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1.
J Egypt Natl Canc Inst ; 36(1): 22, 2024 Jun 24.
Artigo em Inglês | MEDLINE | ID: mdl-38910202

RESUMO

BACKGROUND: Innovations in cancer treatment have contributed to the improved survival rate of cancer patients. The cancer survival rates have been growing and nearly two third of those survivors have been exposed to clinical radiation during their treatment. The study of long-term radiation effects, especially secondary cancer induction, has become increasingly important. An accurate assessment of out-of-field/peripheral dose (PDs) is necessary to estimate the risk of second cancer after radiotherapy and the damage to the organs at risk surrounding the planning target volume. This study was designed to measure the PDs as a function of dose, distances, and depths from Telecobalt-60 (Co-60) beam in water phantom using thermoluminescent dosimeter-100 (TLD-100). METHODS: The PDs were measured for Co-60 beam at specified depths of 0 cm (surface), 5 cm, 10 cm, and 15 cm outside the radiation beam at distances of 5, 10, and 13 cm away from the radiation field edge using TLD-100 (G1 cards) as detectors. These calibrated cards were placed on the acrylic disc in circular tracks. The radiation dose of 2000 mGy of Co-60 beam was applied inside 10 × 10 cm2 field size at constant source to surface distance (SSD) of 80 cm. RESULTS: The results showed maximum and minimum PDs at surface and 5 cm depth respectively at all distances from the radiation field edge. Dose distributions out of the field edge with respect to distance were isotropic. The decrease in PDs at 5 cm depth was due to dominant forward scattering of Co-60 gamma rays. The increase in PDs beyond 5 cm depth was due to increase in the irradiated volume, increase in penumbra, increase in source to axis distance (SAD), and increase in field size due to inverse square factor. CONCLUSION: It is concluded that the PDs depends upon depth and distance from the radiation field edge. All the measurements show PDs in the homogenous medium (water); therefore, it estimates absorbed dose to the organ at risk (OAR) adjacent to cancer tissues/planning target volume (PTV). It is suggested that PDs can be minimized by using the SAD technique, as this technique controls sources of scattered radiation like inverse square factor and effect of penumbra up-to some extent.


Assuntos
Radioisótopos de Cobalto , Imagens de Fantasmas , Dosagem Radioterapêutica , Dosimetria Termoluminescente , Humanos , Dosimetria Termoluminescente/métodos , Água , Planejamento da Radioterapia Assistida por Computador/métodos , Neoplasias/radioterapia , Doses de Radiação , Órgãos em Risco/efeitos da radiação
2.
Radiat Res ; 200(4): 357-365, 2023 10 01.
Artigo em Inglês | MEDLINE | ID: mdl-37702413

RESUMO

Significant past work has identified unexpected risks of central nervous system (CNS) exposure to the space radiation environment, where long-lasting functional decrements have been associated with multiple ion species delivered at low doses and dose rates. As shielding is the only established intervention capable of limiting exposure to the dangerous radiation fields in space, the recent discovery that pions, emanating from regions of enhanced shielding, can contribute significantly to the total absorbed dose on a deep space mission poses additional concerns. As a prerequisite to biological studies evaluating pion dose equivalents for various CNS exposure scenarios of mice, a careful dosimetric validation study is required. Within our ultimate goal of evaluating the functional consequences of defined pion exposures to CNS functionality, we report in this article the detailed dosimetry of the PiMI pion beam line at the Paul Scherrer Institute, which was developed in support of radiobiological experiments. Beam profiles and contamination of the beam by protons, electrons, positrons and muons were characterized prior to the mice irradiations. The dose to the back and top of the mice was measured using thermoluminescent dosimeters (TLD) and optically simulated luminescence (OSL) to cross-validate the dosimetry results. Geant4 Monte Carlo simulations of radiation exposure of a mouse phantom in water by charged pions were also performed to quantify the difference between the absorbed dose from the OSL and TLD and the absorbed dose to water, using a simple model of the mouse brain. The absorbed dose measured by the OSL dosimeters and TLDs agreed within 5-10%. A 30% difference between the measured absorbed dose and the dose calculated by Geant4 in the dosimeters was obtained, probably due to the approximated Monte Carlo configuration compared to the experiment. A difference of 15-20% between the calculated absorbed dose to water at a 5 mm depth and in the passive dosimeters was obtained, suggesting the need for a correction factor of the measured dose to obtain the absorbed dose in the mouse brain. Finally, based on the comparison of the experimental data and the Monte Carlo calculations, we consider the dose measurement to be accurate to within 15-20%.


Assuntos
Mésons , Animais , Camundongos , Radiometria/métodos , Prótons , Sistema Nervoso Central , Método de Monte Carlo , Dosimetria Termoluminescente/métodos , Água , Imagens de Fantasmas
3.
Appl Radiat Isot ; 188: 110419, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-35988526

RESUMO

Various thicknesses of 2B grade polymer pencil lead graphite (PPLG) were used in the present study, which focussed on the alteration in crystalline lattice and the structural defect caused by the electron irradiation dosage ranging from 0.5 to 20 Gy delivered by an Elekta HD Linac. The fundamental trap parameters i.e. kinetics order (b), activation energy (E), and frequency factor (s) of the PPLG samples have been estimated using the initial rise and peak shape approaches by fitting the thermoluminescence (TL) glow peaks of the PPLG samples exposed to 20 Gy. The lifetime of the TL glow peak is also presented, which provides information on the stability of the TL signal at maximum temperatures. Raman, Photoluminescence (PL), and X-ray diffraction (XRD) spectra are being used to observe the structural changes that have occurred as a result of the radiation doses. These spectroscopies offer an understanding of the physical parameters that are related to the defects and taking part in the luminescence process. When all of the data are taken into account, it is anticipated that 0.3 mm PPLG is an effective material for dosimetry. The results of these lines of research are intended to educate the innovation of versatile graphite radiation dosimeters as a low-cost efficient system for radiation detection. The studied PPLG offers tissue equivalence as well as high spatial resolution, both are desirable criteria for a material to be used in the monitoring of ionising radiation or a variety of medical applications.


Assuntos
Grafite , Dosimetria Termoluminescente , Elétrons , Medições Luminescentes , Radiometria , Dosimetria Termoluminescente/métodos
4.
Radiat Res ; 197(6): 650-654, 2022 06 01.
Artigo em Inglês | MEDLINE | ID: mdl-35258625

RESUMO

Irradiation protocols for murine experiments often use standardized dose rate estimates for calculating dose delivered, regardless of physical variations between mouse subjects. This work sought to determine the significance of mouse size on absorbed dose. Five mouse-like phantoms of various sizes based on the mouse whole-body (MOBY) model were 3D printed. The phantoms were placed in an X-Rad320 biological irradiator and a standard irradiation protocol was used to deliver dose. Dose was measured using thermoluminescent dosimeter (TLD) microcubes inside each phantom, and the relative readings were used to calculate output factors (OFs), normalized to the phantom of median volume. Additionally, the OF for each mouse was simulated in Monte Carlo N-Particle (MCNP) code. For both the TLD measurements and MCNP simulations, the OF for each mouse was determined by both experiments and calculations to be unity within the relative standard uncertainties (k = 1). This work supports comparing results across various studies using the X-Rad320 irradiator without need for corrections based on mouse size.


Assuntos
Dosimetria Termoluminescente , Animais , Camundongos , Método de Monte Carlo , Imagens de Fantasmas , Dosimetria Termoluminescente/métodos , Incerteza
5.
Radiat Environ Biophys ; 60(2): 257-265, 2021 05.
Artigo em Inglês | MEDLINE | ID: mdl-33864119

RESUMO

The present paper proposes a novel method, based on Bayesian statistics, as a new approach in the field of thermoluminescence dosimetry for the assessment of personal doses in mixed beta-gamma radiation fields. The method can be utilized in situations when the classical way of dose calculation is insufficient or impossible. The proposed method uses a prior function which can be assigned to the unknown parameter and the likelihood function obtained from an experiment, which together can be transformed into the posterior probability distribution of the sought parameter. Finally, the distribution is converted to the value of the dose. The proposed method is supported by analytical and Monte Carlo calculations, which confirmed the results obtained through the Bayesian approach.


Assuntos
Dosimetria Termoluminescente/métodos , Teorema de Bayes , Partículas beta , Radioisótopos de Césio , Raios gama , Humanos , Método de Monte Carlo , Radioisótopos de Estrôncio
6.
PLoS One ; 15(12): e0241550, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33378398

RESUMO

For x- and gamma- irradiations delivering entrance doses from 2- up to 1000 Gy to commercial 1.0 mm thick borosilicate glass microscope slides, study has been made of their thermoluminescence yield. With an effective atomic number of 10.6 (approximating bone equivalence), photon energy dependency is apparent in the low x-ray energy range, with interplay between the photoelectric effect and attenuation. As an example, over the examined dose range, at 120 kVp the photon sensitivity has been found to be some 5× that of 60Co gamma irradiations, also with repeatability to within ~1%. The glow-curves, taking the form of a single prominent broad peak, have been deconvolved yielding at best fit a total of five peaks, the associated activation energies and frequency factors also being obtained. The results indicate borosilicate glass slides to offer promising performance as a low-cost passive radiation dosimeter, with utility for both radiotherapy and industrial applications.


Assuntos
Compostos de Boro/química , Fótons , Dosímetros de Radiação , Silicatos/efeitos da radiação , Dosimetria Termoluminescente/instrumentação , Compostos de Boro/efeitos da radiação , Relação Dose-Resposta à Radiação , Raios gama , Humanos , Doses de Radiação , Silicatos/química , Dosimetria Termoluminescente/métodos , Raios X
7.
Eur J Radiol ; 126: 108950, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-32199141

RESUMO

PURPOSE: To quantify the eye lens, peak skin and brain doses associated with head CT perfusion exam by means of thermoluminescent dosimeters (TLDs) measurements in a cadaver and compare them to Monte Carlo (MC) dose estimations as well as to the CTDIvol. METHOD: 18 TLDs were inserted in the brain, skin, and eye lenses of a female cadaver head, who underwent a CT brain perfusion scan using a Siemens Definition Flash. The table-toggling protocol used 80 kVp, 200 mAs, 32 × 1.2 mm collimation and 30 sequences. From the CT images, a voxel model was created. Doses were calculated with a MC framework (EGSnrc) and compared to TLD measurements. TLD measurements were also compared to the displayed CTDIvol. RESULTS: The average measured doses were: 185 mGy for the eyes lenses, 107 mGy for the skin, 172 mGy for the brain and 273 mGy for the peak skin. The reported CTDIvol of 259 mGy overestimated the averaged organ doses but not the peak skin dose. MC estimated organ doses were 147 mGy for the eyes (average), 104 mGy for the skin and 178 mGy for the brain (-20 %, -3% and 4% difference respect to the TLDs measurements, respectively). CONCLUSIONS: CTDIvol remains a conservative metric for average brain, skin and eyes lenses doses. For accurate eye lens and skin dose estimates MC simulations can be used. CTDIvol should be used with caution as it was of the same order of magnitude as the peak skin dose for this protocol and this particular CT scanner.


Assuntos
Encéfalo/diagnóstico por imagem , Cristalino , Método de Monte Carlo , Doses de Radiação , Pele , Tomografia Computadorizada por Raios X/métodos , Cadáver , Feminino , Humanos , Radiometria/métodos , Dosimetria Termoluminescente/métodos , Dosimetria Termoluminescente/estatística & dados numéricos , Tomografia Computadorizada por Raios X/estatística & dados numéricos
8.
Phys Med Biol ; 65(5): 05NT01, 2020 03 06.
Artigo em Inglês | MEDLINE | ID: mdl-32028274

RESUMO

This paper presents a practical method for converting dose measured with thermoluminescent dosimeters (TLD) to dose in lung and bone for 6 MV and 15 MV photon beams. Monte Carlo (MC) simulations and Burlin cavity theory calculations were performed to calculate [Formula: see text], the dose-to-TLD to dose-to-medium conversion factor. A practical method was proposed for converting TLD-measured-dose to dose-in-medium using the TLD dose calibration in water and [Formula: see text] dose-to-medium to dose-to-water conversion factor. Theoretical calculations for [Formula: see text] were performed using photon spectrum weighted parameters and were compared with MC simulations. Verification of the proposed method was done using phantoms having either bone or lung equivalent slabs stacked in between solid water slabs. Percent depth dose (PDD) curves were measured using 0.089 cm thick LiF:Mg,Ti (TLD-100) dosemeters placed at various depths within these phantoms. They were then corrected with [Formula: see text] factors using the proposed dose conversion method, and were compared with the MC simulations. For 6 MV beam, the MC calculated [Formula: see text] factors were 0.942 and 1.002 for bone and lung, and for 15 MV it was 0.927 and 1.005 for bone and lung, respectively. The difference between the MC simulated and spectrum weighted theoretical [Formula: see text] factors were within 3% for both lung and bone. The PDD curves measured with TLD-100 chips that were corrected using the proposed method agreed well within 1.5% of the MC simulated PDD curves for both the water/lung/water and water/bone/water (WBW) phantoms. The dose-to-medium correction using MC simulated [Formula: see text] is convenient, easy, and accurate. Therefore, it can be used instead of Burlin cavity theory, especially in media with high atomic numbers such as bone for accurate dose quantification.


Assuntos
Algoritmos , Osso e Ossos/diagnóstico por imagem , Pulmão/diagnóstico por imagem , Imagens de Fantasmas , Fótons , Dosimetria Termoluminescente/métodos , Humanos , Método de Monte Carlo , Doses de Radiação
9.
Radiat Environ Biophys ; 59(2): 331-336, 2020 05.
Artigo em Inglês | MEDLINE | ID: mdl-32088744

RESUMO

A major disadvantage of dose reconstruction by means of thermoluminescence (TL) is the fact that during readout of any TL material exposed to ionizing radiation (i.e., during measuring the glow curve), the radiation-induced signal gets lost. Application of the photo-transferred thermoluminescence phenomenon (PTTL) may offer a solution to this problem. In PTTL, the residual signal that is not destroyed by conventional TL readout (because it comes from deeper electron traps) can be readout through simultaneous stimulation by UV light and heating, allowing to obtain information about the absorbed dose in a second run. The present paper describes the application of PTTL for emergency dose assessment. For this, MTS-N thermoluminescent detectors (LiF: Mg, Ti) were exposed using a high-energy Clinac 2300 medical linear accelerator to doses of 100 mGy, 300 mGy, 500 mGy, 700 mGy and 1000 mGy. Irradiation with UV radiation allowed the determination of the optimal heating time of 3 h, while the optimal temperature was identified to be 70 °C. The results obtained demonstrated the usefulness of the PTTL method for emergency dose assessment. The efficiency of the PTTL method was determined as 19%. Finally it was found that the detector background after UV exposure should not be underestimated during routine dose measurements.


Assuntos
Dosimetria Termoluminescente/métodos , Aceleradores de Partículas , Temperatura , Raios Ultravioleta
10.
Phys Med ; 69: 127-133, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31901837

RESUMO

In the last few years there has been an increasing interest in the measurement of the absorbed dose from radionuclides, with special attention devoted to molecular radiotherapy treatments. In particular, the determination of the absorbed dose from beta emitting radionuclides in liquid solution poses a number of issues when dose measurements are performed using thermoluminescent dosimeters (TLD). Finite volume effect, i.e. the exclusion of radioactivity from the volume occupied by the TLD is one of these. Furthermore, TLDs need to be encapsulated into some kind of waterproof envelope that unavoidably contributes to beta particle attenuation during the measurement. The purpose of this study is twofold: I) to measure the absorbed dose to water, Dw, using LiF:Mg,Cu,P chips inside a PMMA cylindrical phantom filled with a homogenous 90YCl3 aqueous solution II) to assess the uncertainty budget related to Dw measurements. To this purpose, six cylindrical PMMA phantoms were manufactured at ENEA. Each phantom can host a waterproof PMMA stick containing 3 TLD chips encapsulated by a polystyrene envelope. The cylindrical phantoms were manufactured so that the radioactive liquid environment surrounds the whole stick. Finally, Dw measurements were compared with Monte Carlo (MC) calculations. The measurement of absorbed dose to water from 90YCl3 radionuclide solution using LiF:Mg,Cu,P TLDs turned out to be a viable technique, provided that all necessary correction factors are applied. Using this method, a relative combined standard uncertainty in the range 3.1-3.7% was obtained on each Dw measurement. The major source of uncertainty was shown to be TLDs calibration, with associated uncertainties in the range 0.7-2.2%. Comparison of measured and MC-calculated absorbed dose per emitted beta particle provided good results, with the two quantities being in the ratio 1.08.


Assuntos
Cobre/química , Fluoretos/química , Compostos de Lítio/química , Magnésio/química , Fósforo/química , Dosimetria Termoluminescente/instrumentação , Dosimetria Termoluminescente/métodos , Radioisótopos de Ítrio , Algoritmos , Calibragem , Humanos , Método de Monte Carlo , Imagens de Fantasmas , Dosímetros de Radiação , Radioisótopos , Radiometria , Reprodutibilidade dos Testes , Água/química
11.
Sci Rep ; 9(1): 9691, 2019 07 04.
Artigo em Inglês | MEDLINE | ID: mdl-31273279

RESUMO

Monte Carlo (MC) simulation is a simpler radiation dose assessment method than the conventional method, thermoluminescent dosimetry (TLD). MC simulation and TLD were compared as tools to evaluate the effective dose from paediatric panoramic radiography. Various exposure conditions and machine geometries were simulated using the MC method to investigate factors resulting in effective dose reduction. The effective dose of paediatric panoramic radiography was obtained using an MC simulation and its reliability was verified by a comparison with the value obtained using TLD. Next, 7 factors determining the effective dose in the MC simulation were input with 6 equally-spaced values, and a total of 36 simulations were performed to obtain effective dose values. The correlations between each dose-determining factor and the resulting effective dose were evaluated using linear regression analysis. The TLD-measured dose was 3.850 µSv, while the MC simulation yielded a dose of 3.474 µSv. Beam height was the factor that most strongly influenced the effective dose, while rotation angle and focus-to-patient distance were the least influential factors. MC simulation is comparable to TLD for obtaining effective dose values in paediatric panoramic radiography. Obtaining panoramic radiography with a short beam height can effectively reduce the dose in paediatric patients.


Assuntos
Cabeça/diagnóstico por imagem , Método de Monte Carlo , Pescoço/diagnóstico por imagem , Órgãos em Risco/efeitos da radiação , Imagens de Fantasmas , Radiografia Panorâmica/métodos , Dosimetria Termoluminescente/métodos , Pré-Escolar , Humanos , Doses de Radiação , Dosimetria Termoluminescente/instrumentação
12.
Radiat Prot Dosimetry ; 186(4): 462-468, 2019 Dec 31.
Artigo em Inglês | MEDLINE | ID: mdl-31329977

RESUMO

Long exposure to radiation from fluoroscopy-guided interventions (FGIs) can be detrimental to both patients and radiologists. The effective doses received by the interventional radiology staff after performing 230 FGIs in a year were assessed by using double dosimetry and five various algorithms. The Shapiro-Wilk test revealed normally-distributed data (p < 0.01), while the significant correlation coefficients between the effective doses ranged between 0.88 and 1.00. As for the Bland-Altman analysis, both Niklason and Boetticher algorithms strongly supported the absence of statistical significance between the estimated effective doses. This portrays that the occupational doses received by the interventional radiology staff during FGIs fall within the acceptable limit regardless of the varied algorithms applied. In short, the Niklason and Boetticher algorithms appeared to be the more interchangeable ones for effective evaluation of doses. This is in view of their strong mutual correlations and excellent agreement.


Assuntos
Algoritmos , Fluoroscopia/métodos , Exposição Ocupacional/análise , Lesões por Radiação/prevenção & controle , Proteção Radiológica/métodos , Radiologia Intervencionista/métodos , Dosimetria Termoluminescente/métodos , Humanos , Doses de Radiação , Radiologistas
13.
Med Phys ; 46(7): 3217-3226, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30950071

RESUMO

PURPOSE: The aim of this study was to investigate thermoluminescent dosimeters (TLD) and radiochromic EBT3 film inside MR/CT visible geometric head and thorax phantoms in the presence of: 0, 0.35, and 1.5 T magnetic fields. METHODS: Thermoluminescent Dosimeters reproducibility studies were examined by irradiating IROC-Houston's TLD acrylic block five times under 0 and 1.5 T configurations of Elekta's Unity system and three times under 0 and 0.35 T configurations of ViewRay's MRIdian Cobalt-60 (60 Co) system. Both systems were irradiated with an equivalent 10 × 10 cm2 field size, and a prescribed dose of 3 Gy to the maximum depth deposition (dmax). EBT3 film and TLDs were investigated using two geometrical Magnetic Resonance (MR)-guided Radiation Therapy (MRgRT) head and thorax phantoms. Each geometrical phantom had eight quadrants that combined to create a centrally located rectangular tumor (3 × 3 × 5 cm3 ) surrounded by tissue to form a 15 × 15 × 15 cm3 cubic phantom. Liquid polyvinyl chloride plastic and Superflab were used to simulate the tumor and surrounding tissue in the head phantom, respectively. Synthetic ballistic gel and a heterogeneous in-house mixture were used to construct the tumor and surrounding tissue in the thorax phantom, respectively. EBT3 and double-loaded TLDs were used in the phantoms to compare beam profiles and point dose measurements with and without magnetic fields. GEANT4 Monte Carlo simulations were performed to validate the detectors for both Unity 0 T/1.5 T and MRIdian 0 T/0.35 T configurations. RESULTS: Average TLD block measurements which, compared the magnetic field effects (magnetic field vs 0 T) on the Unity and MRIdian systems, were 0.5% and 0.6%, respectively. The average ratios between magnetic field effects for the geometric thorax and head phantoms under the Unity system were -0.2% and 1.6% and for the MRIdian system were 0.2% and -0.3%, respectively. Beam profiles generated with both systems agreed with Monte Carlo measurements and previous literature findings. CONCLUSIONS: TLDs and EBT3 film dosimeters could potentially be used in MR/CT visible tissue equivalent phantoms that will experience a magnetic field environment.


Assuntos
Dosimetria Fotográfica/métodos , Campos Magnéticos , Imageamento por Ressonância Magnética , Dosimetria Termoluminescente/métodos , Tomografia Computadorizada por Raios X , Método de Monte Carlo , Imagens de Fantasmas
14.
Radiat Prot Dosimetry ; 185(3): 303-309, 2019 Dec 31.
Artigo em Inglês | MEDLINE | ID: mdl-30806472

RESUMO

The objective of this study is to determine the energy response factors for BeO optically simulated dosemeter (OSLD) using general cavity theory and Monte Carlo (MC) simulations. A virtual phantom is constructed in EGSnrc MC program and energy response of BeO OSLDs were simulated at 5 cm depth for x-ray beams ranging from 1.25 to 25 MV and at 2 cm for beams with <250 kV including ISO 4037 narrow beam energies in a virtual water phantom. The energy response factor for a given radiation quality relative to 60Co was determined for BeO and compared to the Al2O3:C and LiF:Mg,Ti dosemeters. Burlin cavity theory calculations were done using mean photon energy (MPE) of the beam spectra, while EGSnrc software package was used to carry out MC simulation of full spectra. The cavity theory and MC methods agreed well within the 0.7%. Energy response of x-ray beams at MV range showed a maximum of 1.5% under-response. At energies higher than 150 kV (105 keV MPE) showed no significant difference while a significant under-response were observed at 100 kV (53 keV MPE) and 50 kV (29 keV MPE), ~8 and ~12%, respectively. BeO, Al2O3:C and LiF:Mg,Ti dosemeters exhibited very similar energy response at higher energies mainly in the MeV range. At 50 kV (29 keV MPE), however, BeO dosemeter under responded by a factor of 0.878, while Al2O3:C and LiF:Mg,Ti dosemeters over responded by a factor of 3.2 and 1.44, respectively. Furthermore, at low energies, BeO energy response showed dependence on photon spectra. For instance, at 100 kV, the difference was ~8, ~6 and 2% for 53, 60 and 83 keV MPE (ISO 4037N-100), respectively. Furthermore, calibration with 137Cs instead of 60Co resulted up to 1.8% differences in energy response. Both energy spectrum and calibration methods make considerable differences in energy response of OSLDs. This study concludes that BeO chips are nearly energy independent at energies higher than 100 keV MPE, while Al2O3:C dosemeters show an extremely enhanced energy-response ranging between 1.44 and 3.2 at energies between 170 and 29 keV MPE mainly due to dominance of photoelectric effect.


Assuntos
Berílio/química , Modelos Teóricos , Método de Monte Carlo , Imagens de Fantasmas , Dosimetria Termoluminescente/instrumentação , Dosimetria Termoluminescente/métodos , Calibragem , Radioisótopos de Césio/química , Radioisótopos de Cobalto/química , Humanos , Doses de Radiação
15.
Health Phys ; 116(5): 590-598, 2019 05.
Artigo em Inglês | MEDLINE | ID: mdl-30624351

RESUMO

Portable x-ray fluorescence devices have grown in popularity for possible metal exposure assessment using in vivo measurements of bone and toenail. These measurements are accompanied by a small radiation dose, which is typically assessed by radiation safety committees to be minimal. However, an understanding of precise dose under different instrument conditions is still needed. This study set out to do a thorough investigation of the exact dose measurements using optically stimulated dosimeters, thermoluminescent dosimeters, and simulation with a Monte Carlo N-Particle transport code to assess the skin and total-body effective dose typical of portable x-ray fluorescence devices. We showed normal linear relationships between measurement time, x-ray tube current, and radiation dose with the device, and we showed a second order polynomial relationship with increasing voltage and radiation dose. Dose was quantified using thermoluminescent dosimeters, optically stimulated dosimeters, and simulations, which gave similar dose estimations. Skin dose for a standard 50-kV, 40-µA measurement for bone and toenail in vivo was 48.5 and 28.7 mSv, respectively, according to simulation results. Total-body effective dose was shown as 3.4 and 2.0 µSv for in vivo bone and toenail measurements, respectively, for adults using the portable x-ray fluorescence device.


Assuntos
Osso e Ossos/efeitos da radiação , Fluorescência , Metais/análise , Unhas/efeitos da radiação , Imagens de Fantasmas , Radiometria/métodos , Dosimetria Termoluminescente/métodos , Adulto , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Método de Monte Carlo , Doses de Radiação , Pele/efeitos da radiação
16.
Radiat Prot Dosimetry ; 185(2): 266-273, 2019 Dec 23.
Artigo em Inglês | MEDLINE | ID: mdl-30624748

RESUMO

The calibration of low energy X-ray experimental setup with strongly filtered beam dedicated to radiobiological research was performed using the absorbed dose calculated from the data collected by two types detectors. For this purpose a semiconductor (Amptek, USA) and a thermoluminescent (Institute of Nuclear Physics, Krakow, Poland) detectors were applied. The absorbed dose in water values estimated by both detectors are in good agreement.


Assuntos
Imagens de Fantasmas , Semicondutores/normas , Dosimetria Termoluminescente/instrumentação , Dosimetria Termoluminescente/normas , Carga Corporal (Radioterapia) , Calibragem , Humanos , Método de Monte Carlo , Eficiência Biológica Relativa , Dosimetria Termoluminescente/métodos , Raios X
17.
Radiat Prot Dosimetry ; 184(2): 216-223, 2019 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-30496554

RESUMO

In this work, the initial results of the type testing of the LiF:Mg,Cu,P (TLD-100H) whole-body personal dosemeters are presented. An assessment of reproducibility, linearity of the response, the residual signal as a function of the dose, energy and angular dependence of the response was performed. In general, the dosemeters show good reproducibility for different dose values and a linear behaviour for a range between 0.1 and 300 mSv. The detection limits obtained are lower than 50 µSv. The system presents a good energy and angular response for different radiation qualities.


Assuntos
Cobre/análise , Fluoretos/análise , Compostos de Lítio/análise , Magnésio/análise , Fósforo/análise , Monitoramento de Radiação/métodos , Dosimetria Termoluminescente/métodos , Contagem Corporal Total/métodos , Humanos , Doses de Radiação , Monitoramento de Radiação/instrumentação , Dosimetria Termoluminescente/instrumentação
18.
Phys Med Biol ; 63(8): 085017, 2018 04 19.
Artigo em Inglês | MEDLINE | ID: mdl-29509148

RESUMO

Systematic 3D mapping of out-of-field doses induced by a therapeutic proton pencil scanning beam in a 300 × 300 × 600 mm3 water phantom was performed using a set of thermoluminescence detectors (TLDs): MTS-7 (7LiF:Mg,Ti), MTS-6 (6LiF:Mg,Ti), MTS-N (natLiF:Mg,Ti) and TLD-700 (7LiF:Mg,Ti), radiophotoluminescent (RPL) detectors GD-352M and GD-302M, and polyallyldiglycol carbonate (PADC)-based (C12H18O7) track-etched detectors. Neutron and gamma-ray doses, as well as linear energy transfer distributions, were experimentally determined at 200 points within the phantom. In parallel, the Geant4 Monte Carlo code was applied to calculate neutron and gamma radiation spectra at the position of each detector. For the cubic proton target volume of 100 × 100 × 100 mm3 (spread out Bragg peak with a modulation of 100 mm) the scattered photon doses along the main axis of the phantom perpendicular to the primary beam were approximately 0.5 mGy Gy-1 at a distance of 100 mm and 0.02 mGy Gy-1 at 300 mm from the center of the target. For the neutrons, the corresponding values of dose equivalent were found to be ~0.7 and ~0.06 mSv Gy-1, respectively. The measured neutron doses were comparable with the out-of-field neutron doses from a similar experiment with 20 MV x-rays, whereas photon doses for the scanning proton beam were up to three orders of magnitude lower.


Assuntos
Imageamento Tridimensional/métodos , Imagens de Fantasmas , Terapia com Prótons/métodos , Radiometria/métodos , Dosimetria Termoluminescente/métodos , Raios gama , Humanos , Método de Monte Carlo , Nêutrons , Fótons , Prótons , Radioatividade , Cintilografia , Dosagem Radioterapêutica , Planejamento da Radioterapia Assistida por Computador/métodos , Dosimetria Termoluminescente/instrumentação , Água
19.
Health Phys ; 114(5): 543-548, 2018 05.
Artigo em Inglês | MEDLINE | ID: mdl-29578903

RESUMO

The U.S. Navy uses the Harshaw 8840/8841 dosimetric (DT-702/PD) system, which employs LiF:Mg,Cu,P thermoluminescent dosimeters (TLDs), developed and produced by Thermo Fisher Scientific (TFS). The dosimeter consists of four LiF:Mg,Cu,P elements, mounted in Teflon® on an aluminum card and placed in a plastic holder. The holder contains a unique filter for each chip made of copper, acrylonitrile butadiene styrene (ABS), Mylar®, and tin. For accredited dosimetry labs, the ISO/IEC 17025:2005(E) requires an acceptance procedure for all new equipment. The Naval Dosimetry Center (NDC) has developed and tested a new non-destructive procedure, which enables the verification and the evaluation of embedded filters in the holders. Testing is based on attenuation measurements of low-energy radiation transmitted through each filter in a representative sample group of holders to verify that the correct filter type and thickness are present. The measured response ratios are then compared with the expected response ratios. In addition, each element's measured response is compared to the mean response of the group. The test was designed and tested to identify significant nonconformities, such as missing copper or tin filters, double copper or double tin filters, or other nonconformities that may impact TLD response ratios. During the implementation of the developed procedure, testing revealed a holder with a double copper filter. To complete the evaluation, the impact of the nonconformities on proficiency testing was examined. The evaluation revealed failures in proficiency testing categories III and IV when these dosimeters were irradiated to high-energy betas.


Assuntos
Exposição Ocupacional/análise , Dosímetros de Radiação/normas , Proteção Radiológica/instrumentação , Avaliação da Tecnologia Biomédica/métodos , Dosimetria Termoluminescente/métodos , Calibragem , Desenho de Equipamento , Humanos , Militares , Doses de Radiação , Avaliação da Tecnologia Biomédica/normas , Dosimetria Termoluminescente/instrumentação , Dosimetria Termoluminescente/normas , Estados Unidos
20.
Appl Radiat Isot ; 137: 73-79, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-29587162

RESUMO

TLD-400 (CaF2:Mn) chips were applied for the gamma-ray dose measurement in a PMMA phantom exposed to a BNCT beam because of their very low neutron sensitivity. Since TLD-400 chips possess an adequate amount of Mn activator they have been employed in this work simultaneously for neuron activation measurement. The self-irradiation TL signals owing to the decay of the neutron induced 56Mn activity have been applied for a calibration of the TLD-400 chip in situ, where the activities were measured by an HPGe detector system and the energy deposition per disintegration of 56Mn was calculated by applying a Monte Carlo code. It was accidentally found that the irradiated TLD-400 chips were capable of emitting prominent scintillation lights owing to the induced 56Mn activity, which can easily be recorded by the TLD reader without heating and after a calibration can be used to determine the 56Mn activity.


Assuntos
Terapia por Captura de Nêutron de Boro , Dosimetria Termoluminescente/métodos , Terapia por Captura de Nêutron de Boro/normas , Calibragem , Raios gama , Humanos , Manganês/análise , Manganês/efeitos da radiação , Método de Monte Carlo , Nêutrons , Imagens de Fantasmas , Controle de Qualidade , Radioisótopos/análise , Dosagem Radioterapêutica , Contagem de Cintilação , Dosimetria Termoluminescente/instrumentação , Dosimetria Termoluminescente/estatística & dados numéricos
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