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1.
Sci Total Environ ; 943: 173761, 2024 Sep 15.
Artigo em Inglês | MEDLINE | ID: mdl-38851355

RESUMO

Acephate is commonly used as a seed treatment (ST) in precision agriculture, but its impact on pollinators, earthworms, and soil microorganisms remains unclear. This study aimed to compare the fate of acephate seed dressing (SD) and seed coating (SC) treatments and assess potential risks to bees, earthworms, and soil microorganisms. Additionally, a follow-up study on maize seeds treated with acephate in a greenhouse was conducted to evaluate the maize growth process and the dissipation dynamics of the insecticide. The results indicated that acephate SC led to greater uptake and translocation in maize plants, resulting in lower residue levels in the soil. However, high concentrations of acephate metabolites in the soil had a negative impact on the body weight of earthworms, whereas acephate itself did not. The potential risk to bees from exposure to acephate ST was determined to be low, but dose-dependent effects were observed. Furthermore, acephate ST had no significant effect on soil bacterial community diversity and abundance compared to a control. This study provides valuable insights into the uptake and translocation of acephate SD and SC, and indicates that SC is safer than SD in terms of adverse effects on bees and nontarget soil organisms.


Assuntos
Agricultura , Inseticidas , Oligoquetos , Fosforamidas , Sementes , Microbiologia do Solo , Zea mays , Animais , Abelhas/fisiologia , Agricultura/métodos , Inseticidas/toxicidade , Poluentes do Solo/toxicidade , Compostos Organotiofosforados/toxicidade , Solo/química
2.
J Vasc Surg ; 80(2): 574-585.e4, 2024 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-38580159

RESUMO

OBJECTIVE: Although carotid body tumors (CBTs) are rare, they attract particular attention because of their propensity for malignant transformation and the high surgical risk. Because data are scarce and as it is difficult to achieve a large sample size, no study has yet comprehensively analyzed the characteristics, management, or operative complications of CBTs. Therefore, we collected and analyzed all currently available information on CBTs and used the pooled data to derive quantitative information on disease characteristics and management. METHODS: We systematically searched PubMed, Embase, the Cochrane Library, and the Web of Science up to December 1, 2022, for studies that investigated the characteristics and management of CBTs. The primary objective was to identify the prevalence of the various characteristics and the incidence of complications. The secondary objective was to compare patients who underwent preoperative embolization (PE) and those who did not (non-PE), as well as to compare patients with different Shamblin grades and those with and without succinate dehydrogenase (SDH) mutations in terms of CBT characteristics and complications. Two reviewers selected studies for inclusion and independently extracted data. All statistical analyses were performed using the standard statistical procedures of Review Manager 5.2 and Stata 12.0. RESULTS: A total of 155 studies with 9291 patients and 9862 tumors were identified. The pooled results indicated that the median age of patients with CBT was 45.72 years, and 65% were female. The proportion of patients with bilateral lesions was 13%. In addition, 16% of patients had relevant family histories, and the proportion of those with SDH gene mutations was 36%. Sixteen percent of patients experienced multiple paragangliomas, and 12% of CBTs had catecholamine function. The incidence of cranial nerve injury (CNI) was 27%, and 14% of patients suffered from permanent CNI. The incidence rates of operative mortality and stroke were both 1%, and 4% of patients developed transient ischemic attacks. Of all CBTs, 6% were malignant or associated with metastases or recurrences. The most common metastatic locations were the lymph nodes (3%) and bone (3%), followed by the lungs (2%). Compared with non-PE, PE reduced the estimated blood loss (standardized mean difference, -0.95; 95% confidence interval [CI], -1.70 to -0.20) and the operation time (standardized mean difference, -0.56; 95% CI, -1.03 to -0.09), but it increased the incidence of stroke (odds ratio, 2.44; 95% CI, 1.04-5.73). Higher Shamblin grade tumors were associated with more operative complications. Patients who were SDH gene mutation-positive were more likely to have a relevant family history and had more symptoms. CONCLUSIONS: CBT was most common in middle-aged females, and early surgical resection was feasible; there was a low incidence of serious operative complications. Routine PE is not recommended because this may increase the incidence of stroke, although PE somewhat reduced the estimated blood loss and operation time. Higher Shamblin grade tumors increased the incidence of operative complications. Patients who were SDH gene mutation-positive had the most relevant family histories and symptoms.


Assuntos
Tumor do Corpo Carotídeo , Embolização Terapêutica , Humanos , Tumor do Corpo Carotídeo/cirurgia , Tumor do Corpo Carotídeo/epidemiologia , Tumor do Corpo Carotídeo/terapia , Tumor do Corpo Carotídeo/genética , Prevalência , Fatores de Risco , Feminino , Masculino , Embolização Terapêutica/efeitos adversos , Resultado do Tratamento , Pessoa de Meia-Idade , Adulto , Medição de Risco , Idoso , Adulto Jovem , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Adolescente , Mutação
3.
Huan Jing Ke Xue ; 45(3): 1769-1780, 2024 Mar 08.
Artigo em Chinês | MEDLINE | ID: mdl-38471888

RESUMO

To further explore the characteristics of heavy metal pollution and the ecological risk of typical industries in reclaimed soil, based on data from 315 different depth profiles of soil samples collected from 49 plots in Jiading District, Shanghai, the geo-accumulation index and potential ecological risk index were used to evaluate the contents and potential ecological risk of seven heavy metals, namely Cd, Pb, Cu, Zn, Ni, Hg, and As. The APCS-MLR receptor model and PMF positive matrix factorization model were employed to analyze the pollution sources. The results showed that:① except for As, the contents of other heavy metals in the soil of the study area exceeded the Shanghai soil background values to varying degrees. The contents of Cd, Pb, Cu, Zn, Ni, and Hg in the surface soil were 3.54, 2.34, 2.91, 1.20, 3.75, and 4.40 times the background values, respectively. The contents of heavy metals in the soil decreased with the increase in depth, and heavy metals were enriched to a certain extent in the surface soil, indicating that human activities had an impact on the distribution of heavy metals in the soil. ② The APCS-MLR and PMF receptor models identified four main sources of soil heavy metals in the study area. Source 1 (Cu, Zn, and Pb) was a mixture of metal products and automobile manufacturing, source 2 (Ni and Cd) was electroplating enterprises, source 3 (Hg) was mainly from chemical enterprises, and source 4 (As) was natural. The combined use of the two receptor models further improved the accuracy and credibility of source identification. ③ The geo-accumulation index in descending order was Hg(1.54)>Ni(1.32)>Cd(1.21)>Cu(0.96)>Pb(0.64)>Zn(-0.33)>As(-1.02). The potential ecological risk index showed that the comprehensive potential ecological risk index RI value in the study area ranged from 32.50 to 4 910.97, with a mean of 321.40, indicating a strong potential ecological risk. The pollution values of heavy metals Hg, Ni, and Cd in industrial site soil deserve further attention for re-development and utilization purposes.

4.
Calcif Tissue Int ; 114(4): 368-376, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38376758

RESUMO

The study addresses the challenge of treating secondary hyperparathyroidism (SHPT) in chronic kidney disease (CKD) patients, focusing on the cost-effectiveness of surgical versus pharmacological interventions. Conducting a retrospective analysis on 152 CKD patients with SHPT at the Third People's Hospital of Chengdu, the study matched 80 patients into two groups: 40 undergoing parathyroidectomy with autotransplantation (PTX + AT) and 40 treated with calcimimetics. PTX + AT was more effective in alleviating symptoms, particularly bodily pain, and demonstrated greater cost-effectiveness over a long-term period compared to calcimimetics. This was especially significant in patients with PTH levels > 1800 pg/mL and hyperphosphatemia. Despite similar initial costs, PTX + AT led to a substantial decrease in expenses during the 2-5 years post-treatment period, PTX + AT results in an ICER of -RMB 26.71/QALY for the first post-treatment year and -RMB-111.9k/QALY for the 2-5 year period, indicating cost-effectiveness with reduced long-term costs. The study also found an increased economic burden in managing patients with hyperphosphatemia. Surgical intervention (PTX + AT) is advocated as the primary treatment strategy for severe SHPT in CKD patients, owing to its long-term economic and clinical advantages. The results underscore the need for a severity-based approach in treating SHPT.


Assuntos
Hiperparatireoidismo Secundário , Hiperfosfatemia , Insuficiência Renal Crônica , Humanos , Estudos Retrospectivos , Análise Custo-Benefício , Hiperparatireoidismo Secundário/cirurgia , Hiperparatireoidismo Secundário/tratamento farmacológico , Insuficiência Renal Crônica/complicações , Paratireoidectomia/métodos , Hormônio Paratireóideo/uso terapêutico
5.
Artigo em Inglês | MEDLINE | ID: mdl-38083204

RESUMO

Cephalometric analysis plays an important role in orthodontic diagnosis and treatment planning. It depends on the detection of multiple landmarks, while the process is time-consuming and tedious. Although some deep learning-based automatic landmark detection algorithms have achieved excellent performance, most of them adopt multi-stage models increasing the complexity and detection time. Meanwhile, few studies focused on the uncertainty of detection results, thereby ignoring its significant clinical value. In this paper, we propose a novel approach based on heatmap regression for landmark detection, which can achieve competitive accuracy and good robustness with only one step. Furthermore, by applying Monte Carlo dropout to a U-shaped convolutional neural network, we can obtain not only the coordinate of each landmark but also the corresponding simple uncertainty, so that doctors can pay more attention to those landmarks with higher uncertainty. The evaluation results showed the mean radial error is 1.39±1.06mm and the average successful detection rate is 79.65%, 97.22% within 2mm, 4mm for the IEEE ISBI2015 Test Dataset 1, the indicators for the IEEE ISBI2015 Test Dataset 2 are 1.33±0.93mm, 80.05% and 97.53%, respectively. Our method has the potential to become an assistant tool in clinical practice. Automatic and accurate detection with uncertainty analysis is expected to help guide the doctor's judgment.


Assuntos
Algoritmos , Redes Neurais de Computação , Reprodutibilidade dos Testes , Cefalometria/métodos , Radiografia
6.
BMC Med Imaging ; 23(1): 215, 2023 12 18.
Artigo em Inglês | MEDLINE | ID: mdl-38110909

RESUMO

PURPOSE: Retroperitoneal liposarcoma (RLPS) poses a challenging scenario for surgeons due to its unpredictable biological behavior. Surgery remains the primary curative option for RLPS; however, the need for additional information to guide surgical strategies persists. Volume-based 18F-FDG PET/CT may solve this issue. METHODS: We analyzed data from 89 RLPS patients, measuring metabolic tumor volume (MTV), total lesion glycolysis (TLG), and maximum standardized uptake value (SUVmax) and explored their associations with clinical, prognostic, and pathological factors. RESULTS: MTV, TLG of multifocal and recurrent RLPS were significantly higher than unifocal and primary ones (P < 0.001, P < 0.001, P = 0.003 and P = 0.002, respectively). SUVmax correlated with FNCLCC histological grade, mitotic count and Ki-67 index (P for G1/G2 = 0.005, P for G2/G3 = 0.017, and P for G1/G3 = 0.001, P < 0.001 and P = 0.024, respectively). MTG, TLG and SUVmax of WDLPS were significantly lower than DDLPS and PLPS (P for MTV were 0.009 and 0.022, P for TLG were 0.028 and 0.048, and P for SUVmax were 0.027 and < 0.001, respectively). Multivariable Cox analysis showed that MTV > 457.65 (P = 0.025), pathological subtype (P = 0.049) and FNCLCC histological grade (P = 0.033) were related to overall survival (OS). CONCLUSIONS: Our findings indicate that MTV is an independent prognostic factor for RLPS, while MTV, TLG, and SUVmax can preoperatively predict multifocal lesions, histological grade, and pathological subtype. Volume-based 18F-FDG PET/CT offers valuable information to aid in the decision-making process for RLPS surgical strategies.


Assuntos
Fluordesoxiglucose F18 , Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada , Humanos , Estudos Retrospectivos , Prognóstico , Carga Tumoral , Compostos Radiofarmacêuticos
7.
BMC Geriatr ; 23(1): 457, 2023 07 25.
Artigo em Inglês | MEDLINE | ID: mdl-37491188

RESUMO

BACKGROUND: The increasing prevalence of Chronic Obstructive Pulmonary Disease (COPD) has imposed a considerable economic burden. However, there remains a paucity of relevant evidence regarding the hospitalization costs of COPD cases. Therefore, in this study, we aimed to assess the hospitalization costs among COPD cases and investigate the factors that contribute to their costs in Henan Province, China. METHODS: We enrolled a total of 1697 cases who were discharged with a diagnosis of COPD from January 1, 2020 to December 31, 2020, into the study. Demographic and clinical characteristics of the cases were obtained from the hospital information system (HIS) of two large tertiary hospitals in Henan Province, China. The factors associated with hospitalization costs were examined using a multiple linear regression model. RESULTS: Total hospitalization costs of 1697 COPD cases were $5,419,011, and the median was $1952 (IQR:2031). Out-of-pocket fees accounted for 43.95% of the total hospitalization costs, and the median was $938 (IQR:956). Multiple linear regression analysis revealed that hospitalization costs were higher among older cases, cases with more comorbidities, and cases with longer length of stay. Furthermore, hospitalization costs were higher in cases who paid through private expenses compared to those covered by Urban Employee Basic Medical Insurance. Additionally, we found that cases admitted through an outpatient clinic had higher hospitalization costs than those admitted through the emergency department. CONCLUSION: Hospitalization costs of COPD cases are substantial. Strategies to reduce hospitalization costs, such as shortening LOS, optimizing payment plans, and preventing or managing complications, should be implemented to alleviate the economic burden associated with COPD hospitalizations.


Assuntos
Hospitalização , Doença Pulmonar Obstrutiva Crônica , Humanos , Centros de Atenção Terciária , Doença Pulmonar Obstrutiva Crônica/diagnóstico , Doença Pulmonar Obstrutiva Crônica/epidemiologia , Doença Pulmonar Obstrutiva Crônica/terapia , Comorbidade , China/epidemiologia , Estudos Retrospectivos
8.
Environ Res ; 231(Pt 1): 115943, 2023 Aug 15.
Artigo em Inglês | MEDLINE | ID: mdl-37084946

RESUMO

While significant reductions in certain air pollutant concentrations did not induce obvious mitigations of health risks, a shift from air quality management to health risk prevention and control might be necessary to protect public health. This study thus constructed an Air Quality Health Index (AQHI) for respiratory (Res-AQHI), cardiovascular (Car-AQHI), and allergic (Aller-AQHI) risk groups using mixed exposure under multi-air pollutants and portrayed their distribution and variation at multiple spatiotemporal scales using spatial analysis in GIS with the medical big data and air pollution remote sensing data by taking Hunan Province in China as a case. Results showed that the AQHIs constructed for specific health-risk groups could better express their risks than common AQHI and AQI. Moreover, based on the spatiotemporal association of health and environmental information, the allergic risk group in Hunan provided the highest health risk mainly affected by O3. The following cardiovascular and respiratory risk groups can be significantly attributed to NO2. Moreover, the spatiotemporal heterogeneity of AQHIs within regions was also evident. On the annual scale, the population in the air health risk hotspots for respiratory and cardiovascular risk decreased, while allergic risks increased. Meanwhile, on seasonal scale, the hotspots for respiratory and cardiovascular risks expanded significantly in winter while completely disappearing for allergic risk. These findings suggest that disease specific AQHIs effectively disclose the health effects of multi-air pollutants and their subsequently varied spatiotemporal distribution patterns.


Assuntos
Poluentes Atmosféricos , Poluição do Ar , Poluentes Atmosféricos/toxicidade , Poluentes Atmosféricos/análise , Material Particulado/toxicidade , Material Particulado/análise , Poluição do Ar/análise , Medição de Risco , China
9.
BMC Med ; 21(1): 159, 2023 04 27.
Artigo em Inglês | MEDLINE | ID: mdl-37106459

RESUMO

BACKGROUND: Effective risk prediction models are lacking for personalized endoscopic screening of gastric cancer (GC). We aimed to develop, validate, and evaluate a questionnaire-based GC risk assessment tool for risk prediction and stratification in the Chinese population. METHODS: In this three-stage multicenter study, we first selected eligible variables by Cox regression models and constructed a GC risk score (GCRS) based on regression coefficients in 416,343 subjects (aged 40-75 years) from the China Kadoorie Biobank (CKB, development cohort). In the same age range, we validated the GCRS effectiveness in 13,982 subjects from another independent Changzhou cohort (validation cohort) as well as in 5348 subjects from an endoscopy screening program in Yangzhou. Finally, we categorized participants into low (bottom 20%), intermediate (20-80%), and high risk (top 20%) groups by the GCRS distribution in the development cohort. RESULTS: The GCRS using 11 questionnaire-based variables demonstrated a Harrell's C-index of 0.754 (95% CI, 0.745-0.762) and 0.736 (95% CI, 0.710-0.761) in the two cohorts, respectively. In the validation cohort, the 10-year risk was 0.34%, 1.05%, and 4.32% for individuals with a low (≤ 13.6), intermediate (13.7~30.6), and high (≥ 30.7) GCRS, respectively. In the endoscopic screening program, the detection rate of GC varied from 0.00% in low-GCRS individuals, 0.27% with intermediate GCRS, to 2.59% with high GCRS. A proportion of 81.6% of all GC cases was identified from the high-GCRS group, which represented 28.9% of all the screened participants. CONCLUSIONS: The GCRS can be an effective risk assessment tool for tailored endoscopic screening of GC in China. Risk Evaluation for Stomach Cancer by Yourself (RESCUE), an online tool was developed to aid the use of GCRS.


Assuntos
Neoplasias Gástricas , Humanos , Detecção Precoce de Câncer , População do Leste Asiático , Medição de Risco , Fatores de Risco , Neoplasias Gástricas/diagnóstico , Neoplasias Gástricas/epidemiologia , Adulto , Pessoa de Meia-Idade , Idoso
10.
Acta Cardiol ; 78(4): 423-432, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-37039610

RESUMO

BACKGROUND: Non-invasive right ventricular (RV) myocardial work (RVMW) is the latest indicator used to assess RV function. Nevertheless, the physiological determinants of RVMW have not been studied, and reference ranges for normal RVMW indices have yet to be established. METHODS: A total of 263 healthy volunteers (median age: 34 years, males: 38%) were prospectively enrolled. RVMW indices were analysed by an RV pressure-strain loop (RVPSL) in specific software. RESULTS: The lowest values of the RVMW indices in males and females were 133 mmHg% and 206 mmHg% for RV global work index (RVGWI), 165 mmHg% and 241 mmHg% for RV global constructive work (RVGCW) and 78% and 83% for RV global work efficiency (RVGWE), respectively. The highest values for RV global wasted work (RVGWW) in males and females were 67 mmHg% and 69 mmHg%, respectively. RVGWI and RVGCW were significantly lower in males than those in females. RVGWW significantly increased with age in males and females. RVGWE significantly decreased with age in females. Multivariable analysis revealed that RVGWI, RVGCW and RVGWE increased as pulmonary artery systolic pressure (PASP) increased. CONCLUSIONS: Normal reference values of non-invasive RVMW were obtained by echocardiography. Quantitative data on RVMW could be essential in clinical work and clinical experiments.


Assuntos
Ecocardiografia , Disfunção Ventricular Direita , Masculino , Feminino , Humanos , Adulto , Função Ventricular Direita/fisiologia , Valores de Referência , Software , Voluntários Saudáveis
11.
IEEE Trans Vis Comput Graph ; 29(6): 2849-2861, 2023 06.
Artigo em Inglês | MEDLINE | ID: mdl-37030774

RESUMO

Collusive fraud, in which multiple fraudsters collude to defraud health insurance funds, threatens the operation of the healthcare system. However, existing statistical and machine learning-based methods have limited ability to detect fraud in the scenario of health insurance due to the high similarity of fraudulent behaviors to normal medical visits and the lack of labeled data. To ensure the accuracy of the detection results, expert knowledge needs to be integrated with the fraud detection process. By working closely with health insurance audit experts, we propose FraudAuditor, a three-stage visual analytics approach to collusive fraud detection in health insurance. Specifically, we first allow users to interactively construct a co-visit network to holistically model the visit relationships of different patients. Second, an improved community detection algorithm that considers the strength of fraud likelihood is designed to detect suspicious fraudulent groups. Finally, through our visual interface, users can compare, investigate, and verify suspicious patient behavior with tailored visualizations that support different time scales. We conducted case studies in a real-world healthcare scenario, i.e., to help locate the actual fraud group and exclude the false positive group. The results and expert feedback proved the effectiveness and usability of the approach.


Assuntos
Gráficos por Computador , Mineração de Dados , Humanos , Mineração de Dados/métodos , Seguro Saúde , Algoritmos , Fraude
12.
Echocardiography ; 40(2): 113-127, 2023 02.
Artigo em Inglês | MEDLINE | ID: mdl-36647764

RESUMO

BACKGROUND: Tricuspid annulus (TA) geometry and function reference values are limited, especially for Asian populations. We aimed to explore TA using four-dimensional echocardiography (4DE) in a healthy Asian population. METHODS: A total of 355 healthy Asian volunteers (median age 34 years; 52% males) were prospectively enrolled. TA geometry and function were analyzed using 4DE throughout the cardiac cycle. RESULTS: The TA area, perimeter, and dimensions were smallest at end systole (ES) and largest at late diastole (LD). Normal TA parameters at end diastole (ED) in different sex and age groups were obtained. TA areas, perimeters, and dimensions in males were significantly larger than those in females at ED; BSA-indexed perimeters and BSA-indexed dimensions in males were significantly smaller than those in females at ED. TA parameters correlated well with tricuspid valve (TV) tenting, right ventricle (RV), and right atrium (RA) parameters. CONCLUSIONS: Reference values of TA parameters were obtained by 4DE in an Asian population. Quantitative data on TA geometry and function are essential for TA pathology and therapeutics.


Assuntos
Ecocardiografia Tridimensional , Insuficiência da Valva Tricúspide , Masculino , Feminino , Humanos , Adulto , Ecocardiografia Quadridimensional , Ecocardiografia Tridimensional/métodos , Valva Tricúspide , Átrios do Coração/diagnóstico por imagem
13.
Environ Sci Pollut Res Int ; 30(10): 25037-25049, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-34091846

RESUMO

At present, China's carbon emissions rank first in the world, which not only brings huge challenges to the sustainable development of China's economy, but also brings more pressure from public opinion in the international community. With the outward migration of China's manufacturing industries to Southeast Asia, the carbon emissions embodied in trade has also been transferred. These trends provide a good opportunity to analyze the characteristics of transnational industrial restructuring and spatial structure transformation of carbon emissions between China and Southeast Asian countries. In 2020, ASEAN has become China's largest trading partner, and Thailand, due to its unique industrial structure and investment environment, will surely become one of the main ASEAN countries to undertake the transfer of China's manufacturing industry. Over the years, the shift of carbon emissions by the continuous transfer of a large number of basic manufacturing industries from China to Thailand promoted the release of China's carbon emission pressure. In this article, on the basis of the data of import and export commodities between China and Thailand from 2012 to 2017, the input-output model is carried out to analyze the energy consumption of China's various industries, and three periods, namely 2012, 2015, and 2017, are used to be key periods to calculate the embodied carbon of China's manufacturing migration and Sino-Thailand trade. The empirical results show that the transfer of China's manufacturing to Thailand from 2012 to 2017 has continued to rise. The transfer of Chinese manufacturing to Thailand is positively correlated with the carbon emissions of trade between the two countries, which has promoted the relief of China's pressure on energy conservation and emission reduction. Therefore, government departments should formulate differentiated and stable domestic manufacturing policies, spend on the development of advanced manufacturing industries with low energy consumption and high technology density, and encourage the relocation of industries with low technology density and high-carbon emissions to effectively reduce environmental pressure in China.


Assuntos
Dióxido de Carbono , Carbono , Carbono/análise , Dióxido de Carbono/análise , China , Indústrias , Indústria Manufatureira , Desenvolvimento Econômico
14.
Environ Sci Pollut Res Int ; 30(8): 21588-21597, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36272005

RESUMO

Bifenthrin is a pyrethroid pesticide widely used on kumquats, but the residues in the peel and pulp after bifenthrin application at different maturity stages of kumquats have not been evaluated. This study developed a simple and rapid high-performance liquid chromatography (HPLC) method for the quantitative analysis of bifenthrin residues in whole fruit, kumquat peel, kumquat pulp, and soil. The results showed that regardless of whether bifenthrin was applied one or three times during the near-mature period, the half-lives of the fruit peel and fruit pulp were longer than those in the immature period. Kumquat fruit residues decreased with time at both maturity levels. The residues of bifenthrin in near-mature fruit exceeded the MRL in Guangxi and Fujian 14 days after the three applications of bifenthrin, suggesting that this issue should be focused on in kumquat production and supervision. However, for bifenthrin application in either the near-mature or the immature fruit period, the calculated risks for chronic dietary intake of kumquat were well below 100%. The data demonstrate that the chronic dietary intake risk of bifenthrin through kumquat consumption is low and within acceptable limits. These results provide a reference and risk assessment data for the safe and rational use of bifenthrin insecticides.


Assuntos
Citrus , Resíduos de Praguicidas , Piretrinas , Rutaceae , Frutas/química , Citrus/química , China , Piretrinas/análise , Medição de Risco , Ingestão de Alimentos , Resíduos de Praguicidas/análise
15.
BMC Med Inform Decis Mak ; 22(1): 299, 2022 11 17.
Artigo em Inglês | MEDLINE | ID: mdl-36397038

RESUMO

BACKGROUND: Achieving healthy ageing has become the only way for China to alleviate the pressure of ageing, especially in rural areas. However, the factors affecting the health of rural older adults are numerous and complex. It is important to identify the critical factors that affecting the health of older adults in rural areas and provide decision-making support for targeted health interventions. METHODS: To overcome some limitations of existing works, an extended probabilistic linguistic fuzzy cognitive map model is proposed in this paper as a useful tool for modeling the cause-effect relationship between factors. The proposed model integrates the advantages of probabilistic linguistic term sets and fuzzy cognitive maps. In the end, to rank and identify the critical factors affecting the health, a novel similarity measure based on Euclidean distance and Z-mapping function is proposed. RESULTS: The proposed model can effectively deal with the uncertainty of experts and reflect different opinions of groups well. In terms of representing uncertainty and ambiguity, the proposed method outperforms other models in modeling complex systems. In the real-world case analysis, we find that education is the most important factor affecting the health of rural older adults, followed by previous occupational experiences, psychology, and physical exercise, among other things. Intergenerational relationship has become another important factor affecting the health of rural older adults in China as the development of Chinese society. CONCLUSIONS: From a macro perspective, social economic status, living environment, lifestyle, and health management, are the variables that have the greatest impact on the health of rural older adults. As a result, providing more precise health interventions with the characteristics of factors influencing health is a crucial guarantee for preserving and improving the health of rural older adults in China.


Assuntos
Linguística , População Rural , Humanos , Idoso , China , Fatores Socioeconômicos , Cognição
16.
Artigo em Inglês | MEDLINE | ID: mdl-36429366

RESUMO

Heavy metals in freshwater lake sediments often exist in various chemical forms. However, the investigation and evaluation of heavy-metal elements in the sediments of the study area have not been reported, and there is a lack of objective understanding of the concentration level of heavy-metal elements. Therefore, this study is the first to report the concentrations, sources, and potential ecological risks of heavy metals in the sediments of Chengdong Lake and Chengxi Lake in Huoqiu County, Anhui Province, China. The spatial distribution, pollution characteristics, potential pollution sources, and ecological risks of heavy metals in the sediments of Chengxi Lake and Chengdong Lake of Huoqiu City in the middle section of Huaihe River in Anhui Province, China have not been reported. In this study, the sediment samples of the two Lakes were collected systematically, and the concentrations of heavy metals (As, Cd, Cr, Cu, Hg, Ni, Pb, and Zn) were determined. The potential sources of heavy-metal elements in sediments were quantitatively analyzed according to the principal component analysis-absolute principal component fraction-multiple linear regression (PCA-APCS-MLR) receptor model. Descriptive statistics data showed that the enrichment degree of heavy metals in Chengxi Lake was higher than that in Chengdong Lake. The geo-accumulation index (Igeo) and pollution load index (PLI) indicated that there was moderate pollution for Cu, As, Hg, Ni, and Zn. The calculation results of the potential ecological risk index (Er) of the two lakes indicated that Cd (Er,max = 92.22, n = 60) and Hg (Er,max = 64.39, n = 60) showed a certain potential ecological risk in a small amount of sediment, while other heavy metals were classified as low risk. The mean sediment quality guideline quotient indicated that there was a moderate degree of potential adverse biological toxicity in lake sediments. Spatially, the seriously polluted contamination zones were the central position of Chengxi Lake and the northeast end of Chengdong Lake. The PCA-APCS-MLR receptor model revealed that Cr, Ni, Cu, and Zn were mainly from natural sources while Cd, As, Hg, and Pb elements were mainly from industrial sources and pesticide sources.


Assuntos
Mercúrio , Metais Pesados , Poluentes Químicos da Água , Lagos , Rios , Sedimentos Geológicos/análise , Cádmio/análise , Chumbo/análise , Monitoramento Ambiental , Poluentes Químicos da Água/análise , Metais Pesados/análise , Mercúrio/análise , Medição de Risco
17.
Artigo em Inglês | MEDLINE | ID: mdl-36293633

RESUMO

The eutrophication of coastal water has been a critical environmental problem in China's offshore areas. How to effectively assess the status of coastal waters is key for pollution treatment and environmental protection. In recent years, eutrophication-symptom-based and multi-indicator methods, termed "phase II" methods, have been gradually adopted to assess the eutrophication status in some coastal waters in China and have achieved success. The cumulative quantile is typically selected to determine the characteristic value of an indicator in "phase II" methods. The influence of small-scale damaged water bodies on eutrophication assessment may be exaggerated, which often leads to the overassessment of the eutrophication status. In this study, the area ratio method was integrated into the assessment of the estuarine trophic status (ASSETS) method in order to assess the eutrophication status of Xiamen Bay in 2016. The results indicated that, in 2016, the eutrophication status of Xiamen Bay coastal waters was moderate and exhibited spatiotemporal variation. The area ratio method can effectively reduce the effect of small-scale coastal waters with extremely high eutrophication on the overassessment of eutrophication at the broader scale, allowing the eutrophication status to be better reflected, even with limited observation data. The centralized distribution of pollution sources and poor hydrodynamic conditions are the main reasons for the aforementioned phenomenon. Controlling the pollution discharge from the Jiulong River in flood seasons is key to reducing eutrophication in Xiamen coastal waters.


Assuntos
Baías , Monitoramento Ambiental , Monitoramento Ambiental/métodos , Eutrofização , Rios , Água , China
18.
Huan Jing Ke Xue ; 43(9): 4791-4799, 2022 Sep 08.
Artigo em Chinês | MEDLINE | ID: mdl-36096619

RESUMO

In order to study the distribution characteristics and potential risk of antimony (Sb) in urban soil, the concentrations of soil Sb in four different land use types were analyzed based on the data of 1670 soil samples with different vertical profiles in 102 plots in Shanghai. The risks were evaluated using the potential ecological risk index method and health risk assessment model. The results showed that the average ω(Sb) in the study area was 0.52 mg·kg-1, and the content of soil Sb gradually declined with the rise in soil profile depth. Sb was enriched in surface soil, which indicated that human activities had caused disturbance to the distribution of Sb in the soil. The content of Sb in the surface soil of industrial land was higher than that of residential land and commercial land, and the content of Sb in agricultural land was the lowest. The single-factor pollution index of industrial land was the highest, reaching a slight pollution level, whereas the residential land, commercial land, and agricultural land were at even-clean or clean levels, respectively. The whole region showed slight ecological risk, with the potential ecological risk index ranging from 4.23 to 7.61. The potential ecological risk level of industrial land was moderate, which needs to be addressed. The results of health risk assessment showed that the non-carcinogenic risk of Sb in the soil was low; however, it is of great concern to residents, especially children, when on residential land.


Assuntos
Metais Pesados , Poluentes do Solo , Antimônio , Criança , China , Monitoramento Ambiental/métodos , Humanos , Metais Pesados/análise , Medição de Risco , Solo , Poluentes do Solo/análise
19.
Toxics ; 10(8)2022 Jul 29.
Artigo em Inglês | MEDLINE | ID: mdl-36006113

RESUMO

BACKGROUND: As a systematic fungicide, prochloraz is often used to control banana freckle disease, and it is significant to assess the safety and risk of prochloraz. METHODS: The dissipation kinetics and distribution of prochloraz in bananas were measured by high-performance liquid chromatography (HPLC). RESULTS: The results showed that the fortified recoveries in bananas were 83.01-99.12%, and the relative standard deviations (RSDs) were 2.45-7.84%. The half-life of prochloraz in banana peel (3.93-5.60 d) was significantly lower than it was in whole banana (8.25-10.80 d) and banana pulp (10.35-12.84 d). The terminal residue of prochloraz in banana fruits was below the maximum residue level (MRL, China) at pre-harvest intervals (PHI) of 21 d. Moreover, the residue of prochloraz in banana peel was always 1.06-7.71 times greater than it was in banana pulp. The dietary risk assessment results indicated that the prochloraz residue in bananas at PHI of 21 d was safe for representative populations. (4) Conclusions: We found that a 26.7% prochloraz emulsion oil in water (EW) diluted 1000-fold and sprayed three times under field conditions was safe and reliable, providing a reference for the safe application of prochloraz in bananas.

20.
Artigo em Inglês | MEDLINE | ID: mdl-35955041

RESUMO

Understanding the extent of contamination, sources and various carcinogenic and non-carcinogenic risks associated with different heavy metals in soil-crop systems is crucial for the prevention of heavy metal pollution. A survey was undertaken to determine heavy metal concentrations and degree of pollution in soil-crop systems (rice, wheat, and corn) using various indices such as pollution factor (CF), geo-accumulation index (Igeo), enrichment coefficients and transfer coefficient, and to determine the source of heavy metals pollution in the Wanjiang Economic Zone, Anhui Province, China. A total of 308 pairs of soil-crop samples were collected in this study, comprising 245 pairs of soil-rice samples, 53 pairs of soil-wheat samples, and 10 pairs of soil-corn samples. The concentrations of cadmium (Cd) and nickel (Ni) in the soil of the study area exceeded the national limitation of heavy metals in the soil of China (GB 15618-2018, Soil Environmental Quality: Risk Control Standard for Soil Contamination of Agricultural Land. Ministry of Environmental Protection of China. Beijing. China). The concentrations of copper (Cu), zinc (Zn) and lead (Pb) were also above the national limits to a lesser extent. All eight heavy metals (Cd, Cu, Ni, Pb Zn, arsenic (As), chromium (Cr), and mercury (Hg)) exceeded the background values in the study area. The enrichment coefficients of rice, wheat and maize to Cd, Cu and Zn were higher than those to other elements. On the basis of Igeo, it can be indicated that the rhizosphere soil of rice was slightly polluted by Cd and Hg, while the concentrations of the other heavy metals were below the safety limits. The CF and pollution load index (PLI) indicated that the soil in the study area was heavily contaminated with heavy metals. A principal component analysis identified different sources of soil heavy metal pollution, that is, Cu, Pb, Zn and Cd from industrial sources, Cr and Ni from natural sources, and As and Hg from agricultural sources. The carcinogenic risk of heavy metals was related to the intake of crops. Residents in the study area ingest rice, wheat, and corn on a daily basis. On the basis this study, it is suggested that local governments should pay attention to the carcinogenic risk of heavy metals in rice.


Assuntos
Mercúrio , Metais Pesados , Oryza , Poluentes do Solo , Cádmio/análise , China , Produtos Agrícolas , Monitoramento Ambiental , Chumbo/análise , Mercúrio/análise , Metais Pesados/análise , Medição de Risco , Solo , Poluentes do Solo/análise , Zinco/análise
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