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1.
Semin Reprod Med ; 19(4): 339-54, 2001 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-11727176

RESUMO

The experience of 6 million Norplant users has led to several more advanced implants. Implanon is a single-rod implant system containing a low androgenic progestin and requires 1 to 2 minutes for insertion and removal. Like other implants, Implanon prevents pregnancy by changing the character of the cervical mucus and interfering with luteal function. Unlike Norplant, though, Implanon is designed to prevent ovulation for the full duration of use. Implant contraception has several advantages over other types of contraception including high efficacy, minimal required maintenance, absence of estrogen, and rapid return of fertility after discontinuation. Implants can be a good choice for adolescents; women with hypertension, diabetes, anemia, endometriosis, or other medical problems; and women who are breast-feeding. Irregular bleeding is the most common adverse effect of implants and can be treated with several medication regimens. Preinsertion counseling, however, is the most important factor in ensuring satisfaction with implants. Unfortunately, no implant system is currently available in the United States since August 2000, but Implanon is expected to reach the U.S. market within the next 2 years.


Assuntos
Anticoncepcionais Femininos/administração & dosagem , Desogestrel , Implantes de Medicamento/administração & dosagem , Megestrol/análogos & derivados , Congêneres da Progesterona/administração & dosagem , Muco do Colo Uterino/efeitos dos fármacos , Ensaios Clínicos como Assunto , Anticoncepcionais Femininos/economia , Anticoncepcionais Femininos/farmacologia , Aconselhamento , Endométrio/efeitos dos fármacos , Feminino , Humanos , Levanogestrel/administração & dosagem , Levanogestrel/farmacologia , Megestrol/administração & dosagem , Megestrol/farmacologia , Norprogesteronas/administração & dosagem , Norprogesteronas/farmacologia , Ovulação/efeitos dos fármacos , Satisfação do Paciente , Gravidez , Congêneres da Progesterona/economia , Congêneres da Progesterona/farmacologia , Ensaios Clínicos Controlados Aleatórios como Assunto , Fatores de Risco , Compostos de Vinila/administração & dosagem , Compostos de Vinila/farmacologia
2.
Obstet Gynecol Clin North Am ; 27(4): 781-815, 2000 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-11091988

RESUMO

Although levonorgestrel contraceptive implants have been available for over 15 years, innovations have only recently led to a wider choice. These new implants offer easier insertion and removal and other advantages depending on the type of progestin. Implants prevent pregnancy by several mechanisms, including inhibition of ovulation and luteal function and alteration of cervical mucus and the endometrium. The high efficacy and ease of maintenance make implants an ideal contraceptive for many women, including adolescents, a population that uses implants infrequently but reports high satisfaction. Implants are appropriate for women who are breastfeeding, who have contraindications to estrogen, or who have diseases such as diabetes, hypertension, sickle cell anemia, or an HIV infection because implants have few metabolic or hematologic effects. Long-term use has not been associated with a decrease in BMD and generally leads to increased blood levels and iron stores. Women who wish to space their pregnancies appreciate the nearly immediate onset of action with insertion and the rapid termination of all effects with removal. All types of implants lead to menstrual changes and other side effects in some women. Adverse effects that occur in implant users more than the general population include headaches and acne. Women must be thoroughly counseled regarding the potential for menstrual alteration, side effects, and sexually transmitted infections if they do not use condoms. Despite their initial high cost, implants are a cost-effective method over several years, even when discontinued before the life of the implant.


Assuntos
Anticoncepcionais Femininos/administração & dosagem , Implantes de Medicamento , Adolescente , Muco do Colo Uterino/efeitos dos fármacos , Anticoncepcionais Femininos/efeitos adversos , Anticoncepcionais Femininos/farmacologia , Custos de Medicamentos , Feminino , Humanos , Ovulação/efeitos dos fármacos , Satisfação do Paciente , Gravidez , Congêneres da Progesterona/administração & dosagem , Congêneres da Progesterona/efeitos adversos , Congêneres da Progesterona/farmacologia
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