RESUMO
BACKGROUND: Industry payments to US cancer centers are poorly understood. METHODS: US National Cancer Institute (NCI)-designated comprehensive cancer centers were identified (n = 51). Industry payments to NCI-designated comprehensive cancer centers from 2014 to 2021 were obtained from Open Payments and National Institutes of Health (NIH) grant funding from NIH Research Portfolio Online Reporting Tools (RePORT). Given our focus on cancer centers, we measured the subset of industry payments related to cancer drugs specifically and the subset of NIH funding from the NCI. RESULTS: Despite a pandemic-related decline in 2020-2021, cancer-related industry payments to NCI-designated comprehensive cancer centers increased from $482 million in 2014 to $972 million in 2021. Over the same period, NCI research grant funding increased from $2â481â million to $2â724â million. The large majority of nonresearch payments were royalties and licensing payments. CONCLUSION: Industry payments to NCI-designated comprehensive cancer centers increased substantially more than NCI funding in recent years but were also more variable. These trends raise concerns regarding the influence and instability of industry payments.
Assuntos
Institutos de Câncer , Indústria Farmacêutica , National Cancer Institute (U.S.) , National Institutes of Health (U.S.) , Apoio à Pesquisa como Assunto , Estados Unidos , Humanos , National Cancer Institute (U.S.)/economia , Indústria Farmacêutica/economia , Indústria Farmacêutica/tendências , Apoio à Pesquisa como Assunto/tendências , Apoio à Pesquisa como Assunto/economia , National Institutes of Health (U.S.)/economia , Institutos de Câncer/economia , Conflito de Interesses/economia , Antineoplásicos/economia , Neoplasias/economiaRESUMO
BACKGROUND: In Ghana, breast cancer remains the most common cancer and the leading cause of cancer deaths among women. The cost of treating cancer is huge and poses a great challenge for patients, their families, and health care systems. While comprehensive studies have been conducted on the economic burden of cancers in developed economies such as the EU and the US, there are limited studies in Africa, and Ghana, in particular. This study quantitatively assessed Ghana's direct and indirect costs of breast cancer treatment. METHODS: Primary data were collected using a questionnaire administered to 217 breast cancer patients at the Korle-Bu and Komfo Anokye Teaching Hospitals, Ghana's two leading hospitals, and Sweden Ghana Medical Centre. Direct and indirect costs were computed using the Cost-of-Illness Approach. Quantitative analysis was done using multivariate linear regression. RESULTS: The findings showed that the breast cancer patients studied paid a median amount of Ghana cedis (GHC) 31,021.0 (IQR; 25,262.5-42,147.0), approximating USD 5,500.2 (IQR: 4,477.0-7,469.2 USD) for their treatment within one year of active treatment in 2019. About 61.9% (95% CI: 61.8-62.0%) of this cost was direct cost, while the remaining 38.1% (95% CI: 38.0-38.1%) was indirect cost. Patients who sought care from public facilities for breast cancer paid a median amount of GHC 29,606.3 (USD 5,249.3), while those who sought care from private facilities paid GHC 55,071.2 (USD 9,744.4). Findings from the multivariate linear regression indicate that being married/cohabiting, divorced/separated and having tertiary level education predicted higher cost of breast cancer treatment while patients on retirement and patients in the middle stage (Stage II) of breast cancer diagnoses were associated with lower cost of breast cancer treatment. CONCLUSIONS: The cost of breast cancer treatment poses a significant burden on patients and their families. There is a need for increased public funding for breast cancer treatment to reduce the huge economic burden its treatment poses for patients and their families.
Assuntos
Neoplasias da Mama , Humanos , Gana/epidemiologia , Feminino , Neoplasias da Mama/economia , Neoplasias da Mama/terapia , Pessoa de Meia-Idade , Adulto , Idoso , Efeitos Psicossociais da Doença , Custos de Cuidados de Saúde , Inquéritos e Questionários , Institutos de Câncer/economiaRESUMO
BACKGROUND: Federal rules mandate that hospitals publish payer-specific negotiated prices for all services. Little is known about variation in payer-negotiated prices for surgical oncology services or their relationship to clinical outcomes. We assessed variation in payer-negotiated prices associated with surgical care for common cancers at National Cancer Institute (NCI)-designated cancer centers and determined the effect of increasing payer-negotiated prices on the odds of morbidity and mortality. MATERIALS AND METHODS: A cross-sectional analysis of 63 NCI-designated cancer center websites was employed to assess variation in payer-negotiated prices. A retrospective cohort study of 15,013 Medicare beneficiaries undergoing surgery for colon, pancreas, or lung cancers at an NCI-designated cancer center between 2014 and 2018 was conducted to determine the relationship between payer-negotiated prices and clinical outcomes. The primary outcome was the effect of median payer-negotiated price on odds of a composite outcome of 30 days mortality and serious postoperative complications for each cancer cohort. RESULTS: Within-center prices differed by up to 48.8-fold, and between-center prices differed by up to 675-fold after accounting for geographic variation in costs of providing care. Among the 15,013 patients discharged from 20 different NCI-designated cancer centers, the effect of normalized median payer-negotiated price on the composite outcome was clinically negligible, but statistically significantly positive for colon [aOR 1.0094 (95% CI 1.0051-1.0138)], lung [aOR 1.0145 (1.0083-1.0206)], and pancreas [aOR 1.0080 (1.0040-1.0120)] cancer cohorts. CONCLUSIONS: Payer-negotiated prices are statistically significantly but not clinically meaningfully related to morbidity and mortality for the surgical treatment of common cancers. Higher payer-negotiated prices are likely due to factors other than clinical quality.
Assuntos
Institutos de Câncer , National Cancer Institute (U.S.) , Humanos , Estados Unidos , Estudos Retrospectivos , Feminino , Masculino , Institutos de Câncer/economia , Estudos Transversais , National Cancer Institute (U.S.)/economia , Idoso , Medicare/economia , Neoplasias Pancreáticas/cirurgia , Neoplasias Pancreáticas/economia , Neoplasias/cirurgia , Neoplasias/economia , Neoplasias Pulmonares/cirurgia , Neoplasias Pulmonares/economia , Seguimentos , Taxa de Sobrevida , Prognóstico , Complicações Pós-Operatórias/economia , Neoplasias do Colo/cirurgia , Neoplasias do Colo/economiaRESUMO
BACKGROUND: To evaluate the economic loss of hospital-acquired infections (HAIs) among tumor patients so as to help policymakers to allocate health care resources and address the issue. METHODS: We conducted a retrospective, 1:1 matched case-control study in a large region cancer hospital between January 1 and December 31, 2022. The economic burden was estimated as the median of the 1:1 pair differences of various hospitalization fees and hospital length of stay (LOS). RESULTS: In this study of 329 matched pairs, the patients with HAIs incurred higher hospitalization cost (ie, $16,927) and experienced longer hospital LOS (ie, 22 days), compared to the non-HAI groups. The extra hospitalization cost and the prolonged hospital LOS caused by HAIs were $4,919 and 9 days, respectively. Accordingly, the direct nonmedical economic loss attributable to HAI was approximately $478 to 835 per case. Furthermore, the increment of hospitalization costs varied by sites of infection, types of tumors, and stratum of age. CONCLUSIONS: HAIs lead to the increment of direct economic burden and hospital LOS in tumor patients. Our findings highlight the importance of implementing effective infection control measures in hospitals to reduce the financial burden on tumor patients.
Assuntos
Infecção Hospitalar , Neoplasias , Humanos , Infecção Hospitalar/economia , Infecção Hospitalar/epidemiologia , China/epidemiologia , Masculino , Feminino , Estudos Retrospectivos , Pessoa de Meia-Idade , Neoplasias/economia , Neoplasias/epidemiologia , Estudos de Casos e Controles , Idoso , Adulto , Efeitos Psicossociais da Doença , Tempo de Internação/economia , Tempo de Internação/estatística & dados numéricos , Hospitalização/economia , Hospitalização/estatística & dados numéricos , Institutos de Câncer/economia , Idoso de 80 Anos ou mais , Custos de Cuidados de Saúde/estatística & dados numéricosRESUMO
Objetivo Se realiza una aproximación a las barreras geográficas y económicas para el acceso a los servicios oncológicos del Instituto Nacional de Cancerología-INC; Se presenta la necesidad de plantear alternativas para afrontar estas problemáticas y considerar estudios que evalúen problemáticas similares y sus soluciones Métodos Se utilizaron los métodos cualitativo y cuantitativo en lo referente a datos estadísticos, dentro de un contexto de interés social, con un enfoque empírico analítico. Resultados Se encontró que durante el 2005, tuvieron acceso al programa de albergues solo 176 pacientes de los 3 391 pacientes provenientes de regiones del país distintas a Bogotá atendidos en el mismo periodo; es decir que el programa solo cubrió el 5,19 por ciento de los pacientes de diferentes lugares del país. De igual manera se encontró que se debe afrontar la inequidad de género que hasta la fecha se ha venido presentando con los varones. Conclusiones Se deben buscar alternativas de alojamiento diferentes a los albergues, que hagan posible el acceso al tratamiento especializado con dignidad y calidad de vida. El estudio permitió plantear alternativas de solución a corto, mediano y largo plazo.
Objective Geographical and economic barriers to access to National Cancer Institute (NCI) oncology services were evaluated; such approach revealed the need for alternatives for dealing with these issues and considering studies aimed at assessing similar problems and resolving them. Methods An analytical empirical approach used qualitative and quantitative statistical methods were used within a context of social concern. Results Only 176 out of 3 391 patients had access to the "Temporary-housing programme" during 2005, covering 5,19 percent of all patients coming from remote regions of Colombia. Most patients were women who were looking for alternatives outside the institutional programmes being offered. Conclusion There is a need to fix gender inequity and search for better housing alternatives to providing refuges, providing access to specialised treatment and the need for attending people with dignity and ensuring quality of life. The study led to proposing new short-, medium- and long-term alternatives for improving health service access.