RESUMO
PURPOSE: This study was carried out to characterize the clinical and histological changes in the cutaneous portion of the transferred pedicled pectoralis major myocutaneous flaps used in intraoral reconstruction in patients with head and neck malignancy. METHODS: This was a prospective cohort study carried out from July 2016 to 2018. All patients underwent ablative surgery for oropharyngeal cancers and primary reconstruction with pedicled pedicled pectoralis major myocutaneous flaps. The intraoral flaps were examined for color, texture, presence of hair, chronic inflammatory changes, and ulceration. At 12 months, incisional biopsies were taken from the skin paddle of the intraoral flap and contralateral normal buccal mucosa, and flap histology was compared with that of the contralateral buccal mucosa. RESULTS: Twenty patients were included in the final analysis (M/F, 4:1; mean ± SD age, 51.38 ± 6.76 years). Fourteen flaps resembled oral mucosa, 3 had a mixed appearance of both skin and mucosa, and 3 had appearance of normal skin at 1 year follow-up. The epidermis and stratum corneum were retained in all the flap biopsies; however, severe attenuation was noted in 7 patients (had mucosal appearance) but was significantly different from oral mucosa(P = 0.0003). Cutaneous appendages were found in all the flap epithelia. Thirteen flaps showed grossly attenuation, of which 11 patients had a gross appearance resembling oral mucosa and 2 had a mixed appearance. The biopsies showed varied degree of chronic changes like desquamation in around 35% (7 patients), hyperkeratosis in 35% (7 patients), and chronic candidiasis in 30% (6 patients). CONCLUSIONS: Although the intraorally transferred flaps demonstrate a morphological appearance similar to oral mucosa, there is a histological preservation of skin elements and architecture.
Assuntos
Retalho Miocutâneo/patologia , Retalho Miocutâneo/transplante , Neoplasias Orofaríngeas/cirurgia , Músculos Peitorais/transplante , Procedimentos de Cirurgia Plástica/métodos , Biópsia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Neoplasias Orofaríngeas/patologia , Estudos ProspectivosRESUMO
BACKGROUND: Prepectoral breast reconstruction following mastectomy has become a more widely performed technique in recent years because of its numerous benefits for women. These include full pectoralis muscle preservation, reduced loss of strength, reduced pain, and elimination of animation deformity. As with any breast reconstruction technique, widespread adoption is dependent on a low morbidity profile in the setting of postmastectomy radiation therapy, as this adjuvant therapy is routine in breast cancer treatment. The authors assess the clinical outcomes of patients undergoing postmastectomy radiation therapy following prepectoral breast reconstruction, and compare these to outcomes of patients undergoing postmastectomy radiation therapy with submuscular reconstruction. METHODS: A single surgeon's experience with immediate prepectoral breast reconstruction, followed by postmastectomy radiation therapy, from 2015 to 2017 was reviewed. Patient demographics and incidence of complications during the tissue expander stage were assessed. In addition, the morbidity profile of these patients was compared to that of patients undergoing submuscular/dual-plane reconstruction and postmastectomy radiation therapy over the same period. RESULTS: Over 3 years, 175 breasts underwent immediate prepectoral reconstruction, and 236 breasts underwent immediate submuscular/dual-plane reconstruction. Overall rates of adjuvant radiation therapy (postmastectomy radiation therapy) were similar between prepectoral [26 breasts (14.9 percent)] and submuscular [31 breasts (13.1 percent)] (p = 0.6180) reconstruction. There were no significant differences in complication rates between the two reconstructive cohorts, in the setting of postmastectomy radiation therapy, including rates of explantation (15.4 percent versus 19.3 percent; p = 0.695). CONCLUSIONS: Prepectoral breast reconstruction is a safe and effective option in the setting of postmastectomy radiation therapy. The morbidity profile is similar to that encountered with submuscular reconstruction in this setting. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III.
Assuntos
Neoplasias da Mama/radioterapia , Neoplasias da Mama/cirurgia , Mamoplastia/métodos , Mastectomia Subcutânea/métodos , Músculos Peitorais/transplante , Retalhos Cirúrgicos/transplante , Adulto , Estudos de Coortes , Bases de Dados Factuais , Estética , Feminino , Seguimentos , Rejeição de Enxerto , Sobrevivência de Enxerto , Humanos , Pessoa de Meia-Idade , Radioterapia Adjuvante , Estudos Retrospectivos , Resultado do Tratamento , Cicatrização/fisiologiaRESUMO
Free tissue transfer is the preferred reconstruction option in most major head and neck reconstructions. The pectoralis major muscle musculocutaneous (PMMC) flap is commonly used in salvage of necrotic free flaps and is the first choice for patients who are not candidates for free flaps. The lateral thoracic artery (LTA), which is thought to contribute to blood perfusion of the inferior and lateral mammary area, is not preserved in a conventionally harvested PMMC flap. With regard to blood supply, it has been suggested that the LTA should be preserved, in addition to the pectoral branch of the thoracoacromial artery, when a skin island is designed in the lower chest to attain a pedicle length sufficient for head and neck reconstruction. However, an effect on hemodynamic improvement using the LTA has not been shown quantitatively. In this study, we examined 8 patients with oral cancer who underwent reconstruction procedures with a bipedicle PMMC flap that included the LTA, in addition to the thoracoacromial artery. Intraoperative indocyanine green angiography was performed to examine circulation to the PMMC flap with or without LTA clamping after harvesting. After image processing, data were analyzed using a new quantitative perfusion assessment system with parameters that we recently established for assessment of peripheral arterial disease of the lower limbs. All patients had good clinical courses with whole-flap survival, no vascular insufficiency of the skin island, and no fistula formation. Intraoperative indocyanine green angiography showed an increased inflow rate into the skin island in an LTA-declamped condition in all cases, implying that the preserved LTA increased the blood supply to skin islands in the pectoralis major muscle. We conclude that preserving the LTA in a PMMC flap can increase blood perfusion and stabilize the vascularity of the flap, making the reconstruction more effective and reliable than with use of a conventionally harvested flap. Therefore, it is worthwhile to preserve the LTA as a major contributor to a lateral and distal PMMC flap.
Assuntos
Verde de Indocianina , Neoplasias Bucais/cirurgia , Retalho Miocutâneo/irrigação sanguínea , Músculos Peitorais/transplante , Artérias Torácicas/cirurgia , Idoso , Idoso de 80 Anos ou mais , Angiografia/métodos , Estudos de Avaliação como Assunto , Feminino , Sobrevivência de Enxerto , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Bucais/parasitologia , Retalho Miocutâneo/transplante , Músculos Peitorais/irrigação sanguínea , Prognóstico , Procedimentos de Cirurgia Plástica/métodos , Fluxo Sanguíneo Regional/fisiologia , Estudos Retrospectivos , Estudos de Amostragem , Artérias Torácicas/transplante , Coleta de Tecidos e Órgãos , Resultado do TratamentoRESUMO
PURPOSE: Starting from our experience with 45 consecutive cases of regional pedicled flaps, we have underlined the effectiveness and reliability of a variety of flaps. The marketing laws as applied to surgical innovations are reviewed to help in the understanding of why regional flaps are regaining wide popularity in head and neck reconstruction. MATERIALS AND METHODS: From January 2009 to January 2014, 45 regional flaps were harvested at San Paolo Hospital to reconstruct head and neck defects. These included 35 pectoralis major muscular and myocutaneous flaps, 4 lower trapezius island or pedicled flaps, 3 supraclavicular flaps, 2 latissimus dorsi pedicled flaps, and 1 fasciocutaneous temporal flap. The basic literature of marketing regarding the diffusion of new products was also reviewed. RESULTS: Two myocutaneous pectoralis major flaps were complicated by necrosis of the cutaneous paddle (one complete and one partial). No complete loss of any of the 45 flaps was observed. At 6 months of follow-up, 2 patients had died of multiple organ failure after prolonged sepsis. The 43 remaining patients had acceptable morphologic and functional results. CONCLUSIONS: Regional and free flaps appear to compete in many cases for the same indications. From the results of the present case series, regional flaps can be considered reliable reconstructive choices that are less expensive than their free flap alternatives. The "resurrection" of regional flaps can be partially justified by the changes in the global economy and the required adaptation of developed and developing countries.
Assuntos
Neoplasias de Cabeça e Pescoço/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Retalhos Cirúrgicos/transplante , Idoso , Transplante Ósseo/métodos , Carcinoma de Células Escamosas/cirurgia , Causas de Morte , Fáscia/transplante , Feminino , Seguimentos , Sobrevivência de Enxerto , Humanos , Masculino , Pessoa de Meia-Idade , Insuficiência de Múltiplos Órgãos/etiologia , Músculo Esquelético/transplante , Retalho Miocutâneo/transplante , Músculos Peitorais/transplante , Procedimentos de Cirurgia Plástica/economia , Estudos Retrospectivos , Couro Cabeludo/cirurgia , Sepse/complicações , Neoplasias Cutâneas/cirurgia , Transplante de Pele/métodos , Retalhos Cirúrgicos/economia , Músculo Temporal/transplante , Neoplasias da Língua/cirurgiaRESUMO
Our study investigated the quality of life (QoL) of Chinese patients after immediate reconstruction surgery on individuals with head and neck cancer. In addition, we compared the differences between pectoralis major myocutaneous flap (PMMF) and anterolateral thigh free flap (ALTFF). The University of Washington Quality of Life questionnaire, version 4, was used to assess the QoL. Assessments were performed at least 24 months postoperatively. A total of 110 patients' records were obtained. Among them, 86 patients completed a QoL questionnaire (78.2%). No significant differences could be found in age, primary site, T stage, N stage, and postoperative radiotherapy between PMMF and ALTFF groups. However, there were significant differences between both groups in sex, operation time, and complication. A matched analysis was performed to compare the differences in QoL between patients with head and neck cancers reconstructed with PMMF or ALTFF. Patients reconstructed with ALTFF had better shoulder but worse speech functions. There was a significant effect on the QoL of head and neck cancer patients who had undergone either PMMF or ALTFF reconstruction. The result of this study provide useful information for physicians and patients during their discussion of treatment modalities for head and neck cancers.
Assuntos
Neoplasias de Cabeça e Pescoço/cirurgia , Retalho Miocutâneo , Músculos Peitorais/transplante , Retalho Perfurante , Procedimentos de Cirurgia Plástica/métodos , Adulto , Idoso , Feminino , Retalhos de Tecido Biológico , Humanos , Masculino , Pessoa de Meia-Idade , Qualidade de Vida , Estudos Retrospectivos , Fala , Inquéritos e Questionários , Coxa da Perna/cirurgia , Transplante de Tecidos/métodos , Adulto JovemRESUMO
PURPOSE: The aim of the present study was to evaluate the quality of life (QoL) of patients with oral cancer who had undergone resection of the tongue and floor of the mouth and reconstruction with the pectoralis major flap. MATERIALS AND METHODS: The present study assessed 21 patients who had undergone pectoralis major flap reconstruction using the University of Washington QoL, version 4, questionnaire. A nonparametric Mann-Whitney U test was used to analyze the data. RESULTS: Of the 12 disease-specific domains, the best 3 scores from the patients were for pain, saliva, and anxiety, and the worst 3 scores were for taste, chewing, and swallowing. The mean UW-QoL composite score was 73.4. Swallowing was considered to be the most important issue within the previous 7 days, followed by chewing and speech. Those patients who had undergone wider excision had poorer speech. CONCLUSIONS: A significant effect was found on the QoL of patients with oral cancer who had undergone resection of the tongue and floor of the mouth with pectoralis major flap reconstruction.
Assuntos
Neoplasias Bucais/cirurgia , Retalho Miocutâneo/transplante , Músculos Peitorais/transplante , Procedimentos de Cirurgia Plástica/psicologia , Qualidade de Vida , Fala/fisiologia , Adulto , Idoso , Ansiedade/psicologia , Atitude Frente a Saúde , Deglutição/fisiologia , Seguimentos , Glossectomia/métodos , Sobrevivência de Enxerto , Humanos , Masculino , Mandíbula/cirurgia , Mastigação/fisiologia , Pessoa de Meia-Idade , Soalho Bucal/cirurgia , Neoplasias Bucais/psicologia , Esvaziamento Cervical , Estadiamento de Neoplasias , Medição da Dor , Radioterapia Adjuvante , Saliva/fisiologia , Paladar/fisiologia , Coleta de Tecidos e Órgãos/métodos , Neoplasias da Língua/cirurgiaRESUMO
INTRODUCTION: The pectoralis major myocutaneous flap (PMMF) is commonly used for oral cavity reconstruction, yet its impact on function (intelligible speech, swallowing, mastication, tongue mobility, oral competence, and mouth opening) has rarely been studied or reported in the literature. PURPOSE: This study assessed the long-term functional outcome of oral cavity reconstruction with PMMF, placing particular emphasis in its correlation with size of the skin paddle and volume of the flap. MATERIALS AND METHODS: Twenty-five patients who underwent reconstruction of compound defects of the oral cavity that involved floor of mouth, buccal mucosa, alveolar ridge, retromolar area, lateral tongue, and continuity of mandible were assessed and followed up for up to 4 years. Assessment of function was based on predetermined clinical parameters along with consecutive measurements of skin paddle size. RESULTS: At 6 months, the size of the skin paddles averaged a 37% decrease in size, along with a marked reduction in the mass effect from the flap. Tongue mobility was considered good in all patients. Speech was considered intelligible in 84% of patients, of which 16% required some concentration to understand. Initial complaints of difficulty swallowing resolved in every patient and mouth opening in all patients returned to their preoperative state. These findings were maintained consistently throughout the follow-up period. Flap complications, consisting of partial skin paddle necrosis, occurred in 4 patients (16%), but healed after local debridement. Intraoral hair in the skin paddle was present in 5 men who did not receive postoperative radiotherapy. CONCLUSIONS: Reconstruction of the oral cavity (including defects with partial involvement of the tongue and continuity of mandible) can be predictably accomplished using PMMF. These procedures are associated mostly with minor and temporary disruption of function and quality of life and few complications.
Assuntos
Doenças da Boca/cirurgia , Músculos Peitorais/transplante , Procedimentos de Cirurgia Plástica/métodos , Retalhos Cirúrgicos , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Recuperação de Função Fisiológica , Inteligibilidade da Fala , Resultado do TratamentoRESUMO
OBJECTIVES: The free radial forearm flap has replaced the pedicled pectoralis major myocutaneous flap and it has become the 'workhorse flap' used by many head and neck reconstructive surgeons for soft tissue reconstructions. Cost implications of radial forearm flap reconstruction within the context of the overall health care in a particular system need to be investigated particularly before it is labelled as 'costly only'. DESIGN AND SETTING: Forty patients who underwent immediate free radial forearm flap reconstruction for oral or oropharyngeal soft tissue defects were matched with patients who underwent pectoralis major myocutaneous flap reconstruction for similar defects. The 2 years of which the overall management costs according to the hospital perspective were calculated were divided into four periods: operative period, the postoperative phase, follow-up during first year and follow-up during second year after discharge. RESULTS: The total costs within the first 2 years were comparable at approximately 50,000 Euros. The lower costs of hospital admission (24 days versus 28 days; P = 0.005) in the postoperative phase outweighed the higher costs of the surgical procedure (692 min versus 462 min; P < 0.005) in radial forearm flap patients when compared with pectoralis major flap patients. CONCLUSIONS: Oral and oropharyngeal reconstruction with radial forearm flap is not more costly than pectoralis major flap reconstruction. Given the better functional outcome and the present cost analysis, reconstruction of oral and oropharyngeal defects is preferably performed using free tissue transfer.
Assuntos
Antebraço/irrigação sanguínea , Neoplasias de Cabeça e Pescoço/cirurgia , Músculos Peitorais/irrigação sanguínea , Músculos Peitorais/transplante , Procedimentos de Cirurgia Plástica/economia , Procedimentos de Cirurgia Plástica/métodos , Retalhos Cirúrgicos , Idoso , Estudos de Casos e Controles , Distribuição de Qui-Quadrado , Custos e Análise de Custo , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estatísticas não Paramétricas , Resultado do TratamentoRESUMO
This study analyzes the postoperative complications and the functional results in 61 patients who underwent total laryngectomy with partial or total (circumferential) pharyngectomy reconstructed with a pectoralis major myocutaneous flap, in relation to the use of the Montgomery Salivary Bypass Tube (MSBPT). There were no significant differences regarding frequency of postoperative cervical complications in relation to the use of the MSBPT. The median hospital stay for patients without the MSBPT (36 days) was significantly higher than that for patients with the MSBPT (25 days). Although the MSBPT did not modify the rate of complications at the cervical level, it did reduce their severity. A financial study showed the cost-effectiveness of using the MSBPT. Systematic use of the MSBPT is recommended after total laryngectomy with partial or total pharyngectomy reconstructed with a pectoralis major myocutaneous flap.
Assuntos
Carcinoma de Células Escamosas/cirurgia , Neoplasias Hipofaríngeas/cirurgia , Procedimentos de Cirurgia Plástica/economia , Glândulas Salivares/cirurgia , Adulto , Idoso , Anastomose Cirúrgica , Análise Custo-Benefício , Desenho de Equipamento , Estudos de Avaliação como Assunto , Feminino , Humanos , Laringectomia/métodos , Masculino , Pessoa de Meia-Idade , Músculos Peitorais/transplante , Faringectomia/métodos , Complicações Pós-Operatórias , Procedimentos de Cirurgia Plástica/instrumentação , Procedimentos de Cirurgia Plástica/métodos , Estudos RetrospectivosRESUMO
A series of 178 immediate reconstructions with regional or distant tissue for repair of oropharyngeal defects caused by treatment of head and neck cancer was reviewed to determine whether reconstruction with free flaps was more or less expensive than reconstruction with regional myocutaneous flaps. In this series, three types of flaps were used: the radial forearm free flap (n = 89), the rectus abdominis free flap (n = 56), and the pectoralis major myocutaneous flap (n = 33). Resource costs were determined by adding all costs to the institution of providing each service studied using salaried employees (including physicians). The two free-flap groups were combined to compare free flaps with the pectoralis major myocutaneous flap, a regional myocutaneous flap. Failure rates in the two groups were similar (3.0 percent for pectoralis major myocutaneous flap, 3.4 percent for free flaps). The mean costs of surgery were slightly higher for the free flaps, but the subsequent hospital stay costs were lower. Therefore, the total mean resource cost for the free-flap group ($28,460) was lower than the cost for the myocutaneous flap group ($40,992). The pectoralis major myocutaneous flap may have been selected for more patients with advanced disease and systemic medical problems, contributing to longer hospitalization and added cost. Nevertheless, this study suggests that free flaps are not more expensive than other methods and may provide cost savings for selected patients.
Assuntos
Neoplasias de Cabeça e Pescoço/cirurgia , Custos Hospitalares , Músculos Peitorais/transplante , Retalhos Cirúrgicos/economia , Fatores Etários , Análise de Variância , Redução de Custos , Antebraço , Sobrevivência de Enxerto , Hospitalização/economia , Humanos , Tempo de Internação/economia , Pessoa de Meia-Idade , Doenças da Boca/etiologia , Doenças da Boca/cirurgia , Músculo Esquelético/transplante , Orofaringe/cirurgia , Doenças Faríngeas/etiologia , Doenças Faríngeas/cirurgia , Médicos/economia , Complicações Pós-Operatórias/cirurgia , Reto do Abdome/transplante , Estudos Retrospectivos , Salários e Benefícios , Transplante de Pele/economia , Retalhos Cirúrgicos/métodos , Fatores de TempoRESUMO
Thirty-nine patients underwent reconstruction of composite mandibular defects following resection for squamous cell carcinoma. Thirty-four underwent immediate reconstruction, while 5 were reconstructed secondarily. Twenty-one received soft-tissue reconstruction only with a pectoralis major myocutaneous flap, 14 underwent osteocutaneous free-tissue transfer, and 4 received a reconstruction plate with free-tissue transfer for soft-tissue coverage. The mandibular defects in the pectoralis major myocutaneous flap group tended to be posterolateral, while free-tissue transfer defects were more severe, usually involving the anterior mandible. Length of surgery and duration of intensive care unit care were significantly longer for free-tissue transfer patients, while flap complications were more common in the pectoralis major myocutaneous flap patients. Facial appearance scores were higher for the free-tissue transfer group by both patient and physician assessment. Social function, speech, and oral function did not differ significantly. Patients reconstructed secondarily with free-tissue transfer reported significant improvement in appearance, oral continence, and social function, with little change in speech intelligibility, deglutition, or diet tolerance. The cost of the main hospitalization was significantly higher in the free-tissue transfer group than in the pectoralis major myocutaneous flap group, although when the costs of subsequent hospitalizations are included, the difference in total cost narrows. Despite more adverse defects, free-tissue transfer provided more predictable aesthetic results and expeditious return to normal social function than did pectoralis major myocutaneous flap reconstruction. The fiscal impact of these complex reconstructions is, however, significant. Cost-containment issues are presented and recommendations are made.
Assuntos
Transplante Ósseo/métodos , Carcinoma de Células Escamosas/cirurgia , Mandíbula/cirurgia , Neoplasias Mandibulares/cirurgia , Músculos Peitorais/transplante , Transplante de Pele/métodos , Retalhos Cirúrgicos/métodos , Idoso , Placas Ósseas , Transplante Ósseo/efeitos adversos , Transplante Ósseo/economia , Carcinoma de Células Escamosas/reabilitação , Controle de Custos , Cuidados Críticos , Deglutição , Dieta , Estética , Face/anatomia & histologia , Feminino , Custos Hospitalares , Hospitalização/economia , Humanos , Tempo de Internação , Masculino , Neoplasias Mandibulares/reabilitação , Pessoa de Meia-Idade , Boca/fisiologia , Satisfação do Paciente , Transplante de Pele/efeitos adversos , Transplante de Pele/economia , Ajustamento Social , Fala , Inteligibilidade da Fala , Retalhos Cirúrgicos/efeitos adversos , Retalhos Cirúrgicos/economia , Resultado do TratamentoRESUMO
The prime objective of oral cavity reconstruction is restoration of function, which must be carefully studied while evaluating the success of any reconstructive endeavour. We devised a unique comprehensive test series for the purpose that is suitable for use in routine follow-ups, and capable of providing objective documentation. Functional assessment included evaluation of general health, food intake, oral competence, mastication, speech, swallowing, tongue mobility, and shoulder-neck function. Fifty patients who had surgery were analyzed and their functional scores compared with those of 10 normal volunteers. The extent of mandibular resection and the magnitude of soft tissue excision significantly affected overall scores of function. Oral competence, as reflected by the water holding test (WHT), was uniformly impaired in the 50 patients, and in dentate individuals, the quality of bolus provided good correlation with all other functional scores. Among reconstructive modalities employed here, the bi-paddled pectoralis major flap produced the best overall scores.
Assuntos
Neoplasias Bucais/reabilitação , Neoplasias Bucais/cirurgia , Boca/fisiopatologia , Boca/cirurgia , Adulto , Deglutição/fisiologia , Ingestão de Alimentos/fisiologia , Feminino , Humanos , Masculino , Mandíbula/cirurgia , Mastigação/fisiologia , Pessoa de Meia-Idade , Movimento , Pescoço/fisiopatologia , Esvaziamento Cervical/reabilitação , Músculos Peitorais/fisiopatologia , Músculos Peitorais/transplante , Ombro/fisiopatologia , Fala/fisiologia , Inteligibilidade da Fala/fisiologia , Retalhos Cirúrgicos/efeitos adversos , Língua/fisiopatologiaRESUMO
Because of increasing concerns about the high cost of complex medical care, we compared the combined cost of ablation and reconstruction incurred using five different management strategies for patients undergoing mandibular resection. We also compared the rates of complication and failure for the methods used. The records of 69 patients undergoing segmental or total mandibulectomy between January 1, 1986, and June 30, 1990, were reviewed. Of these, 15 had reconstruction with soft tissue only (average cost, $36,137; complication rate, 33%), whereas 20 had immediate reconstruction with vascularized bone (average cost, $46,894; complication rate, 50%), and 15 had reconstruction with only a metal plate (average cost, $47,678; complication rate, 73%). Nine patients had plate reconstructions initially but subsequently underwent reconstructions with bone (average cost, $54,346; complication rate, 78%), whereas 10 patients had no initial reconstruction but subsequently underwent delayed reconstruction with bone (average cost, $52,486; complication rate, 70%). If reconstruction was performed with bone, immediate reconstruction was more cost effective than delayed reconstruction and had a lower complication rate as well.