Sedimentary record of microplastics in coastal wetland, eastern China.

Microplastic (MP) dynamics can reflect history of plastic production and waste management in nearby areas. However, the stratigraphy of MPs in coastal wetlands and their link to policy and economic pattern changes are currently unclear. Here, MP stratigraphic records in sediment core from coastal wetlands in Yancheng, China, were used to reconstruct plastic pollution history. Neural network models simulated how policy intervention and economic development affected MP accumulation over time. We showed that MP abundance curves with boundaries from 1920 to 2019 had four stages. MP growth slowed or even decreased in the mid-to-late 1980s due to improved waste management and wastewater treatment since the late 1980s. Human activities were the primary factor affecting MP abundance and shape, followed by sediment properties. We predict that the environmental impact of MPs will continue to increase in the next decade. Current plastic policy measures focus on predictable waste emissions, but hidden sources like clothing fibers and tire wear that significantly contribute to MP pollution require further attention.

Exploring the nexus of green finance and renewable energy consumption: unraveling synergistic effects and spatial spillovers.

As China transitions towards a green and low-carbon energy system, it is crucial to have the support of green finance. In this study, we explore the effects of synergy and spatial spillovers in the development of green finance and the consumption of renewable energy. By taking a synergistic perspective, we aim to provide new insights for energy structure reform. We use a spatial simultaneous equations model in combination with a three-stage generalized spatial least squares approach, our findings are the following: firstly, there is a positive synergy between the development of green finance and the consumption of renewable energy. Secondly, there are positive spatial spillovers in the development of green finance and the consumption of renewable energy, but the regional interaction effects of green finance development on renewable energy consumption are negative. Furthermore, we observe that the impact of renewable energy consumption on green finance development has been increasing since 2013. However, the reverse relationship is not true, indicating that the renewable energy industry has stabilized and is gaining appeal in financial markets. Our study highlights that the development of green finance can promote an increase in renewable energy consumption through the facilitation of economic growth, green technology innovation, and the upgrading of the industrial structure. We emphasize the importance of regional and industrial coordination to create synergy between green finance development and renewable energy consumption.

Seawater quality criteria derivation and ecological risk assessment for the neonicotinoid insecticide imidacloprid in China.

As a broad-spectrum nicotinoid insecticide, imidacloprid (IMI) has been frequently recorded in seawater environments. Water quality criteria (WQC) is the maximum concentration of chemicals, which will not pose harmful effects on aquatic species in the studied water body. Nevertheless, the WQC is not available for IMI in China, which hinders the risk assessment of this emerging pollutant. This study, therefore, aims to derive the WQC for IMI through the toxicity percentile rank (TPR) and species sensitivity distribution (SSD) methodology, and to assess its ecological risk in aquatic environments. Results showed that the recommended short-term water quality criterion (SWQC) and long-term criterion (LWQC) in seawater were derived as 0.8 µg/L and 0.056 µg/L, respectively. The ecological risk of IMI in seawater shows a wide range with hazard quotient (HQ) values of up to 11.4. The environmental monitoring, risk management and pollution control for IMI, therefore, warrant further study.

Assessment on the pollution level and risk of microplastics on bathing beaches: a case study of Liandao, China.

Microplastic pollution on bathing beaches threatens the health of human beings and coastal organisms. There is a lack of assessment on the level of microplastic pollution and the health risk associated with plastics. As one of the earliest open bathing beaches in China, Liandao is well known as the two high-quality beaches. However, little is known about the extent of microplastic pollution on these bathing beaches. Based on the analysis of microplastic pollution abundance, distribution, shape, size, color, and composition at the Liandao bathing beaches, this study puts forward a novel approach to comprehensively evaluate the microplastic pollution level and risk level by using the Nemerow pollution index (NPI) and polymer hazard index (PHI). The results show that the average abundance of microplastics on the Liandao bathing beaches is 135.42 ± 49.58 items/kg; the main shapes are fibers, fragments, and granules. Most of the microplastics are transparent, brown, and black, accounting for 71.54%, and they have an average particle size of 0.63 ± 0.43 mm. The main components are PE, PP, PS, PET, and nylon, of which nylon appears in the highest proportion (54.77%). The microplastic NPI and PHI values are 0.38 and 74.81, respectively, indicating that the pollution level and health risk index of microplastics on the Liandao bathing beaches are both low. With the increase in population and per capita consumption, plastic waste generated on land will continue to increase. Finally, this study puts forward some suggestions regarding microplastic monitoring, plastic waste management, and environmental attitudes and behavior.

Digital Divide of the Shattered "Iron Rice Bowl": Economic Insecurity and ICT Access in China.

Although economic factors account for the digital divide, the effect of economic insecurity on information communication technology (ICT) access has not been determined. The market-oriented reform of Chinese state-owned enterprises in the 1990s resulted in massive layoffs, encouraging us to investigate the relationship between economic insecurity and the digital divide. We draw on data from the China Health and Retirement Longitudinal Study (CHARLS). To handle the endogeneity related to economic insecurity, we use experience in a management position and the number of siblings as instruments for economic insecurity. With the introduction of these two instrumental variables, we find a negative relationship between economic insecurity and ICT access. This study provides insight into ICT policies involving underprivileged people in developing countries.

Assessment on the interaction between technology innovation and eco-environmental systems in China.

To investigate the latent relation between technology innovation and eco-environmental systems and promote their coordinated development, we integrated the coupling coordination model and panel vector autoregressive model to examine the evidence from China. The research reveals that the technology innovation benefit and eco-environmental governance and endowment are the prominent factors for optimizing the two systems. Moreover, the findings show that the coupling coordination degree of eco-environment and technology innovation in China presents an upward trend. In terms of the dynamic interaction between technology innovation and eco-environment, the influence of the former on the latter is timely while that of the latter on the former is lagging (except for the central region). The weak coupling coordination degree implies that the mutual promotion of technology innovation and eco-environmental systems has not yet formed. The policy implications are proposed accordingly to promote coordinated development of eco-environment and technology innovation in China.

Heterogeneous effects of environmental regulation on air pollution: evidence from China's prefecture-level cities.

Using environmental regulation to control air pollution is one of the essential means to resolve economic growth bottlenecks and ecological environment constraints. We construct a theoretical framework to analyse the impact of environmental regulation on air pollution by using balanced panel data from 2003 to 2016 of 248 Chinese cities. The results show that both formal and informal environmental regulations can significantly reduce air pollution in prefecture-level cities. Formal environmental regulation indirectly improves air pollution level by promoting technological innovation and formal environmental regulation indirectly reduces local air pollution by promoting the pollution industry transfer. In addition, informal environmental regulation indirectly reduces air pollution by improving formal environmental regulation. Moreover, formal and informal environmental regulations have inhibitory effects on air pollution in high administrative-level cities and low administrative-level cities, with both the regulations having significantly stronger inhibitory effects on air pollution in low administrative-level cities than in high administrative-level cities. Furthermore, the environmental Kuznets curve is established at the level of prefecture cities in China, and the upgrading of the industrial structure will reduce air pollution, while foreign direct investment and fiscal decentralisation will worsen air pollution.

Polycyclic aromatic hydrocarbons (PAHs) in marine organisms from two fishing grounds, South Yellow Sea, China: Bioaccumulation and human health risk assessment.

Sediment and marine organism samples collected from Haizhou Bay and Lusi fishing ground in South Yellow Sea, China were analysed for polycyclic aromatic hydrocarbons (PAHs). The concentrations of 16 PAHs in marine organisms ranged from 127.43 to 350.53 ng/g dry weight (dw, Haizhou Bay fishing ground) and from 86.37 to 213.02 ng/g dw (Lusi fishing ground). The dominant compounds were 2- and 3-ring PAHs in marine organism tissues. The main PAH sources were found to be coal combustion. Specific habitat, feeding habit, trophic level and environmental differences may affect the PAH levels in marine organisms in our study area. The biota-sediment accumulation factor (BSAF) decreased with increasing PAH log Kow and BSAF values might differ in response to various environmental conditions and species. The excess cancer risk from PAH-contaminated seafood consumption was slightly higher than the guideline value (10-6), but much lower than the priority risk level (10-4).

Impact of national Human Development Index on liver cancer outcomes: Transition from 2008 to 2018.

BACKGROUND: Liver cancer is the sixth most commonly diagnosed cancer and the fourth leading cause of cancer death worldwide. Socioeconomic development, indicated by the Human Development Index (HDI), is closely interconnected with public health. But the manner in which social development and medical advances influenced liver cancer patients in the past decade is still unknown. AIM: To investigate the influence of HDI on clinical outcomes for patients with existing liver cancer from 2008 to 2018. METHODS: The HDI values were obtained from the United Nations Development Programme, the age-standardized incidence and mortality rates of liver cancer were obtained from the GLOBOCAN database to calculate the mortality-to-incidence ratio, and the estimated 5-year net survival of patients with liver cancer was provided by the CONCORD-3 program. We then explored the association of mortality-to-incidence ratio and survival with HDI, with a focus on geographic variability across countries as well as temporal heterogeneity over the past decade. RESULTS: From 2008 to 2018, the epidemiology of liver cancer had changed across countries. Liver cancer mortality-to-incidence ratios were negatively correlated and showed good fit with a modified "dose-to-inhibition response" pattern with HDI (r = -0.548, P < 0.0001 for 2018; r = -0.617, P < 0.0001 for 2008). Cancer survival was positively associated with HDI (r = 0.408, P < 0.01) and negatively associated with mortality-to-incidence ratio (r = -0.346, P < 0.05), solidly confirming the interrelation among liver cancer outcome indicators and socioeconomic factors. Notably, in the past decade, the HDI values in most countries have increased alongside a decreasing tendency of liver cancer mortality-to-incidence ratios (P < 0.0001), and survival outcomes have simultaneously improved (P < 0.001), with significant disparities across countries. CONCLUSION: Socioeconomic factors have a significant influence on cancer outcomes. HDI values have increased along with improved cancer outcomes, with significant disparities among countries.

Characterising low-cost sensors in highly portable platforms to quantify personal exposure in diverse environments.

The inaccurate quantification of personal exposure to air pollution introduces error and bias in health estimations, severely limiting causal inference in epidemiological research worldwide. Rapid advancements in affordable, miniaturised air pollution sensor technologies offer the potential to address this limitation by capturing the high variability of personal exposure during daily life in large-scale studies with unprecedented spatial and temporal resolution. However, concerns remain regarding the suitability of novel sensing technologies for scientific and policy purposes. In this paper we characterise the performance of a portable personal air quality monitor (PAM) that integrates multiple miniaturised sensors for nitrogen oxides (NO x ), carbon monoxide (CO), ozone (O3) and particulate matter (PM) measurements along with temperature, relative humidity, acceleration, noise and GPS sensors. Overall, the air pollution sensors showed high reproducibility (mean R ¯ 2 = 0.93, min-max: 0.80-1.00) and excellent agreement with standard instrumentation (mean R ¯ 2 = 0.82, min-max: 0.54-0.99) in outdoor, indoor and commuting microenvironments across seasons and different geographical settings. An important outcome of this study is that the error of the PAM is significantly smaller than the error introduced when estimating personal exposure based on sparsely distributed outdoor fixed monitoring stations. Hence, novel sensing technologies such as the ones demonstrated here can revolutionise health studies by providing highly resolved reliable exposure metrics at a large scale to investigate the underlying mechanisms of the effects of air pollution on health.

Emission of primary microplastics in mainland China: Invisible but not negligible.

Primary microplastics are mostly produced as part of the daily plastic product use. The emission process is often invisible but poses potential ecological hazards. Thus, primary microplastics deserve public attention. Due to China's huge population base and its rapid economic development, primary microplastics emissions are of both regional and global significance. This study is the first to establish the emission inventory of primary microplastics in mainland China. It was estimated that the primary microplastic waste from mainland China amounts to 737.29 Gg, and one-sixth of this amount entered the aquatic environment in 2015. The highest proportion of this waste was attributable to tire dust and synthetic fiber, accounting for 53.91% and 28.77% of the total respectively, in mainland China. The primary microplastics emissions mainly depend on the population, followed by the level of economic development. It was roughly estimated that 538 g of microplastics is produced by each person in China. At the grid scale, the spatial difference in the total primary microplastics emissions in mainland China primarily depends on the population density distribution and transportation network. We studied the entire life cycle of several sources of microplastics, from production to discharge into the aquatic environment. We suggested different control measures under different nodes. Increasing microplastics treatment in sewage treatment plants should be a short-term viable way to achieve some measure of reduction in their entry to the environment in mainland China. Our research can not only raise public awareness about primary microplastics, but can also guide the development of environmental policies to reduce plastic pollution.

A Fuzzy Comprehensive Assessment and Hierarchical Management System for Urban Lake Health: A Case Study on the Lakes in Wuhan City, Hubei Province, China.

Environmental assessment of eutrophication or heavy metals in urban lakes is an important reference for identifying the pollution degree and formulating pollution prevention strategies. At present, the most research on lake health states is often evaluated from a single angle for toxic metals pollution or eutrophication using the standard comparison method for both, the comprehensive trophic level index (TLI), and the health risk assessment for toxic metals. Moreover, the above deterministic methods probably lead to biased or unreliable assessment due to the randomness and fuzziness in environment system caused by natural change and human activities. In this paper, a fuzzy comprehensive lake health assessment method (FCLHAM) was established to evaluate comprehensive lake health states more comprehensively and accurately, which integrates quantitative eutrophication and health risk considerations. To test and verify FCLHAM, 21 lakes, scientifically selected from the total 143 lakes in the Chinese Wuhan city as study case, were investigated and analyzed for their state of eutrophication and the health risk posed by heavy metals. According to the FCLHAM, the average comprehensive lake health state decreased in the sequence of L20 (considerate risk level) > L1⁻L17, L19, L21 (moderate risk level) > L18 (low risk level). Based on the result, lakes were classified into three categories: general management (L18), enhanced management (L1⁻L17, L19, L21), and priority management (L20). If the 143 lakes in Wuhan were classified by the "area-region-function" classification, they would be assigned to the same category as the representative lakes of the same type. At this point, we will attribute all of Wuhan's lakes to the three types. Depending on the characteristics of each type, a targeted approach to different types of management for each type of lake is a more efficient way to manage many of Wuhan's lakes. This management mode also serves as an effective reference for the environmental management of urban lakes both at home and abroad. In other words, according to the FCLHAM, a hierarchical management system based on lake characteristics classification was obtained.

Assessment of mobilization of labile phosphorus and iron across sediment-water interface in a shallow lake (Hongze) based on in situ high-resolution measurement.

The internal loading of P is reported to be the main factor initiating algal blooms. However, there are only a few reports on the dynamic variation of labile P in the sediment and overlying water during the decomposition of algal. In addition, the widely perceived relationship between labile P and Fe was not supported by in situ obtained values in freshwater. Consequently, the in situ simultaneous measurement of diffusion gradients in thin-film techniques (DGT) was applied on a large scale to detect the mechanisms of labile P and Fe in a typical shallow lake (Lake Hongze). The newly developed ZrO-DGT and ZrO-Chelex DGT were combined to obtain the concentration of labile P and Fe. Results showed that decomposition of algal might be the main contributor for the concentration dots and peaks of labile P in sediment profiles, as well as for the high values on the horizontal heterogeneity index of labile P at the depth of 0-30 mm of the sediment. Moreover, there existed significant difference between the apparent diffusion fluxes of labile P and Fe across the sediment-water interface which obtained from June sampling and October sampling. The results of apparent diffusion flux in two periods indicated the sediments changed from "sink" to "source" for labile P, especially at Sites 4-8, 10, 13-14, and 18. However, the role of the labile Fe has no significantly variation in the values of the diffusion flux. This phenomenon also contributed to the poor relationship between labile P and Fe in the sediment which obtained from the October sampling. Accordingly, we conclude that algal decomposition might be essential for internal loading of P in this aquatic ecosystem, and that also be the reason for vicious circle of algal occurrence in the following year in the center of Lake Hongze.

Duplexed on-microbead binding assay for competitive inhibitor of epidermal growth factor receptor by quantitative flow cytometry.

Upon binding agonist, the epidermal growth factor receptor (EGFR) is dimerized and auto-phosphorylated to activate downstream pathway that induces diverse physiology and pathology processes. Conventional methods for evaluation of EGFR inhibitors are limited. This study describes a duplexed on-microbead binding assay allowing competitive EGFR inhibitors to be quantificationally evaluated in vitro. Polystyrene microbeads barcoded by fluoresceine isothiocyanate fluorescence as high brightness and low brightness microspheres were coated with receptor tyrosine kinase (RTK) ligand-epidermal growth factor (EGF)/stem cell factor (SCF) and ATP/GTP, respectively. High and low brightness microbeads were mixed and incubated with EGFR and its competitive inhibitor in binding assay buffer. Phycoerythrin (PE) fluorescence-labelled antibody was employed to report the level of EGFR binding to EGF/SCF and ATP/GTP. Values were numbered via PE molecules assessed by quantitative flow cytometry. Results from this study demonstrated that incubation with EGFR identified by PE-labelled antibody can make EGF- and ATP-coated microbeads luminous. And EGF or ATP-competitive EGFR inhibitors, respectively, alleviated this in a concentration-dependent manner. Coating microbeads with SCF or GTP as a negative control cannot capture EGFR. The duplexed on-microbead binding assay in this study might be useful for discovering ligand- and ATP-competitive EGFR inhibitors in a rapid and quantificational approach.