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2.
United European Gastroenterol J ; 8(6): 685-694, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-32628898

RESUMO

Obesity, type 2 diabetes mellitus (T2DM) and nonalcoholic steatohepatitis are increasing pandemic metabolic disorders. Lifestyle intervention (LSI) is the cornerstone treatment for these but is successful as standard care alone in only a few patients, given the modest weight loss at mid and long term. Conversely, bariatric surgery is the only proven effective treatment for these metabolic disorders, albeit offered only in a small percentage of cases because of its invasiveness and cost. The so-called endoscopic bariatric and metabolic therapies (EBMTs) include new, less-invasive technologies such as intragastric balloons, aspiration therapy, endoscopic sleeve gastroplasty, diversion devices, and duodenal mucosal resurfacing, currently at various stages of development. EBMTs, as an add-on to LSI, might represent an effective treatment filling the gap between medical and surgical management, taking into account, however, that obesity and its associated comorbidities constitute a chronic disease that needs lifelong therapy. In this review we describe the current scientific evidence surrounding EBMTs as well as future opportunities for such treatments in managing obesity and metabolic disorders.


Assuntos
Cirurgia Bariátrica/métodos , Diabetes Mellitus Tipo 2/cirurgia , Endoscopia do Sistema Digestório/métodos , Hepatopatia Gordurosa não Alcoólica/cirurgia , Obesidade/cirurgia , Cirurgia Bariátrica/efeitos adversos , Cirurgia Bariátrica/tendências , Doença Crônica/epidemiologia , Doença Crônica/terapia , Comorbidade , Diabetes Mellitus Tipo 2/epidemiologia , Diabetes Mellitus Tipo 2/metabolismo , Endoscopia , Endoscopia do Sistema Digestório/efeitos adversos , Endoscopia do Sistema Digestório/tendências , Carga Global da Doença , Humanos , Hepatopatia Gordurosa não Alcoólica/epidemiologia , Hepatopatia Gordurosa não Alcoólica/metabolismo , Obesidade/epidemiologia , Obesidade/metabolismo , Resultado do Tratamento , Redução de Peso
3.
Am J Gastroenterol ; 112(2): 297-302, 2017 02.
Artigo em Inglês | MEDLINE | ID: mdl-27349340

RESUMO

OBJECTIVES: Previous studies have identified an increasing number of gastroenterology (GI) procedures using anesthesia services to provide sedation, with a majority of these services delivered to low-risk patients. The aim of this study was to update these trends with the most recent years of data. METHODS: We used Medicare and commercial claims data from 2010 to 2013 to identify GI procedures and anesthesia services based on CPT codes, which were linked together using patient identifiers and dates of service. We defined low-risk patients as those who were classified as ASA (American Society of Anesthesiologists) physical status class I or II. For those patients without an ASA class listed on the claim, we used a prediction algorithm to impute an ASA physical status. RESULTS: Over 6.6 million patients in our sample had a GI procedure between 2010 and 2013. GI procedures involving anesthesia service accounted for 33.7% in 2010 and 47.6% in 2013 in Medicare patients, and 38.3% in 2010 and 53.0% in 2013 in commercially insured patients. Overall, as more patients used anesthesia services, total anesthesia service use in low-risk patients increased 14%, from 27,191 to 33,181 per million Medicare enrollees. Similarly, we observed a nearly identical uptick in commercially insured patients from 15,871 to 22,247 per million, an increase of almost 15%. During 2010-2013, spending associated with anesthesia services in low-risk patients increased from US$3.14 million to US$3.45 million per million Medicare enrollees and from US$7.69 million to US$10.66 million per million commercially insured patients. CONCLUSIONS: During 2010 to 2013, anesthesia service use in GI procedures continued to increase and the proportion of these services rendered for low-risk patients remained high.


Assuntos
Procedimentos Cirúrgicos Ambulatórios/métodos , Anestesistas/estatística & dados numéricos , Endoscopia do Sistema Digestório/métodos , Gastroenterologia/métodos , Gastos em Saúde , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Procedimentos Cirúrgicos Ambulatórios/economia , Procedimentos Cirúrgicos Ambulatórios/tendências , Anestesistas/economia , Anestesistas/tendências , Sedação Consciente/economia , Sedação Consciente/métodos , Sedação Consciente/tendências , Sedação Profunda/economia , Sedação Profunda/métodos , Sedação Profunda/tendências , Endoscopia do Sistema Digestório/economia , Endoscopia do Sistema Digestório/tendências , Feminino , Gastroenterologia/economia , Gastroenterologia/tendências , Humanos , Armazenamento e Recuperação da Informação , Modelos Logísticos , Masculino , Medicare , Pessoa de Meia-Idade , Análise Multivariada , Estados Unidos , Adulto Jovem
4.
Cancer Sci ; 108(1): 101-107, 2017 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-27727490

RESUMO

In 2016, the Japanese government decided to introduce endoscopic screening for gastric cancer as a national program. To provide endoscopic screening nationwide, we estimated the proportion of increase in the number of endoscopic examinations with the introduction of endoscopic screening, based on a national survey. The total number of endoscopic examinations has increased, particularly in clinics. Based on the national survey, the total number of participants in gastric cancer screening was 3 784 967. If 30% of the participants are switched from radiographic screening to endoscopic screening, approximately 1 million additional endoscopic examinations are needed. In Japan, the participation rates in gastric cancer screening and the number of hospitals and clinics offering upper gastrointestinal endoscopy vary among the 47 prefectures. If the participation rates are high and the numbers of hospitals and clinics are small, the proportion of increase becomes larger. Based on the same assumption, 50% of big cities can provide endoscopic screening with a 5% increase in the total number of endoscopic examinations. However, 16.7% of the medical districts are available for endoscopic screening within a 5% increase in the total number of endoscopic examinations. Despite the Japanese government's decision to introduce endoscopic screening for gastric cancer nationwide, its immediate introduction remains difficult because of insufficient medical resources in rural areas. This implies that endoscopic screening will be initially introduced to big cities. To promote endoscopic screening for gastric cancer nationwide, the disparity of medical resources must first be resolved.


Assuntos
Detecção Precoce de Câncer/métodos , Detecção Precoce de Câncer/estatística & dados numéricos , Endoscopia do Sistema Digestório/estatística & dados numéricos , Recursos em Saúde/estatística & dados numéricos , Disparidades em Assistência à Saúde/estatística & dados numéricos , Programas de Rastreamento/métodos , Programas de Rastreamento/estatística & dados numéricos , Neoplasias Gástricas/diagnóstico , Idoso , Idoso de 80 Anos ou mais , Cidades , Detecção Precoce de Câncer/instrumentação , Detecção Precoce de Câncer/tendências , Endoscopia do Sistema Digestório/tendências , Recursos em Saúde/tendências , Disparidades em Assistência à Saúde/tendências , Humanos , Japão , Programas de Rastreamento/instrumentação , Programas de Rastreamento/tendências , Pessoa de Meia-Idade , Programas Nacionais de Saúde , Saúde da População Rural
5.
Chirurg ; 81(12): 1097-107, 2010 Dec.
Artigo em Alemão | MEDLINE | ID: mdl-20706700

RESUMO

BACKGROUND: To date laparoscopic hepatic surgery is only common in a few centres for a specific selected patient group. The intention of this survey was to estimate the current state of affairs for laparoscopic hepatic surgery in Germany at 2008. MATERIALS AND METHODS: A questionnaire was prepared and sent out by e-mail in May 2009 to the members of the DGAV (German Society of General and Visceral Surgery). The feedback was evaluated anonymously. RESULTS: A total of 181 answers were received by 31st July 2009 (return rate of 15.9%). The return rate of basic and standard care hospitals was 9.2%, specialized hospitals 23.6%, hospitals with maximum care 50% and university hospitals had a return rate of 71.9%. The question whether laparoscopic hepatic surgery had been performed in 2008 was answered with YES by 125 (69.1%) and NO by 54 (29.8%) members. The number of laparoscopic hepatic surgery interventions (laparoscopic ultrasound, laparoscopic radiofrequency ablation and resection) in 2008 was given as more than 50 by 4 (2.2%) hospitals, between 20 and 50 by 11 (6.1%) hospitals, between 10 and 20 by 23 (12.7%) hospitals, between 5 and 10 by 45 (24.9%) hospitals and between 0 and 5 by 54 (29.8%) hospitals. In 2008 the frequency of laparoscopic ultrasound during intraoperative staging to confirm the diagnosis ranged from 2 to 250, whereby 96.4% of the hospitals had less than 50 and only 2 hospitals (2.7%) had 211 and 250 examinations, respectively. 50 hospitals carried out laparoscopic radiofrequency ablation (RFA). 69 (38.1%) of the interviewed hospitals reported hepatic laparoscopic resections (n=551). CONCLUSION: Laparoscopic liver surgery has been done in Germany in patients with benign or malignant liver lesions. Pure laparoscopy is the most common access. Atypical resections are the primarily indication followed by left lateral resections. All further types of resection have been done in a very small number. Laparoscopic liver surgery has been performed in all types of hospitals.


Assuntos
Comportamento Cooperativo , Endoscopia do Sistema Digestório/tendências , Gastroenterologia/tendências , Comunicação Interdisciplinar , Laparoscopia/tendências , Equipe de Assistência ao Paciente/tendências , Especialidades Cirúrgicas/tendências , Coleta de Dados , Difusão de Inovações , Previsões , Alemanha , Necessidades e Demandas de Serviços de Saúde/tendências , Humanos , Especialização/tendências , Centro Cirúrgico Hospitalar/estatística & dados numéricos , Centro Cirúrgico Hospitalar/tendências , Inquéritos e Questionários , Ultrassonografia de Intervenção/tendências
7.
Surg Endosc ; 22(3): 600-4, 2008 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-17973169

RESUMO

Natural orifice transluminal endoscopic surgery (NOTES) is a largely theoretical but potentially exciting evolution of minimally invasive surgical care. Using technology borrowed from current diagnostic and therapeutic flexible endoscopy, the idea is to replicate current laparoscopic procedures in an "incisionless" manner. It is widely recognized that for NOTES to become a practical reality, many issues need to be resolved, both methodologic and political. One critical element of development will be the design of appropriate instrumentation for NOTES. This is currently happening and involves a complex collaboration between industry and clinicians both to adapt current equipment and to design and create new tools to enable the performance of transluminal procedures. This article describes the current process of such technology development as well as the resulting instrumentation that enables the performance of NOTES. The issues of access and platform stability, laparoscopic-like instruments, and secure tissue approximation are described, and the devices to solve these issues are detailed.


Assuntos
Endoscopia do Sistema Digestório/instrumentação , Tecnologia de Fibra Óptica/instrumentação , Gastroscópios , Gastroscopia/métodos , Procedimentos Cirúrgicos Minimamente Invasivos/instrumentação , Endoscopia do Sistema Digestório/tendências , Endoscopia Gastrointestinal/métodos , Desenho de Equipamento , Segurança de Equipamentos , Feminino , Previsões , Humanos , Masculino , Sensibilidade e Especificidade , Instrumentos Cirúrgicos , Avaliação da Tecnologia Biomédica
8.
Rev. Hosp. Clin. Univ. Chile ; 17(2): 171-176, 2006.
Artigo em Espanhol | LILACS | ID: lil-532926

RESUMO

Se describen algunos hitos del desarrollo tecnológico de la endoscopia digestiva. Estos métodos fueron observados por el autor en la práctica cotidiana en el FALK Symposium, Berlín, Alemania. El diagnóstico de las lesiones es mas preciso con la imagen de la banda estrecha Narrow Band Imaging, llegando a la biopsia virtual, imagen histológica con Confocal Lase Microscopy, que forma parte de otro endoscopio. La extensión hacia la profundidad se determina con endosonografía, que a su vez esta más y más equipada para realizar cirugía endoscopica. Los limites de la cirugía endoscopica están más y más lejos, las mucosectomias más y más extensas. Además, apareció la posibilidad de la extensión de la musectomía hacia capas mas profundas, hacia la submuscosa. Se discute también la brecha tecnológica creciente, comparando nuestro hospital con los líderes mundiales.


The author describes some new milestones in technological progress of digestive endoscopy, observed in the everyday practice thanks to the FALK Symposium (Berlin, May 2006). The endoscopic diagnosis of small lesions is easier with the method of narrow band imaging (NBI), while the endoscope equipped with confocal laser microscopy provides a virtual biopsy, a histological image. The invasion of the lesions to more profound layers is determined by endosography, which is more and more adapted to perform endoscopic surgery. The feasibility and applicability of endoscopic surgery is always wider. The extension of mucosectomies is growing. In addition, there is a technical possibility to extend the mucosectomy to more profound layers, to the submucosa. The author discusses the growing distance between the level of endoscopic technology in our Hospital and in the leading hospitals of the world.


Assuntos
Humanos , Masculino , Feminino , Endoscopia do Sistema Digestório/métodos , Endoscopia do Sistema Digestório/tendências , Endoscopia do Sistema Digestório , Chile
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