Characterization and childhood exposure assessment of toxic heavy metals in household dust under true living conditions from 10 China cities.

Health hazards caused by metal exposure in household dust are concerning environmental health problems. Exposure to toxic metals in household dust imposes unclear but solid health risks, especially for children. In this multicenter cross-sectional study, a total of 250 household dust samples were collected from ten stratified cities in China (Panjin, Shijiazhuang, Qingdao, Lanzhou, Luoyang, Ningbo, Xi'an, Wuxi, Mianyang, Shenzhen) between April 2018 and March 2019. Questionnaire was conducted to gather information on individuals' living environment and health status in real-life situations. Multivariate logistic regression and principal component analysis were conducted to identify risk factors and determine the sources of metals in household dust. The median concentration of five metals in household dust from 10 cities ranged from 0.03 to 73.18 µg/g. Among the five heavy metals, only chromium in household dust of Mianyang was observed significantly both higher in the cold season and from the downwind households. Mercury, cadmium, and chromium were higher in the third-tier cities, with levels of 0.08, 0.30 and 97.28 µg/g, respectively. There were two sources with a contribution rate of 38.3 % and 25.8 %, respectively. Potential risk factors for increased metal concentration include long residence time, close to the motorway, decoration within five years, and purchase of new furniture within one year. Under both moderate and high exposure scenarios, chromium showed the highest level of exposure with 6.77 × 10-4 and 2.28 × 10-3 mg·kg-1·d-1, and arsenic imposed the highest lifetime carcinogenic risk at 1.67 × 10-4 and 3.17 × 10-4, respectively. The finding highlighted the priority to minimize childhood exposure of arsenic from household dust.

Assessment of human exposure to cadmium and its nephrotoxicity in the Chinese population.

BACKGROUND: Cadmium (Cd) is a toxic heavy metal that widely detected in environment and accumulated in kidney, posing a great threat to human health. However, there is a lack of systematic investigation of exposure profile and association of Cd exposure with renal function in the Chinese population. METHODS: Related articles were searched from PubMed, Web of Science, China National Knowledge Internet, and Wanfang to construct an aggregate exposure pathway (AEP) framework for Cd and to explore the correlation between Cd and renal function using random effects models. RESULTS: A total of 220 articles were included in this study, among which 215 investigated human exposure and 12 investigated the association of Cd with renal outcomes. The AEP framework showed that 96.5 % and 62.5 % of total Cd intake were attributed to dietary intake in nonsmokers and smokers, respectively. And 35.2 % originated from cigarette smoke inhalation in smokers. In human body, Cd was detected in blood, urine, placenta, etc. Although the concentrations of Cd in blood and urine from subjects living in polluted areas showed a sharp downward trend since the early 21st century, higher concentration of Cd in the environment and human body in polluted areas was found. Kidney was the target organ. The level of blood Cd was positively associated with urinary ß2-microglobulin [ß2-MG, r (95 % CI) = 0.12 (0.05, 0.19)], albumin [0.13 (0.06, 0.20)], and retinol-binding protein [RBP, 0.14 (0.03, 0.24)]. Elevated urinary Cd was correlated with increases in ß2-MG [0.22 (0.15, 0.29)], albumin [0.23 (0.16, 0.29)], N-acetyl-ß-d-glucosaminidase [NAG, 0.33 (0.22, 0.44)], and RBP [0.22 (0.14, 0.30)]. CONCLUSIONS: Foods and cigarette smoke were two major ways for Cd intake, and Cd induced renal injury in the Chinese population. This study enhanced the understanding of human exposure and nephrotoxicity of Cd, and emphasized the need for controlling Cd level in polluted areas.

Potentially toxic metals in irrigation water, soil, and vegetables and their health risks using Monte Carlo models.

Food safety has become a serious global concern because of the accumulation of potentially toxic metals (PTMs) in crops cultivated on contaminated agricultural soils. Amongst these toxic elements, arsenic (As), cadmium (Cd), chromium (Cr), and lead (Pb) receive worldwide attention because of their ability to cause deleterious health effects. Thus, an assessment of these toxic metals in the soils, irrigation waters, and the most widely consumed vegetables in Nigeria; Spinach (Amaranthushybridus), and Cabbage (Brassica oleracea) was evaluated using inductively coupled plasma-optical emission spectroscopy (ICP-OES). The mean concentration (measured in mg kg-1) of the PTMs in the soils was in the sequence Cr (81.77) > Pb(19.91) > As(13.23) > Cd(3.25), exceeding the WHO recommended values in all cases. This contamination was corroborated by the pollution evaluation indices. The concentrations (measured in mg l-1) of the PTMs in the irrigation water followed a similar pattern i.e. Cr(1.87) > Pb(1.65) > As(0.85) > Cd(0.20). All the PTMs being studied, were found in the vegetables with Cr (5.37 and 5.88) having the highest concentration, followed by Pb (3.57 and 4.33), and As (1.09 and 1.67), while Cd (0.48 and 1.04) had the lowest concentration (all measured in mg kg-1) for cabbage and spinach, respectively. The concentration of the toxic metals was higher in spinach than in cabbage, which may be due to the redistribution of the greater proportion of the metals above the ground tissue, caused by the bioavailability of metals in the aqueous phase. Expectedly, the hazard index (HI),and carcinogenic risk values of spinach were higher than that of cabbage. This implies that spinach poses potentially higher health risks. Similarly, the Monte Carlo simulation results reveal that the 5th percentile, 95th percentile, and 50th percentile of the cumulative probability of cancer risks due to the consumption of these vegetables exceeds the acceptable range of 1.00E-6 and 1.00E-4. Thus, the probable risk of a cancerous effect is high, and necessary remedial actions are recommended.

Exposure Assessment of Essential and Potentially Toxic Metals in Wheat-Based Sweets for Human Consumption: Multivariate Analysis and Risk Evaluation Studies.

In recent years, there has been a growing concern about the negative impact of unforeseen contaminants such as metals in commonly consumed food items, which pose a threat to human well-being. Therefore, it is of utmost importance to evaluate the levels of these contaminants to guarantee the safe consumption of these food items. The goal of the current research is to determine the levels of essential (EMs: Mg, Ca, Mn, Fe, Co, Cu, and Zn) and potentially toxic metals (PTMs: Al, Cr, Ni, As, Cd, and Pb) in various brands of wheat-based sweets. One hundred samples were collected and analysed via flame atomic absorption spectrometry (FAAS) and inductively coupled plasma-optical emission spectrometry (ICP-OES). Also, the current study was to investigate the distribution, correlation, and multivariate analysis of 13 metals (Mg, Ca, Mn, Fe, Co, Cu, Zn, Al, Cr, Ni, As, Cd, and Pb). Hierarchical cluster analysis (HCA) and principal component analysis (PCA) were used to interpret the metals' association. The concentration (mg/kg) ranges of EMs were, in order, Mg (12.70-65.67), Ca (24.02-209.12), Mn (1.32-9.61), Fe (4.55-111.23), Co (0.32-8.94), Cu (2.12-8.61), and Zn (2.60-19.36), while the concentration (mg/kg) ranges of PTMs were, in order, Al (0.32-0.87), Cr (0.17-5.74), Ni (0.36-1.54), Cd (0.16-0.56), and Pb (0.14-0.92), and As was not detected in any sample under investigation. The HCA data revealed that Co, Al, and Ni form clusters with other metals. Sweets are prepared at high temperatures, and the elevated temperatures can increase the likelihood of Ni and Al leaching from stainless steel. Tolerable dietary intake (TDI) values for Ni were higher than the values established by the European Food Safety Authority (EFSA). The CR value found for the Ni and Cr was at the threshold level of cancer risk, if an amount of 25 g were to be used over a lifetime. In a nutshell, this study highlights the monitoring of EM and PTM levels in wheat-based sweets, and from a food safety perspective, the study is important for consumers of wheat-based sweets.

The role of chemical fractionation in risk assessment of toxic metals: a review.

The identification of highly toxic metals like Cd, Ni, Pb, Cr, Co or Cu in ambient particulate matter (PM) has garnered a lot of interest recently. Exposure to toxic metals, including carcinogenic ones, at levels above recommended limits, can significantly affect human health. Prolonged exposure to even trace amounts of toxic or essential metals can also have negative health impacts. In order to assess significant risks, it is crucial to govern the concentrations of bioavailable/bio-accessible metals that are available in PM. Estimating the total metal concentrations in PM is only an approximation of metal toxicity. This review provides an overview of various procedures for extracting soluble toxic metals from PM and the importance of chemical fractionation in risk assessment. It is observed that the environmental risk indices such as bioavailability index (BI), contamination factor (CF) and risk assessment code (RAC) are specifically influenced by the concentration of these metals in a particular fraction. Additionally, there is compelling evidence that health risks assessed using total metal concentrations may be overestimated, therefore, the metal toxicity assessment is more accurate and more sensitive to the concentration of the bioavailable/bio-accessible fraction than the total metal concentrations. Hence, chemical fractionation of toxic metals can serve as an effective tool for developing environmental protection laws and improving air quality monitoring programs for public health.

Monitoring the spatial distribution pattern according to urban land use and health risk assessment on potential toxic metal contamination via street dust in Ankara, Türkiye.

The urbanization processes with growing vehicle numbers cause heavy metal pollution in street dust, and high populations in metropolitan cities are exposed to pollutants. This paper aims to monitor the spatial distribution of heavy metals and evaluate the concentrations via health risk assessment of HMs (Cu, Ni, Cd, Co, Pb, and Zn) that expose the inhabitants to health hazards. According to the results of the current study, sixty street dust samples were applied to the acid digestion technique and quantification by inductively coupled plasma-mass spectrometry (ICP-MS). The spatial distribution of the selected heavy metals in the street dust was investigated using the spatial analysis tool in ArcGIS 10.0 according to population density and land use. In the present study, we used hazard index and cancer risk methods to estimate the public health risk of the pollutants exposed to street dust in Ankara. The concentrations range of the elements in street dust over the study area ranged from 3.34-4.50, 31.69-42.87, 16.09-21.54, 42.85-57.55, 0.00-3.51, and 23.03-30.79, respectively. The overall decreasing order of mean concentration of metals was observed as follows: Pb > Cu > Ni > Co > Cd > Zn. Vehicle traffic and industrial activities seem to be the most critical anthropogenic sources responsible for dust pollution in the study area. The risk assessment of Pb and Ni exposure was the highest, and the hazard index values were 2.42E + 00 and 2.28E + 00 mg/kg/day for children. However, the effect on adults was 2.62E-01 and 2.37E-02 mg/kg/day, followed by inhalation and dermal contact with street dust was almost negligible. The decreasing concentration is modeled spatially along the western development corridor of the city. The risk to public health is high in areas with high densities close to the city center and the main artery.

Monte Carlo simulation and delayed geochemical hazard revealed the contamination and risk of arsenic in natural water sources.

Due to its ubiquity and carcinogenicity, the geochemical behavior and health risks of arsenic (As) have been a research focus worldwide. A comprehensive investigation was conducted on the contamination and ecological and health risks of As in the Zijiang River (ZR)-a natural water source. The concentration ranges of As were separately 1.36-6.23 µg/L, 11.42-74.53 mg/kg, and 1.26-130.68 µg/L in surface waters (dissolved), sediments, and pore waters. The concentrations of As in the midstream pore waters and sediments were relatively high, which was related to mining, dam interception, and sediment resuspension. The Monte Carlo simulation results showed that the occurrence probability of As contamination and static risk in sediments was low, however, in the midstream, the secondary risk caused by the release of As should be given more consideration. In the sediments, the transformation paths and the dynamic risk of As were explored based on the delayed geochemical hazard model, showing that there was a probability of a potential burst of 26.47% - 55.88% in the sediments of the ZR. Although at the detected surface waters, the total risk of the noncarcinogenicity and carcinogenicity of As were low, overall adults have lower health risks than children, and As exposure in children should be of concern. This study complements the further understanding of the geochemical behavior of arsenic, which can be extended to other toxic metal(loid)s.

Assessment of lead, cadmium, and mercury levels in the breast milk in Pakistani women.

The concentrations of potentially toxic metals like lead (Pb), cadmium (Cd), and mercury (Hg) in healthy lactating mothers of Lahore city were estimated during 2020-2021 with the help of a flame atomic absorption spectrometer (FAAS). Seventy samples of breast milk were collected from two different age groups, namely, G-1 (25-30 years) and G-2 (31-40 years). The results showed that Cd contents were below the detection limit of the measuring instrument; however, the Pb and Hg contents were detected with great ease. The mean concentrations of Pb and Hg in the G-1 corresponding to the age between 25 and 30 years were observed to be 1.914 ± 0.493 µg/L and 10.432 ± 3.249 µg/L, respectively. For the G-2 with an age limit between 31 and 40 years, the concentrations of Pb and Hg were estimated to be 2.045 ± 0.502 µg/L and 11.527 ± 3.231 µg/L, respectively. The T-test analysis of concentrations of these toxic metals indicated a significant correlation between the content levels of Pb and Hg (p < 0.05). The observed values of toxic metals were significantly more frequent than those suggested by WHO (World Health Organization). An increase in the concentrations of Pb and Hg is directly associated with the location of the target population. As a result, it is turned out that the majority of the lactating woman with significantly high levels of Pb and Hg belongs to industrial areas of Lahore. To avoid such conditions, residential areas must be at larger distances, in addition, to strictly abiding by the environmental policies of the government.

Human health risk assessment of potentially toxic elements in the breast milk consumed by infants in Western Iran.

This study aimed to assess the human health risk of some toxic metals/metalloids [lead (Pb), mercury (Hg), cadmium (Cd), nickel (Ni), chromium (Cr), and arsenic (As)] on infants via consumption of the breast milk of women living in urban areas of Kermanshah city, west of Iran. After collecting milk samples, the carcinogenic and non-carcinogenic risk assessment as well as uncertainty analysis of toxic metal levels were carried out. The order of concentration of heavy metals/metalloids in the breast milk samples was Cr (41.07 ± 23.19) > Ni (19.25 ± 11.81) > Pb (11.5 ± 4.48) > As (1.96 ± 2.04) > Cd (.72 ± 0.42) > Hg (0.31 ± 0.26). The results revealed that the levels of Cr and Pb in the breast milk samples were exceeded the World Health Organization (WHO) tolerable daily intake. In the breast milk samples a high levels of one of the trace elements As, Cd, Cr, Pb, and Ni were observed (over 73%) and in 40% of them the levels of Cr, Pb, Cd, As, and Ni were all above WHO tolerable daily intake. Moreover, the As-related point assessment of target risk factor (THQ) was higher than the allowable limit only for 1-month-old male neonates and 2-month-old female neonates (THQ > 1). In addition, Cr-related THQ scores were higher at all age and gender groups (THQ > 1). In conclusion, our findings suggest a potential risk of some metals for infants via the consumption of mothers' breast milk.

Risk assessment of combined exposure to lead, cadmium, and total mercury among the elderly in Shanghai, China.

Lead (Pb), cadmium (Cd) and total mercury (THg) are toxic heavy metals (THMs) that are widely present in the environment and can cause substantial health problems. However, previous risk assessment studies have rarely focused on the elderly population and have usually targeted a single heavy metal, which might underestimate the long-term accumulative and synergistic effects of THMs in humans. Based on the food frequency questionnaire and inductively coupled plasma mass spectrometry, this study assessed external and internal exposures to Pb, Cd and THg in 1747 elderly people in Shanghai. Probabilistic risk assessment with the relative potential factor (RPF) model was used to assess the neurotoxicity and nephrotoxicity risks of combined THMs exposures. The mean external exposures of Pb, Cd and THg in Shanghai elderly were 46.8, 27.2 and 4.9 µg/day, respectively. Plant-based foods are the main source of Pb and THg exposure, while Cd is mainly from animal-based foods. The mean concentrations of Pb, Cd and THg were 23.3, 1.1 and 2.3 µg/L in the whole blood, and 6.2, 1.0 and 2.0 µg/L in the morning urine, respectively. Combined exposure to THMs leading to 10.0 % and 7.1 % of Shanghai elderly at risk of neurotoxicity and nephrotoxicity. The results of this study have important implications for understanding the profiles of Pb, Cd and THg exposure in the elderly living in Shanghai and provide data support for risk assessment and control of nephrotoxicity and neurotoxicity from combined THMs exposure in the elderly.

Carcinogenic and human health risk assessment of children's and adults' exposure to toxic metal(oid)s from air PM10 in critical sites of the Republic of Serbia.

With global urbanization and industrialization, air pollution has become an inevitable problem. Among air pollutants, toxic metals bound to particulate matter (PM) have a high hazardous potential, contributing to the development of several diseases, including various types of cancer. Due to PM pollution, Serbia is considered to be among the most polluted countries in Europe. Therefore, the objective of the study was to assess and characterize the non-carcinogenic and carcinogenic risks of children's and adults' exposure to metal(oid)s (Pb, Cd, Ni, and As) bound to PM10 in five of the most polluted areas in the Republic of Serbia (Subotica, Smederevo, Bor, Valjevo, and Kraljevo). Non-carcinogenic (HQ and HI) and carcinogenic risk (CR) were calculated using USEPA methodology. Our results show that PM10 concentrations exceeded the annual limit of 40 µg/m3 at four out of five monitoring sites (ranging from 44.33 to 63.25 µg/m3). Results obtained from Bor monitoring station show that safe limits were exceeded for both children and adults, indicating an unacceptable risk (> 1) obtained for inhalation exposure to the As (HQ = 6.14) and Cd (HQ = 1.17), while total HI was 7.43, which characterized the risk as unacceptable. For the same station, the CR value was 1.44E-04 (> 1 × 10-4). In other sites, the risks were acceptable. The characterized risk from exposure to the toxic elements via PM10 in critical locations in Serbia contributes to improving air quality by requiring regulatory organs to take new actions and adopt new measures to reduce air pollution.

Evaluation of potential toxic heavy metal contamination in soil, fly ash, vegetables and grain crops along with associated ecological and health risk assessment of nearby inhabitants of a thermal power station in Jharkhand (India).

The present study aimed to evaluate the potential toxic heavy metal (PTHM) concentrations and associated ecological and health risk of nearby inhabitants (child and adult populations) of the Bokaro thermal power station (BTPS), Jharkhand, India. The fly ash containing PTHMs is released from the thermal power plant and contaminates the soil of the nearby agricultural area, roadside area and residential area. Furthermore, PTHMs cause ecological risk as well as carcinogenic health effects in adults. Inhabitants are exposed to PTHMs through exposure pathways (for instance, direct ingestion, dermal contact and air inhalation), and PTHMs were examined in this study by calculating the estimated daily intake (EDI). The contamination factor (Cf) of Cd exceeded the threshold value throughout the study area, whereas the Cf of Hg was observed higher only in roadside soil (RSS). The geoaccumulation index (Igeo) of Cd was higher in the top soil of agricultural soil (AS) (7.39) and RSS (9.38). The level of PTHMs was monitored slightly higher in the topsoil of RSS. The ecological risk index (Eri) was detected to be the highest in RSS (1628.9). The permissible limit of Cd (0.05 mg kg-1) and Pb (0.1 mg kg-1) for all sampled vegetables and grain crops was surpassed. The transfer factor (TF) of the studied vegetables and grain crops was in the order of Cd > Cr > Pb > Hg > As. The results of the present study concluded that the hazard quotient (HQ) values for all PTHMs analysed in soil throughout the study area were < 1, which indicates that the child population was within the safe limit. However, the adult population was at a high risk of non-carcinogenic health effects due to increased permissible limits of Cd, Pb and Cr in vegetables and grain crops whereas the target carcinogenic risk (TCR) of Pb and Cr was higher and indicated that there may be a health risk of cancer in adults.

Investigation of health risk assessment and the effect of various irrigation water on the accumulation of toxic metals in the most widely consumed vegetables in Iran.

The quality of irrigation water sources can significantly affect the concentrations of heavy metals (HMs) in cultivated vegetables. This study aimed to investigate the effect of various water resources, including treated wastewater effluent (TWE), river water (RW), and well water with chemical fertilizer (WW+F), on the accumulation of heavy metals (HMs) in the three most widely consumed edible vegetables (Coriander, Radish, and Basil) in Iran. A total of 90 samples of edible vegetables, 13 samples of irrigation water, and 10 soil samples were collected to determine HMs concentrations. Iron (Fe), Zinc (Zn), Copper (Cu), Manganese (Mn), Lead (Pb), Cadmium (Cd), Chromium (Cr), Nickel (Ni,) and Arsenic (As) were analyzed by inductively coupled plasma optical emission spectrometry (ICP-OES). Eventually, the Total Target Hazard Quotient (TTHQ) for the toxic metals of As, Pb, and Cd was determined. The results revealed that the TTHQ of toxic metals in vegetables was less than the allowable limits (TTHQ = 1). Also, TWE was the best irrigation water type since the HMs content of vegetables was low. By comparing the results with national and international standards, it can be concluded that the Gharasou RW for irrigation of edible vegetables was inappropriate.

Exposure to Toxic Metals and Health Risk Assessment through Ingestion of Canned Sardines Sold in Brazil.

The presence of heavy metals in the environment is increasing, which can be a danger to public health. Fish exposed to contaminated environments tend to have higher concentrations of some metals in their tissues. Monitoring these elements remains urgent as it is a matter of global concern. Canned sardines from the Brazilian market were analyzed for elements (Al, As, Ba, Cd, Co, Cr, Cu, Fe, Ni, Pb, Se, and Zn) of metals and metalloids, including some toxic, using inductively coupled plasma optical spectrometry (ICP OES) in two types of sardines (preserved in oil and tomato sauce) from five different brands. The results were compared to limit levels for consumption set by FAO/WHO. Moreover, we assessed the associated risk regarding the elemental intake of these elements through the samples, using the hazard quotient (HQ), hazard index (HI), and carcinogenic risk (CR). All samples had unfavorable HQ and HI, primarily due to arsenic content. In the same manner, CR for arsenic was above the proposed limit of 10-4, and cadmium and chromium, which were within the acceptable limit (10-6 to 10-4), require attention. These results show that chronic consumption of canned sardines sold in Brazil is unsafe, and quality surveillance is needed to ensure there is no risk to the population that ingests these products.

Removal of toxic heavy metals using genetically engineered microbes: Molecular tools, risk assessment and management strategies.

The direct release of industrial effluent into the water and other anthropogenic activities causes water pollution. Heavy metal ions are the primary contaminant in the industrial effluents which are exceptionally toxic at low concentrations, terribly disturb the endurance equilibrium of activities in the eco-system and be remarkably hazardous to human health. Different conventional treatment methodologies were utilized for the removal of toxic pollutants from the contaminated water which has several drawbacks such as cost-ineffective and lower efficiency. Recently, genetically modified micro-organisms (GMMs) stand-out for the removal of toxic heavy metals are viewed as an economically plausible and environmentally safe technique. GMMs are microorganisms whose genetic material has been changed utilizing genetic engineering techniques that exhibit enhanced removal efficiency in comparison with the other treatment methodologies. The present review comments the GMMs such as bacteria, algae and fungi and their potential for the removal of toxic heavy metals. This review provides current aspects of different advanced molecular tools which have been used to manipulate micro-organisms through genetic expression for the breakdown of metal compounds in polluted areas. The strategies, major limitations and challenges for genetic engineering of micro-organisms have been reviewed. The current review investigates the approaches working on utilizing genetically modified micro-organisms and effective removal techniques.

Human health risk assessment of heavy metal and pathogenic contamination in surface water of the Punnakayal estuary, South India.

Variation in levels of toxic heavy metals in river system during the COVID-19 pandemic lockdown might potentially assist in development of a public health risk mitigation system associated with the water consumption. The water quality of Punnakayal estuary in the Thamirabarani River system from the south India, a vital source of water for drinking and domestic purposes, industrial usage, and irrigation was assessed here. A comparitive assessment of physico-chemical variables (pH, EC, TDS, DO, BOD, turbidity and NO3), microbiological parameters (total coliform bacteria, fecal coliform bacteria, fecal streptococci and escherichia coli) and toxic metals (As, Cr, Fe, Cu, Zn, Cd, and Pb) suggested a decrease of 20% in the contaminant ratio during the lockdown period in comparison to the pre-lockdown period. The Health risk assessment models (HQ, HI, and TCR) highlighted carcinogenic and non-carcinogenic hazards for both children and adults through the ingestion and dermal adsorption exposures. The HI values for both As and Cr exceeded the acceptable limit (>1) during the lockdown period, but the potential risk for children and adults remained low in compaisio with the pre-lockdown period. Our results suggested that the Thamirabarani River system remained hostile to human health even during the lockdown period, and it requires regular monitoring through a volunteer water quality committee with private and government participations.

Assessment of Toxic Metals (Al, Cd, Pb) and Trace Elements (B, Ba, Co, Cr, Cu, Fe, Mn, Mo, Li, Zn, Ni, Sr, V) in the Common Kestrel (Falco tinnunculus) from the Canary Islands (Spain).

The monitoring of trace elements and toxic metals in apical predators of the trophic chain provides data on the degree of contamination in ecosystems. The common kestrel is one of the most interesting raptors in this respect in the Canary Islands; therefore, the study of the levels of trace elements and toxic metals in this species is of much scientific value. The content of trace elements and toxic metals (B, Ba, Co, Cr, Cu, Fe, Mn, Mo, Li, Zn, Ni, Sr, V, Al, Cd, Pb) was determined in the liver, muscle, and feathers of 200 specimens of common kestrel carcasses (Falco tinnunculus canariensis) from Tenerife. Cr (0.82 ± 2.62 mg/kg), Cu (11.82 ± 7.77 mg/kg), and Zn (198.47 ± 520.80 mg/kg) are the trace elements that stand out in the feather samples; this may be due to their affinity for the pigments that give them their coloring. Li was noteworthy in the liver samples (8.470 ± 5.702 mg/kg). Pb stood out in the feathers (4.353 ± 20.645 mg/kg) > muscle (0.148 ± 0.095 mg/kg) > liver (0.187 ± 0.133 mg/kg). The presence of metals in feathers correlates with recent exposure and reflects environmental contamination. When using raptor feathers as indicators of metal contamination, it is important to know what the levels of each metal signify. The analysis of the different tissues and organs of raptors, such as the common kestrel, provides valuable information on the degree of environmental contamination of the ecosystem in which it lives. Gender was not an influencing factor in this study.

Health risk assessment induced by trace toxic metals in tap drinking water: Condorcet principle development.

Acute exposure to trace metals (TMs) in water is hazardous to human health. The average concentrations (Cavg.) and carcinogenic (CAR) and non-carcinogenic (non-CAR) risks of eight TMs to World Health Organization's (WHO) guidelines and national standard limits (NSLs)were determined. The Cavg. and (the range) of As, Hg, Cd, Pb, Co, Cr, Ni, and Zn were measured as 4.29 ± 0.57 µg L-1 (1.12-10.27 µg L-1), 0.22 ± 0.10 µg L-1 (ND-1.05 µg L-1), 0.31 ± 0.18 µg L-1 (ND-1.80 µg L-1), 4.66 ± 0.32 µg L-1 (0.10-14.22 µg L-1), 24.61 ± 4.65 µg L-1 (3.11-67.25 µg L-1), 16.86 ± 5.54 µg L-1 (5.12-34.61 µg L-1), 14.07 ± 4.37 µg L-1 (3.79-31.39 µg L-1), and 268.42 ± 75.82 (87.29-561.22 µg L-1), respectively. The Cavg. of Co and Hg exceeded the WHO and NSLs. The non-CAR risk assessment was used to order the TMs according to the total target hazard quotient (TTHQ) As > Pb > Cr > Co > Zn > Hg > Ni > Cd. None of the investigated age groups are at risk As there is a low Cavg of all trace metals (i.e., the THQ is > 1). The age groups were ranked based on THQ and incremental lifetime cancer risk (ILCR) As < 1 year, >1-10 years, > 11-19 years, and > + 20 years. The ILCR of As for all the age groups was >10-4, whereas for Pb it was <10-6. Cumulative carcinogenic risk (CCR) for As and Pb was at a safe threshold risk (>10-4) for all the age groups.

Arsenic and toxic metals in meat and fish consumed in Niger delta, Nigeria: Employing the margin of exposure approach in human health risk assessment.

This study provides information on the health risk of As, Cd, Hg, Pb and V exposure from Nigerian foods consumption (fish, cow, goat and chicken meat) in different age-groups (children, adolescent, adult, senior) and six areas of Niger Delta, Nigeria (Choba, Khana, Eleme, TransAmadi, Uyo, and Yenogoa). The health risk assessment was performed by estimating the weekly or monthly intake of metals from foods and Margin of Exposure (MOE) approach by using established benchmark dose levels (BMDLs). Regarding As, cow and chicken meat products contributed to As exposure intake especially in children resulting in values higher than BMDL0.1 for cancer risk in TransAmadi and Uyo areas. Cadmium exposure was due to cow, chicken and goat meat ingestion mostly in adolescent above the tolerable monthly intake limit in TransAmadi and Uyo areas. Concerning Hg and V, the exposure from Nigerian food did not constitute a potential health hazard. Lead exposure in children were above or close to BMDL0.1 for developmental neurotoxicity by ingestion of cow and goat meat in all the Nigerian areas. In adult and senior the Pb dietary exposure were above the BMDL10 providing a low to negligible risk for kidney effects. The potential concern for health effects in Niger Delta population needs further efforts to decrease As, Cd and Pb dietary exposure especially for children and adolescent, who are more vulnerable to adverse life events.

Assessment of the release of metals from cigarette butts into the environment.

Cigarette butts are known to contain toxic metals which pose a potential threat to the environment and human health. The seriousness of this threat is largely determined by the leachability of these toxic metals when the butts are exposed to aqueous solutions in the environment. The aims of this study were to determine the presence and mobility of toxic and non-toxic elements found in discarded cigarette butts; to relate this mobility to two different contact situations with leaching liquids: tumbling and trampling (batch test) and percolation in a static position (column test); and finally, to verify possible variations in solubility by simulating different environmental systems. Five leachants with different pH values were used to simulate various environmental conditions The concentrations of the solubilized metals were determined by inductively coupled plasma-atomic emission spectrometry (ICP-AES) and inductively coupled plasma-mass spectrometry (ICP-MS). CH3COOH pH 2.5 showed the greatest capacity to dissolve many elements. On the contrary, weakly acidic or alkaline environments did not favor the leachability of the elements. The best extraction capacity of the column with respect to the batch is statistically significant (p <0.05) for the elements Al, Fe, Ni and Zn, while the batch for P, Si, S. Pb, Cd, As were not detectable in cigarette butts, while Hg had an average concentration of 0.0502 µg/g. However, Hg was < LOD in all different leachants.