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1.
J Environ Manage ; 351: 119690, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38048707

RESUMO

Understanding the dynamics between public disaster assistance, disaster damages, and social vulnerability at county-level is crucial for designing effective disaster mitigation strategies. This study utilized the Local Bivariate Moran Index (LBMI) and geographically weighted regression (GWR) models to examine spatial patterns and relationships between disaster damages, social vulnerability, and public disaster assistance in contiguous US counties from 2001 to 2021. LBMI results reveal that public disaster assistance has predominantly been directed towards post-disaster recovery efforts, with a particular focus on coastal communities affected by major declared disasters. However, the distributions of public assistance and individual housing assistance, which are the two primary sources of public disaster assistance, do not adequately cover physically and socially vulnerable communities. The distribution of pre-disaster risk mitigation also falls short of sufficiently covering vulnerable communities. Results further indicate the complex interactions between different categories of natural disasters and public assistances. The GWR model results demonstrate spatial variations in predicting each category of public disaster assistance. These findings indicate the need to address disparities in accessing public disaster assistance in the US, and advocate for more equitable disaster mitigation strategies.


Assuntos
Desastres , Vulnerabilidade Social , Habitação , Assistência Pública
2.
Water Res ; 224: 119036, 2022 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-36115158

RESUMO

Deep insights into the receiving waters responses to optimal spatial allocation of LID-BMPs are considered extremely important. This study addressed the urgent need to incorporate receiving waters responses into the spatial allocation optimization of LID-BMPs and demonstrated the efficiency of the approach to guide watershed management. The integration of an overland-river coupling model and the NSGA-III algorithm resulted in the proposal of a general simulation-optimization framework for the optimal layout of LID-BMPs. The coupled model was swapped out for the surrogates to increase computational efficiency. When 40.71%, 36.06%, and 61.80% reductions in runoff volume, flood volume, and TP concentration are achieved, the newly proposed framework can save 34.44% and 16.31% cost compared to the approach that does not consider receiving waters responses and refined spatial allocation, respectively. Results indicate that the incorporation of receiving waters responses and refined spatial allocation are essential for the optimal design of LID-BMPs. This new framework offers the potential for more cost-effective high-cost solutions. The results of spatial optimization are significantly influenced by imperviousness.


Assuntos
Algoritmos , Rios , Simulação por Computador , Análise Custo-Benefício
3.
Gut Microbes ; 14(1): 2013764, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35025709

RESUMO

With the rapid development and high therapeutic efficiency and biosafety of gas-involving theranostics, hydrogen medicine has been particularly outstanding because hydrogen gas (H2), a microbial-derived gas, has potent anti-oxidative, anti-apoptotic, and anti-inflammatory activities in many disease models. Studies have suggested that H2-enriched saline/water alleviates colitis in murine models; however, the underlying mechanism remains poorly understood. Despite evidence demonstrating the importance of the microbial hydrogen economy, which reflects the balance between H2-producing (hydrogenogenic) and H2-utilizing (hydrogenotrophic) microbes in maintaining colonic mucosal ecosystems, minimal efforts have been exerted to manipulate relevant H2-microbe interactions for colonic health. Consistent with previous studies, we found that administration of hydrogen-rich saline (HS) ameliorated dextran sulfate sodium-induced acute colitis in a mouse model. Furthermore, we demonstrated that HS administration can increase the abundance of intestinal-specific short-chain fatty acid (SCFA)-producing bacteria and SCFA production, thereby activating the intracellular butyrate sensor peroxisome proliferator-activated receptor γ signaling and decreasing the epithelial expression of Nos2, consequently promoting the recovery of the colonic anaerobic environment. Our results also indicated that HS administration ameliorated disrupted intestinal barrier functions by modulating specific mucosa-associated mucolytic bacteria, leading to substantial inhibition of opportunistic pathogenic Escherichia coli expansion as well as a significant increase in the expression of interepithelial tight junction proteins and a decrease in intestinal barrier permeability in mice with colitis. Exogenous H2 reprograms colonocyte metabolism by regulating the H2-gut microbiota-SCFAs axis and strengthens the intestinal barrier by modulating specific mucosa-associated mucolytic bacteria, wherein improved microbial hydrogen economy alleviates colitis.


Assuntos
Bactérias/metabolismo , Colite/tratamento farmacológico , Colite/microbiologia , Microbioma Gastrointestinal , Hidrogênio/administração & dosagem , Mucosa Intestinal/efeitos dos fármacos , Animais , Bactérias/classificação , Bactérias/efeitos dos fármacos , Bactérias/genética , Colite/induzido quimicamente , Colite/metabolismo , Colo/efeitos dos fármacos , Colo/metabolismo , Colo/microbiologia , Sulfato de Dextrana/efeitos adversos , Ácidos Graxos Voláteis/metabolismo , Microbioma Gastrointestinal/efeitos dos fármacos , Humanos , Hidrogênio/metabolismo , Mucosa Intestinal/metabolismo , Mucosa Intestinal/microbiologia , Masculino , Camundongos , Camundongos Endogâmicos C57BL
4.
J Environ Manage ; 304: 114230, 2022 Feb 15.
Artigo em Inglês | MEDLINE | ID: mdl-34883437

RESUMO

This study conducts a life cycle environmental and economic quantification comparison of urban runoff source control facilities (URSCFs) through construction and operation stages in two urban functional regions (i.e., residential area and campus). From the environmental perspective, URSCFs construction in residential area has both higher environmental impacts and benefits than that in campus. The operation stage of URSCFs can observe significant benefit for both residential area and campus. We then develop a set of monetized method to make a comprehensive benefit evaluation (i.e., environmental, economic, and social benefit) of URSCFs. Overall, the two areas have payback time less than thirteen years for their investment which is acceptable when compared with the assumed total service period (30 years). Specifically, the payback time of campus is 5.62 years and residential area is 12.44 years. This implies that the campus has great potential to achieve high cost-benefit ratio and thus the Sponge City construction in campus can implement URSCFs with less engineering and material consumption due to its more spacious site than residential area with high building density. For both residential area and campus, permeable pavement has the highest environmental impact and economic cost because of the concrete consumption. Thus, we recommend that it should be cautious of the construction of concrete permeable pavement and find environmentally and economically alternatives in future URSCFs projects.


Assuntos
Meio Ambiente , Poluição Ambiental/prevenção & controle , Cidades , Análise Custo-Benefício , Poluição Ambiental/economia
5.
Waste Manag ; 33(9): 1843-52, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23777667

RESUMO

A life cycle assessment was conducted to evaluate the environmental and economic effects of sewage sludge co-incineration in a coal-fired power plant. The general approach employed by a coal-fired power plant was also assessed as control. Sewage sludge co-incineration technology causes greater environmental burden than does coal-based energy production technology because of the additional electricity consumption and wastewater treatment required for the pretreatment of sewage sludge, direct emissions from sludge incineration, and incinerated ash disposal processes. However, sewage sludge co-incineration presents higher economic benefits because of electricity subsidies and the income generating potential of sludge. Environmental assessment results indicate that sewage sludge co-incineration is unsuitable for mitigating the increasing pressure brought on by sewage sludge pollution. Reducing the overall environmental effect of sludge co-incineration power stations necessitates increasing net coal consumption efficiency, incinerated ash reuse rate, dedust system efficiency, and sludge water content rate.


Assuntos
Carvão Mineral , Incineração/métodos , Esgotos , China , Análise Custo-Benefício , Meio Ambiente , Incineração/economia , Eliminação de Resíduos , Resíduos Sólidos , Água
6.
JBI Libr Syst Rev ; 10(9): 513-573, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-27820546

RESUMO

BACKGROUND: Patient fall is among the top five sentinel events in hospitals due to the resultant functional loss and injury sustained. Precise fall risk assessment and prevention strategies are important components of a fall prevention program. Due to psychiatric conditions and medications, these patients may require a different fall management program compared to other patient populations. OBJECTIVE: The objective of this review was to identify the best available evidence for the effectiveness of nursing fall risk assessment tools, interventions to reduce incidence of falls, and common risk factors of adult psychiatric patients who fall. INCLUSION CRITERIA: Adults (19 to 64 years) diagnosed with mental illnessEvaluation of nursing fall risk assessment tools in adult psychiatric settings, and interventions, which minimised fall risk or fall rates.Number of patient falls during hospitalisation was the main outcome.Primary quantitative studies published in English language. SEARCH STRATEGY: The literature search sought published studies, and was limited to English language reports. There were no date restrictions applied to the search. Electronic databases searched included:CINAHLPubMedCochrane Central Register of Controlled TrialsPsycINFOScienceDirectScopusWeb of ScienceWiley-InterScienceProQuestMedNar METHODOLOGICAL QUALITY: Studies retrieved were assessed by two independent reviewers for methodological validity prior to inclusion in the review using standardised critical appraisal instruments from the Joanna Briggs Institute System for the Unified Management, Assessment and Review of Information (JBI-SUMARI). DATA EXTRACTION: Data including specific details about the methods, settings, purposes, populations, interventions, and outcomes significant to the review's objectives were extracted by two independent reviewers using standardised data extraction tools from JBI-SUMARI. RESULTS: Eleven studies were included in this review: three before-and-after studies, four descriptive studies, two case control studies and two cohort studies. Evidence with regards to the effectiveness of fall risk assessment tools and prevention strategies was inconclusive. Certain risk factors which were more frequently associated with falls included diagnoses of depression, bipolar disorder, and dementia / Alzheimer's disease, altered mental status, physiological symptoms, past history of falls, mobility and gait problems, concurrent medical conditions, polypharmacy, and taking of certain medications such as sedatives, antidepressants and mood stabilisers, particularly lithium. CONCLUSION: Evidence on the effectiveness of fall risk assessment tools and prevention strategies in psychiatric setting was inconclusive due to a paucity of studies. However, certain risk factors were found to be more commonly associated with falls in adult psychiatric patients (Level III Evidence).Constant observation of the side effects of medications, particularly orthostatic hypotension, and review of patients' medical profile by doctors or pharmacists may be helpful in preventing falls in psychiatric patients. Findings on common risk factors can better aid healthcare professionals in identifying psychiatric patients who are at risk for falls.More research is needed on the evaluation of fall risk assessment tools and fall prevention strategies, specifically for the adult psychiatric patients. More prospective and better quality studies examining fall risk factors in psychiatric patients are needed.

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