[Execute Yinpian drug catalogue, traditional Chinese medicine Yinpian prescription dispensing rule, completely solve the problem of the dispensing specified varieties].

For solve confusion of the dispensing specified varieties of traditional Chinese medicine Yinpian, the state administration of traditional Chinese medicine had decreed in 2009 the on the Traditional Chinese Medicine Yinpian prescription name and the dispensing specified varieties notification, Require various regions medical institutions to solve the problem. But the notification permit that each medical institutions formulate the traditional Chinese medicine Yinpian prescription name and standards of the dispensing Specified varieties, be sure to cause each medical institutions on parallel tracks in the dispensing Specified varieties. Beijing the Beijing traditional Chinese medicine Yinpian prescription dispensing rule. It nor did completely solve the problem of the dispensing specified varieties, there is a difference between doctor and harmacist. So formulate statute universal and scientific, Completely solve the problem of the dispensing specified varieties, It is Long-cherished wish of government and traditional Chinese medicine sector for many years The article on appearance of the dispensing specified varieties problem, and think about actual statute of the dispensing specified varieties, and discuss Solving system, consider formulate and execute Yinpian drug catalogue and Chinese medicine Yinpian prescription dispensing rule by country and local two level, It provides legal protection to thoroughly resolve the dispensing Specified varieties Both can resolve that prescription of traditional Chinese medicine Yinpian unified provisioning in entire country, And conducive to defend local medical genre medication features, and defend precious local features processing varieties and conducive to exploit new drug, and conducive to inherit and evolve traditional Chinese medicine scientifically, It is simple and feasible final way to Chinese medicine Yinpian dispensing specified varieties.

Perpetrators of pharmacokinetic drug-drug interactions arising from altered cytochrome P450 activity: a criteria-based assessment.

AIMS: To catalogue the perpetrators of CYP-mediated pharmacokinetic drug-drug interactions (PK-DDIs) using clinically relevant criteria, and to compare this with an analogous catalogue. METHODS: Candidate inhibitors and inducers of CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A ('perpetrators') were evaluated using published clinical pharmacokinetic interaction studies. Studies were selected on the basis of ≥six human subjects, use of a validated in vivo probe substrate for the CYP enzyme, and clinically relevant dosing. Inhibitors were described according to the FDA classifications of strong, moderate or weak, whereas inducers were classified as major (≥twofold decrease in AUC) or weak (

[How do general practitioners keep up-to-date on pharmacotherapy?]. / Hvordan holder allmennleger seg oppdatert om legemidler?

BACKGROUND: Traditional methods for dissemination of knowledge, such as lecture-based courses and distribution of guidelines, have shown only modest effect on improving the quality of GPs' prescription practice. We aimed at assessing GPs' own views on various sources of knowledge within pharmacotherapy, and their attitudes to a potentially effective educational method: audit and feedback. MATERIAL AND METHODS: A questionnaire regarding the use of and views on various sources of knowledge concerning pharmacotherapy was sent to GPs in continuing medical education (CME) groups participating in an intervention study on quality improvement of prescription practice. RESULTS: 302 of 479 GPs (63 %) responded. The Norwegian Pharmaceutical Catalogue was the most widely used source of information on drugs. Industry- based sources were generally regarded as less useful and without great influence on prescription practice, but were nevertheless often mentioned as a source of information in specific prescribing situations. The GPs rated CME groups as useful and influential, and 94 % viewed the exposure of own prescription data in the CME group as unproblematic. INTERPRETATION: Audit and feedback in CME groups seems to be a suitable educational method in pharmacotherapy. Industry- based information sources are rated as being of low value, but seem to have influence on prescription practice.

La medicina en Luján en el siglo XVIII. Referencias al ejercicio de la Medicina en el año 1780 época del Virreinato del Río de la Plata en jurisdicción del Cabildo de Luján / Practice of Medicine at the city of Luján, Buenos Aires Province, during 18º Century

This report describes the practice of Medicne in the city of Luján, Buenos Aires Province, during the 18º century

[Computerized decision support in drug prescribing II: A national database to provide up-to-date and unbiased information]. / Datorn som beslutsstöd vid läkemedelsförskrivning. II: Nationell databas skall ge uppdaterad och obunden information.

Prescribers today encounter increasing demands for up-to-date knowledge of medical advances and drug therapies, and for a straightforward dialogue with patients. Cost-effective drug treatment calls for fast and intuitive access to information about drugs, treatment strategies and patient data. There are several computer-based drug-prescribing systems in Sweden. Information independent of the drug industry is wanting, as are uniform national standards for medical content and functionality. Decision-support systems must facilitate decisions about therapy, drug distribution and intake, as well as quality work, i.e. support the entire process which defines an effective drug therapy. A very important feature is access to a patient's drug list showing all current drugs. This joint initiative by county councils aims at drawing up a national Swedish specification of requirements for a suitable decision-support system and at creating a national entity responsible for distributing unbiased information from a unique database to a range of computerized medical records systems.

Evolución histórica de los medicamentos no incluidos en la lista oficial (claves) de la CCSS / Historical evolution of medicines not including in the official list (key) of the CCSS

En el contexto de la Seguridad Social de Costa Rica se cuenta con la Lista Oficial de Medicamentos (LOM), que traduce la selección de los fármacos necesarios para atender las necesidades sanitarias de la población asegurada. Como un mecanismo para dar resolución a necesidades excepcionales de medicamentos, se dispone de la opción para gestionar claves de autorización para medicamentos no LOM a cargo institucional. El objetivo de esta presentación es exponer una breve reseña de la evolución histórica de las claves, con base en la información contenida en los archivos disponibles y las base de datos. La alternativa del sistema de claves para medicamentos no LOM se ha documentado desde 1985, cuando se otorgaron 387 claves. La confirmación de un constante crecimiento de las claves confirma la vigencia de esta alternativa a lo largo de los años, hasta llegar a 3848 claves durante el año 2001, aunque la gran mayoría de los producos autorizados a la fecha ya están incluidos en a LOM. Durante el primer semestre de 2002, los medicamentos más solicitados fueron Angiotensina II, Capecitabina, los inhibidores de Aroatasa (letrozol y otros) y la Amifostina. Se concluye que la opción de brindar medicamenots no LOM a cargo institucional a una minoría de pacientes tributarios, que por su condición clínica diferencial o por la excepcionalidad de su diagnóstico no está cubierto, constituye un recurso real en procura de asegurar una intervención farmacológica eficaz y segura a los pacientes. Palabras clave: Medicamentos, fármacos, Lista Oficial de Medicamentos.