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1.
Injury ; 54(2): 280-287, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36586813

RESUMO

INTRODUCTION: Iliopsoas hematoma with femoral nerve palsy is a rare phenomenon with no consensus treatment algorithm. The objective of this study was to perform a systematic review of all reported cases of femoral nerve palsy secondary to iliopsoas hematoma to better elucidate it's optimal treatment. MATERIALS AND METHODS: Queries of the PubMed, Embase, and Cochrane databases were performed for reports available in English of femoral nerve palsy secondary to iliopsoas, psoas, or iliacus hematoma. 1491 articles were identified. After removal of duplicated publications and review of abstract titles via a majority reviewer consensus, 217 articles remained for consideration. Dedicated review of the remaining articles (including their reference sections) yielded 122 articles representing 174 distinct cases. Clinical data including patient age, sex, medical history, use of pharmacologic anticoagulation, sensory and motor examination at presentation and follow-up, hematoma etiology and location, time to intervention, and type of intervention were collected. Descriptive statistics were generated for each variable. RESULTS: Femoral nerve palsy secondary to iliopsoas hematoma occurred at a mean age of 44.5 years old. A majority of patients (60%) were male, and a majority of hematomas (54%) occurred due to pharmacologic anticoagulation. Most hematomas (57%) were treated conservatively, and almost half (49%) - regardless of treatment modality - resulted in persistent motor deficits at final follow-up. A minority of patients treated surgically (34%) had residual motor deficit at final follow-up, while 66% of those treated medically had resultant motor deficits, although no direct statistical comparison was able to be performed. DISCUSSION AND CONCLUSIONS: The disparate available data on iliopsoas hematoma with femoral nerve palsy precludes the completion of a true metanalysis, and therefore any conclusions on an optimal treatment algorithm. Based on review of the literature, small to moderate hematomas are often treated conservatively, while larger hematomas with progressive neurological symptoms are usually managed with a percutaneous decompression or surgery. LEVEL OF EVIDENCE: IV.


Assuntos
Nervo Femoral , Músculos Psoas , Humanos , Masculino , Feminino , Adulto , Hematoma/epidemiologia , Hematoma/cirurgia , Paralisia , Anticoagulantes/efeitos adversos
2.
Eur Spine J ; 31(7): 1658-1666, 2022 07.
Artigo em Inglês | MEDLINE | ID: mdl-35532816

RESUMO

PURPOSE: To assess whether saphenous somatosensory-evoked potentials (saphSSEP) monitoring may provide predictive information of femoral nerve health during prone lateral interbody fusion (LIF) procedures. METHODS: Intraoperative details were captured prospectively in consecutive prone LIF surgeries at a single institution. Triggered electromyography was used during the approach; saphSSEP was monitored throughout using a novel system that enables acquisition of difficult signals and real-time actionable feedback facilitating intraoperative intervention. Postoperative neural function was correlated with intraoperative findings. RESULTS: Fifty-nine patients (58% female, mean age 64, mean BMI 32) underwent LIF at 95 total levels, inclusive of L4-5 in 76%, fixated via percutaneous pedicle screws (81%) or lateral plate, with direct decompression in 39%. Total operative time averaged 149 min. Psoas retraction time averaged 16 min/level. Baseline SSEPs were unreliable in 3 due to comorbidities in 2 and anesthesia in 1; one of those resulted in transient quadriceps weakness, fully recovered at 6 weeks. In 25/56, no saphSSEP changes occurred, and none had postoperative femoral nerve deficits. In 24/31 with saphSSEP changes, responses recovered intraoperatively following intervention, with normal postoperative function in all but one with delayed quadriceps weakness, improved at 4 months and recovered at 9 months, and a second with transient isolated anterior thigh numbness. In the remaining 7/31, saphSSEP changes persisted to close, and resulted in 2 transient isolated anterior thigh numbness and 2 combined sensory and motor femoral nerve deficits, both resolved at between 4 and 8 months. CONCLUSIONS: SaphSSEP was reliably monitored in most cases and provided actionable feedback that was highly predictive of neurological events during LIF. LEVEL OF EVIDENCE: Diagnostic: individual cross-sectional studies with consistently applied reference standard and blinding.


Assuntos
Nervo Femoral , Fusão Vertebral , Estudos Transversais , Potenciais Somatossensoriais Evocados , Feminino , Humanos , Hipestesia , Vértebras Lombares/cirurgia , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fusão Vertebral/efeitos adversos , Fusão Vertebral/métodos
4.
Ulus Travma Acil Cerrahi Derg ; 26(1): 109-114, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31942744

RESUMO

BACKGROUND: Hip fracture is a common clinical problem which causes severe pain in geriatric patients. However, severe pain following fracture may bring on mental disorders and delirium. A neuroinflammatory response with IL-6 and IL-8 has been shown to be associated with the pathophysiology of delirium. In this study, our primary hypothesis is that preoperative femoral nerve block (FNB) intervention in geriatric patients will more effectively attenuate pain following trochanteric femur fracture than the preoperative paracetamol application. Our secondary hypothesis is that interleukin levels (IL-6, IL-8) in cerebrospinal fluid (CSF) will be lower in the femoral nerve block group than the paracetamol group. Our tertiary hypothesis is that the incidence of postoperative delirium will be lower in the femoral nerve block group. METHODS: The patients over 65 years of age with ASA status II-IV and admitted to the Emergency Service for femur fracture were included in this study. Recommendations of the 'delirium prevention table' were applied to all of the patients at arrival. In the first group, 15 mg/kg paracetamol was administered intravenously every eight hours. In the second group, femoral nerve blockage was performed, and a catheter was placed. Then, 0.5 mL/kg bupivacaine 0.25% was applied every eight hours. In both groups, pain scores four hours after interventions were recorded. All patients were operated within 48 hours under spinal anesthesia. During spinal anesthesia, 2 mL of CSF samples were taken from all patients for analysis of IL-6 and IL-8 cytokines, and pain scores during positioning were recorded. RESULTS: VAS scores four hours after the first preoperative pain treatment and during the positioning for regional anesthesia were significantly lower in the femoral nerve block group. IL-8 levels are significantly lower in the femoral nerve block group but not in IL-6 levels. The incidence of delirium was less in the femoral nerve block group, but the difference was not statistically significant. CONCLUSION: The femoral nerve block was more effective in preoperative pain management of trochanteric femur fracture and preventing pain during regional anesthesia application. The mean IL-8 level was lower in the femoral nerve block group when compared to the paracetamol group. There is no difference in the postoperative delirium incidence between groups.


Assuntos
Delírio , Nervo Femoral/fisiologia , Fraturas do Quadril/cirurgia , Bloqueio Nervoso/métodos , Manejo da Dor/métodos , Dor Pós-Operatória , Idoso , Idoso de 80 Anos ou mais , Delírio/epidemiologia , Delírio/etiologia , Delírio/prevenção & controle , Feminino , Humanos , Masculino , Dor Pós-Operatória/complicações , Dor Pós-Operatória/tratamento farmacológico
5.
Top Companion Anim Med ; 36: 1-3, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31472722

RESUMO

This study aimed to evaluate femoral nerve latency time recorded from both vastus lateralis and vastus medialis muscles, in clinically healthy dogs. Eighteen adult dogs were distributed into 2 distinct body mass ranges (Group 1: 1-4.1 kg, n= 9; Group 2: 4.2-13 kg, n= 8), according to the median body mass (4.1 kg). Distal motor latencies for the femoral nerve were obtained in right- and left hind limbs. Platinum surface electrodes were used to record the latency of femoral nerve from the vastus lateralis muscle, whereas coaxial needle electrodes were used to record the latency from the vastus medialis muscle. The distal motor nerve latencies were 1.52 ± .23 milliseconds and 1.69 ± .42 milliseconds, respectively, for vastus lateralis and vastus medialis muscles. There were no significant differences of distal motor nerve latencies between vastus lateralis and vastus medialis muscles. Hind limb length of Group 1 was significant shorter than Group 2. There were no significant differences of latencies between Groups 1 and 2. No significant correlations were observed between latency and body mass, and between latency and hind limb length for dogs of both groups. In conclusion, the femoral motor latency measurement was easy to obtain and may supply additional data in the examination of diseases that affect the hind limbs. Latency values of vastus lateralis longer than 1.52 ± .23 milliseconds in small/medium-sized breeds may be considered as suggestive of a femoral neuropathy.


Assuntos
Cães/fisiologia , Nervo Femoral/fisiologia , Extremidade Inferior/inervação , Músculo Quadríceps/inervação , Animais , Peso Corporal , Feminino , Extremidade Inferior/anatomia & histologia , Masculino , Condução Nervosa/fisiologia
6.
Eur Radiol ; 29(11): 5910-5919, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30980123

RESUMO

OBJECTIVES: To quantitatively characterize diabetic amyotrophy (DA), or diabetic lumbosacral radiculoplexopathy, and compare with controls using magnetic resonance neurography (MRN). METHODS: Forty controls and 23 DA cases were analyzed qualitatively and quantitatively. Cross-sectional areas (CSAs) of bilateral L3 through S2 lumbosacral nerve roots, femoral nerves, and sciatic nerves (proximal and distal measurements) were measured. A linear model was used to assess the nerve location and case/control effect on angle-corrected CSAs. Intra- and inter-reader analysis was performed using intraclass correlation (ICC). RESULTS: In DA cases, abnormalities of the lumbosacral nerve roots, sciatic, femoral, and obturator nerves were seen in 21/23, 16/23, 21/23, and 9/23, respectively. Denervation abnormalities of multiple abdominopelvic muscles were seen. Quantitatively, the CSA of all measured LS plexus nerve roots and bilateral femoral nerves were significantly larger in DA cases vs. controls by 45% (95% CI, (30%, 49%); p < 0.001). The ICC was moderate for inter-rater analysis = 0.547 (95% CI, 0.456-0.626) and excellent for intra-rater analysis = 0.90 (95% CI, 0.89-92). CONCLUSIONS: Multifocal neuromuscular lesions related to diabetic amyotrophy were qualitatively and quantitatively detected on MRN. Qualitative abnormalities distinguished cases from controls, and nerve CSAs of cases were significantly larger than those of controls. Therefore, MRN may be employed as a non-invasive diagnostic tool for the evaluation of diabetic amyotrophy. KEY POINTS: • Qualitative abnormalities of lumbosacral nerve roots, their peripheral branches, and muscles are seen in DA. • The lumbosacral nerve roots and their peripheral branches in diabetic amyotrophy cases are significantly larger in cross-sectional area than non-diabetic subjects by 45% (95 CI, 30%, 49%; p < 0.001). • The ICC was moderate for inter-rater analysis = 0.547 (95% CI, 0.456-0.626) and excellent for intra-rater analysis = 0.90 (95% CI, 0.89-92).


Assuntos
Neuropatias Diabéticas/diagnóstico , Nervo Femoral/patologia , Plexo Lombossacral/patologia , Imageamento por Ressonância Magnética/métodos , Nervo Isquiático/patologia , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos
7.
Plast Reconstr Surg ; 143(3): 771-778, 2019 03.
Artigo em Inglês | MEDLINE | ID: mdl-30601328

RESUMO

BACKGROUND: Donor nerve myelinated axon counts correlate with functional outcomes in reanimation procedures; however, there exists no reliable means for their intraoperative quantification. In this article, the authors report a novel protocol for rapid quantification of myelinated axons from frozen sections, and demonstrate its applicability to surgical practice. METHODS: The impact of various fixation and FluoroMyelin Red staining strategies on resolved myelin sheath morphology from cryosections of rat and rabbit femoral and sciatic nerves was assessed. A protocol comprising fresh cryosection and rapid staining was developed, and histomorphometric results were compared against conventional osmium-postfixed, resin-embedded, toluidine blue-stained sections of rat sciatic nerve. The rapid protocol was applied for intraoperative quantification of donor nerve myelinated axon count in a cross-facial nerve grafting procedure. RESULTS: Resolution of myelinated axon morphology suitable for counting was realized within 10 minutes of tissue harvest. Although mean myelinated axon diameter appeared larger using the rapid fresh-frozen as compared to conventional nerve processing techniques (mean ± SD; rapid, 9.25 ± 0.62 µm; conventional, 6.05 ± 0.71 µm; p < 0.001), no difference in axon counts was observed on high-power fields (rapid, 429.42 ± 49.32; conventional, 460.32 ± 69.96; p = 0.277). Whole nerve myelinated axon counts using the rapid protocol herein (8435.12 ± 1329.72) were similar to prior reports using conventional osmium processing of rat sciatic nerve. CONCLUSIONS: A rapid protocol for quantification of myelinated axon counts from peripheral nerves using widely available equipment and techniques has been described, rendering possible intraoperative assessment of donor nerve suitability for reanimation.


Assuntos
Expressão Facial , Nervo Facial/transplante , Paralisia Facial/cirurgia , Transferência de Nervo/métodos , Coloração e Rotulagem/métodos , Animais , Axônios/patologia , Axônios/transplante , Tomada de Decisão Clínica/métodos , Análise Custo-Benefício , Nervo Facial/citologia , Nervo Facial/patologia , Nervo Femoral/citologia , Nervo Femoral/patologia , Corantes Fluorescentes , Secções Congeladas , Humanos , Modelos Animais , Bainha de Mielina/patologia , Transferência de Nervo/economia , Transferência de Nervo/instrumentação , Coelhos , Ratos , Ratos Wistar , Nervo Isquiático/citologia , Nervo Isquiático/patologia , Coloração e Rotulagem/economia , Coloração e Rotulagem/instrumentação , Fatores de Tempo , Resultado do Tratamento
8.
Head Neck ; 40(7): 1356-1365, 2018 07.
Artigo em Inglês | MEDLINE | ID: mdl-29443415

RESUMO

BACKGROUND: The anterolateral thigh (ALT) free flap has been an extremely versatile flap. The purpose of this study was to propose comprehensive functional assessments of the donor site. METHODS: A total of 33 ALT flaps were enrolled prospectively. Objective assessments included isokinetic testing of the knee, and electromyographic examination of the lateral femoral cutaneous nerve (LFCN). The Patient and Observer Scar Assessment Scale (POSAS) was used to subjectively assess the donor-site scar. RESULTS: On the donor side, a significant decrease in most isokinetic muscle strength values was obvious 1 year postoperatively (P < .01). The normal side showed a compensatory increase 1 year postoperatively in the majority of isokinetic muscle strength values (P < .05). The majority of patients (70%) showed decreased sensory conduction velocity of the LFCN or no response to the microcurrent stimulation postoperatively. The aesthetic outcome was satisfactory. CONCLUSION: The decline in functional parameters at the donor-site was common. However, much more research is needed.


Assuntos
Nervo Femoral/fisiopatologia , Retalhos de Tecido Biológico , Força Muscular/fisiologia , Condução Nervosa/fisiologia , Sítio Doador de Transplante/fisiopatologia , Adulto , Idoso , Eletromiografia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Coxa da Perna
9.
Am J Vet Res ; 78(4): 412-420, 2017 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-28346000

RESUMO

OBJECTIVE To evaluate the potential efficacy of blind perineural injection techniques to provide nerve blockade of the saphenous, obturator, and lateral cutaneous femoral nerves by assessing the distribution along those nerves of 3 volumes of an injected staining solution in dog cadavers. ANIMALS 18 canine cadavers. PROCEDURES The anatomic characteristics of the target nerves were evaluated by dissection in 3 cadavers. The saphenous nerve was located by the use of superficial anatomic landmarks and a loss-of-resistance test. The obturator and lateral cutaneous femoral nerves were located by the use of superficial anatomic landmarks. Following perineural administration of 3 volumes (0.1, 0.2, and 0.3 mL/kg) of staining solution near the target nerves in 15 cadavers, the distribution of the staining solution along the nerves was evaluated. Staining that extended ≥ 2 cm along the target nerves was considered to be compatible with an effective clinical nerve block. RESULTS In all cadavers, nerves were appropriately stained by the blind techniques used here. The staining distribution along the nerves was considered to be optimal after perineural injection of 0.2 mL of staining solution/kg in the obturator and lateral cutaneous femoral nerves and 0.3 mL of staining solution/kg in the saphenous nerve. CONCLUSIONS AND CLINICAL RELEVANCE Results indicated that the evaluated blind perineural injection techniques may be an inexpensive, safe, and clinically effective method to block the saphenous, obturator, and lateral cutaneous femoral nerves in dogs.


Assuntos
Cães , Nervo Femoral , Bloqueio Nervoso/veterinária , Nervo Obturador , Animais , Cadáver , Cães/anatomia & histologia , Vias de Administração de Medicamentos , Humanos , Injeções , Coloração e Rotulagem/veterinária
10.
Acta Chir Plast ; 59(2): 65-71, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29446305

RESUMO

INTRODUCTION: Peripheral nerve injury is a frequently encountered clinical problem that leads to functional losses at the long-term. Although microsurgical repair has been introduced to clinical practice in peripheral nerve injuries, unsatisfactory outcomes regarding functional recovery in target organ cause an increasing interest on studies about nerve injury and biology of the recovery in nerve injuries1. MATERIAL AND METHODS: Sciatic nerves of seventy adult Sprague Dewly rats were transected and primary anastomosis was performed. Rats were then divided into three groups: Control group, while 30 rats were repaired with sutures, and the remaining 30 were repaired with fibrin glue. After 30 days the rats were sacrified and the sciatic nerves were investigated histologically with morphometrical and statistical analyses. RESULTS: In microsurgical nerve repair, suture placement has been thought to cause hindrance to the sprouting axons and compress the blood supply to the fascicles, thereby impairing the regeneration of the transected nerve ends after repair, with possible neuroma formation. On the other hand, fibrin glue is a simple, effective technique, less time consuming than suturing. Another advantage of this suture-free technique is that it avoids injuring the axon with needles, and the lack of foreign bodies minimizes the inflammatory reaction. CONCLUSION: We recommend using fibrin glue as it demonstrates less inflammatory reaction, less scar tissue formation, it is less time consuming and provides better outcomes.


Assuntos
Nervo Femoral , Adesivo Tecidual de Fibrina , Nervo Isquiático , Anastomose Cirúrgica , Animais , Ratos , Ratos Sprague-Dawley , Nervo Isquiático/cirurgia , Suturas
12.
Zhonghua Yi Xue Za Zhi ; 96(35): 2813-2817, 2016 Sep 20.
Artigo em Chinês | MEDLINE | ID: mdl-27686548

RESUMO

Objective: To assess the pain control efficiency of continuous adductor canal block in total knee arthroplasty. Methods: From October to December 2015, patients with severe knee osteoarthritis undergoing primary unilateral TKA were observed clinically.All of the patients received ultrasound-guided continuous adductor canal block after surgery.NPRS Pain score in rest and activity at 2, 6, 12, 24, 48 h after surgery were collected, preoperative and postoperative quadriceps strength at 24, 48 h were analyzed. Opioids consumption and anesthesia related adverse effects were also recorded. Results: All of the patients were enrolled. Rest pain control was fairly good(1.8±1.5), (2.4±1.5), (2.7±1.3), (2.7±1.7), (2.3±1.4) score, but the patients were not satisfied with activity pain control(3.1±2.1), (3.1±2.1), (4.2±2.2), (4.7±2.5), (6.2±2.4) score. There were statistically differences comparing the NPRS in rest pain with the score in activity, except for the results between each other at 6 hours (P=0.252>0.05)after surgery.The results showed no significant differences comparing quadriceps strengthpreoperatively with 24, 48 h postoperatively by repeated measurements variance analysis.Eight patients acquired additional use of dolantin once (100 mg/per time) within 24 h and among them three patients acquired once dolantin during 24 to 48 h. Eleven patients complained nausea postoperatively, one reported vomiting and one experienced xerostomia. Conclusion: Ultrasound-guided continuous adductor canal block can reduce resting pain after TKA, but has a limited effect in activity pain control.Quadriceps strength had been spared after ACB, which might performearly benefits in rehabilitation. ACB-related complications need further observation to be defined.


Assuntos
Artroplastia do Joelho , Nervo Femoral , Dor Pós-Operatória , Analgésicos Opioides , Humanos , Músculo Esquelético , Bloqueio Nervoso , Manejo da Dor , Medição da Dor , Náusea e Vômito Pós-Operatórios , Ultrassonografia
13.
J Arthroplasty ; 30(12): 2076-81, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26205089

RESUMO

There is general agreement that femoral nerve blocks (FNB) provide adequate immediate postoperative analgesia after total knee arthroplasty (TKA), although the effect of this technique on hospital readmission and other complications has not been quantified in a large sample. The Medicare 5% sample was used to identify TKA patients who were grouped according to postoperative FNB administration: FNB via injection; FNB via pain pump; and no FNB. Multivariate Cox regressions were used to evaluate risk factors for the postoperative outcomes. Both FNB groups were associated with a lower risk of readmission (30, 90 and 365 days, P<0.001). Future clinical studies may help elucidate whether the lower hospital readmissions may be associated with more effective pain control with the use of FNB.


Assuntos
Artroplastia do Joelho/efeitos adversos , Nervo Femoral , Bloqueio Nervoso/métodos , Dor Pós-Operatória/prevenção & controle , Readmissão do Paciente/estatística & dados numéricos , Idoso , Idoso de 80 Anos ou mais , Catéteres/efeitos adversos , Feminino , Humanos , Injeções , Masculino , Medicare , Dor Pós-Operatória/etiologia , Estudos Retrospectivos , Estados Unidos
15.
J Anesth ; 29(2): 303-7, 2015 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25217117

RESUMO

Adductor canal catheters preserve quadriceps strength better than femoral nerve catheters and may facilitate postoperative ambulation following total knee arthroplasty. However, the effect of this newer technique on provider workload, if any, is unknown. We conducted a retrospective provider workload analysis comparing these two catheter techniques; all other aspects of the clinical pathway remained the same. The primary outcome was number of interventions recorded per patient postoperatively. Secondary outcomes included infusion duration, ambulation distance, opioid consumption, and hospital length of stay. Adductor canal patients required a median (10-90th percentiles) of 0.0 (0.0-2.6) interventions compared to 1.0 (0.3-3.0) interventions for femoral patients (p < 0.001); 18/23 adductor canal patients (78 %) compared to 2/22 femoral patients (9 %) required no interventions (p < 0.001). Adductor canal catheter infusions lasted 2.0 (1.4-2.0) days compared to 1.5 (1.0-2.7) days in the femoral group (p = 0.016). Adductor canal patients ambulated further [mean (SD)] than femoral patients on postoperative day 1 [24.5 (21.7) vs. 11.9 (14.6) meters, respectively; p = 0.030] and day 2 [44.9 (26.3) vs. 22.0 (22.2) meters, respectively; p = 0.003]. Postoperative opioid consumption and length of stay were similar between groups. We conclude that adductor canal catheters offer both patient and provider benefits when compared to femoral nerve catheters.


Assuntos
Anestesia Local/métodos , Artroplastia do Joelho/métodos , Catéteres , Nervo Femoral , Pessoal de Saúde/estatística & dados numéricos , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/terapia , Coxa da Perna , Carga de Trabalho/estatística & dados numéricos , Idoso , Idoso de 80 Anos ou mais , Analgésicos Opioides/administração & dosagem , Analgésicos Opioides/uso terapêutico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Força Muscular , Complicações Pós-Operatórias/economia , Estudos Retrospectivos , Resultado do Tratamento , Caminhada
16.
Muscle Nerve ; 51(1): 117-24, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-24752594

RESUMO

INTRODUCTION: In this study we evaluated the validity of garment-based quadriceps stimulation (GQS) for assessment of muscle inactivation in comparison with femoral nerve stimulation (FNS). METHODS: Inactivation estimates (superimposed doublet torque), self-reported discomfort, and twitch and doublet contractile properties were compared between GQS and FNS in 15 healthy subjects. RESULTS: Superimposed doublet torque was significantly lower for GQS than for FNS at 20% and 40% maximum voluntary contraction (MVC) (P < 0.01), but not at 60%, 80%, and 100% MVC. Discomfort scores were systematically lower for GQS than for FNS (P < 0.05). Resting twitch and doublet peak torque were lower for GQS, and time to peak torque was shorter for GQS than for FNS (P < 0.01). CONCLUSIONS: GQS can be used with confidence for straightforward evaluation of quadriceps muscle inactivation, whereas its validity for assessment of contractile properties remains to be determined.


Assuntos
Fenômenos Biofísicos/fisiologia , Estimulação Elétrica , Contração Muscular/fisiologia , Músculo Quadríceps/fisiologia , Adulto , Análise de Variância , Eletromiografia , Exercício Físico , Feminino , Nervo Femoral/fisiologia , Humanos , Masculino , Percepção da Dor/fisiologia , Treinamento Resistido , Torque , Adulto Jovem
17.
Anesthesiology ; 121(2): 239-48, 2014 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-24758775

RESUMO

BACKGROUND: Ultrasound guidance for continuous femoral perineural catheters may be supplemented by electrical stimulation through a needle or through a stimulating catheter. The authors tested the primary hypothesis that ultrasound guidance alone is noninferior on both postoperative pain scores and opioid requirement and superior on at least one of the two. Second, the authors compared all interventions on insertion time and incremental cost. METHODS: Patients having knee arthroplasty with femoral nerve catheters were randomly assigned to catheter insertion guided by: (1) ultrasound alone (n = 147); (2) ultrasound and electrical stimulation through the needle (n = 152); or (3) ultrasound and electrical stimulation through both the needle and catheter (n = 138). Noninferiority between any two interventions was defined for pain as not more than 0.5 points worse on a 0 to 10 verbal response scale and for opioid consumption as not more than 25% greater than the mean. RESULTS: The stimulating needle group was significantly noninferior to the stimulating catheter group (difference [95% CI] in mean verbal response scale pain score [stimulating needle vs. stimulating catheter] of -0.16 [-0.61 to 0.29], P < 0.001; percentage difference in mean IV morphine equivalent dose of -5% [-25 to 21%], P = 0.002) and to ultrasound-only group (difference in mean verbal response scale pain score of -0.28 [-0.72 to 0.16], P < 0.001; percentage difference in mean IV morphine equivalent dose of -2% [-22 to 25%], P = 0.006). In addition, the use of ultrasound alone for femoral nerve catheter insertion was faster and cheaper than the other two methods. CONCLUSION: Ultrasound guidance alone without adding either stimulating needle or needle/catheter combination thus seems to be the best approach to femoral perineural catheters.


Assuntos
Cateterismo/métodos , Nervo Femoral/diagnóstico por imagem , Bloqueio Nervoso/métodos , Ultrassonografia de Intervenção/métodos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Analgésicos Opioides/administração & dosagem , Analgésicos Opioides/uso terapêutico , Artroplastia do Joelho/métodos , Cateterismo/economia , Controle de Custos , Custos e Análise de Custo , Estimulação Elétrica , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Morfina/administração & dosagem , Morfina/uso terapêutico , Agulhas , Bloqueio Nervoso/economia , Manejo da Dor , Medição da Dor/efeitos dos fármacos , Dor Pós-Operatória/prevenção & controle , Tamanho da Amostra , Resultado do Tratamento , Adulto Jovem
18.
Surg Endosc ; 28(8): 2277-301, 2014 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-24609699

RESUMO

Fecal incontinence is a frequent and debilitating condition that may result from a multitude of different causes. Treatment is often challenging and needs to be individualized. During the last several years, new technologies have been developed, and others are emerging from clinical trials to commercialization. Although their specific roles in the management of fecal incontinence have not yet been completely defined, surgeons have access to them and patients may request them. The purpose of this project is to put into perspective, for both the patient and the practitioner, the relative positions of new and emerging technologies in order to propose a treatment algorithm.


Assuntos
Incontinência Fecal/terapia , Canal Anal/inervação , Canal Anal/cirurgia , Órgãos Artificiais , Ablação por Cateter , Descompressão Cirúrgica , Dextranos/uso terapêutico , Procedimentos Cirúrgicos do Sistema Digestório/métodos , Terapia por Estimulação Elétrica , Nervo Femoral/cirurgia , Fármacos Gastrointestinais/uso terapêutico , Humanos , Ácido Hialurônico/uso terapêutico , Injeções , Plexo Lombossacral , Imãs , Microesferas , Síndromes de Compressão Nervosa/cirurgia , Transferência de Nervo , Nervo Pudendo/cirurgia , Mecanismo de Reembolso , Telas Cirúrgicas , Nervo Tibial
19.
Muscle Nerve ; 50(3): 401-6, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24375237

RESUMO

INTRODUCTION: We investigated whether muscle endurance differs between IIM patients and controls and if a relationship exists between perceived fatigue and poor muscle endurance. METHODS: Quadriceps contractility, measured using femoral nerve stimulation (TwQ), and strength, measured using maximal voluntary contraction (MVCQ), were assessed in 20 IIM patients and matched controls. Quadriceps endurance was assessed using repetitive electrical stimulation (3 minutes). Time for force to fall to 70% initial force was determined (T70). Reported fatigue was measured using the FACIT-F/Fatigue Severity Scales. RESULTS: TwQ and MVCQ were lower and perceived fatigue greater for patients. There was no difference in T70 between groups. No relationships were observed between perceived fatigue and endurance (T70). CONCLUSIONS: IIM patients reported more fatigue and were weaker than controls, but there was no difference in muscle endurance. Endurance and strength were unrelated to reported fatigue measures. Mechanisms driving perceived IIM fatigue are likely to be multifactorial.


Assuntos
Fadiga Muscular/fisiologia , Músculo Esquelético/fisiopatologia , Doenças Musculares/fisiopatologia , Miosite/fisiopatologia , Resistência Física/fisiologia , Adulto , Idoso , Creatina Quinase/metabolismo , Interpretação Estatística de Dados , Dermatomiosite/fisiopatologia , Estimulação Elétrica , Feminino , Nervo Femoral/fisiologia , Humanos , Doenças Pulmonares Intersticiais/fisiopatologia , Masculino , Pessoa de Meia-Idade , Contração Muscular/fisiologia , Força Muscular/fisiologia , Músculo Quadríceps/fisiologia , Inquéritos e Questionários
20.
Rev. bras. anestesiol ; Rev. bras. anestesiol;63(6): 483-491, nov.-dez. 2013. ilus, tab
Artigo em Português | LILACS | ID: lil-697206

RESUMO

JUSTIFICATIVA E OBJETIVOS: A operação de reconstrução do ligamento cruzado anterior do joelho (RLCA) pode ter pós-operatório doloroso. O objetivo principal deste estudo foi avaliar se o emprego do bloqueio do nervo femoral (BNF) associado à raquianestesia melhoraria o tratamento da dor pós-operatória na RLCA; os objetivos secundários foram avaliar solicitação do tramadol e eventos adversos. MÉTODO: 53 pacientes foram divididos aleatoriamente nos grupos A e B. No Grupo A, 26 receberam raquianestesia e no Grupo B, 27 receberam raquianestesia e BNF. Todos receberam analgesia multimodal e poderiam solicitar analgésico de resgate a qualquer momento. As avaliações ocorreram em 6, 12 e 24 horas. RESULTADOS: Os grupos não apresentaram diferenças quanto às variáveis demográficas e clínico-cirúrgicas. A intensidade da dor não mostrou diferença entre os grupos. Escores médios de dor foram mais elevados 12 horas no Grupo A e não houve variação no Grupo B; 55,6% relataram dor moderada no Grupo A e 53,8% dor leve no Grupo B. Não houve diferença na solicitação de tramadol. Os eventos adversos não foram graves: 80,8% dos pacientes do Grupo B apresentaram bloqueio motor da coxa e dois caíram. CONCLUSÕES: A analgesia foi mais efetiva com a associação de raquianestesia e BNF, que permitiu melhor controle da dor pós-operatória na avaliação em 12 horas após a anestesia. Não houve diferença na solicitação do tramadol. Os eventos adversos apresentados pelos pacientes neste estudo não foram graves, porém deve-se estar atento à paralisia motora e à possibilidade de queda dos pacientes quando o BNF for feito.


BACKGROUND AND OBJECTIVES: Knee anterior cruciate ligament reconstruction (ACLR) may be painful in the postoperative period. The primary objective of this study was to evaluate whether the use of femoral nerve block (FNB) associated with spinal anesthesia would improve the postoperative pain treatment in ACLR and the secondary objectives were to evaluate tramadol request and adverse events. METHOD: 53 patients were randomly divided into two groups: GA (n =26) received spinal anesthesia and GB (n = 27) received spinal anesthesia and FNB. All patients received multimodal analgesia and rescue analgesics could be requested anytime. Assessments were performed at 6, 12 and 24 hours. RESULTS: There was no difference between both groups regarding demographic and clinical-surgical variables. There was no difference between groups regarding pain intensity. Mean pain scores were higher at 12 hours in GA and there was no change in GB; 55.6% of patients reported moderate pain in GA and 53.8% mild pain in GB. There was no difference regarding tramadol request. There were no serious adverse events: 80.8% of patients in GB had motor block of the thigh and two fell. CONCLUSIONS: Analgesia was more effective with the combination of spinal and FNB, which allowed better control of postoperative pain, assessed 12 hours after anesthesia. There was no difference in tramadol request. Patients in this study had no serious adverse events; however, one must be attentive to motor paralysis and the possibility of falling when FNB is performed.


JUSTIFICATIVA Y OBJETIVOS: La operación de reconstrucción del ligamento cruzado anterior de la rodilla (RLCA) puede tener un postoperatorio doloroso. El objetivo principal de este estudio fue evaluar si el empleo del bloqueo del nervio femoral (BNF) asociado con la raquianestesia mejoraría el tratamiento del dolor Postoperatorio en la RLCA. Los objetivos secundarios eran evaluar la solicitación del tramadol y eventos adversos. MÉTODO: Cincuenta y tres pacientes fueron divididos aleatoriamente en los grupos A y B. En el Grupo A, 26 recibieron raquianestesia y en el Grupo B, 27 recibieron raquianestesia y BNF. Todos recibieron analgesia multimodal y podrían solicitar analgésico de rescate a cualquier momento. Las evaluaciones se dieron en 6, 12 y 24 horas. RESULTADOS: Los grupos no presentaron diferencias en cuanto a las variables demográficas y clínico-quirúrgicas. La intensidad del dolor no arrojó diferencia entre los grupos. Las puntuaciones promedios de dolor fueron más elevadas 12 horas en el Grupo A y no hubo variación en el Grupo B; 55,6% relataron dolor moderado en el Grupo A y 53,8% dolor leve en el Grupo B. No hubo diferencia en la solicitación de tramadol. Los eventos adversos no fueron graves: 80,8% de los pacientes del Grupo B tenían bloqueo motor del muslo y dos se cayeron. CONCLUSIONES: La analgesia fue más efectiva con la asociación de la raquianestesia y BNF, lo que permitió un mejor control del dolor postoperatorio en la evaluación en 12 horas después de la anestesia. No hubo diferencia en la solicitación del tramadol. Los eventos adversos presentados por los pacientes en este estudio no fueron graves, pero debemos estar atentos a la parálisis motora y a la posibilidad de alguna caída de los pacientes cuando el BNF se realice.


Assuntos
Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Reconstrução do Ligamento Cruzado Anterior , Artroscopia/métodos , Bloqueio Nervoso , Dor Pós-Operatória/terapia , Raquianestesia , Nervo Femoral , Bloqueio Nervoso/efeitos adversos
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