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1.
J Surg Res ; 264: 454-461, 2021 08.
Artigo em Inglês | MEDLINE | ID: mdl-33848845

RESUMO

BACKGROUND: Blunt chest trauma is associated with significant morbidity, but the long-term functional status for these patients is less well-known. Return to work (RTW) is a benchmark for functional recovery in trauma patients, but minimal data exist regarding RTW following blunt chest trauma. MATERIALS AND METHODS: Patients ≥ 18 y old admitted to a Level 1 trauma center following blunt chest trauma with ≥ 3 rib fractures and length of stay (LOS) ≥ 3 d were included. An electronic survey assessing RTW was administered to patients after discharge. Patients were stratified as having delayed RTW (> 3 mo after discharge) or self-reported worse activities-of-daily-living (ADL) function after injury. Patient demographics, outcomes, and injury characteristics were compared between groups. RESULTS: Median time to RTW was 3 mo (IQR 2,5). Patients with delayed RTW had higher odds of having more rib fractures than those with RTW ≤ 3 mo (median 10 versus 7; OR:1.24, 95%CI:1.04,1.48) as well as a longer LOS (median 13 versus 7 d; OR:1.15, 95% CI:1.04,1.30). Patients with stable ADL after trauma returned to work earlier than those reporting worse ADL (median 2 versus 3.5 mo, P < 0.01). 23.6% of respondents took longer than 5 mo to return to independent functioning, and 50% of respondents' report limitations in daily activities due to physical health after discharge. CONCLUSIONS: The significant proportion of patients with poor physical health and functional status suggests ongoing burden of injury after discharge. Patients with longer LOS and greater number of rib fractures may be at highest risk for delayed RTW after injury.


Assuntos
Alta do Paciente/estatística & dados numéricos , Recuperação de Função Fisiológica , Retorno ao Trabalho/estatística & dados numéricos , Fraturas das Costelas/complicações , Ferimentos não Penetrantes/complicações , Atividades Cotidianas , Idoso , Efeitos Psicossociais da Doença , Feminino , Humanos , Escala de Gravidade do Ferimento , Tempo de Internação/estatística & dados numéricos , Masculino , Pessoa de Meia-Idade , Qualidade de Vida , Estudos Retrospectivos , Fraturas das Costelas/diagnóstico , Fraturas das Costelas/fisiopatologia , Fraturas das Costelas/terapia , Fatores de Tempo , Centros de Traumatologia/estatística & dados numéricos , Ferimentos não Penetrantes/diagnóstico , Ferimentos não Penetrantes/fisiopatologia , Ferimentos não Penetrantes/terapia
2.
Am J Emerg Med ; 37(1): 12-18, 2019 01.
Artigo em Inglês | MEDLINE | ID: mdl-29728285

RESUMO

BACKGROUND: Frailty is linked to poor outcomes in older patients. We prospectively compared the utility of the picture-based Clinical Frailty Scale (CFS9), clinical assessments, and ultrasound muscle measurements against the reference FRAIL scale in older adult trauma patients in the emergency department (ED). METHODS: We recruited a convenience sample of adults 65 yrs. or older with blunt trauma and injury severity scores <9. We queried subjects (or surrogates) on the FRAIL scale, and compared this to: physician-based and subject/surrogate-based CFS9; mid-upper arm circumference (MUAC) and grip strength; and ultrasound (US) measures of muscle thickness (limbs and abdominal wall). We derived optimal diagnostic thresholds and calculated performance metrics for each comparison using sensitivity, specificity, predictive values, and area under receiver operating characteristic curves (AUROC). RESULTS: Fifteen of 65 patients were frail by FRAIL scale (23%). CFS9 performed well when assessed by subject/surrogate (AUROC 0.91 [95% CI 0.84-0.98] or physician (AUROC 0.77 [95% CI 0.63-0.91]. Optimal thresholds for both physician and subject/surrogate were CFS9 of 4 or greater. If both physician and subject/surrogate provided scores <4, sensitivity and negative predictive value were 90.0% (54.1-99.5%) and 95.0% (73.1-99.7%). Grip strength and MUAC were not predictors. US measures that combined biceps and quadriceps thickness showed an AUROC of 0.75 compared to the reference standard. CONCLUSION: The ED needs rapid, validated tools to screen for frailty. The CFS9 has excellent negative predictive value in ruling out frailty. Ultrasound of combined biceps and quadriceps has modest concordance as an alternative in trauma patients who cannot provide a history.


Assuntos
Serviço Hospitalar de Emergência , Fragilidade/diagnóstico , Avaliação Geriátrica/métodos , Atrofia Muscular/diagnóstico por imagem , Sistemas Automatizados de Assistência Junto ao Leito , Ultrassonografia , Ferimentos não Penetrantes/fisiopatologia , Idoso , Área Sob a Curva , Feminino , Fragilidade/mortalidade , Fragilidade/fisiopatologia , Indicadores Básicos de Saúde , Humanos , Escala de Gravidade do Ferimento , Masculino , Atrofia Muscular/fisiopatologia , Valor Preditivo dos Testes , Estudos Prospectivos
3.
Anaesth Crit Care Pain Med ; 37(1): 67-71, 2018 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-28109938

RESUMO

OBJECTIVE: The aim of this study was to assess the performance of Forced Vital Capacity (FVC) for prediction of secondary respiratory complications in blunt chest trauma patients. METHODS: During a 15-month period, all consecutive blunt chest trauma patients admitted in our emergency intensive care unit with more than 3 rib fractures were eligible, unless they required mechanical ventilation in the prehospital or emergency settings. FVC was measured at admission and at emergency discharge after therapeutic interventions. The main outcome was the occurrence of secondary respiratory complications defined by hospital-acquired pulmonary infection, secondary admission in the intensive care unit or mechanical ventilation for respiratory failure or death. The performance of FVC for prediction of secondary respiratory complications was assessed by receiver operating characteristic (ROC) curve and multivariate analysis after logistic regression. RESULTS: Sixty-two consecutive patients were included and 13 (21%) presented secondary respiratory complications. Only FVC measured at emergency discharge - not FCV at admission - was significantly lower in patients who developed secondary respiratory complications (44±15 vs. 61±20%, P=0.002). The area under the ROC curves for FCV in predicting secondary pulmonary complications was 0.79 [95% CI: 0.66-0.88], P=0.0001. An FVC at discharge≤50% was independently associated with the occurrence of secondary complications with an OR at 7.9 [1.9-42.1], P=0.004. CONCLUSION: The non-improvement of FVC≤50% at emergency discharge is associated with secondary respiratory complications and should prevent the under-triage of patients with no sign of respiratory failure at admission.


Assuntos
Transtornos Respiratórios/diagnóstico , Transtornos Respiratórios/etiologia , Medição de Risco/métodos , Traumatismos Torácicos/diagnóstico , Capacidade Vital , Ferimentos não Penetrantes/diagnóstico , Idoso , Cuidados Críticos , Infecção Hospitalar/epidemiologia , Serviços Médicos de Emergência , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Admissão do Paciente , Alta do Paciente , Valor Preditivo dos Testes , Curva ROC , Transtornos Respiratórios/fisiopatologia , Respiração Artificial/estatística & dados numéricos , Insuficiência Respiratória/epidemiologia , Insuficiência Respiratória/terapia , Traumatismos Torácicos/complicações , Traumatismos Torácicos/fisiopatologia , Resultado do Tratamento , Triagem , Ferimentos não Penetrantes/complicações , Ferimentos não Penetrantes/fisiopatologia
4.
Injury ; 47(5): 1035-41, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-26944178

RESUMO

OBJECTIVES: We determine the diagnostic performance of emergent orbital computed tomography (CT) scans for assessing globe rupture in patients with blunt facial trauma. METHODS: We performed a retrospective cohort study based on prospectively collected trauma registry and acute care surveillance data in a tertiary-care hospital. Patients aged at least 18 years who underwent isolated orbital CT scanning for assessing potential ocular trauma were examined. Analyses were performed to evaluate the magnitude of agreement between diagnosis by CT scanning and ophthalmic assessment, including globe rupture. RESULTS: Our study cohort comprised 136 patients, 30% of whom (41 patients) sustained orbital wall fractures. Concordance for orbital CT diagnosis and the ophthalmic assessment of globe rupture was substantial (k=0.708). The relative risk of globe rupture was 0.692 (95% confidence interval (CI): 0.054-8.849) for superior wall fractures, 0.459 (95% CI: 0.152-1.389) for inferior wall fractures, 2.286 (95% CI: 1.062-4.919) for lateral wall fractures, and 0.637 (95% CI: 0.215-1.886) for medial wall fractures. According to multivariate analysis, lateral wall fractures were an independent risk factor for globe ruptures (adjusted odds ratio (OR)=12.01, P=0.011), and medial or inferior wall fracture was a protective factor (adjusted OR=0.14, P=0.012). In the stratified analysis of diagnostic performance of CT scan, specificity was highest among patients with orbital wall fractures (97.2%), followed by negative predictive volume (NPV, 97%), and accuracy (95.1%). CONCLUSION: Among patients with blunt facial trauma who underwent isolated orbital CT scanning as part of ocular trauma assessment, the diagnostic performance of CT in detecting globe rupture is more accurate in patients with orbital wall fractures. Nevertheless, isolated orbital CT alone does not have a sufficiently high diagnostic performance to be reliable to rule out all globe ruptures. Lateral orbital wall fractures in blunt facial trauma patients, in particular, should prompt thorough evaluation by an ophthalmologist.


Assuntos
Traumatismos Faciais/diagnóstico por imagem , Doenças Orbitárias/diagnóstico por imagem , Ruptura/diagnóstico por imagem , Esclera/lesões , Tomografia de Coerência Óptica , Tomografia Computadorizada por Raios X , Hemorragia Vítrea/diagnóstico por imagem , Ferimentos não Penetrantes/diagnóstico por imagem , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Traumatismos Faciais/complicações , Traumatismos Faciais/fisiopatologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doenças Orbitárias/fisiopatologia , Reprodutibilidade dos Testes , Estudos Retrospectivos , Sensibilidade e Especificidade , Hemorragia Vítrea/etiologia , Ferimentos não Penetrantes/complicações , Ferimentos não Penetrantes/fisiopatologia , Adulto Jovem
5.
Chin J Traumatol ; 18(4): 223-8, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26764544

RESUMO

PURPOSE: To evaluate the usefulness and information collecting ability of speckle tracking imaging techniques in the assessment of myocardial regional ventricular contractility in a rabbit model with blunt cardiac injury. METHODS: Fifteen healthy New Zealand rabbits weighing (2.70 ±0.28) kg were anesthetized (3% pentobarbital sodium/i.v) and impacted using the BIM-II biological impact machine to induce myocardial contusion (MC). Hemodynamic parameters, such as heart rate, systolic pressure, mean arterial pressure, diastolic pressure and central venous pressure, were determined before and after MC. Further, parameters reflecting left ventricular functions, such as left ventricular end systolic pressure, left ventricular end diastolic pressure, isovolumic pressure (IP) and the maximal increasing/decreasing rate of left intraventricular pressure (±dp/dtmax), were also determined before and after MC. Left ventricular functions were determined either by two dimensional transthoracic echocardiography or by speckle tracking imaging for segmental abnormal ventricular wall motions. RESULTS: Heart rate, systolic pressure, diastolic pressure and mean arterial pressure decreased significantly but transiently, while central venous pressure markedly increased after MC. In contrast to significant changes in diastolic functions, there was no significant change in cardiac systolic functions after MC. The speckle tracking imaging demonstrated that strain values of different myocardial segment significantly decreased post impact, and that of the ventricular segment decreased from segment to segment. CONCLUSION: Speckle tracking imaging is useful and informative to assess myocardial regional dysfunctions post MC.


Assuntos
Ecocardiografia , Traumatismos Cardíacos/fisiopatologia , Função Ventricular , Ferimentos não Penetrantes/fisiopatologia , Animais , Feminino , Traumatismos Cardíacos/diagnóstico por imagem , Hemodinâmica , Masculino , Contração Miocárdica , Coelhos , Ferimentos não Penetrantes/diagnóstico por imagem
6.
J Trauma Acute Care Surg ; 77(3): 427-32, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-25159246

RESUMO

BACKGROUND: The aim of this study was to evaluate the variability of clinician-performed Focused Assessment with Sonography for Trauma (FAST) examinations and its impact on abdominal computed tomography (AbCT) use in hemodynamically stable children with blunt torso trauma (BTT). The FAST is used with variable frequency in children with BTT. METHODS: We performed a planned secondary analysis of children (<18 years) with BTT. Patients with a Glasgow Coma Scale (GCS) score of less than 9, those with hypotension, and those taken directly to the operating suite were excluded. Clinicians documented their suspicion for intra-abdominal injury (IAI) as very low, less than 1%; low, 1% to 5%; moderate, 6% to 10%; high, 11% to 50%; or very high, greater than 50%. We determined the relative risk (RR) for AbCT use based on undergoing a FAST examination in each of these clinical suspicion strata. RESULTS: Of 6,468 (median age, 11.8 years; interquartile range, 6.3-15.5 years) children who met eligibility, 887 (13.7%) underwent FAST examination before CT scan. A total of 3,015 (46.6%) underwent AbCT scanning, and 373 (5.8%) were diagnosed with IAI. Use of the FAST increased as clinician suspicion for IAI increased, 11.0% with less than 1% suspicion for IAI, 13.5% with 1% to 5% suspicion, 20.5% with 6% to 10% suspicion, 23.2% with 11% to 50% suspicion, and 30.7% with greater than 50% suspicion. The patients in whom the clinicians had a suspicion of IAI of 1% to 5% or 6% to 10% were significantly less likely to undergo a CT scan if a FAST examination was performed: RR, 0.83 (0.67-1.03); RR, 0.81 (0.72-0.91); RR, 0.85 (0.78-0.94); RR, 0.99 (0.94-1.05); and RR, 0.97 (0.91-1.05) for patients with clinician suspicion of IAI of less than 1%, 1% to 5%, 6% to 10%, 11% to 50%, and greater than 50%, respectively. CONCLUSION: The FAST examination is used in a relatively small percentage of children with BTT. Use increases as clinician suspicion for IAI increases. Patients with a low or moderate clinician suspicion of IAI are less likely to undergo AbCT if they receive a FAST examination. A randomized controlled trial is required to more precisely determine the benefits and drawbacks of the FAST examination in the evaluation of children with BTT. LEVEL OF EVIDENCE: Prognostic and epidemiologic study, II.


Assuntos
Traumatismos Abdominais/diagnóstico por imagem , Traumatismos Torácicos/diagnóstico por imagem , Ferimentos não Penetrantes/diagnóstico por imagem , Traumatismos Abdominais/fisiopatologia , Adolescente , Criança , Feminino , Hemodinâmica , Humanos , Masculino , Padrões de Prática Médica/estatística & dados numéricos , Estudos Prospectivos , Risco , Traumatismos Torácicos/fisiopatologia , Tomografia Computadorizada por Raios X/estatística & dados numéricos , Ultrassonografia , Ferimentos não Penetrantes/fisiopatologia
8.
Injury ; 43(11): 1908-16, 2012 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-22884760

RESUMO

INTRODUCTION: The costs associated with patients discharged with isolated clinician-elicited persistent midline tenderness and negative computed tomography (CT) findings have not been reported. Our aim was to determine the association of acute and post-acute patient and injury characteristics with health resource costs in such patients following road trauma. METHODS: In a prospective cohort study, road trauma patients presenting with isolated persistent midline cervical tenderness and negative CT, who underwent additional acute imaging with MRI, were recruited. Patients were reviewed in the outpatient spine clinic following discharge, and were followed up at 6 and 12 months post-trauma. Multivariate linear regression was used to assess the association of injury mechanism, clinical assessment, socioeconomic factors and outcome findings with health resource costs generated in the acute hospital and post-acute periods. RESULTS: There were 64 patients recruited, of whom 24 (38%) had cervical spine injury detected on MRI. Of these, 2 patients were managed operatively, 6 were treated in cervical collars and 16 had the cervical spine cleared and were discharged. At 12 months, there were 25 patients (44%) with residual neck pain, and 22 (39%) with neck-related disability. The mean total cost was AUD $10,153 (SD=10,791) and the median was $4015 (IQR: 3044-6709). Transient neurologic deficit, which fully resolved early in the emergency department, was independently associated with higher marginal mean acute costs (represented in the analysis by the ß coefficient) by $3521 (95% CI: 50-6880). Low education standard (ß coefficient: $5988, 95% CI: 822-13,317), neck pain at 6 months (ß coefficient: $4017, 95% CI: 426-9254) and history of transient neurologic deficit (ß coefficient: $8471, 95% CI: 1766-18,334) were associated with increased post-acute costs. CONCLUSION: In a homogeneous group of road trauma patients with non fracture-related persistent midline cervical tenderness, health resource costs varied considerably. As long term morbidity is common in this population, a history of resolved neurologic deficit may require greater intervention to mitigate costs. Additionally, adequate communication between acute and community care providers is essential in order to expedite the recovery process through early return to normal daily activities.


Assuntos
Acidentes de Trânsito , Condução de Veículo , Vértebras Cervicais/lesões , Recursos em Saúde/economia , Lesões do Pescoço/economia , Dor/economia , Traumatismos da Coluna Vertebral/economia , Ferimentos não Penetrantes/economia , Adulto , Vértebras Cervicais/diagnóstico por imagem , Vértebras Cervicais/patologia , Pessoas com Deficiência , Feminino , Recursos em Saúde/estatística & dados numéricos , Humanos , Imobilização/métodos , Imageamento por Ressonância Magnética/economia , Masculino , Pessoa de Meia-Idade , Lesões do Pescoço/diagnóstico por imagem , Lesões do Pescoço/fisiopatologia , Dor/diagnóstico por imagem , Dor/fisiopatologia , Alta do Paciente , Prognóstico , Estudos Prospectivos , Fatores de Risco , Fatores Socioeconômicos , Traumatismos da Coluna Vertebral/diagnóstico por imagem , Traumatismos da Coluna Vertebral/fisiopatologia , Tomografia Computadorizada por Raios X/economia , Ferimentos não Penetrantes/diagnóstico por imagem , Ferimentos não Penetrantes/fisiopatologia
9.
Injury ; 43(10): 1667-71, 2012 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-22704784

RESUMO

INTRODUCTION: Epidural analgesia for blunt thoracic injury has been demonstrated to be beneficial for pulmonary function, analgesia, and subjective pain; however the optimal patient selection and timing of thoracic epidural placement have not been well studied. We hypothesised that early (<48h) epidural analgesia (EA) as compared with usual care involving oral and intravenous narcotics delivered by patient-controlled analgesia (PCA) in patients with blunt thoracic trauma (>3 ribs fractured) is associated with fewer pulmonary complications and lower resource utilisation as measured by ICU and hospital length of stay. METHODS: This is a retrospective review of all non-intubated patients suffering from blunt thoracic injury with 3 or more rib fractures requiring hospital admission for >24h over a recent 5-year period. Pulmonary complications were defined as pneumonia, empyema, hypoxia, and need for delayed intubation. Logistic regression was utilised to analyse patient and injury characteristics associated with pulmonary complications. RESULTS: 187 patients were included in the analysis; early thoracic epidural was utilised in 18% (n=34). There was no difference in age, ISS, ICU length of stay (LOS), or pulmonary complications between patients who received an epidural (EPI) compared with those who did not (NO EPI). A significantly increased incidence of pulmonary complications was noted in patients who required tube thoracostomy (p=0.017). CONCLUSION: In our experience, insertion of a thoracic epidural catheter early post-injury failed to reduce the incidence of pulmonary complications, ICU and hospital LOS. However, since pulmonary complications are more frequent in patients requiring tube thoracostomy, the cost-effectiveness of epidural analgesia in these patients warrants further investigation.


Assuntos
Analgesia Epidural , Analgesia Controlada pelo Paciente , Dor/tratamento farmacológico , Fraturas das Costelas/tratamento farmacológico , Ferimentos não Penetrantes/tratamento farmacológico , Adulto , Idoso , Analgesia Epidural/economia , Analgesia Controlada pelo Paciente/economia , Tubos Torácicos , Análise Custo-Benefício , Feminino , Humanos , Unidades de Terapia Intensiva , Tempo de Internação , Masculino , Pessoa de Meia-Idade , Seleção de Pacientes , Estudos Retrospectivos , Fraturas das Costelas/fisiopatologia , Fraturas das Costelas/reabilitação , Resultado do Tratamento , Estados Unidos , Ferimentos não Penetrantes/fisiopatologia , Ferimentos não Penetrantes/reabilitação
10.
J Urol ; 187(4): 1306-9, 2012 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-22341289

RESUMO

PURPOSE: The management of high grade blunt renal injury has evolved with time to become increasingly conservative with the ultimate objective of renal preservation. We evaluated relative renal function with dimercapto-succinic acid renal scintigraphy 6 months after major renal trauma (grade IV or V). MATERIALS AND METHODS: This prospective observational study was done between January 2004 and April 2010. All patients who presented with grade IV or V renal trauma and were treated conservatively were included in analysis. Patient and trauma characteristics, and initial management were recorded. Relative renal function was evaluated by dimercapto-succinic acid renal scintigraphy 6 months after trauma. RESULTS: A total of 88 patients were included in the study. Conservative management was possible in 79 patients (90%), including 69 and 10 with grade IV and V trauma, respectively. Dimercapto-succinic acid renal scintigraphy was done at 6 months for 22 patients (28%). Mean relative renal function for grade IV and V injuries was 39% and 11%, respectively (p=0.0041). The percent of devascularized parenchyma (p=0.0033) and the vascular subtype of grade IV injuries (p=0.0194) also correlated with decreased renal function. No complication or de novo arterial hypertension was noted. CONCLUSIONS: Conservative treatment achieves the objective of renal function preservation for grade IV lesions. Grade V and specific subtypes of grade IV injury have a poor functional outcome. Further study must be performed to determine which patients will benefit from conservative treatment vs early nephrectomy to avoid a longer hospital stay and useless procedures.


Assuntos
Rim/diagnóstico por imagem , Rim/lesões , Succímero , Ferimentos não Penetrantes/diagnóstico por imagem , Ferimentos não Penetrantes/fisiopatologia , Adolescente , Adulto , Feminino , Humanos , Escala de Gravidade do Ferimento , Rim/fisiopatologia , Masculino , Estudos Prospectivos , Cintilografia , Fatores de Tempo , Ferimentos não Penetrantes/terapia , Adulto Jovem
11.
J Trauma ; 71(5): 1179-84, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-21502878

RESUMO

BACKGROUND: Recent research explores the relationship between vital signs on arrival to the emergency department and early outcomes. This work has not included traumatic brain injury (TBI). We aimed to evaluate the relationship of the initial emergency department systolic blood pressure (EDSBP) with outcome. METHODS: By using the National Trauma Data Bank (v7), we analyzed patients older than 16 years with isolated moderate to severe blunt TBI. TBI was defined by International Classification of Diseases--9th Rev diagnosis codes and Abbreviated Injury Scale scores. We determined mortality rates while controlling for age, gender, race, payment type, and injury severity using logistic regression. Survival analysis was performed to determine 3-day survival rates. Scores and rates were plotted against EDSBP. RESULTS: A total of 7,238 patients were included in the analysis. Plots of adverse outcomes versus EDSBP demonstrated bimodal distributions. The mortality curve had one inflection point at EDSBP 120 mm Hg, indicating higher mortality when blood pressures were lower than this threshold. Another inflection began at EDSBP 140 mm Hg. The mortality rate was 21% when EDSBP was <120 mm Hg, 9% when it was between 120 mm Hg and 140 mm Hg, and 19% when EDSBP was ≥140 mm Hg. Multivariate analysis demonstrated that patients presenting with an EDSBP of <120 mm Hg and ≥140 mm Hg were 2.7 (95% confidence interval =2.13,3.48) and 1.6 (95% confidence interval =1.32,1.96) times more likely to die, respectively, than those who presented with a EDSBP of 120 mm Hg to 140 mm Hg. CONCLUSIONS: Mortality in moderate to severe TBI has a bimodal distribution. Like hypotension, hypertension at hospital admission seems to be associated with increased mortality in TBI, even after controlling for other factors.


Assuntos
Determinação da Pressão Arterial , Lesões Encefálicas/mortalidade , Lesões Encefálicas/fisiopatologia , Ferimentos não Penetrantes/mortalidade , Ferimentos não Penetrantes/fisiopatologia , Escala Resumida de Ferimentos , Adolescente , Adulto , Idoso , Distribuição de Qui-Quadrado , Serviço Hospitalar de Emergência , Feminino , Humanos , Cobertura do Seguro , Tempo de Internação/estatística & dados numéricos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Curva ROC , Respiração Artificial/estatística & dados numéricos , Análise de Sobrevida , Sístole , Estados Unidos/epidemiologia , Sinais Vitais
12.
J Trauma ; 71(1): 63-8, 2011 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-21427612

RESUMO

BACKGROUND: Measuring long-term disability and functional outcomes after major trauma is not standardized across trauma registries. An ideal measure would be responsive to change but not have significant ceiling effects. The aim of this study was to compare the responsiveness of the Glasgow Outcome Scale (GOS), GOS-Extended (GOSE), Functional Independence Measure (FIM), and modified FIM in major trauma patients, with and without significant head injuries. METHODS: Patients admitted to two adult Level I trauma centers in Victoria, Australia, who survived to discharge from hospital, were aged 15 years to 80 years with a blunt mechanism of injury, and had an estimated Injury Severity Score >15 on admission, were recruited for this prospective study. The instruments were administered at baseline (hospital discharge) and by telephone interview 6 months after injury. Measures of responsiveness, including effect sizes, were calculated. Bootstrapping techniques, and floor and ceiling effects, were used to compare the measures. RESULTS: Two hundred forty-three patients participated, of which 234 patients (96%) completed the study. The GOSE and GOS were the most responsive instruments in this major trauma population with effect sizes of 5.3 and 4.4, respectively. The GOSE had the lowest ceiling effect (17%). CONCLUSIONS: The GOSE was the instrument with greatest responsiveness and the lowest ceiling effect in a major trauma population with and without significant head injuries and is recommended for use by trauma registries for monitoring functional outcomes and benchmarking care. The results of this study do not support the use of the modified FIM for this purpose.


Assuntos
Avaliação de Resultados em Cuidados de Saúde/métodos , Recuperação de Função Fisiológica/fisiologia , Sistema de Registros , Centros de Traumatologia/estatística & dados numéricos , Ferimentos não Penetrantes/fisiopatologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Seguimentos , Mortalidade Hospitalar/tendências , Humanos , Masculino , Pessoa de Meia-Idade , Alta do Paciente , Estudos Prospectivos , Índices de Gravidade do Trauma , Vitória/epidemiologia , Ferimentos não Penetrantes/mortalidade , Ferimentos não Penetrantes/terapia , Adulto Jovem
13.
Am J Emerg Med ; 28(8): 956-9, 2010 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-20887915

RESUMO

We present the case of a 26-year-old man with significant periorbital trauma after blunt head trauma. Ultrasound techniques for evaluation of extraocular movements and pupillary light reflex are described as a proposed adjunct to physical examination and manual retraction of the eyelids.


Assuntos
Traumatismos Oculares/diagnóstico por imagem , Medições dos Movimentos Oculares , Movimentos Oculares/fisiologia , Reflexo Pupilar/fisiologia , Ferimentos não Penetrantes/diagnóstico por imagem , Adulto , Traumatismos Oculares/fisiopatologia , Humanos , Masculino , Ultrassonografia , Ferimentos não Penetrantes/fisiopatologia
14.
J Pediatr Surg ; 45(6): 1315-23, 2010 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-20620338

RESUMO

INTRODUCTION: Pediatric surgeon-directed trauma teams (STTs) provide lifesaving treatment but at a high cost. We used physiologically based criteria to improve STT utilization. METHODS: We reviewed 152 consecutive STT activations at one center, comparing standard and physiologically focused criteria and 24-hour hospital costs/charges for overtriaged patients vs level 2 (emergency department managed) blunt trauma patients matched for age, Injury Severity Score (ISS), and necessity for operation. RESULTS: Our cohort (73.0% male; 86.8% blunt; median age, 8.0 [interquartile range, 4.0-14.0] years) had 10 deaths (6.6%) and 18 (11.8%) emergent operations. Twenty-nine patients met neither standard nor physiologic criteria (group 1), 25 met standard but not physiologic criteria (overtriaged, group 2), and 98 met physiologic criteria (group 3). Group 3 had higher median ISS (19.0 [10.0-33.0] vs 10.0 [4.0-17.0] and 5.5 [5.0-16.75] for groups 1 and 2, P = .001), more intensive care unit admissions (67.2% vs 31.0% and 52.0%, P = .001), longer hospitalization (5.0 [3.0-9.25] days vs 3.0 [1.0-5.0] and 4.0 [2.0-5.0] days, P = .002), and all patients who died or required emergent operation (P < .001). Physiologic criteria maintained 100% sensitivity but improved specificity (49.2% vs 23.0%). Overtriaged patients (n = 18) had 78.2% higher charges ($4700; 95% confidence interval, 13.3%-180.1%; P = .013) and 53.4% higher costs ($800; 95% confidence interval, 1.8%-131.2%; P = .041) than level 2 patients (n = 259) after adjusting for age, ISS, and need for operation, largely because of computed tomography and emergency department charges (66% of overtriaged charges). CONCLUSIONS: Physiologic STT activation criteria would have saved 25 activations, $20,000 in costs, and $120,000 in charges annually without compromising patient safety.


Assuntos
Cirurgia Geral , Custos de Cuidados de Saúde/tendências , Hemodinâmica/fisiologia , Equipe de Assistência ao Paciente/estatística & dados numéricos , Centros de Traumatologia , Triagem/organização & administração , Ferimentos não Penetrantes/classificação , Adolescente , Criança , Pré-Escolar , Feminino , Seguimentos , Cirurgia Geral/economia , Humanos , Masculino , Equipe de Assistência ao Paciente/economia , Índices de Gravidade do Trauma , Estados Unidos , Recursos Humanos , Ferimentos não Penetrantes/fisiopatologia , Ferimentos não Penetrantes/cirurgia
15.
Ann Biomed Eng ; 38(2): 490-504, 2010 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-19806456

RESUMO

A mechanized and integrated computational scheme is introduced to determine the human brain responses in an environment where the human head is exposed to explosions from trinitrotoluene (TNT), or other high-yield explosives, in military applications. The procedure is based on a three-dimensional (3-D) non-linear finite element method (FEM) that implements a simultaneous conduction of explosive detonation, shock wave propagation, blast-head interactions, and the confronting human head. The processes of blast propagation in the air and blast interaction with the head are modeled by an Arbitrary Lagrangian-Eulerian (ALE) multi-material FEM formulation, together with a penalty-based fluid/structure interaction (FSI) algorithm. Such a model has already been successfully validated against experimental data regarding air-free blast and plate-blast interactions. The human head model is a 3-D geometrically realistic configuration that has been previously validated against the brain intracranial pressure (ICP), as well as shear and principal strains under different impact loadings of cadaveric experimental tests of Hardy et al. [Hardy W. N., C. Foster, M. Mason, S. Chirag, J. Bishop, M. Bey, W. Anderst, and S. Tashman. A study of the response of the human cadaver head to impact. Proc. 51 ( st ) Stapp. Car Crash J. 17-80, 2007]. Different scenarios have been assumed to capture an appropriate picture of the brain response at a constant stand-off distance of nearly 80 cm from the core of the explosion, but exposed to different amounts of a highly explosive (HE) material such as TNT. The over-pressures at the vicinity of the head are in the range of about 2.4-8.7 atmosphere (atm), considering the reflected pressure from the head. The methodology provides brain ICP, maximum shear stresses and maximum principal strain within the milli-scale time frame of this highly dynamic phenomenon. While focusing on the two mechanical parameters of pressure, and also on the maximum shear stress and maximum principal strain to predict the brain injury, the research provides an assessment of the brain responses to different amounts of over-pressure. The research also demonstrates the ability to predict the ICP, as well as the stress and strain within the brain, due to such an event. The research cannot identify, however, the specific levels of ICP, stress and strain that necessarily lead to traumatic brain injury (TBI) because there is no access to experimental data regarding head-blast interactions.


Assuntos
Traumatismos por Explosões/etiologia , Traumatismos por Explosões/fisiopatologia , Lesões Encefálicas/etiologia , Lesões Encefálicas/fisiopatologia , Modelos Neurológicos , Ferimentos não Penetrantes/etiologia , Ferimentos não Penetrantes/fisiopatologia , Força Compressiva , Simulação por Computador , Módulo de Elasticidade , Humanos , Pressão Intracraniana , Pressão , Resistência à Tração
16.
Ann Biomed Eng ; 37(7): 1403-14, 2009 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-19440839

RESUMO

The purpose of this paper is to present a protocol of inverted drop-tests using a 50th percentile Hybrid III Anthropomorphic Test Device (ATD) and investigate the influence of angle and velocity at impact on neck injury risk assessment. The tests were based on existing cadaveric experimental protocols for inverted seated positions. In this study selected ATD impact orientations were also assessed in both the sagittal and coronal planes. Twenty-six tests were performed at impact velocities from 1.4 to 3.1 m s(-1). The drop tests confirmed previously described behavior of the ATD in axial loading of its head/neck/thorax complex. They also showed a significant influence of the initial impact angle on neck injury criteria currently used by researchers in rollover crashworthiness tests. At 1.4 m s(-1), the peak upper neck axial force of 4350 N was reduced by an average 1760 +/- 80 N for configurations with 30 degrees initial impact angle in any plane, compared to a reference inverted vertical configuration. The N(ij) was also significantly influenced. For a given impact velocity, an out-of-both-planes initial configuration resulted in the highest combined outputs. Based on these results, similar dynamic conditions (intrusion velocity, impact duration) may result in significantly different loadings of the Hybrid III neck.


Assuntos
Acidentes de Trânsito , Lesões do Pescoço/etiologia , Lesões do Pescoço/fisiopatologia , Estimulação Física/efeitos adversos , Estimulação Física/instrumentação , Ferimentos não Penetrantes/etiologia , Ferimentos não Penetrantes/fisiopatologia , Simulação por Computador , Desenho de Equipamento , Humanos , Modelos Biológicos , Medição de Risco/métodos , Fatores de Risco
17.
J Surg Res ; 132(2): 214-8, 2006 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-16566939

RESUMO

BACKGROUND: The SF-36 is a commonly used general measure of health-related quality of life (QoL). The SF-12 is a related tool with less response burden, but its performance in a general trauma population is unknown. HYPOTHESIS: The SF-12 would provide similar QoL information to the SF-36 in blunt trauma patients. METHODS: Adults with nonneurological blunt injury were prospectively enrolled. Demographic, injury, and socioeconomic data were collected. Patients were assessed with functional and psychologic questionnaires 1 and 6 months after injury. Physical (PCS) and mental (MCS) component scores of the SF-36 and SF-12 were compared using Pearson's correlation coefficient. Linear regression identified factors associated with the SF-12 and SF-36 PCS and MCS. Responsiveness to change was assessed using the standardized response mean. RESULTS: Correlation of the PCS was 0.924 and MCS was 0.925 (both P < 0.001). QoL remained below population norms at 6 months. PCS was moderately responsive to change and was equivalent using either the SF-12 or the SF-36. MCS was not responsive to change using either tool. At both time points, at least 25% of patients with normal SF-12 PCS or MCS had SF-36 subscale scores significantly below the normal population. CONCLUSIONS: The SF-12 can be used to assess QoL in trauma patients. The lack of responsiveness to change of the MCS suggests other methods may be necessary to fully evaluate mental QoL. Summary scores may not be sufficient to fully assess QoL in this population. Combining the SF-12 with measures to assess psychosocial variables should be further investigated.


Assuntos
Indicadores Básicos de Saúde , Qualidade de Vida , Adulto , Feminino , Humanos , Modelos Lineares , Masculino , Fatores Socioeconômicos , Inquéritos e Questionários , Ferimentos não Penetrantes/fisiopatologia , Ferimentos não Penetrantes/psicologia
18.
J Trauma ; 58(3): 468-73; discussion 473-4, 2005 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-15761338

RESUMO

BACKGROUND: Injury is the leading cause of preventable morbidity and functional limitation in children. Long-term sequelae are measured best by the degree of impairment after recovery from the acute traumatic event. The specific aim of this study was to determine the quality of life and functional status of moderately to severely injured pediatric trauma patients at hospital discharge and at 1, 6, and 12 months postinjury. METHODS: We conducted a prospective longitudinal study of children aged 1 to 18 years with blunt injury and Injury Severity Score >/= 9, excluding head and spinal cord injury. Children were evaluated at hospital discharge and at 1, 6, and 12 months postinjury, using the Child Health Questionnaire (CHQ), the Functional Independence Measure, and the Impact on Family Scale. Baseline and 1- and 6-month data analyses are reported. RESULTS: One hundred sixty-two children were enrolled in the study, and 156 had completed 6-month data entry. The mean age was 9.3 +/- 5.3 years, and the mean Injury Severity Score was 14 +/- 7.4. The most common cause of injury was motor vehicular-related (43%). Fifty-eight (37%) had multisystem injuries. Femur fracture represented the most common injury (54.8%). Families experienced economic, social, and personal strain, as measured by the Impact on Family scale. There was a significant improvement in CHQ and Functional Independence Measure scores between baseline and 1 month and between 1 month and 6 months postinjury. However, at 6 months, physical scores remained lower than age-matched norms. CONCLUSION: Injury in children results in a significant burden on families. Although children demonstrate a rapid recovery of function and quality of life after blunt injury, physical function remains lower than age-matched norms at 6 months postinjury. It is unclear whether this represents a plateau in recovery or whether further improvements can be expected over longer time intervals.


Assuntos
Atividades Cotidianas , Qualidade de Vida , Recuperação de Função Fisiológica , Ferimentos não Penetrantes/reabilitação , Adaptação Psicológica , Adolescente , Atitude Frente a Saúde , Causalidade , Criança , Pré-Escolar , Efeitos Psicossociais da Doença , Família/psicologia , Feminino , Nível de Saúde , Hospitais Pediátricos , Humanos , Lactente , Escala de Gravidade do Ferimento , Masculino , Estudos Prospectivos , Psicologia da Criança , Perfil de Impacto da Doença , Estatísticas não Paramétricas , Inquéritos e Questionários , Fatores de Tempo , Resultado do Tratamento , Wisconsin , Ferimentos não Penetrantes/fisiopatologia , Ferimentos não Penetrantes/psicologia
19.
J Trauma ; 57(6): 1218-24, 2004 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-15625452

RESUMO

BACKGROUND: Less-lethal technologies are used in situations where lethal force is not warranted; however, a variety of injuries have been reported. Design and injury criteria are needed to assess the safety of these munitions. METHODS: Injury data from ballistic impacts of cadavers were analyzed to validate design and injury criteria. Logistic regression analysis determined the predictive ability of the blunt criterion (BC) for munition design and the viscous criterion (VC) for injury risk assessment. Differences in risk for men and women were determined. RESULTS: For a 50% risk of Abbreviated Injury Scale 2 or 3 thoracic injury, BC = 0.37 (chi = 17.71, p = 0.001) and VCmax = 0.8 m/s (chi = 11.28, p = 0.001). The 5th percentile female subject has a 36% lower tolerance to ballistic energy than the 50the percentile male subject. CONCLUSION: The BC can be used in the development of kinetic energy munitions and the VC for testing impact injury risk. These criteria provide much needed tools for the development and progression of less-lethal munitions.


Assuntos
Armas de Fogo , Balística Forense , Aplicação da Lei , Ferimentos não Penetrantes/prevenção & controle , Idoso , Cadáver , Desenho de Equipamento , Feminino , Humanos , Modelos Logísticos , Masculino , Medicina Militar , Medição de Risco , Fatores Sexuais , Ferimentos não Penetrantes/fisiopatologia
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