developed a noninvasive intravaginal optical coherence tomography (OCT)/OCT angiography (OCTA) endoscopic system, whose probe features a shape identical to the laser treatment probe. This system can provide high-resolution OCT images to identify the microstructure of vaginal tissue and visualize the vasculature network in vivo. We conducted clinical research on 25 post-menopausal patients with GSM. OCT/OCTA scans were acquired at four different locations of the vagina (distal anterior, distal posterior, proximal anterior, and proximal posterior) during the whole laser treatment session. A U-Net deep learning model was applied to segment the vaginal epithelium for assessing vaginal epithelial thickness (VET). Blood vessel density and VET were quantified to monitor the efficacy of fractional-pixel CO2 laser therapy. Statistical correlation analyses between these metrics and other clinical scores were conducted, validating the utility of our system. This OCT/OCTA endoscopic system has great potential to serve as a noninvasive biopsy tool in gynecological studies to screen, evaluate, and guide laser treatment for GSM.

Impact of long-term care insurance on the health status of middle-aged and older adults.

With the increase of aging population, long-term care insurance (LTCI) systems have become important for improving individuals' health. However, the effect of LTCI on health is unclear, especially in developing countries, owing to the lack of random policy shocks and comprehensive databases. This study investigates the Chinese LTCI pilot program, using four waves of the China Health and Retirement Longitudinal Study database (sample aged ≥45 years) from 2011 to 2018. The recent difference-in-differences approaches for staggered design, which are capable of dealing with the negative weights issue, are used to investigate changes in health status, measured by self-rated health (SRH), (instrumental) activities of daily living, self-rated depression, and cognition, in pilot and non-pilot cities before and after LTCI implementation. Long-term care insurance has a significant average effect on SRH improvement and a long-term positive effect on cognition for middle-aged and older populations. This study provides the first evaluation of LTCI policy on health outcomes using the recent difference-in-differences approaches. It provides evidence for the overall health improvement achieved through the LTCI and offers positive reinforcement and potential areas for improvement in establishing LTCI worldwide.

Waste-to-Resource Strategy to Fabricate Functionalized MOFs Composite Material Based on Durian Shell Biomass Carbon Fiber and Fe3O4 for Highly Efficient and Recyclable Dye Adsorption.

Recently, metal-organic frameworks (MOFs), which are porous inorganic-organic hybrid materials consisting of metal ions (clusters or secondary building units) and organic ligands through coordination bonds, have attracted wide attention because of their high surface area, huge ordered porosity, uniform structural cavities, and excellent thermal/chemical stability. In this work, durian shell biomass carbon fiber and Fe3O4 functionalized metal-organic framework composite material (durian shell fiber-Fe3O4-MOF, DFM) was synthesized and employed for the adsorption removal of methylene blue (MB) from wastewater. The morphology, structure, and chemical elements of the DFM material were characterized by scanning electron microscope (SEM), X-ray diffraction (XRD), transmission electron microscope (TEM), and X-ray photoelectron spectroscope (XPS) techniques. Adsorption conditions such as pH, adsorption time, and temperature were optimized. The adsorption isotherm and kinetics results show that the adsorption process of DFM material to MB is more in line with the Freundlich model and pseudo-second-order kinetic model. Using these models, the maximum adsorption capacity of 53.31 mg/g was obtained by calculation. In addition, DFM material could be easily reused through an external magnet and the removal rate of MB was still 80% after five adsorption cycles. The obtained results show that DFM composite material, as an economical, environmentally friendly, recyclable new adsorbent, can simply and effectively remove MB from wastewater.

Assessment of Eyelid Pressure Using a Novel Pressure Measurement Device in Patients With Moderate-to-Severe Dry Eye Disease.

OBJECTIVE: To assess a novel eyelid pressure measurement device and study the relationship between eyelid pressure and ocular surface parameters of moderate-to-severe dry eye disease (DED). METHODS: The present study included 70 eyes of 35 moderate-to-severe DED patients. All subjects were subjected to the following examinations for DED assessment: Ocular Surface Disease Index (OSDI) questionnaire, tear meniscus height (TMH), lipid layer thickness (LLT), number of partial blink (PB), total blink (TB) and partial blink rate (PBR), fluorescein tear breakup time (FBUT), corneal fluorescein staining (CFS), lid margin abnormality, meibum expression assessment (meibum score), meibomian gland dropout (MGd) and Schirmer I test. Pressure of the upper eyelid was measured thrice with the novel pressure measurement device. Repeatability of the device was evaluated by intraclass correlation coefficient (ICC). Safety of the device was evaluated by observing ocular adverse reactions of each subject prior to measurement, at day 1 and day 7 following measurement. Correlations between eyelid pressure and ocular surface parameters of moderate-to-severe DED were analyzed by using Pearson correlation coefficient and Kendall's tau-b correlation coefficient. RESULTS: ICC of the measurement results in our study was 0.86. There was no abnormality presenting in all subjects recorded prior to measurement, 1 and 7 days following measurement. The eyelid pressure was significantly correlated with PBR (r = 0.286, P = 0.016), FBUT (r = -0.331, P = 0.005), CFS (r = 0.528, P = 0.000), lid margin abnormality (r = 0.408, P = 0.011) and MGd (r = 0.226, P = 0.016) in moderate-to-severe DED patients, but not significantly correlated with OSDI score (r = 0.016, P = 0.912), TMH (r = -0.002, P = 0.988), meibum score (r = -0.196, P = 0.317), LLT (r = 0.114, P = 0.346), PB (r = 0.116, P = 0.338), TB (r = 0.074, P = 0.544), meibum score (r = -0.196, P = 0.317) and Schirmer I test (r = 0.028, P = 0.821). CONCLUSION: The novel pressure measurement device exhibited good repeatability and safety in measuring eyelid pressure. Significant correlations were noted between the eyelid pressure and PBR, FBUT, CFS, lid margin abnormality and MGd in moderate-to-severe DED. The measurement of eyelid pressure combined with ocular surface parameters may be valuable for the assessment of DED.

The informal economy at times of COVID-19 pandemic.

We provide a first view of vulnerable informal economy after the blows from COVID-19, using transaction-level business data of around 80 million offline micro businesses (OMBs) owners from the largest Fintech company in China and employing machine learning method for causal inference. We find that the OMBs activities in China experienced an immediate and dramatic drop of 50% during the trough. The businesses had rebounded to around 80% of where they should be seven weeks after the COVID-19 outbreak, but had remained at this level until the end of our time window. We find a larger disruption to the OMBs in urban areas, the female merchants and the merchants who were not grown up in the places where they conducted businesses. We discuss the implications for policy support to the most vulnerable, and highlight the importance to take full advantage of digital development to follow up the informal economy.

Comparison of CAIPIRINHA-accelerated 3D fat-saturated-SPACE MRI with 2D MRI sequences for the assessment of shoulder pathology.

OBJECTIVES: To compare the performance of 6-min MRI with a fat-saturated 3D-controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) Sampling perfection with application-optimized contrast using different flip angle evolution (SPACE) TSE protocol with 10-min 2D TSE MRI protocol for assessment of abnormalities of the shoulder. METHODS: Forty-nine subjects underwent both 3D fat-saturated-CAIPIRINHA SPACE and 2D TSE sequences of the shoulder on a 3.0-T system. Following randomization and anonymization, two musculoskeletal radiologists evaluated the 2D and 3D images independently for image quality and diagnostic capability. Descriptive statistics, inter-observer, and inter-method concordance were investigated. p values < 0.05 were considered significant. RESULTS: For image quality assessment, 2D images were similar to 3D CAIPIRINHA SPACE images (p = 0.05). 3D had lower noise standard deviation (SD) and higher fluid CNR than 2D images (p = 0.00). For diagnostic capability assessment, using 2D TSE as a standard of reference, sensitivity, specificity, and accuracy of 3D SPACE were, respectively, 94.81%, 94.12%, and 94.39% for tendon abnormalities; 97.06%, 80.00%, and 91.84% for acromioclavicular joint abnormalities; 88.89%, 100.00%, and 93.89% for adjacent bone alterations; and 97.30%, 100%, and 97.96% for joint fluid/effusion assessment. The inter-method concordance was moderate to almost perfect. The inter-observer-concordance of the shoulder assessment was also moderate to almost perfect, with SSP lesions demonstrating the greatest concordance. CONCLUSIONS: The performance of 6-min 3D fat-saturated-CAIPIRINHA SPACE MRI for shoulder MRI is similar to that of 10-min 2D TSE MRI. 3D fat-saturated-CAIPIRINHA SPACE MRI can be utilized to reduce scan time without degradation in image quality. KEY POINTS: • CAIPIRINHA acceleration 3D fat-saturated-MRI of the shoulder is achievable in 6 min with high spatial resolution. • 3D fat-saturated CAIPIRINHA MRI is similar to 2D MRI in the shoulder assessment. • 3D CAIPIRINHA MRI images enable rapid diagnosis of shoulder abnormalities without image quality degradation.

Autonomy or Working Conditions?-Research on Heterogeneity and Influencing Mechanism of Self-Employment on Job Satisfaction in China.

The development of globalization and information technology has been promoting informal work rapidly. In this process, self-employment is gradually becoming an important employment approach. As two of the key variables, self-employment laborers' work autonomy and work conditions are largely discussed as the potential determinants of their work satisfaction. Which of these two factors is actually influencing labors' satisfaction level? So far, relevant studies are insufficient to respond to this question, especially in developing countries. This study investigates the influence of work autonomy and working conditions on self-employed workers' job satisfaction in China. China Labor-force Dynamics Survey data is used to examine the impact of self-employment on workers' job satisfaction and the influence mechanism of work autonomy and working conditions. Propensity score matching and instrumental variable methods were applied to avoid sample selection bias and endogeneity. We found that self-employment has a significant negative effect on job satisfaction; poor working conditions are responsible for self-employed workers' lower satisfaction level, and self-employment behavior impacts job satisfaction differently in terms of the type and gender of self-employed workers. Therefore, stronger social security and better working conditions for the self-employed should be provided.

Female sex is associated with a lower risk of bone metastases and favourable prognosis in non-sex-specific cancers.

BACKGROUND: The objectives were to investigate the disparity in the prevalence of bone metastases (BM) between the sexes and to assess the effect of female sex on the development and prognosis of BM. METHODS: Cases of invasive non-sex-specific cancers diagnosed between 2010 and 2015 in the Surveillance, Epidemiology, and End Results (SEER) program were used. The prevalence of BM was calculated by combining the prevalence of BM among different cancers. Multivariable logistic regression and proportion hazard regression were conducted to investigate the effect of female sex, and the results were pooled by meta-analysis. RESULTS: The pooled prevalence of BM among male and female patients was 2.3% (95% CI: 1.6-3.2%) and 1.8% (95% CI: 1.2-2.6%), respectively. The pooled prevalence of BM dramatically decreased for patients aged 11-40 years old, plateaued for patients aged 41-90 years old and increased for patients aged > 90 years old in both male and female patients. Meta-analysis suggested that female sex had a protective effect on the development of BM (pooled OR = 0.80; 95% CI: 0.75-0.84; p < .001) and a favourable prognosis for respiratory system cancers (pooled HR = 0.81; 95% CI: 0.71-0.92; p < .001). However, no significant associations existed for other cancers. Male non-sex-specific cancer patients and those with male-leaning genetic variations or hormonal status have a greater likelihood of developing BM than female patients. CONCLUSIONS: Female sex was associated with fewer BM in various non-sex-specific cancers, and the effect was constant with changes in age. Female sex showed a protective effect exclusively on the prognosis of respiratory system cancers.

Toward Cost-Effective Mobile Video Streaming through Environment-Aware Watching State Prediction.

Mobile video applications are becoming increasingly prevalent and enriching the way people learn and are entertained. However, on mobile terminals with inherently limited resources, mobile video streaming services consume too much energy and bandwidth, which is an urgent problem to solve. At present, research on cost-effective mobile video streaming typically focuses on the management of data transmission. Among such studies, some new approaches consider the user's behavior to further optimize data transmission. However, these studies have not adequately discussed the specific impact of the physical environment on user behavior. Therefore, this paper takes into account the environment-aware watching state and proposes a cost-effective mobile video streaming scheme to reduce power consumption and mobile data usage. First, the watching state is predicted by machine learning based on user behavior and the physical environment during a given time window. Second, based on the resulting prediction, a downloading algorithm is introduced based on the user equipment (UE) running mode in the LTE system and the VLC player. Finally, according to the corresponding experimental results obtained in a real-world environment, the proposed approach, compared to its benchmarks, effectively reduces the data usage (14.4% lower than that of energy-aware, on average) and power consumption (about 19% when there are screen touches) of mobile devices.

Socioeconomic Disparity in Global Burden of Cataract: An Analysis for 2013 With Time Trends Since 1990.

PURPOSE: To assess socioeconomic disparity in global burden of cataract, by using disability-adjusted life years (DALYs). DESIGN: International, comparative burden-of-disease study. METHODS: Published data on national age-standardized DALY rates caused by cataract and human development index (HDI) between 1990 and 2013 were obtained. The association between age-standardized DALY rates and HDI in 2013 was analyzed. The health-related Gini coefficients and the concentration indexes were calculated to explore the trends in between-country inequality in cataract burden from 1990 to 2013. RESULTS: Multiple comparison revealed that lower-HDI countries had higher age-standardized DALY rates caused by cataract. Age-standardized DALY rates were inversely associated with HDI (ß = -0.522, P < .01). From 1990 to 2013, global age-standardized DALY rates showed a trend of decline, whereas the Gini coefficients increased from 0.409 to 0.439. The concentration indexes indicated that socioeconomic-associated inequality declined in the 1990s and subsequently increased since 2000, with values of -0.259 in 1990, -0.244 in 2000, and -0.273 in 2013. CONCLUSIONS: Global health progress in cataract was accompanied by widening inequality, with cataract burden being more concentrated in countries with lower socioeconomic status. The findings highlight the need to provide more cataract services for developing countries, to combat global vision loss caused by cataract.

Assessment of Corneal Biomechanical Properties by CorVis ST in Patients with Dry Eye and in Healthy Subjects.

Purpose. To investigate corneal biomechanical properties in patients with dry eye and in healthy subjects using Corneal Visualization Scheimpflug Technology (CorVis ST). Methods. Biomechanical parameters were measured using CorVis ST in 28 eyes of 28 patients with dry eye (dry eye group) and 26 normal subjects (control group). The Schirmer I test value, tear film break-up time (TBUT), and corneal staining score (CSS) were recorded for each eye. Biomechanical properties were compared between the two groups and bivariate correlation analysis was used to assess the relationship between biomechanical parameters and dry eye signs. Results. Only one of the ten biomechanical parameters was significantly different between the two groups. Patients in the dry eye group had significantly lower highest concavity time (HC-time) (P = 0.02) than the control group. Correlation analysis showed a significant negative correlation between HC-time and CSS with marginal P value (ρ = -0.39, P = 0.04) in the dry eye group. Conclusions. The corneal biomechanical parameter of HC-time is reduced in dry eyes compared to normal eyes. There was also a very weak but significant negative correlation between HC-time and CSS in the dry eye group, indicating that ocular surface damage can give rise to a more compliant cornea in dry eyes.

Characterization, ecological risk assessment and source diagnostics of polycyclic aromatic hydrocarbons in water column of the Yellow River Delta, one of the most plenty biodiversity zones in the world.

As one of the most active regions of land-ocean interaction among the large river deltas in the world, the Yellow River Delta (YRD) gains increasing concern on its ecological and environmental conditions. However, few studies on polycyclic aromatic hydrocarbons (PAHs) have been reported for this area. In this study, the distribution characteristics, probabilistic risk and possible sources of PAHs were investigated in the water column of the YRD. The PAH concentrations were found to be at relatively low or medium levels (121.3 ng L(-1) in water and 209.1n g g(-1) in suspended particulate matter (SPM) on average), and the result of probability risk assessment additionally elucidated low PAH ecological risk in the YRD. The PAH composition showed that low and moderate molecular PAHs were the major species in water phase, whereas the SPM showed a different proportion of each PAH composition. An interesting result was found that low-ring PAHs and salinity in this land-ocean interaction area had a positive relationship (R=0.609). For PAH source identification, both diagnostic ratios of selected PAHs and principal component analysis (PCA) with multiple linear regression (MLR) analysis were studied, suggesting mixed sources of pyrogenic and petrogenic deriving PAHs in the YRD.

Pollution assessment and source identifications of polycyclic aromatic hydrocarbons in sediments of the Yellow River Delta, a newly born wetland in China.

The levels and possible sources of 16 priority polycyclic aromatic carbons (PAHs) in the sediments from the Yellow River Delta (YRD) were investigated. The total PAH concentrations ranged from 23.9 to 520.6 microg kg(-1) with a mean value of 150.9 microg kg(-1), indicating low or medium levels compared with reported values of other deltas. The concentrations of the 16 individual PAHs presented varied profiles among different regions. The ecological risk assessment of PAHs showed that adverse effects would rarely occur in the sediments of the YRD based on the effect range-low quotients and the probability risk assessment. The PAH compositions and the principal component analysis (PCA) with multiple linear regression (MLR) uniformly presumed the mixed sources of pyrogenic- and petrogenic-deriving PAHs in the YRD. By PCA with MLR, the contributions of major sources were quantified as 36.4% from oil burning, 33.1% from biomass combustion, and 30.5% from diesel emission sources.