Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 79
Filtrar
Mais filtros

Tipo de documento
Intervalo de ano de publicação
1.
Nutrients ; 13(12)2021 Nov 26.
Artigo em Inglês | MEDLINE | ID: mdl-34959798

RESUMO

Reduced Glycemic Index (GI) of breakfast has been linked to improved cognitive performance in both children and adult populations across the morning. However, few studies have profiled the post-prandial glycemic response (PPGR) in younger children. The aim of this study was to assess PPGR to breakfast interventions differing in GI in healthy children aged 5-7 years. Eleven subjects completed an open-label, randomized, cross-over trial, receiving three equicaloric test beverages (260 kcal) consisting of 125 mL semi-skimmed milk and 50 g sugar (either glucose, sucrose, or isomaltulose). On a fourth occasion, the sucrose beverage was delivered as intermittent supply. PPGR was measured over 180 min using Continuous Glucose Monitoring (CGM). The incremental area under the curve (3h-iAUC) was highest for the glucose beverage, followed by intermittent sucrose (-21%, p = 0.288), sucrose (-27%, p = 0.139), and isomaltulose (-48%, p = 0.018). The isomaltulose beverage induced the smallest Cmax (7.8 mmol/L vs. >9.2 mmol/L for others) and the longest duration with moderate glucose level, between baseline value and 7.8 mmol/L (150 vs. <115 min for others). These results confirm that substituting mid-high GI sugars (e.g., sucrose and glucose) with low GI sugars (e.g., isomaltulose) during breakfast are a viable strategy for sustained energy release and glycemic response during the morning even in younger children.


Assuntos
Desjejum/fisiologia , Índice Glicêmico/fisiologia , Leite/química , Estudantes/estatística & dados numéricos , Edulcorantes/administração & dosagem , Animais , Área Sob a Curva , Glicemia/efeitos dos fármacos , Automonitorização da Glicemia , Criança , Pré-Escolar , Estudos Cross-Over , Sacarose Alimentar/administração & dosagem , Metabolismo Energético/efeitos dos fármacos , Feminino , Glucose/administração & dosagem , Voluntários Saudáveis , Humanos , Isomaltose/administração & dosagem , Isomaltose/análogos & derivados , Masculino , Período Pós-Prandial
2.
Life Sci ; 279: 119677, 2021 Aug 15.
Artigo em Inglês | MEDLINE | ID: mdl-34081990

RESUMO

AIMS: Pancreastatin (PST) is a crucial bioactive peptide derived from chromogranin A (CHGA) proprotein that exhibits an anti-insulin effect on adipocytes. Herein, we investigated the effects of PST on brown adipose tissues (BAT) and white adipose tissue (WAT) in connection with uncoupling protein-1 (UCP-1) regulated energy expenditure in high fructose diet (HFrD) fed and vinylcyclohexenediepoxide (VCD) induced perimenopausal rats. MATERIAL AND METHODS: We administered VCD in rats for 17 consecutive days and fed HFrd for 12 weeks. After 12 weeks estradiol and progesterone levels were detected. Furthermore, detection of glucose tolerance, insulin sensitivity, and body composition revealed impaired glucose homeostasis and enhanced PST levels. Effects of enhanced PST on UCP-1 level in BAT and WAT of perimenopausal rats were further investigated. KEY FINDINGS: Reduced serum estradiol, progesterone, and attenuated insulin response confirmed perimenopausal model development. Furthermore, enhanced PST serum level and its increased expression in BAT and WAT downregulated the UCP-1 expression. Subsequently, impaired ATP level, NADP/NADPH ratio, citrate synthase activity, enhanced mitochondrial reactive oxygen species (ROS) generation and perturbed mitochondrial membrane potential, further exacerbated mitochondrial dysfunction, cellular ROS production, and promoted apoptosis. Interestingly, PST inhibition by PST inhibitor peptide-8 (PSTi8) displayed a favorable impact on UCP-1 and energy expenditure. SIGNIFICANCE: The aforementioned outcomes indicated the substantial role of PST in altering the UCP-1 expression and associated energy homeostasis. Hence our results corroborate novel avenues to unravel the quest deciphering PST's role in energy homeostasis and its association with perimenopause.


Assuntos
Tecido Adiposo Marrom/efeitos dos fármacos , Tecido Adiposo Branco/efeitos dos fármacos , Cromogranina A/farmacologia , Metabolismo Energético , Frutose/administração & dosagem , Regulação da Expressão Gênica/efeitos dos fármacos , Proteína Desacopladora 1/metabolismo , Tecido Adiposo Marrom/metabolismo , Tecido Adiposo Branco/metabolismo , Animais , Feminino , Resistência à Insulina , Menopausa , Ratos , Ratos Sprague-Dawley , Edulcorantes/administração & dosagem , Proteína Desacopladora 1/genética
3.
J Pediatr ; 231: 74-80, 2021 04.
Artigo em Inglês | MEDLINE | ID: mdl-33338495

RESUMO

OBJECTIVE: To determine associations between a graded approach to intravenous (IV) dextrose treatment for neonatal hypoglycemia and changes in blood glucose (BG), length of stay (LOS), and cost of care. STUDY DESIGN: Retrospective cohort study of 277 infants born at ≥35 weeks of gestation in an urban academic delivery hospital, comparing the change in BG after IV dextrose initiation, neonatal intensive care unit (NICU) LOS, and cost of care in epochs before and after a hospital protocol change. During epoch 1, all infants who needed IV dextrose for hypoglycemia were given a bolus and started on IV dextrose at 60 mL/kg/day. During epoch 2, infants received IV dextrose at 30 or 60 mL/kg/day based on the degree of hypoglycemia. Differences in BG outcomes, LOS, and cost of hospital care between epochs were compared using adjusted median regression. RESULTS: In epoch 2, the median (IQR) rise in BG after initiating IV dextrose (19 [10, 31] mg/dL) was significantly lower than in epoch 1 (24 [14,37] mg/dL; adjusted ß = -6.0 mg/dL, 95% CI -11.2, -0.8). Time to normoglycemia did not differ significantly between epochs. NICU days decreased from a median (IQR) of 4.5 (2.1, 11.0) to 3.0 (1.5, 6.5) (adjusted ß = -1.9, 95% CI -3.0, -0.7). Costs associated with NICU hospitalization decreased from a median (IQR) $14 030 ($5847, $30 753) to $8470 ($5650, $19 019) (adjusted ß = -$4417, 95% CI -$571, -$8263) after guideline implementation. CONCLUSIONS: A graded approach to IV dextrose was associated with decreased BG lability and length and cost of NICU stay for infants with neonatal hypoglycemia.


Assuntos
Glicemia/metabolismo , Glucose/administração & dosagem , Custos Hospitalares/estatística & dados numéricos , Hipoglicemia/tratamento farmacológico , Unidades de Terapia Intensiva Neonatal/estatística & dados numéricos , Tempo de Internação/estatística & dados numéricos , Edulcorantes/administração & dosagem , Administração Intravenosa , Biomarcadores/sangue , Boston , Esquema de Medicação , Feminino , Glucose/economia , Glucose/uso terapêutico , Humanos , Hipoglicemia/sangue , Hipoglicemia/diagnóstico , Hipoglicemia/economia , Recém-Nascido , Unidades de Terapia Intensiva Neonatal/economia , Tempo de Internação/economia , Masculino , Estudos Retrospectivos , Edulcorantes/economia , Edulcorantes/uso terapêutico , Resultado do Tratamento
4.
J Pediatr ; 226: 80-86.e1, 2020 11.
Artigo em Inglês | MEDLINE | ID: mdl-32634402

RESUMO

OBJECTIVE: To evaluate the long-term costs and impact on quality of life of using prophylactic dextrose gel in patients at increased risk of developing neonatal hypoglycemia. STUDY DESIGN: A cost-utility analysis was performed from the perspective of the health system, using a decision tree to model the long-term clinical outcomes of neonatal hypoglycemia, including cerebral palsy, epilepsy, vision disturbances, and learning disabilities, in patients at increased risk of neonatal hypoglycemia who received prophylactic dextrose gel vs standard care. Model parameters including likelihoods of hypoglycemia and admission to a neonatal intensive care unit, were based on the pre-Hypoglycemia Prevention with Oral Dextrose Study. Estimations of the likelihood of long-term condition(s), and their costs, were based on review of published literature. RESULTS: Patients who received prophylactic dextrose gel incurred costs to the health system of around US $14 000 over an 18-year time horizon, accruing 11.25 quality-adjusted life-years, whereas those who did not receive prophylactic treatment incurred cost of around $16 000 and experienced a utility of 11.10 quality-adjusted life-years. CONCLUSIONS: A prophylactic strategy of using dextrose gel in infants at increased risk of neonatal hypoglycemia is likely to be cost effective compared with standard care, to reduce the direct costs to the health system over an 18-year time horizon, and improve quality of life.


Assuntos
Glucose/administração & dosagem , Custos de Cuidados de Saúde , Hipoglicemia/economia , Hipoglicemia/prevenção & controle , Edulcorantes/administração & dosagem , Administração Oral , Árvores de Decisões , Feminino , Géis , Glucose/economia , Humanos , Hipoglicemia/epidemiologia , Recém-Nascido , Masculino , Anos de Vida Ajustados por Qualidade de Vida , Fatores de Risco , Edulcorantes/economia
5.
Psychopharmacology (Berl) ; 237(5): 1447-1457, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-31993695

RESUMO

RATIONALE: In a previous study, investigating choice between heroin and a non-drug alternative in animals and reductions in income (i.e., choices/day) caused the percentage of income spent on heroin to progressively decrease. In contrast, another study found that humans with opioid use disorder spent the majority of their income on heroin even though they had little income. Comparison of these two studies suggests that the seemingly conflicting results could be explained by differences in the underlying economy types of the choice alternatives. OBJECTIVE: The present experiment tested the hypothesis that the effect of income changes on choice between heroin and a non-drug alternative depends on economy type. METHODS: Rats chose between heroin and saccharin under three income levels. For the Closed group, the choice session was the only opportunity to obtain these reinforcers. For the Heroin Open group and the Saccharin Open group, choice sessions were followed by 3-h periods of unlimited access to heroin or saccharin, respectively. RESULTS: As income decreased, the Closed and Heroin Open groups, but not the Saccharin Open group, spent an increasingly greater percentage of income on saccharin than on heroin. The Saccharin Open group, compared to the other groups, spent a greater percentage of income on heroin as income decreased. CONCLUSIONS: Results confirm that the effects of income and economy type can interact and this may explain the apparently discrepant results of earlier studies. More generally, findings suggest that situations where heroin choice has little consequence for consumption of non-drug alternatives may promote heroin use.


Assuntos
Comportamento Aditivo/psicologia , Comportamento de Escolha/efeitos dos fármacos , Heroína/administração & dosagem , Sacarina/administração & dosagem , Analgésicos Opioides/administração & dosagem , Animais , Comportamento de Escolha/fisiologia , Masculino , Ratos , Ratos Long-Evans , Autoadministração , Edulcorantes/administração & dosagem
6.
Am J Emerg Med ; 38(3): 598-602, 2020 03.
Artigo em Inglês | MEDLINE | ID: mdl-31837905

RESUMO

INTRODUCTION: Hypoglycemia is a common adverse effect when intravenous (IV) insulin is administered for hyperkalemia. A prolonged infusion of dextrose 10% (D10) may mitigate hypoglycemia compared to dextrose 50% (D50) bolus. Our objective was to evaluate whether D10 infusion is a safe and effective alternative to D50 bolus for hypoglycemia prevention in hyperkalemic patients receiving IV insulin. METHODS: We conducted a retrospective review of patients ≥ 18 years who presented to the emergency department (ED) with hyperkalemia (K+ > 5.5) and received IV insulin and D10 infusion or D50 bolus within 3 h. The primary endpoint was incidence of hypoglycemia, defined as blood glucose (BG) ≤ 70 mg/dL, in the 24 h following IV insulin administration for hyperkalemia. RESULTS: A total of 134 patients were included; 72 in the D50 group and 62 in the D10 group. There was no difference in incidence of hypoglycemia between the D50 and D10 groups (16 [22%] vs. 16 [26%], p = 0.77). Symptomatic hypoglycemia, severe hypoglycemia, and hyperglycemia rates in the D50 and D10 groups were [5 (7%) vs. 2 (3%), p = 0.45], [5 (7%) vs. 1 (2%), p = 0.22], and [34 (47%) vs. 23 (37%), p = 0.31] respectively. Low initial BG was a predictor for developing hypoglycemia. CONCLUSIONS: In our study, D10 infusions appeared to be at least as effective as D50 bolus in preventing hypoglycemia in hyperkalemic patients receiving IV insulin. In context of ongoing D50 injection shortages, D10 infusions should be a therapeutic strategy in this patient population.


Assuntos
Glicemia/metabolismo , Gerenciamento Clínico , Serviço Hospitalar de Emergência , Glucose/administração & dosagem , Hiperpotassemia/tratamento farmacológico , Insulina/sangue , Idoso , Relação Dose-Resposta a Droga , Feminino , Humanos , Hiperpotassemia/sangue , Incidência , Infusões Intravenosas , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Edulcorantes/administração & dosagem , Resultado do Tratamento , Estados Unidos/epidemiologia
7.
Nutrients ; 11(2)2019 Feb 21.
Artigo em Inglês | MEDLINE | ID: mdl-30795633

RESUMO

This cross-sectional study assessed sugar-sweetened beverage (SSB) consumption and its associations with the sociodemographic and physical characteristics, behavior and knowledge of New Caledonian adolescents. The survey data of 447 adolescents from ages 11 to 16 years were collected in five secondary public schools of New Caledonia between July 2015 and April 2016. These data included measured height and weight, SSB consumption, sociodemographic characteristics, body weight perception, physical activity, and knowledge (sugar quantity/SSB unit; energy expenditure required to eliminate a unit) and opinions about the SSB‒weight gain relationship. Ninety percent of these adolescents declared regularly drinking SSBs. Quantities were associated with living environment (1.94 L·week-1 in urban environment vs. 4.49 L·week-1 in rural environment, p = 0.001), ethnic community (4.77 L·week-1 in Melanesians vs. 2.46 L·week-1 in Caucasians, p < 0.001) and knowledge about energy expenditure (6.22 L·week-1 in unknowledgeable adolescents vs. 4.26 L·week-1 in adolescents who underestimated, 3.73 L·week-1 in adolescents who overestimated, and 3.64 L·week-1 in adolescents who correctly responded on the energy expenditure required to eliminate an SSB unit, p = 0.033). To conclude, community-based health promotion strategies should (1) focus on the physical effort needed to negate SSB consumption rather than the nutritional energy from SSB units and (2) highlight how to achieve sustainable lifestyles and provide tools for greater understanding and positive action.


Assuntos
Bebidas , Dieta , Açúcares da Dieta/administração & dosagem , Comportamento Alimentar , Edulcorantes/administração & dosagem , Adolescente , Criança , Estudos Transversais , Dieta/etnologia , Ingestão de Energia , Exercício Físico , Feminino , Comportamentos Relacionados com a Saúde , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Estilo de Vida , Masculino , Havaiano Nativo ou Outro Ilhéu do Pacífico , Nova Caledônia , População Rural , Instituições Acadêmicas , Inquéritos e Questionários , População Urbana , População Branca
8.
Int J Behav Nutr Phys Act ; 16(1): 13, 2019 01 30.
Artigo em Inglês | MEDLINE | ID: mdl-30700311

RESUMO

BACKGROUND: The World Health Organization has advocated for sugar-sweetened beverage (SSB) taxes as part of a broader non-communicable disease prevention strategy, and these taxes have been recently introduced in a wide range of settings. However, much is still unknown about how SSB taxes operate in various contexts and as a result of different tax designs. In 2015, the Government of Barbados implemented a 10% ad valorem (value-based) tax on SSBs. It has been hypothesized that this tax structure may inadvertently encourage consumers to switch to cheaper sugary drinks. We aimed to assess whether and to what extent there has been a change in sales of SSBs following implementation of the SSB tax. METHODS: We used electronic point of sale data from a major grocery store chain and applied an interrupted time series (ITS) design to assess grocery store SSB and non-SSB sales from January 2013 to October 2016. We controlled for the underlying time trend, seasonality, inflation, tourism and holidays. We conducted sensitivity analyses using a cross-country control (Trinidad and Tobago) and a within-country control (vinegar). We included a post-hoc stratification by price tertile to assess the extent to which consumers may switch to cheaper sugary drinks. RESULTS: We found that average weekly sales of SSBs decreased by 4.3% (95%CI 3.6 to 4.9%) compared to expected sales without a tax, primarily driven by a decrease in carbonated SSBs sales of 3.6% (95%CI 2.9 to 4.4%). Sales of non-SSBs increased by 5.2% (95%CI 4.5 to 5.9%), with bottled water sales increasing by an average of 7.5% (95%CI 6.5 to 8.3%). The sensitivity analyses were consistent with the uncontrolled results. After stratifying by price, we found evidence of substitution to cheaper SSBs. CONCLUSIONS: This study suggests that the Barbados SSB tax was associated with decreased sales of SSBs in a major grocery store chain after controlling for underlying trends. This finding was robust to sensitivity analyses. We found evidence to suggest that consumers may have changed their behaviour in response to the tax by purchasing cheaper sugary drinks, in addition to substituting to untaxed products. This has important implications for the design of future SSB taxes.


Assuntos
Bebidas/economia , Comércio , Comportamento do Consumidor , Açúcares da Dieta/economia , Preferências Alimentares , Edulcorantes/economia , Impostos , Adulto , Barbados , Dieta/economia , Açúcares da Dieta/administração & dosagem , Humanos , Açúcares , Edulcorantes/administração & dosagem
9.
Addict Biol ; 24(1): 65-75, 2019 01.
Artigo em Inglês | MEDLINE | ID: mdl-29178664

RESUMO

Rats raised in an enriched condition (EC) show decreased stimulant self-administration relative to rats reared in an isolated condition (IC). However, few studies have examined the behavioral mechanisms underlying this environment-induced difference in self-administration. Because economic demand for drugs of abuse predicts addiction-like behavior in both humans and animals, we applied a behavioral economic analysis to cocaine self-administration data in EC and IC rats. During cocaine self-administration, the dose decreased across blocks of trials (0.75-0.003 mg/kg/inf), which allowed for a determination of demand intensity and demand elasticity. Demand intensity did not differ between EC and IC rats; however, cocaine was more elastic in EC rats relative to IC rats (i.e. EC rats were less willing to respond for cocaine as the unit price increased). When EC rats were placed in an isolated condition, demand elasticity decreased, whereas elasticity increased for IC rats placed in an enriched condition. Additionally, we applied behavioral economic analyses to previously published self-administration data and found that our results replicate past findings with cocaine and methylphenidate. To determine if differences in demand elasticity are specific to drug reinforcement, a separate group of rats was tested in sucrose or saccharin self-administration. Results showed that sucrose and saccharin were more elastic in EC rats relative to IC rats, and demand intensity was lower for saccharin in EC rats relative to IC rats. Overall, drug and nondrug reinforcers are more elastic in EC rats, which may account for the protective effects of environmental enrichment against stimulant self-administration.


Assuntos
Cocaína/administração & dosagem , Inibidores da Captação de Dopamina/administração & dosagem , Sacarina/administração & dosagem , Meio Social , Isolamento Social , Sacarose/administração & dosagem , Edulcorantes/administração & dosagem , Animais , Economia Comportamental , Masculino , Ratos , Ratos Sprague-Dawley , Autoadministração
10.
Prev Med ; 118: 16-22, 2019 01.
Artigo em Inglês | MEDLINE | ID: mdl-30287330

RESUMO

In 2014, an 8% tax on energy-dense nutrient-poor foods was implemented in Mexico with the aim of reducing its consumption. This paper estimated changes in household purchases of taxed food. We used the latest five waves of the nationally representative Mexican Income and Expenditure Survey (2008, 2010, 2012, 2014 and 2016). The analytic sample comprises 154,777 households. We estimated changes in purchases based on a before and after comparison. Results show a reduction in purchases of taxed food of -5.4 g/week per capita, equivalent to a relative reduction of -5.3% in the 2014 and 2016 waves compared to the 2008, 2010 and 2012 rounds. The largest relative reductions were in urban areas (-6.9%), among households with children (-7.0%), households where the head had an intermediate educational level (-9.9%) and the southern region (-14.8%). We did not find a significant reduction in rural areas. While there is a large heterogeneity, the fiscal instrument has been effective in reducing taxed food purchases and has generated substantial revenue that could be used to finance policies for the prevention and treatment of obesity.


Assuntos
Comércio/estatística & dados numéricos , Comportamento do Consumidor/economia , Ingestão de Energia , Características da Família , Alimentos/economia , Impostos/economia , Adolescente , Adulto , Pão/estatística & dados numéricos , Doces/estatística & dados numéricos , Criança , Pré-Escolar , Comércio/tendências , Feminino , Alimentos/estatística & dados numéricos , Humanos , Renda/estatística & dados numéricos , Lactente , Masculino , México , Nutrientes , Obesidade/prevenção & controle , Inquéritos e Questionários , Edulcorantes/administração & dosagem , Edulcorantes/economia , Impostos/legislação & jurisprudência
11.
Prev Chronic Dis ; 15: E154, 2018 12 13.
Artigo em Inglês | MEDLINE | ID: mdl-30576280

RESUMO

We examined associations between sugar-sweetened beverage (SSB) intake - a chronic disease risk factor - and characteristics of 75,029 adults (≥18 y) in 9 states by using 2016 Behavioral Risk Factor Surveillance System (BRFSS) data. We used multinomial logistic regression to estimate adjusted odds ratios for SSB intake categorized as none (reference), fewer than 1 time per day, and 1 or more times per day, by sociodemographic and behavioral characteristics. Overall, 32.1% of respondents drank SSBs 1 or more times per day. We found higher odds for 1 or more times per day among younger respondents, men, Hispanic and non-Hispanic black respondents, current smokers, respondents residing in nonmetropolitan counties, employed respondents, and those with less than high school education, obesity, and no physical activity. Our findings can inform the targeting of efforts to reduce SSB consumption.


Assuntos
Bebidas/estatística & dados numéricos , Sacarose Alimentar/administração & dosagem , Edulcorantes/administração & dosagem , Adolescente , Adulto , Distribuição por Idade , Sistema de Vigilância de Fator de Risco Comportamental , Sacarose Alimentar/efeitos adversos , Feminino , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Obesidade/epidemiologia , Distribuição por Sexo , Fatores Socioeconômicos , Açúcares , Edulcorantes/efeitos adversos , Estados Unidos/epidemiologia , Adulto Jovem
12.
Nutr Hosp ; 35(6): 1379-1386, 2018 Dec 03.
Artigo em Inglês | MEDLINE | ID: mdl-30525853

RESUMO

BACKGROUND: food insecurity occurs when quality and quantity of food is insufficient for maintaining healthy nutritional and food profiles. OBJECTIVES: to determine if food insecurity is associated with dietary and biochemical measures in mothers of the northwest of Mexico, which relies primarily on fisheries for livelihood. METHODS: a cross-sectional study was conducted with 116 mothers of the Northwest of Mexico. A socioeconomic survey, food security scale, andtwo non-consecutive 24-hour recalls were applied. Anthropometric  measurements were made and hemoglobin, glucose and cholesterol levelswere measured. The association between key measures and food insecurity was assessed using logistic and linear regression. RESULTS: two-thirds (68%) of households experienced food insecurity. Mothers with mild insecurity had 3.7 and 3.2 times higher odds of not consuming fruits and vegetables, respectively, and 4.9 times higher odds of consuming sweetened non-dairy drinks (p = 0.04; 0.04 and 0.05, respectively). In addition, they consumed less protein (ß = -3.22%; p < 0.01) and more carbohydrates (ß = 6.04%; p = 0.02) compared with mothers with food security. Mothers with severe insecurity consumed less iodine (ß = -24.41 µg; p = 0.03) and had lower levels of HDL cholesterol (ß = -12.01 mg/dl; p = 0.03) than mothers with food security. CONCLUSIONS: food insecurity was associated with low quality diet and low levels of HDL cholesterol in mothers of Northwest Mexico relying on fisheries for livelihood.


Assuntos
HDL-Colesterol/sangue , Dieta , Emprego/estatística & dados numéricos , Pesqueiros/economia , Abastecimento de Alimentos/estatística & dados numéricos , Mães , Adulto , Bebidas/análise , Estudos Transversais , Carboidratos da Dieta/administração & dosagem , Emprego/economia , Feminino , Qualidade dos Alimentos , Frutas , Humanos , México , Fatores Socioeconômicos , Edulcorantes/administração & dosagem , Edulcorantes/análise , Verduras
13.
Am J Clin Nutr ; 108(3): 548-563, 2018 09 01.
Artigo em Inglês | MEDLINE | ID: mdl-30535085

RESUMO

Background: Obesity has a serious impact on public health. Sugar-sweetened beverages (SSBs) are implicated in the obesity epidemic. Regulation has been suggested as one approach to limit consumption. Objective: The aim of this study was to synthesize existing evidence related to the impact of taxes on the consumption, purchase, or sales of SSBs. Design: A systematic review was conducted by using MEDLINE through PubMed (https://www.ncbi.nlm.nih.gov/pubmed), the Cochrane Library (http://www.cochranelibrary.com/), the Web of Science (https://login.webofknowledge.com/error/Error?PathInfo=%2F&Error=IPError), and Scopus (https://www.scopus.com/search/form.uri?display=basic) in the period 2011-2017 for studies that analyzed the impact of fiscal regulatory measures on the consumption, purchase, or sales of SSBs. The quality of evidence was assessed according to the CONSORT (Consolidated Standards of Reporting Trials) and the TREND (Transparent Reporting of Evaluations with Nonrandomized Designs) statements. Results: Of the 17 studies, 5 (29.4%) evaluated the impact of a tax on SSBs in naturalistic experiments by county or city in the United States and in Mexico. Findings indicated that purchases or sales of SSBs decreased significantly with taxation amounts of 8% (Berkeley, CA) and 10% (Mexico). One study found no effect on sales of SSBs in 2 states that enacted a 5.5% tax on sodas. Twelve (70.6%) studies were based on virtual or experimental conditions evaluating either purchasing behavior or sales (6 studies; 50.0%) or behavioral intent (6 studies; 50.0%), resulting in a decrease in either purchasing behavior or sales or intent behavior with heterogeneity according to the tax rate. Conclusions: Taxation significantly influences planned purchases and increases the probability of the purchase of healthy beverages. SSB taxes have the potential to reduce calorie and sugar intake, but further research is needed to evaluate effects on diet quality.


Assuntos
Bebidas/economia , Edulcorantes/economia , Impostos/economia , Impostos/legislação & jurisprudência , Adolescente , Adulto , Comércio/estatística & dados numéricos , Comportamento do Consumidor/economia , Sacarose Alimentar , Ingestão de Energia , Feminino , Promoção da Saúde/legislação & jurisprudência , Humanos , MEDLINE , México/epidemiologia , Obesidade/epidemiologia , Obesidade/etiologia , Obesidade/prevenção & controle , Classe Social , Inquéritos e Questionários , Edulcorantes/administração & dosagem , Edulcorantes/efeitos adversos , Estados Unidos/epidemiologia , Adulto Jovem
14.
Public Health Nutr ; 21(18): 3307-3317, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-30207262

RESUMO

OBJECTIVE: To analyse trends in sweetened beverages consumption among adults in Brazil between 2007 and 2016. DESIGN: A time-series analysis, with data from the Surveillance System of Risk and Protection Factors for Chronic Diseases by Telephone Survey (VIGITEL). The prevalence of regular consumption (≥5 d/week), the average daily consumption (millilitres) and the prevalence of non-consumption of these beverages were analysed. The temporal variations of the indicators were calculated by linear regression. The analyses were performed for the complete set of the evaluated population and stratified by sociodemographic characteristics. SETTING: Brazilian capitals and Federal District. SUBJECTS: Brazilian adults aged ≥18 years (n 519 641). RESULTS: There was a reduction in both regular and average daily consumption of sugar- and artificially sweetened beverages (-1·28 percentage points (pp)/year, P=0·001 and -9·63 ml/year, P=0·001, respectively). The same result regarding regular consumption was found when only sugar-sweetened beverages were analysed (-1·11 pp/year, P=0·011). Similar trends were identified in the stratified analyses, with a greater magnitude of reduction among males, young adults, those with higher schooling and residents of more developed regions. Coincidentally, there was an increase in the prevalence of adults who did not consume sweetened beverages (1·54 pp/year, P=0·005). CONCLUSIONS: The consumption of sweetened beverages decreased during the period. However, a significant portion of the population still referred a daily consumption of these beverages.


Assuntos
Bebidas/estatística & dados numéricos , Dieta/tendências , Sacarose Alimentar/administração & dosagem , Ingestão de Energia , Edulcorantes/administração & dosagem , Adulto , Idoso , Brasil , Feminino , Humanos , Entrevistas como Assunto , Masculino , Pessoa de Meia-Idade , Fatores Socioeconômicos
15.
Am J Prev Med ; 55(1): 26-34, 2018 07.
Artigo em Inglês | MEDLINE | ID: mdl-29656917

RESUMO

INTRODUCTION: On January 1, 2017, Philadelphia implemented a beverage tax of $0.015/ounce on sugar ("regular") and sugar-substitute ("diet") beverages. The purpose of this study was to evaluate the immediate impact of the tax on residents' consumption of soda, fruit drinks, energy drinks, and bottled water. METHODS: A repeat cross-sectional study design used data from a random-digit-dialing phone survey during a no-tax period (December 6-31, 2016) and a tax period (January 15-February 31, 2017) among 899 respondents in Philadelphia, Pennsylvania, and 878 respondents in three nearby comparison cities. Survey questions included frequency and volume of bottled water and beverages. Outcomes were daily consumption, and 30-day consumption frequency and volume. Propensity score-weighted difference-in-differences regression was used to control for secular time trend and confounding. Covariates were sociodemographics, BMI, health status, smoking, and alcohol use. Analyses were conducted in 2017. RESULTS: Within the first 2 months of tax implementation, relative to the comparison cities, in Philadelphia the odds of daily consumption of regular soda was 40% lower (OR=0.6, 95% CI=0.37, 0.97); energy drink was 64% lower (OR=0.36, 95% CI=0.17, 0.76); bottled water was 58% higher (OR=1.58, 95% CI=1.13, 2.20); and the 30-day regular soda consumption frequency was 38% lower (ratio of consumption frequency=0.62, 95% CI=0.40, 0.98). CONCLUSIONS: Early results suggest that the tax influenced daily consumption of regular soda, energy drinks, and bottled water. Future studies are needed to evaluate longer-term impact of the tax on sugared beverage consumption and substitutions.


Assuntos
Bebidas/estatística & dados numéricos , Água Potável , Comportamento Alimentar , Impostos/estatística & dados numéricos , Adulto , Bebidas Gaseificadas/estatística & dados numéricos , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Philadelphia , Edulcorantes/administração & dosagem , Impostos/economia , Adulto Jovem
16.
Int J Behav Nutr Phys Act ; 15(1): 8, 2018 01 17.
Artigo em Inglês | MEDLINE | ID: mdl-29343247

RESUMO

BACKGROUND: In Norway, social inequalities in health and health-related behaviors have been reported despite the well-developed welfare state. The objective of the present study was to analyze; (i) the development in frequency of consumption of sugar-sweetened beverages (SSB) and artificially sweetened beverages (ASB) from childhood to adulthood; (ii) socioeconomic inequalities in the consumption of SSB and ASB using different indicators of socioeconomic status (SES); (iii) time trends in potential disparities in SSB and ASB consumption among different socioeconomic groups to assess the development in socioeconomic inequality from childhood to adulthood. METHODS: This study uses data from the Fruits and Vegetables Make the Marks (FVMM) longitudinal cohort, including participants (n = 437) from 20 random schools from two Norwegian counties. Data from the first survey in 2001 (mean age 11.8) and follow-up surveys in 2005 (mean age 15.5) and 2016 (mean age 26.5) were used. Consumption of SSB and ASB were measured using a food frequency questionnaire, which the participants completed at school in 2001 and 2005, and online in 2016. Various indicators of SES were included; in 2001, parental education and income were measured, in 2005, participants' educational intentions in adolescence were measured, and in 2016, participants' own education and income were measured. The main analyses conducted were linear mixed effects analysis of the repeated measures. RESULTS: Between 2001 and 2016, a decrease in frequency of consumption of SSB (2.8 v 1.3 times/week; p = < 0.001) and an increase in frequency of consumption of ASB (1.1 v 1.6 times/week; p = 0.002) were observed. Participants with a higher educational level in adulthood and higher educational intentions in adolescence had a significantly lower frequency of consumption of SSB at all time points (2001, 2005 and 2016). No significant widening (or narrowing) of inequalities were observed from childhood to adulthood. CONCLUSIONS: A decrease in consumption of SSB and an increase in consumption of ASB from childhood to adulthood were found. Participants with high SES consumed in general less SSB (but not ASB), however, results varied depending on SES indicator used. The established inequalities persisted from childhood to adulthood.


Assuntos
Bebidas , Dieta , Açúcares da Dieta/administração & dosagem , Comportamento Alimentar , Adoçantes não Calóricos/administração & dosagem , Classe Social , Adolescente , Adulto , Bebidas/análise , Criança , Estudos de Coortes , Feminino , Seguimentos , Frutas , Humanos , Masculino , Noruega , Instituições Acadêmicas , Fatores Socioeconômicos , Açúcares/administração & dosagem , Inquéritos e Questionários , Edulcorantes/administração & dosagem , Verduras , Adulto Jovem
17.
Public Health Nutr ; 21(3): 618-626, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-29061203

RESUMO

OBJECTIVE: To explore awareness and perceptions of the sugar-sweetened beverage (SSB) tax implemented in Mexico in 2014 among a sample of Mexican adolescents, and to investigate how the tax has affected their purchases and intake of SSB. DESIGN: Qualitative. SETTING: Semi-structured interviews were conducted in April-May 2016. The data were analysed using thematic analysis. SUBJECTS: Adolescents residing in north-west Mexico (n 29, 55·2 % females), aged 15-19 years. RESULTS: Four main themes emerged: awareness of taxation; perceptions of how the tax has affected SSB intake; reasons why the tax was not perceived to have affected SSB intake; and preferences for substitution of the taxed SSB. Participants were mostly unaware of the tax and perceived that it would not cause reductions in their intake of SSB; they felt that the price increase was low and insufficient to affect intake. Taste preferences and 'addiction' to SSB were highlighted as the main reasons why participants perceived taxation would not affect intake. If SSB prices were to increase further via a higher tax, participants would consider substituting SSB with other beverages, namely home-made drinks (e.g. 100 % fruit juices), non-caloric, instant-flavoured drinks and water. CONCLUSIONS: These findings provide important insights into the views of this sample of Mexican adolescents regarding the taxation of SSB, by pointing out several possible limitations of the tax policy in Mexico. These results could inform the design of future interventions directed at Mexican youth that would complement and strengthen the current SSB taxation.


Assuntos
Atitude , Bebidas , Comportamento do Consumidor , Dieta , Açúcares da Dieta/administração & dosagem , Edulcorantes , Impostos , Adolescente , Adulto , Bebidas/economia , Comércio , Açúcares da Dieta/economia , Feminino , Preferências Alimentares , Promoção da Saúde/métodos , Humanos , Masculino , México , Política Pública , Pesquisa Qualitativa , Edulcorantes/administração & dosagem , Edulcorantes/economia , Adulto Jovem
18.
Acta Odontol Scand ; 76(2): 105-110, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29032715

RESUMO

OBJECTIVES: We aimed to investigate the habitual consumption of sugar-sweetened beverages (SSBs) and sweets in relation to mothers' behaviours and practices with their infants. METHODS: We targeted mothers with children 1-24 months (N = 200) visiting Public Child Health clinics in Finland. During routine visits mothers (N = 179) volunteered to complete a self-administered anonymous questionnaire about their child's health-related behaviours (consumption of sweets and SSBs, tooth brushing frequency). The questionnaires also included questions about the mothers' background (age, education) and health-related behaviours (consumption of sweets, tooth brushing frequency and smoking habits). The children were categorised by age, and Chi-squared tests, Fischer's exact test, ANOVA and correlation coefficient served for the statistical analyses. RESULTS: Of those under 6 months, almost half (44%) received SSBs, and 45% of them more than once a week. Their use gradually increased by age such that by 19-24 months, all received SSBs at least sometimes, and 56%, frequently. Fewer than half of the mothers (33-43%) gave sweets to their children between the ages of 10-15 months, but 92% by the age of 2 years. Children's twice-a-day tooth brushing increased from 14% to 33%. The child's age and tooth brushing frequency correlated with the consumption of sugar-sweetened products (r = 0.458). CONCLUSIONS: Infants frequent consumption of sugar-sweetened products begins early in childhood. Thus, tackling these common risk factors in the first years of life is essential and calls for health-promoting actions in multiple areas that target primarily the parents of infants.


Assuntos
Bebidas/efeitos adversos , Doces/efeitos adversos , Sacarose Alimentar/efeitos adversos , Edulcorantes/administração & dosagem , Fatores Etários , Criança , Fenômenos Fisiológicos da Nutrição Infantil , Sacarose Alimentar/administração & dosagem , Feminino , Finlândia , Promoção da Saúde , Humanos , Lactente , Masculino , Mães/educação , Pais , Inquéritos e Questionários , Edulcorantes/efeitos adversos , Escovação Dentária/estatística & dados numéricos
19.
Medwave ; 17(8): e7054, 2017 10 25.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-29099817

RESUMO

The high prevalence of obesity in Chile, along with the increasing consumption of sugary drinks in the country, has made apparent the need to propose fiscal measures, through taxes on specific foods, as a complementary alternative to approach this problem. Since 2014, an additional 5% increase in the tax on sugar-sweetened nonalcoholic beverages has been in effect in Chile, an amount that may be insufficient to produce an impact on obesity levels. The evidence of the effectiveness of fiscal measures upon sugary beverages, in terms of price modification, generally reflects a high transfer of the tax to the final consumers, which is variable according to local conditions. After the analysis of the literature, a sensitivity of the demand to the changes in prices of sugary drinks was evidenced, by means of negative elasticity close to -1, for different groups observed, besides a decrease in the consumption of these products. On the other hand, effects on body weight after the application of these taxes were analyzed by several simulation studies, reporting a decrease on prevalence of obesity between 0.99% and 2.4%. Within the acceptability of a fiscal measure of this nature, there were variable support figures between 36% and 60% among general population. Regarding possible negative effects on employment, an international study even evidenced a rise in the figures for employment in two locations following the application of a tax on sugary drinks. The research showed that there is evidence to support the implementation of a fiscal measure upon sugary beverages in Chile; however, there is a lack of local simulation studies to explore the possible effects and implications of a new tax of this kind in the country. Taxation measures upon foods seem to be both viable and effective alternatives to address the problem of obesity in Chile, but they should be considered as part of an overall strategy with the clear goal of reducing the prevalence of national obesity.


La alta prevalencia de obesidad en Chile en conjunto con el creciente consumo de bebidas azucaradas en el país, han permitido plantear las medidas fiscales por medio de los impuestos a alimentos específicos, como una alternativa complementaria de abordaje a este problema. Desde 2014 se encuentra en vigencia en Chile un alza adicional de 5% del impuesto a las bebidas analcohólicas azucaradas, magnitud eventualmente insuficiente para producir impacto en los niveles de obesidad. La evidencia de efectividad de las medidas fiscales a bebidas azucaradas en términos de modificación de precio, en general muestra un alto traspaso del impuesto al consumidor, lo que varía según condiciones locales. El análisis de la literatura, reveló una sensibilidad de la demanda a los cambios de precios de las bebidas azucaradas por medio de elasticidades negativas cercanas a -1 para distintos grupos observados, junto con la disminución en el consumo de estos productos. Por su parte, los efectos en peso corporal tras la aplicación de estos impuestos fueron analizados por diversos estudios de simulación. Éstos reportaron disminución de prevalencia de obesidad entre 0,99% y 2,4%. En relación a la aceptabilidad de una medida fiscal de esta naturaleza se presentaron cifras variables de apoyo entre 36 y 60% en población general. Respecto a los eventuales efectos negativos en empleos, un estudio internacional incluso demostró un alza en las cifras de empleo en dos estados tras la aplicación de un impuesto a bebidas azucaradas. La búsqueda bibliográfica demostró que existe evidencia para fundamentar la implementación de una medida fiscal a bebidas azucaradas en Chile. Sin embargo, faltan estudios de simulación locales que permitan explorar los eventuales efectos e implicancias de un nuevo impuesto de este tipo en el país. Las medidas fiscales a alimentos parecen ser alternativas viables y efectivas para abordar el problema de la obesidad en Chile, pero deben considerarse como parte de una estrategia integral, con el fin de lograr un impacto final en la disminución de prevalencia de obesidad en el país.


Assuntos
Bebidas/economia , Comércio/economia , Obesidade/prevenção & controle , Edulcorantes/economia , Chile , Política de Saúde , Humanos , Obesidade/economia , Prevalência , Edulcorantes/administração & dosagem , Impostos/economia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA