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1.
Ecotoxicol Environ Saf ; 273: 116117, 2024 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-38377780

RESUMO

Field rapid determination of soil accessible Cr(Ⅵ) is of great significance for on-site assessment and decision-making about the health risks of contaminated sites. When the thickness of solutions with various concentrations of Cr(Ⅵ) is constant, there would be a quantitative relationship between the chromogenic difference of Cr(Ⅵ) solutions and the concentration of Cr(Ⅵ). The chromogenic difference could be described by Red (R), Green (G), Blue (B) values. Based on the chromogenic reaction between 1,5-diphenylcarbazide and Cr(Ⅵ), this study first established the calibration curve between the chromogenic difference and the concentration of Cr(Ⅵ) in standard solution with or without 0.01 M CaCl2, using an RGB color sensor. This is the subsequent determination basis of the method for rapidly assessing accessible Cr(Ⅵ) in the field (M-RGB). Then, the concentration of accessible Cr(Ⅵ) of contaminated soil with "hand-shaking + standing" field extraction method was compared with "end-over-end shaking" laboratory extraction method. Finally, the accessible Cr(Ⅵ) of contaminated soil extractants was determined via M-RGB integrating the field extraction method. Results indicated there was a highly significant linear relationship between colorimetric difference value (∆E) and Cr(Ⅵ) concentration in the range of 0.1-3 mg/L (R2 > 0.99, P < 0.01), based on the Euclidean formula for calculating ∆E. The "hand-shaking + standing" field extraction method was effective in obtaining accessible Cr(Ⅵ) extractants with or without 0.01 M CaCl2, with the high extraction efficiency within 100±1%. The concentrations of accessible Cr(Ⅵ) in various polluted soils determined by M-RGB were consistent with that determined by the ultraviolet-visible spectrophotometry, with the relative error within ±5%, and the relative standard deviation ≤ 20%. The spiked recovery experiments showed that the recovery of M-RGB was between 95% and 105%, which means M-RGB could realize the trace analysis for accessible Cr(Ⅵ) in the field.


Assuntos
Cromo , Solo , Cloreto de Cálcio , Cromo/análise , Poluição Ambiental/análise
2.
Environ Pollut ; 344: 123348, 2024 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-38219896

RESUMO

Field rapid determination of soil accessible Cu(Ⅱ) was important for environmental safety and human health risk assessment. In this study, an inexpensive red, green, and blue (RGB) color sensor was used for quantitative color difference analysis of the colored solution for soil accessible Cu(Ⅱ) with bis-cyclohexanone oxalydihydrazone as color reagent to develop a new method for analyzing soil accessible under field conditions. First, the calibration curve for RGB color sensor method was established in the standard solutions of Cu(II). Then the "hand shaking + standing" field extraction method for accessible Cu(Ⅱ) was developed. Finally, the method was applied in contaminated soils in the laboratory and in the field, and set the values determined by atomic absorption spectroscopy (AAS) as the standard ones. Results indicated that in the range of 0.1-5 mg L-1 Cu(II), the RGB Euclidean chromogenic difference values were directly linear correlated with the concentration of Cu(II) (R2 > 0.999). The interference of Fe(Ⅲ) and Mn(Ⅱ) could be eliminated by adding citric acid. The "hand shaking + standing" field extraction method could effectively extract the accessible Cu(Ⅱ) from soil with the high extraction rates. The concentrations of accessible Cu(II) in various polluted soils determined by RGB color sensor method were consistent with that determined by AAS, with the relative error within ±5%, the relative standard deviation ≤ 20%. The recovery of Cu(II) in RGB color sensor method was between 97% and 105%, which could meet the requirements of trace analysis of accessible Cu(Ⅱ) in the field. The high accuracy and precision of RGB color sensor method was reconfirmed in the rapid field quantitative assessment of soil accessible Cu(Ⅱ). Due to that the RGB color sensor was low cost, rechargeable, portable, mobile, ambient light resistant, the method would have a great potential for the determination of accessible Cu(Ⅱ) in contaminated soils.


Assuntos
Compostos Férricos , Solo , Humanos , Solo/química , Espectrofotometria Atômica
3.
Artigo em Inglês | MEDLINE | ID: mdl-36341280

RESUMO

Objective: Real-time monitoring of nanoparticle delivery in biological models is essential to optimize nanoparticle-mediated therapies. However, few techniques are available for convenient real-time monitoring of nanoparticle concentrations in tissue samples. This work reported novel optical spectroscopic approaches for low-cost point-of-care real-time quantification of nanoparticle concentrations in biological tissue samples. Methods: Fiber probe measured diffuse reflectance can be described with a simple analytical model by introducing an explicit dependence on the reduced scattering coefficient. Relying on this, the changes on the inverse of diffuse reflectance are proportional to absorption change when the scattering perturbation is negligible. We developed this model with proper wavelength pairs and implemented it with both a standard optical spectroscopy platform and a low-cost compact spectroscopy device for near real-time quantification of nanoparticle concentrations in biological tissue models. Results: Both tissue-mimicking phantom and ex vivo tissue sample studies showed that our optical spectroscopic techniques could quantify nanoparticle concentrations in near real-time with high accuracies (less than 5% error) using only a pair of narrow wavelengths (530 nm and 630 nm). Conclusion: Novel low-cost point-of-care optical spectroscopic techniques were demonstrated for rapid accurate quantification of nanoparticle concentrations in tissue-mimicking medium and ex vivo tissue samples using optical signals measured at a pair of narrow wavelengths. Significance: Our methods will potentially facilitate real-time monitoring of nanoparticle delivery in biological models using low-cost point-of-care optical spectroscopy platforms, which will significantly advance nanomedicine in cancer research.

4.
Br J Soc Psychol ; 62(2): 725-742, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-36266767

RESUMO

Previous research suggests that receiving a charity donation could induce gratitude but threaten self-esteem. We investigated if peer charity donations from typical children benefit or harm the mental health of their left-behind children (LBC) classmates. We recruited children at a school (i.e., intervened school) that organized peer charity donations every semester and three typical schools (i.e., non-intervened school) without such intervention in China. Participants completed the gratitude, self-esteem, depression, and social anxiety scales. A statistical toolbox, "Matchit", randomly selected 420 children aged 9-13 (220 females, 200 males, 213 LBC, 207 non-LBC); there was no significant difference in left-behind status, age, gender, or family economic status (all p > .10) between the intervened and non-intervened groups (210 per group). Structural equation model analyses revealed that gratitude was associated with higher self-esteem, lower social anxiety, and lower depression. Moreover, the intervention effect on self-esteem was significantly positive among the LBC recipients and non-LBC donors. The interaction between intervention and left-behind status was significant on gratitude and depression. Specifically, the intervention effect was not significant on gratitude or depression among the LBC but was significantly negative on gratitude and depression among the non-LBC. Peer charity donation may increase self-esteem among children (recipients or donors) via increased social connection or satisfaction of basic needs, yet decreased gratitude among the donors due to the "moral licensing effect".


Assuntos
Instituições de Caridade , Estudantes , Masculino , Feminino , Humanos , Criança , Fatores Socioeconômicos , Autoimagem , China
5.
J Environ Sci (China) ; 124: 513-521, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36182160

RESUMO

Over the past decade, the emission standards and fuel standards in Beijing have been upgraded twice, and the vehicle structure has been improved by accelerating the elimination of 2.95 million old vehicles. Through the formulation and implementation of these policies, the emissions of carbon monoxide (CO), volatile organic compounds (VOCs), nitrogen oxides (NOx), and fine particulate matter (PM2.5) in 2019 were 147.9, 25.3, 43.4, and 0.91 kton in Beijing, respectively. The emission factor method was adopted to better understand the emissions characteristics of primary air pollutants from combustion engine vehicles and to improve pollution control. In combination with the air quality improvement goals and the status of social and economic development during the 14th Five-Year Plan period in Beijing, different vehicle pollution control scenarios were established, and emissions reductions were projected. The results show that the emissions of four air pollutants (CO, VOCs, NOx, and PM2.5) from vehicles in Beijing decreased by an average of 68% in 2019, compared to their levels in 2009. The contribution of NOx emissions from diesel vehicles increased from 35% in 2009 to 56% in 2019, which indicated that clean and energy-saving diesel vehicle fleets should be further improved. Electric vehicle adoption could be an important measure to reduce pollutant emissions. With the further upgrading of vehicle structure and the adoption of electric vehicles, it is expected that the total emissions of the four vehicle pollutants can be reduced by 20%-41% by the end of the 14th Five-Year Plan period.


Assuntos
Poluentes Atmosféricos , Poluição do Ar , Compostos Orgânicos Voláteis , Poluentes Atmosféricos/análise , Poluição do Ar/análise , Pequim , Monóxido de Carbono/análise , China , Monitoramento Ambiental , Óxidos de Nitrogênio/análise , Material Particulado/análise , Emissões de Veículos/análise , Compostos Orgânicos Voláteis/análise
6.
Brain Struct Funct ; 227(8): 2751-2767, 2022 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-36112232

RESUMO

Regret affects decision-making behavior, which is mediated by a cognitive process known as counterfactual thinking in economic science. Several studies indicate that orbitofrontal cortex (OFC) plays a crucial role in decision-making behavior. However, the neural correlates of regret trait and the function of the OFC in decision-making remain unclear. In this study, we employed a typical monetary decision-making task, a modified 'Wheel of Fortune gamble' paradigm, to investigate decision-making behavior and its neural mechanism. We combined voxel-based morphometry (VBM) and task-evoked functional magnetic resonance imaging (fMRI) analyses to explore the neural substrates of regret trait. VBM analyses revealed that individual Regret Scale Score was negatively associated with the gray-matter volume (GMV) in the frontal and temporal areas, including the bilateral OFC. These results indicate that individuals with high regret trait have smaller GMV in these areas. Moreover, we found stronger task-evoked activation of the left OFC in high regret trait individuals during the decision-maker's choice (choose conditions) phase, whereas we did not find this relationship in computer-selected's (follow conditions) choice phase. Using generalized psychophysiological interactions (PPI) analysis, we further found that the functional connectivity of the left OFC to right inferior frontal gyrus and left cerebellum was stronger in the complete feedback choose condition (under regret theoretical framework) than partial feedback choose condition (under disappointment theoretical framework). These findings verify the critical role of the OFC in the decision-making, more importantly, provide novel insights into the morphological and functional substrates of individual regret trait.


Assuntos
Emoções , Córtex Pré-Frontal , Humanos , Córtex Pré-Frontal/patologia , Emoções/fisiologia , Substância Cinzenta , Lobo Frontal/anatomia & histologia , Imageamento por Ressonância Magnética , Tomada de Decisões/fisiologia
7.
Huan Jing Ke Xue ; 43(9): 4587-4596, 2022 Sep 08.
Artigo em Chinês | MEDLINE | ID: mdl-36096599

RESUMO

Green roofs are regarded as one of the important measures for the sponge city construction. However, the comprehensive impacts of configuration factors (e.g., vegetation and substrates) on runoff quality from green roofs are not clear, which limits the promotion of green roofs. In this study, 12 green roofs with three vegetation types (i.e., Sedum lineare, Portulaca grandiflora, and non-vegetated substrates), three substrate types (i.e., local planting soil, engineered soil, and light growing medium), and two substrate depths (i.e., 10 cm and 15 cm) were set up in Beijing. During the rainy season of 2019, the rainfall characteristics, runoff volumes, and concentrations of nutrients and heavy metals of runoff from the green roofs were monitored. Based on the measured data, a runoff quality index (RQI) was developed to evaluate the comprehensive influences of configurations on runoff quality of the green roofs. The results showed that vegetation could improve runoff reduction rate and decrease the concentrations of NO3--N in runoff of green roofs. The RQIs of green roofs planted with S. linear and P. grandiflora were similar, and the evaluation results of runoff quality were better than those with non-vegetated substrates. The materials of substrates had significant influences on the runoff reduction rate and pollutant concentrations in runoff from green roofs. The green roofs with light growing medium, which had the lowest runoff reduction rates and the highest concentrations of NH4+-N, DFe, DMn, and DZn in the runoff, showed poorer runoff quality than the green roofs with local planting soil and engineered soil. The green roofs with a substrate depth of 15 cm had higher runoff reduction rates than those with 10 cm deep substrate, and the runoff quality was better than those with a substrate depth of 10 cm. The results of this study provide scientific reference for the design and integrated assessment of green roofs.


Assuntos
Metais Pesados , Sedum , Conservação dos Recursos Naturais/métodos , Plantas , Chuva , Solo
8.
Artigo em Inglês | MEDLINE | ID: mdl-35457322

RESUMO

The arctic region is a remote area with relatively few anthropogenic inputs, but there is increasing concern over toxic trace metal contamination in the Arctic Ocean. In this study, distribution characteristics of eight trace metals in the surface sediment of the Pacific Sector of the Arctic Ocean and Bering Strait are analyzed. The geochemical baseline value of each metal element is explored using the relative cumulative frequency curve method; the enrichment factor (EF), geo-accumulation index (Igeo) and potential ecological risk index (RI) are applied to assess the ecological risk level of the trace metals. According to the results, Cu, As and Hg had a little more content variation, and their contents in some areas were significantly higher than the previous reports. EF values show an obvious enrichment of element As, followed by Cr element with the moderate enrichment; the enrichment of the other six elements are not related to human activity. The Igeo value shows a moderately contaminated to heavily contaminated level of As and a moderately contaminated level of Cr. According to the potential ecological risk indexes in each site, most sites are at a low ecological risk level except five sites with RI/baseline values exceeding 150 which are at a moderate ecological risk level.


Assuntos
Metais Pesados , Oligoelementos , Poluentes Químicos da Água , China , Monitoramento Ambiental/métodos , Sedimentos Geológicos/química , Humanos , Metais Pesados/análise , Medição de Risco , Oligoelementos/análise , Poluentes Químicos da Água/análise
9.
Brain Commun ; 4(2): fcac046, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35415604

RESUMO

For patients with glioma located in or adjacent to the linguistic eloquent cortex, awake surgery with an emphasis on the preservation of language function is preferred. However, the brain network basis of postoperative linguistic functional outcomes remains largely unknown. In this work, 34 patients with left cerebral gliomas who underwent awake surgery were assessed for language function and resting-state network properties before and after surgery. We found that there were 28 patients whose language function returned to at least 80% of the baseline scores within 3 months after surgery or to 85% within 6 months after surgery. For these patients, the spontaneous recovery of language function synchronized with changes within the language and cognitive control networks, but not with other networks. Specifically, compared with baseline values, language functions and global network properties were the worst within 1 month after surgery and gradually recovered within 6 months after surgery. The recovery of connections was tumour location dependent and was attributed to both ipsihemispheric and interhemispheric connections. In contrast, for six patients whose language function did not recover well, severe network disruptions were observed before surgery and persisted into the chronic phase. This study suggests the synchronization of functional network normalization and spontaneous language recovery in postoperative patients with glioma.

10.
Int J Pediatr Otorhinolaryngol ; 150: 110901, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-34450546

RESUMO

OBJECTIVE: To explore the relationship between obstructive sleep apnea (OSA) and cognitive impairment by combining event-related evoked potentials (ERPs) and China-Wechsler Younger Children Scale (C-WISC) in children with sleep-disordered breathing (SDB) with vs. without OSA. METHODS: This was a retrospective case-control study of all consecutive children (n = 148) with adenoid tonsil hypertrophy between July 2017 and March 2019 at the Hospital. RESULTS: The children were divided into the OSA (n = 102) and non-OSA (n = 46) groups. The apnea-hypopnea index (AHI), obstructive apnea index (OAI), and obstructive apnea-hypopnea index (OAHI) in the OSA group were elevated compared with those of the non-OSA group (all P < 0.001). The mean oxygen saturation (SaO2) and SaO2 nadir were lower in the OSA group compared with the non-OSA group (both P < 0.001). The respiratory arousal index (RAI) values in the OSA group were larger than those of the non-OSA group (P < 0.001). The P300 and N100 latencies in the OSA group were longer than those of the non-OSA group (both P < 0.001). Pearson's correlation analysis revealed correlations of the P300 peak latency with full-scale intelligence quotient (FIQ) (P < 0.001 and r = -0.527), verbal intelligence quotient (VIQ) (P < 0.001 and r = -0.448), and performance intelligence quotient (PIQ) (P < 0.001 and r = -0.515). There was a correlation between the N100 peak latency and PIQ (P = 0.026 and r = -0.183). CONCLUSION: ERPs, as an objective measurement, might help assess cognitive impairment in children with OSA.


Assuntos
Disfunção Cognitiva , Apneia Obstrutiva do Sono , Estudos de Casos e Controles , Criança , China , Disfunção Cognitiva/diagnóstico , Disfunção Cognitiva/etiologia , Potenciais Evocados , Humanos , Polissonografia , Estudos Retrospectivos , Apneia Obstrutiva do Sono/complicações , Apneia Obstrutiva do Sono/diagnóstico , Escalas de Wechsler
11.
Environ Geochem Health ; 42(3): 745-767, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30761418

RESUMO

The questions of how to mitigate climate change and its impact on human health are currently high on the Chinese agenda for future development. The emission trading scheme (ETS) has become one of China's most important instruments to address climate change through a market mechanism. In the wake of the evolution from regional pilots to a nationwide scheme, it is inevitable to be confronted with tremendous political-economic-institutional challenges. To facilitate a smooth start-up of the upcoming nationwide ETS, this study provides a systematic overview of seven ETS pilots, involving the detailed comparison of ETS design and the in-depth evaluation of market performance, both internal and external performance, based on trading data. Then, the achievements and deficiencies of seven ETS pilots are summarized, several challenges for the current time are discussed, and policy proposals for China's national-level ETS are navigated further coupled with international experience. This study finds that China's ETS pilots, from the short-term perspective, are successful, especially in the reinforcement of China's capacity to develop a market-based scheme in an economy that still cherishes many non-market endowments. However, deficiencies lie in both the internal and external market performance, such as the carbon price lacking a signal function, insufficient incentives for compliance, too low market liquidity, and much too high market fragmentation. Moreover, the retrospective examination of China's ETS pilots suggests that a nationwide ETS should at least be based on an extension of the cap duration from single year to several years, uniform rules on monitoring/reporting/verification and allowance allocation, and the improvement of institutional foundation.


Assuntos
Carbono/economia , Mudança Climática , Política Ambiental/economia , Gases de Efeito Estufa/economia , China , Custos e Análise de Custo , Projetos Piloto , Estudos Retrospectivos
12.
Data Brief ; 18: 69-75, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-29896493

RESUMO

The data presented herein are related to the research article entitled "Magnesium isoglycyrrhizinate blocks fructose-induced hepatic NF-κB/NLRP3 inflammasome activation and lipid metabolism disorder" (Zhao et al., 2017) [1]. This article describes the effects of magnesium isoglycyrrhizinate on 24-h food or water intake in fructose-fed rats at 15-week. In addition, this article expands the effect of magnesium isoglycyrrhizinate on the animal body weight change during 1-17 week. The field dataset is made publicly available to enable critical or extended analyzes.

13.
J Comp Eff Res ; 7(8): 785-795, 2018 08.
Artigo em Inglês | MEDLINE | ID: mdl-29860879

RESUMO

Aim: To evaluate the cost-effectiveness of the novel all-oral direct-acting antiviral regimen daclatasvir + asunaprevir (DUAL), versus interferon-based regimens for the treatment of chronic hepatitis C virus genotype 1b infection. Methods: Inputs for a lifetime Markov model were sourced from clinical trials and published literature. Outputs include disease management costs, life expectancy, quality-adjusted life-years and cost-effectiveness. Sensitivity analyses assessed the drivers of cost-effectiveness and sustained virologic response thresholds at which DUAL is cost-saving. Results: DUAL was associated with discounted incremental quality-adjusted life-years of 1.29-3.85 and incremental life-years of 0.85-2.59 per patient, with discounted lifetime cost savings of USD$1415-8525. Associated sustained virologic response rates could fall to 45.1-84.8%, while remaining dominant. Conclusion: Treatment with DUAL provides significant clinical benefit, while accruing lower lifetime costs.


Assuntos
Antivirais/uso terapêutico , Hepatite C Crônica/tratamento farmacológico , Imidazóis/uso terapêutico , Isoquinolinas/uso terapêutico , Sulfonamidas/uso terapêutico , Antivirais/administração & dosagem , Antivirais/economia , Carbamatos , China , Análise Custo-Benefício , Quimioterapia Combinada , Genótipo , Gastos em Saúde , Recursos em Saúde/economia , Recursos em Saúde/estatística & dados numéricos , Humanos , Imidazóis/administração & dosagem , Imidazóis/economia , Isoquinolinas/administração & dosagem , Isoquinolinas/economia , Expectativa de Vida , Masculino , Cadeias de Markov , Modelos Econométricos , Pirrolidinas , Anos de Vida Ajustados por Qualidade de Vida , Sulfonamidas/administração & dosagem , Sulfonamidas/economia , Valina/análogos & derivados
15.
Aging Med (Milton) ; 1(2): 100-105, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31942485

RESUMO

Comprehensive geriatric assessment is the major approach in screening geriatric syndrome. The aim of this expert consensus is to supply standard operating procedures for clinical practice of comprehensive geriatric assessment in China.

16.
Environ Sci Pollut Res Int ; 25(10): 9311-9320, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-29249034

RESUMO

We examined per- and polyfluoroalkyl substances (PFASs) in air from eight cities, and in water from six drinking-water treatment plants (DWTPs), in central eastern China. We analyzed raw and treated water samples from the DWTPs for 17 ionic PFASs with high-performance liquid chromatography/negative-electrospray-ionization tandem mass spectrometry (HPLC/(-)ESI-MS/MS), and analyzed the gas and particle phases of atmospheric samples for 12 neutral PFASs by gas chromatography-mass spectrometry (GC-MS). Perfluorooctanoic acid (PFOA) and perfluorohexanoic acid (PFHxA) were the dominant compounds in drinking water, and fluorotelomer alcohols (FTOHs) dominated in atmospheric samples. Of all the compounds in the treated water samples, the concentration of PFOA, at 51.0 ng L-1, was the highest. Conventional treatments such as coagulation (COA), flocculation (FOC), sedimentation (SED), and sand filtration (SAF) did not remove PFASs. Advanced treatments, however, including ultrafiltration (UF) and activated carbon (AC), removed the majority of PFASs except for shorter-chain PFASs such as perfluorobutanoic acid (PFBA) and perfluoropentanoic acid (PFPA). We also investigated human exposure to PFASs via drinking water and the atmosphere and found that the mean daily intake of PFASs was 0.43 ng kg-1 day-1.


Assuntos
Atmosfera/análise , Caproatos/química , Caprilatos/química , Água Potável/química , Fluorocarbonos/análise , Caproatos/análise , China , Cromatografia Líquida de Alta Pressão , Cidades , Fluorocarbonos/química , Humanos , Medição de Risco , Espectrometria de Massas em Tandem
17.
Biomed Environ Sci ; 30(10): 737-748, 2017 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-29122094

RESUMO

OBJECTIVE: To investigate the status of folic acid (FA) supplementation and determinants of its use in pregnant Chinese women. METHODS: In this cross-sectional study, questionnaires were used to collect information of participants and FA supplementation. Women were recruited between 6 and 12 weeks postpartum in Tianjin, China, between July 2015 and July 2016. RESULTS: A total of 1,921 women were recruited in the study. Approximately 93.1% of the study participants used FA, while 14.4% of the women taking FA from three months prior to preconception to three months post-conception. Women who took FA for three months prior to preconception through at least three months into their pregnancy were more likely to be between 30 and 34 years old (OR = 2.91, 95% CI: 1.15, 7.33), employed (OR = 2.07, 95% CI: 1.17, 3.67), primigravida (OR = 5.20, 95% CI: 3.02, 8.96), married to spouses with an intermediate education level (OR = 2.92, 95% CI: 1.45, 5.89), and earn a high family income (OR = 3.19, 95% CI: 1.57, 6.49). CONCLUSION: The prevalence of periconceptional FA intake was far below the requirements of the National Health and Family Planning Commission of China; therefore, knowledge of FA supplementation should be strengthened among women who are or planning to become pregnant.


Assuntos
Suplementos Nutricionais , Ácido Fólico/administração & dosagem , Vitaminas/administração & dosagem , Adolescente , Adulto , China , Estudos Transversais , Coleta de Dados , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Defeitos do Tubo Neural , Gravidez , Fatores Socioeconômicos , Inquéritos e Questionários , Adulto Jovem
18.
Chin Med J (Engl) ; 130(20): 2447-2452, 2017 Oct 20.
Artigo em Inglês | MEDLINE | ID: mdl-29052566

RESUMO

BACKGROUND: Renal cell carcinoma (RCC) is the most common type of malignant renal tumors with a growing incidence in the recent years. This study aimed to investigate the influencing factors and variation trend of hospitalization expenditures among RCC patients in a single-centered hospital in Beijing during 5 consecutive years and to find the major cost items and fluctuation tendency of inpatient medical expenditures. METHODS: The information of medical expenditures among RCC patients in a Grade-A tertiary hospital during the years 2012-2016 was investigated to find the main cost items and changes affecting the medical cost structure. Gray correlation method was adopted in quantitative analysis to analyze the composition of medical expenditures, and the variation of hospitalization expense structure during the five years was studied by analyzing the degree of structural variation. RESULTS: The cost item constitution of the hospitalization expenditures among RCC patients was relatively stable in the sample hospital during the past five years. To be specific, drug costs accounted for the largest proportion of medical expenditures each year, with the highest of 37.81% in 2012, and showed a slowly declining tendency in the coming years. The cost item with the highest correlation degree was drug costs, with the value of 1.0000; followed by the costs of surgeries, 0.8423. Furthermore, drug costs shared the largest proportion (40.95%) of structural variation, followed by the costs of surgeries (18.35%). CONCLUSIONS: Drug costs are the major influencing factors of the hospitalization expenditures among RCC patients. Thus, reasonable control on excessive drugs as well as the standardization of the diagnosis and treatment behaviors is conducive in reducing medical expenditures as well as easing patients' economic burdens. Besides, the positive growth on surgery costs suggests that the labor value of medical staffs has been gradually recognized.


Assuntos
Carcinoma de Células Renais/economia , Gastos em Saúde/estatística & dados numéricos , Hospitalização/economia , Neoplasias Renais/economia , Idoso , Feminino , Hospitalização/estatística & dados numéricos , Humanos , Masculino , Pessoa de Meia-Idade , Centros de Atenção Terciária/economia , Centros de Atenção Terciária/estatística & dados numéricos
19.
Artigo em Inglês | MEDLINE | ID: mdl-27123191

RESUMO

OBJECTIVES: In 2009, the Chinese government launched a national healthcare reform programme aiming to control healthcare expenditure and increase the quality of care. As part of this programme, a new drug pricing reform was initiated on 1 June 2015. The objective of this study was to describe the changing landscape of drug pricing policy in China and analyse the potential impact of the reform. METHODS: The authors conducted thorough research on the drug pricing reform using three Chinese databases (CNKI, Wanfang, and Weipu), Chinese health authority websites, relevant press releases, and pharmaceutical blogs and discussion forums. This research was complemented with qualitative research based on targeted interviews with key Chinese opinion leaders representing the authorities' and prescribers' perspectives. RESULTS: With the current reform, the government has attempted to replace its direct control over the prices of reimbursable drugs with indirect, incentive-driven influence. Although the exact implementation of the reform remains unclear at the moment, the changes introduced so far and the pilot project designs indicate that China is considering adaptation of some form of internal and external reference pricing policies, commonly used in the Organisation for Economic Co-operation and Development countries. Several challenges related to the potential new mechanism were identified: 1) the risk of hospital underfunding, if hospital funding reform is not prioritised; 2) the risk of promoting the use of cheap, low-quality drugs, if a reliable quality control system is not in place and discrepancy between the available drugs is present; 3) the risk of increasing disparity in access to care between poor and rich regions, in case of country-wide price convergence; and 4) the risk of industry underinvestment, resulting in reduced competition, issues with quality and sustainability of supply, and potentially negative social impact. CONCLUSIONS: Foreign pricing policies cannot be transferred to China without prioritising historical, cultural, and economic contextualisation. Otherwise, the new policy may be counterproductive and affect the whole healthcare chain, as well as the health outcomes of Chinese patients.

20.
Huan Jing Ke Xue ; 37(1): 88-93, 2016 Jan 15.
Artigo em Chinês | MEDLINE | ID: mdl-27078945

RESUMO

With the economic development and population growth in Beijing, there is a strong need for construction and housing, which leads to the increase of the construction areas. Meanwhile, as a local provided material, the production of concrete has been raised. In the process of concrete production by concrete batching, there are numerous particulates emitted, which have large effect on the atmospheric environment, however, systematic study about the tempo-spatial characteristics of pollutant emission from concrete batching is still rare. In this study, we estimated the emission of particulates from concrete batching from 1991 to 2012 using emission factor method, analyzed the tempo-spatial characteristics of pollutant emission, established the uncertainty range by adopting Monte-Carlo method, and predicted the future emission in 2020 based on the relative environmental and economical policies. The results showed that: (1) the emissions of particulates from concrete batching showed a trend of "first increase and then decrease", reaching the maximum in 2005, and then decreased due to stricter emission standard and enhanced environmental management. (2) according to spatial distribution, the emission of particulates from concrete batch mainly concentrated in the urban area with more human activities, and the area between the fifth ring and the sixth ring contributed the most. (3) through scenarios analysis, for further reducing the emission from concrete batching in 2020, more stricter standard for green production as well as powerful supervision is needed.


Assuntos
Poluentes Atmosféricos/análise , Materiais de Construção , Material Particulado/análise , Pequim , Atividades Humanas , Humanos
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