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1.
J Environ Manage ; 354: 120485, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38422572

RESUMO

Climate change is a non-traditional security crisis affecting the global economy and diplomatic progress. In order to curtail carbon emissions and alleviate the perils of climate change at their roots, urban green innovation (UGI) has emerged as a pivotal technological solution. Using the expansion of the Yangtze River Delta urban agglomeration in China as a case study, this paper develops a quasi-experimental model to analyze the effects of regional integration policies on UGI. The main findings are: (1) Regional integration policies significantly enhance UGI and their impact is more pronounced with the expansion of urban agglomerations; (2) Regional integration policies contribute to the advancement of exploitative green innovation while tending to diminish exploratory green innovation; (3) The green innovation effects (GIEs) created by the expansion of regional integration policies are largely influenced by governmental mechanisms on environmental governance as well as residents' green preferences. Based on these findings, recommendations are put forward to promote UGI from the perspective of policy implementation.


Assuntos
Conservação dos Recursos Naturais , Política Ambiental , Carbono , China , Políticas , Rios , Cidades , Desenvolvimento Econômico
2.
Heliyon ; 9(6): e17440, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-37426792

RESUMO

Understanding spatial change and its driving factors behind coastal development is essential for coastal management and restoration. There is an urgent need for quantitative assessments of sustainable development in the coastal ecosystems that are most affected by anthropogenic activities and climate change. This study built a theme-based evaluation methodology with the Natural-Economic-Social (NES) complex ecosystem and proposed an evaluation system of coastal sustainable development (CSD) to understand the complex interactions between coastal ecosystems and anthropogenic activities. The approach revealed the levels of coastal natural, economic, and social sustainable development in the countries along the Maritime Silk Road (MSR) from 2010 to 2020. The results showed (1) a decreasing trend for coastal sustainable development between 2010 and 2015 and a rapid increasing trend between 2015 and 2020; (2) spatially varied CSD, with higher levels in Europe and Southeast Asia and lower levels in South and West Asia and North Africa; and (3) a strong influence on CSD by a combination of economic and social factors and relatively little influence by natural factors. The study further assessed the natural, economic, and social development scores for 41 countries and compared them with the mean scores (MSR) to classify coastal development patterns into three stages (favorable, transitional, and unfavorable). Finally, in the context of the 2030 Agenda for Sustainable Development, the study highlighted the importance of more refined global indicators for CSD assessments.

3.
Environ Sci Pollut Res Int ; 30(1): 557-577, 2023 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-35902524

RESUMO

Construction waste (CW) source reduction is a crucial strategy to address the sustainability issue of the construction industry. The economic benefit is a key factor affecting project decision-makers on whether to implement this strategy. However, limited studies analysed the cost-benefit of CW source reduction from a system dynamic perspective. Therefore, by considering the design and construction phase as a whole, this study constructed a system dynamics (SD) model based on the identification of the factors affecting the cost-benefit of CW source reduction to analyse the cost-benefit of CW source reduction. A residential building project in China's Chengdu was used for the study case. The results show that the net benefit of CW source reduction is positive, and BIM implementation, design for standard material size, and building material storage are the three strategies to effectively improve the economic benefits of CW source reduction. Furthermore, the best investment level of CW source reduction was also determined. This study provides a model which can be used to simulate the cost-benefit under different implementation levels of reduction strategies and different investment levels in advance, thereby providing a reference for project decision-makers to plan CW source reduction.


Assuntos
Indústria da Construção , Gerenciamento de Resíduos , Gerenciamento de Resíduos/métodos , Análise Custo-Benefício , Materiais de Construção
4.
Environ Sci Pollut Res Int ; 29(26): 40213-40225, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-35119634

RESUMO

The Yellow River is an important ecological shelter zone and economic belt in China. However, rapid urbanization and industrialization has produced a fragile ecological environment conditions and unbalanced economic development in the Yellow River Basin (YRB). Ecological protection and high-quality development of the YRB has been China's national strategy since 2019. As the only coastal province with the largest economy and population in the YRB, the sustainable development of Shandong Province is of great importance in the region. This study evaluated the dynamic trend of sustainability levels of the nine cities in Shandong Province in the YRB through emergy analysis. Emergy-based indicators were established and analyzed from 2010 to 2019, taking account of the ecological service emergy (ESE) needed to dilute pollutants and emergy equivalent loss (EEL) on ecosystem quality and human health damage. Results showed that emergy sustainable indicators (ESI) in Tai'an, Heze, Dezhou, and Liaocheng ranged from 1 to 10, which had the potential for sustainable development. The ESI value of Jinan, Jining, Zibo, Dongying, and Binzhou was less than 1, which indicated that these cities were under great ecological pressure. The value of emergy indicators for sustainable development (EISD) of the nine cities all declined from 2010 to 2016, but remained stable from 2017 to 2019. Based on findings from the emergy analysis regarding policy implications and local conditions, the study concludes by providing proposals to improve regional sustainability.


Assuntos
Ecossistema , Rios , China , Cidades , Conservação dos Recursos Naturais , Humanos , Urbanização
5.
Waste Manag ; 137: 169-178, 2022 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-34785435

RESUMO

The economic instrument is an effective approach to encourage demolition contractors to conduct low-impact waste management. It is essential for project managers and decision-makers to better understand the cost-benefit of demolition waste (DW) management, to promote development of an effective waste management plan. This study explores the interactive dynamics and adaptive nature between stakeholders, where the cost-benefit of DW management is analysed through the agent-based modelling approach. Shenzhen, a leading city in China in the management of DW, was selected as the study area. It was revealed that if the traditional demolition method is adopted as the primary choice, the net benefit of demolition of buildings in the study case will reach -131.4 billion yuan, i.e. the cost will surpass the revenue. If the selective demolition method is widely used by demolition contractors, simulation results indicate that the net benefit will reach 33.3 billion yuan, an increase of 125.34%, compared to the situation in which the traditional demolition method is widely implemented. Based on the simulation, an optimal management framework for DW management stakeholders was constructed. The research results can provide a decision-making basis for the government and relevant departments to formulate DW management measures.


Assuntos
Indústria da Construção , Gerenciamento de Resíduos , Materiais de Construção , Análise Custo-Benefício , Resíduos Industriais , Análise de Sistemas
6.
J Environ Manage ; 295: 113112, 2021 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-34174685

RESUMO

Taking environmental protection into consideration, China introduced the new Environmental Protection Tax Law in 2018, which levies taxes for pollutants with higher standards. The vast majority of existing studies have investigated the impacts of environmental taxes (ETs) at the city level or province level. In contrast, we estimate their effects on pollutant reductions for fossil-fuel power plants in 30 provinces in China. Our results show that ETs have positive effects on pollutant emission reductions compared with the pollution discharge fee policy. We provide empirical evidence that sulfur dioxide (SO2), nitrogen oxide (NOx), and dust from fossil fuel power plants significantly decreased by 2.186 (7.7%), 1.550 (6.84%), and 1.064 (16.1%) tons, respectively, after the implementation of the policy. Moreover, there is an inverted U-shape relationship between pollutant emission reductions and tax rates. We offer further evidence that they play a limited role in high environmental regulation regions. Finally, we compare how different types of firms responded to ETs. The results show that ETs have limited effects on pollutant reductions for large state-owned coal power plants, which may have achieved environmental transformation to a certain extent. Therefore, policymakers could consider promoting tax rates in areas with low tax rates and strengthening tax breaks to stimulate firms to achieve pollutant reduction. In addition, local governments should set tax rates taking regional environmental regulation levels and firm heterogeneity into account.


Assuntos
Poluentes Atmosféricos , Poluição do Ar , Poluentes Atmosféricos/análise , Poluição do Ar/análise , Poluição do Ar/prevenção & controle , China , Combustíveis Fósseis , Centrais Elétricas , Impostos
7.
J Environ Manage ; 290: 112601, 2021 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-33895451

RESUMO

Due to the rapid social and economic development, the past decades have witnessed the improvement of human being's quality of life and the speedy development of the construction industry. Meanwhile, the illegal dumping of solid waste has presented a significant issue. By using the method of systematic review, this study critically examined the literature related to illegal dumping that were published since 1990, and analyzed the current status and future trends of related research. Results show that the current studies on illegal dumping mainly focus on four perspectives: environmental science and toxicology, economics, management, and the use of emerging technologies. This critical review revealed that although the issue of illegal dumping has been widely recognized in recent years, some questions remain unanswered. Therefore, a future research agenda is proposed. These include: (1) Identifying the migration of pollutants in the food chain during the illegal dumping; (2) Implementing targeted treatment of illegal dumping pollutants; (3) Improving the stakeholder decision analysis model; (4) Expanding the scope of research on stakeholders of illegal dumping; (5) Formulating an unified evaluation standard for the related costs of illegal dumping; (6) Strengthening the evaluation of the interaction effects of influencing factors; (7) Comparing the effects of different types of factors; (8) the exploration of other influencing factors; (9) Analyzing illegal dumping by combining big data with the amount of solid waste; (10) Combining with monitoring to analyze the illegal dumping of household waste.


Assuntos
Indústria da Construção , Eliminação de Resíduos , Gerenciamento de Resíduos , Custos e Análise de Custo , Humanos , Qualidade de Vida , Resíduos Sólidos
8.
Environ Sci Pollut Res Int ; 28(21): 26199-26214, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-33786761

RESUMO

Life cycle assessment (LCA) is widely used to quantify the environmental performance of buildings. Recently, the potential temporal variations in the lifetime of buildings and their influences on assessment results have attracted considerable attention. Dynamic LCA (DLCA) is an emerging research topic. This study provides an overview of the current scenario of DLCA studies in the building field. A literature survey was conducted by searching through scientific literature databases; 48 articles met the inclusion criteria. Eleven dynamic variables as well as their addressing approaches were summarized and analyzed. A few typical dynamic assessment models were synthesized and compared to present the methodology progress. Finally, considering the existing limitations, a few research directions were recommended: setting cutoff criteria for dynamic variables, developing a dynamic database, and considering the interactions between dynamic variables. The analyses in this study indicate that research on the DLCA of buildings needs interdisciplinary cooperation. This review promotes in-depth understanding about DLCA research of buildings and offers valuable implications for environmental practice. The highlighted future research directions facilitate further explorations in this research area.


Assuntos
Estágios do Ciclo de Vida , Animais
9.
J Environ Manage ; 272: 110998, 2020 Oct 15.
Artigo em Inglês | MEDLINE | ID: mdl-32854900

RESUMO

Environmental regulations affects the environmental quality of not only local areas but also surrounding regions. It remains unknown whether the effect of environmental regulations on the surrounding regions is free riding or pollution shelter. Based on the data from 2006 to 2018, the spatial correlation of PM2.5 in Beijing-Tianjin-Hebei (BTH), Yangtze River Delta (YRD) and Pearl River Delta (PRD) urban agglomerations in China was examined in this study. In addition, the spatial spillover effects of environmental regulation on PM2.5 concentrations were explored while the socio-economic driving factors of the heterogeneity of pollution spillover were identified via SDM based STIRPAT framework. Results showed that the characteristics of PM2.5 concentrations spatial correlations varies from one urban agglomeration to another. This study revealed that the air pollution is affected by not only local environmental regulations, but also regulations implemented in surrounding cities. The PM2.5 concentration of BTH, YRD and PRD increased by 0.76, 0.147 and 0.109 for each unit increase in environmental regulation of surrounding cities, respectively. In fact, cities with loose regulation become the pollution shelters. The spatial spillover effects offset the improvement effects of local environmental regulations on the air quality. Furthermore, the comparison amongst three urban agglomerations showed that the spatial spillover effects of PM2.5 concentration in BTH and YRD are higher than that of PRD. This is attributed to differences in industrial structure, population density, economic development, FDI and geographical location. Therefore, the spatial spillover effects should be taken into consideration and joint regulation should be strengthened to address air pollution issues in urban aggregations.


Assuntos
Poluentes Atmosféricos/análise , Poluição do Ar/análise , Pequim , China , Cidades , Monitoramento Ambiental , Material Particulado/análise
10.
Sci Total Environ ; 744: 140826, 2020 Nov 20.
Artigo em Inglês | MEDLINE | ID: mdl-32711310

RESUMO

China transitioned into "new normal phase" during 2007 to 2017, shifting from pursuing rapid GDP growth to a win-win state of economic development and environmental improvement. Using the input-output (IO) table for 2007-2012 and the latest IO table for 2012-2017, an IO model of China's industrial SO2 emissions is established and structural decomposition analysis (SDA) is applied to examine the changes in industrial SO2 emissions resulting from this economic transition. Five influencing factors (emission intensity, production technology, final demand expenditure, final demand structure and economic scale) are taken into consideration. The analysis shows that emission intensity and economic scale are the most influential factors on SO2 emissions. Emission intensity reduced SO2 emissions by 16,560,886 t in 2012-2017 whilst economic scale increased SO2 emissions by 473,490 t. Compared with the period 2007-2012, the contribution rate of emission intensity increased from -82.3% to -189.2%, while that of economic scale decreased from 131.8% to 54.1%. The total contributions of 5 factors to SO2 reduction increased from -5,249,417 t to -12,783,248 t, and the contribution rate increased from -24.8% to -146%. China's energy conservation and emission reduction has achieved remarkable results between 2007 and 2017. In "new normal phase", the slowing of China economic growth, the transition of economic development, industrial structural adjustment and rational consumption habits have had significant effects in reducing environmental pollution.

11.
Sci Total Environ ; 725: 138292, 2020 Jul 10.
Artigo em Inglês | MEDLINE | ID: mdl-32298887

RESUMO

The largest contributor to pollutant emissions is the sintering process in steel industry. Ultra-low emission policy for the Chinese steel industry states that emission concentrations of particulate matter, SO2 and NOx should not exceed 10, 35 and 50 mg/m3 respectively. The emission concentrations of the steel industry are the same as the ultra-low emission policy for the coal-fired power industry, but the pollutant control technologies of the two industries are different. Life cycle assessment method is applied to analyze the latest ultra-low treatment process for sintering flue gas emissions which includes electrostatic precipitation, ozone oxidation, wet desulfurization, wet denitration, condensation dehumidification and wet electrostatic precipitation. Following this novel ultra-low emission treatment, the concentrations of particulate matter, SO2, NOx, and PCDDs in the sintering flue gas decreased very significantly, attaining the new emission standard. With 1 ton of sinter as the functional unit and "cradle to gate" as the system boundary, the environmental impact of the process is 0.1811 and the total economic cost is 172.79 RMB, of which internal cost is 34.64 RMB and external cost is 138.15 RMB. The main environmental impacts result from applying the wet denitration and ozone oxidation processes. Sodium sulfite in the wet denitration process, and electricity and liquid oxygen in the ozone oxidation process are the key inputs that cause environmental impact. These findings are useful for a further optimization of the ultra-low emissions process from both the environmental and economic perspective, which is applicable in other regions of the world.

12.
Environ Sci Pollut Res Int ; 27(13): 14503-14514, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-32040743

RESUMO

Northern China suffers from serious air pollution especially in winter, much of which derives from solid fuel used for domestic heating in rural areas. In order to reduce pollution emissions in the heating season, the Chinese government has introduced a "coal-to-gas conversion" policy, promoting a switch to natural gas which is much cleaner than the coal normally used for winter heating. The "coal-to-gas conversion" project will cover more than 1.8 billion m2 of heated built floor area and affect more than 12 million heat users in Beijing, Tianjin, Hebei, and the surrounding areas. Life cycle assessment and life cycle cost methods are applied to compare and analyze the environmental impact and economic cost of household energy usage for the whole year under 5 scenarios before and after "coal-to-gas conversion." In the three scenarios after "coal-to-gas conversion," the environmental impact decreases by around 50% while the total economic cost increases by around 80%. Particulate emissions responsible for air pollution are considerably reduced with accompanying benefits for human health, though significant, but reduced, impacts on freshwater and marine ecotoxicity remain. Improving thermal efficiency through natural gas utilization, implementing an energy-saving retrofit of rural housing, and promoting straw utilization yield benefits for people and the environment in rural areas of northern China.


Assuntos
Poluição do Ar em Ambientes Fechados/análise , Poluição do Ar/análise , Pequim , China , Carvão Mineral/análise , Calefação , Humanos , Material Particulado/análise
13.
Environ Sci Pollut Res Int ; 26(25): 25432-25444, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31309421

RESUMO

With the rapid development of construction industry, consumption of concrete block has increased rapidly in China. As a kind of green building material and resource comprehensive utilization product, autoclaved aerated fly ash and concrete block have better performance in terms of heat preservation, sound insulation, and fire resistance. However, some typical issues are associated with autoclaved aerated fly ash and concrete block production process such as energy and material consumption as well as pollutant emissions. To examine the environmental and economic impacts of its production process is imperative. Choosing 1 m3 of autoclaved aerated fly ash and concrete block product as functional unit and "cradle to gate" as system boundary, a life cycle inventory is developed. The key processes and key materials with significant environmental impact are identified. Results show that the top four environmental impact categories are marine ecotoxicity, freshwater ecotoxicity, freshwater eutrophication, and human toxicity. Key processes are fly ash slurry production, lime grinding, and steam curing processes. These processes account for 46.58%, 26.00%, and 19.62% of the total environmental load respectively. The key materials are cement, lime, and natural gas, which account for 44.91%, 22.79%, and 20.61% respectively of overall environmental impact. Sensitivity analysis shows that the fly ash slurry production should be optimized preferentially, followed by lime grinding and steam curing processes. These findings are helpful to facilitate the sustainable production of autoclaved aerated fly ash and concrete block.


Assuntos
Cinza de Carvão/análise , Poluentes Ambientais/análise , China , Cinza de Carvão/química , Materiais de Construção , Meio Ambiente , Temperatura Alta , Humanos
14.
Waste Manag ; 81: 226-233, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30527040

RESUMO

High landfill charge presents an effective approach to divert construction waste from landfill. The stakeholders' willingness to pay (WTP) for the disposal of construction waste in landfill provide the useful information to set a reasonable charge level. Considering the diversity in stakeholder groups and regional socioeconomic conditions, contingent valuation method (CVM) was employed in this study to investigate the WTP of two major stakeholder groups in two typical Chinese cities. In addition, the perception of stakeholders towards landfill charge policy was measured and the impact of various factors on WTP was explored. The results indicated that there were statistically significant disparities of WTP between cities and stakeholder groups. Stakeholders from Shenzhen were willing to pay more than their counterparts in Qingdao. Contractors were willing to pay less than owners. Respondents who evaluate the policy as effective in reducing construction waste landfill were willing to pay more. However, firm size, ownership, position of respondent and perceived equity factors did not show statistically significant effect on WTP. These findings highlight the necessity to customize landfill charge policy according to local socioeconomic conditions.


Assuntos
Instalações de Eliminação de Resíduos/economia , China , Fatores Socioeconômicos , Inquéritos e Questionários , Volição
15.
Waste Manag ; 62: 69-75, 2017 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-28283224

RESUMO

Anaerobic digestion (AD), which is a process for generating biogas, can be applied to the treatment of organic wastes. Owing to its smaller footprint, lower energy consumption, and less digestate, high solid anaerobic digestion (HSAD) has attracted increasing attention. However, its biogas production is poor. In order to improve biogas production and decrease energy consumption, an improved thermal treatment process was proposed. Raw swine manure (>20% solid content) without any dilution was thermally treated at 70±1°C for different retention times, and then its effect on HSAD was investigated via batch AD experiments at 8.9% solid content. Results showed that the main organic components of swine manure hydrolyzed significantly during the thermal treatment, and HSAD's methane production rate was improved by up to 39.5%. Analysis using two kinetic models confirmed that the treatment could increase biodegradable organics (especially the readily biodegradable organics) in swine manure rather than upgrading its hydrolysis rate. It is worth noting that the superimposed first-order kinetics model was firstly applied in AD, and was a good tool to reveal the AD kinetics mechanism of substrates with complex components.


Assuntos
Eliminação de Resíduos/métodos , Anaerobiose , Temperatura Alta , Hidrólise , Cinética , Esterco , Modelos Teóricos
16.
Nanoscale ; 8(45): 18887-18892, 2016 Dec 07.
Artigo em Inglês | MEDLINE | ID: mdl-27824197

RESUMO

With the socio economic development, people have paid more and more attention to energy source problems, especially to clean and renewable energy such as hydrogen. It is appealing but still challenging to find or design an appropriate catalyst which is inexpensive and efficient for both the hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) in the same electrolyte. In this work, we develop a facile synthesis of amorphous defect-rich CoMoS4via a one-step hydrothermal method, and under alkaline conditions; the CoMoS4 electrode can generate a current density of 10 mA cm-2 at the overpotentials of 143 mV for HER and 342 mV for OER in 1.0 M KOH, respectively. A cell voltage of 1.72 V is required to achieve a current density of 10 mA cm-2 with long-term stability in an electrolyzer using the CoMoS4/CC electrode as both the anode and cathode.

17.
Environ Sci Pollut Res Int ; 23(24): 24796-24807, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27658407

RESUMO

Lignite is a low-quality energy source which accounts for 13 % of China's coal reserves. It is imperative to improve the quality of lignite for large-scale utilization. To further explore and analyze the influence of various key processes on the environment and economic costs, a lignite drying and compression technology is evaluated using an integrated approach of life cycle assessment and life cycle costs. Results showed that lignite mining, direct air emissions, and electricity consumption have most significant impacts on the environment. An integrated evaluation of life cycle assessment and life cycle costs showed that the most significant contributor to the environmental impacts and economic costs was the lignite mining process. The impact of transportation and wastewater treatment process on the environment and economic costs was small enough to be ignored. Critical factors were identified for reducing the environmental and economic impacts of lignite drying and compression technology. These findings provide useful inputs for both industrial practice and policy making for exploitation, processing, and utilization of lignite resources.


Assuntos
Carvão Mineral/análise , China , Eletricidade , Fontes Geradoras de Energia , Meio Ambiente , Mineração , Águas Residuárias/análise
18.
Virus Res ; 213: 205-213, 2016 Feb 02.
Artigo em Inglês | MEDLINE | ID: mdl-26732483

RESUMO

Chronic hepatitis B virus (HBV) infection (CHB) is a major cause of cirrhosis and hepatocellular carcinoma (HCC). Although the availability of HBV vaccines effectively reduces the incidence of HBV infection, the healthcare burden from CHB remains high. Several antiviral agents, such as (pegylated-) interferon-α and nucleos(t)ide analogs are approved by US FDA for chronic HBV infection management. Entecavir (ETV) and tenofovir disoproxil fumarate (TDF) have been recommended as the first-line anti-HBV drugs for excellent viral suppression with a low risk of antiviral resistance, but the cost and need for essentially life-long treatment are considerable challenges. And none of these current treatments can eradicate the intracellular virus. Given these issues, there is still an unmet medical need for an efficient HBV cure. We summarize here the key developments of antivirals against hepatitis B virus, including HBV replication cycle inhibitors and host immune regulators.


Assuntos
Antivirais/uso terapêutico , Hepatite B Crônica/tratamento farmacológico , Antivirais/economia , Antivirais/farmacologia , Vírus da Hepatite B/efeitos dos fármacos , Humanos
19.
Huan Jing Ke Xue ; 35(1): 286-91, 2014 Jan.
Artigo em Chinês | MEDLINE | ID: mdl-24720217

RESUMO

Acute toxicity of wastewater from 5 nodes of technological process in the pharmaceutical factory sewage treatment station was studied by luminescent bacteria tests. The EC50, TUa and LID of the wastewater in underground regulating tanks was 3.44%, 29 and 625, respectively, indicating the water was extremely/highly toxic; for the wastewater in surface regulating tanks, the EC50, TUa and LID was 2.46%, 41 and 244, respectively, also extremely/highly toxic; for the wastewater in middle sediment tanks, the EC50 > 100% and LID was 10, which was moderately toxic; for the wastewater in secondary sediment tanks and the final effluents, the EC50 was above 100% and LID was 1, with no observed toxicity. The results indicated that the existing treatment process effectively reduced the acute toxicity of the pharmaceutical wastewater to luminescent bacteria, the effluents showed no observed toxicity to luminescent bacteria, which was lower than the relative effluent limits of pharmaceutical wastewater. The wastewater in lower concentration did not inhibit the luminosity, but enhanced the luminosity.


Assuntos
Bactérias/efeitos dos fármacos , Indústria Farmacêutica , Águas Residuárias/toxicidade , Poluentes Químicos da Água/toxicidade , Luminescência
20.
J Am Coll Cardiol ; 63(12): 1159-1168, 2014 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-24509270

RESUMO

OBJECTIVES: The objective of this study was to evaluate the safety and efficacy of the surgical versus transcatheter approach to correct perimembranous ventricular septal defects (pmVSDs) in a prospective, randomized, controlled clinical trial. BACKGROUND: pmVSD is a common congenital heart disease in children. Surgical closure of pmVSD is a well-established therapy but requires open-heart surgery with cardiopulmonary bypass. Although the transcatheter approach is associated with significant incidence of complete atrioventricular block, it may provide a less invasive alternative. Critical comparison of the safety and efficacy of the 2 interventions necessitates a prospective, randomized, controlled trial. METHODS: Between January 2009 and July 2010, 229 children with pmVSD were randomly assigned to surgical or transcatheter intervention. Clinical, laboratory, procedural, and follow-up data over a 2-year period were compared. RESULTS: Neither group had mortality or major complications. However, statistical analysis of the 2 groups demonstrated significant differences (p < 0.001) in minor adverse events (32 vs. 7), quantity of blood transfused, duration of the procedure, median hospital stay, median intensive care unit stay, median hospitalization cost, and median blood loss. During a median follow-up of 2 years, the left ventricular end-diastolic dimension of both groups returned to normal and there was no difference in closure rate, adverse events, and complications between groups. CONCLUSIONS: Transcatheter device closure and surgical repair are effective interventions with excellent midterm results for treating pmVSD in children. Transcatheter device closure has a lower incidence of myocardial injury, less blood transfused, faster recovery, shorter hospital stay, and lower medical expenses. (Transcatheter Closure Versus Surgery of Perimembranous Ventricular Septal Defects; NCT00890799).


Assuntos
Cateterismo Cardíaco , Ponte Cardiopulmonar , Comunicação Interventricular/cirurgia , Dispositivo para Oclusão Septal , Alanina Transaminase/sangue , Aspartato Aminotransferases/sangue , Perda Sanguínea Cirúrgica , Transfusão de Sangue/estatística & dados numéricos , Nitrogênio da Ureia Sanguínea , Criança , Pré-Escolar , Creatinina/sangue , Ecocardiografia Doppler em Cores , Ecocardiografia Doppler de Pulso , Feminino , Comunicação Interventricular/diagnóstico por imagem , Ventrículos do Coração/diagnóstico por imagem , Hospitalização/economia , Humanos , Unidades de Terapia Intensiva Pediátrica , Tempo de Internação/estatística & dados numéricos , Masculino , Complicações Pós-Operatórias , Estudos Prospectivos , Troponina I/sangue , Septo Interventricular/diagnóstico por imagem
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