1.
Antimicrob Agents Chemother
; 51(10): 3760-2, 2007 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17682101
RESUMO
Amphotericin B and flucytosine (5FC) have an additive effect when used for disseminated candidiasis. Here, we bridge the results of an experimental pharmacodynamic study to humans and demonstrate that a 5FC dosage of 25 mg/kg of body weight/day in four divided doses in combination with amphotericin B produces near-maximal effect.